Serological and molecular prevalence of hepatitis E virus among blood donors from Uruguay.

abstract：:We report a real-life 3D therapy failure in a patient treated with ombitasvir (OMV)/paritaprevir/ritonavir and dasabuvir without ribavirin (3D-R). He had therapy failure at week 12 after the end of treatment. We detected resistance-associated substitutions (RASs) plus polymorphisms on NS3, NS5A, and NS5B target region...

journal_title：Journal of medical virology

authors： Marascio N,Pavia G,Romeo I,Talarico C,Di Salvo S,Reale M,Marano V,Barreca GS,Fabiani F,Perrotti N,De Siena M,Giancotti F,Gravina T,Alcaro S,Artese A,Torti C,Liberto MC,Focà A

更新日期：2018-07-01 00:00:00

abstract：:The polymerase chain reaction (RNA-PCR) was used for specific detection of respiratory syncytial virus (RSV) genomes in clinical specimens. A set of primers was selected from conserved regions of the 1B and N genes for detection of both subgroups. The primers were found to be RSV specific, all RSV strains generated a ...

journal_title：Journal of medical virology

authors： van Milaan AJ,Sprenger MJ,Rothbarth PH,Brandenburg AH,Masurel N,Claas EC

更新日期：1994-09-01 00:00:00

abstract：:The contribution of viruses to lower respiratory tract disease in sub-Saharan Africa where human immunodeficiency virus may exacerbate respiratory infections is not well defined. No data exist on some of these viruses for Southern Africa. Comprehensive molecular screening may define the role of these viruses as single...

journal_title：Journal of medical virology

authors： Venter M,Lassaunière R,Kresfelder TL,Westerberg Y,Visser A

更新日期：2011-08-01 00:00:00

abstract：:A sensitive and specific nonradioactive in situ hybridization method capable of detecting single-copy integrated hepatitis B virus (HBV) DNA sequences in hepatocellular carcinoma (HCC) cell lines was developed. In situ hybridization of biotinylated HBV (adr, adw) DNA probes with nine different human HCC cell lines wer...

journal_title：Journal of medical virology

authors： Tay N,Chan SH,Ren EC

更新日期：1990-04-01 00:00:00

abstract：:West Nile virus (WNV) activity has fluctuated in the south-central United States since its introduction. Seasonal outbreaks are common, with three in Oklahoma during 2003, 2007, and 2012. Morbidity and mortality rates vary during each outbreak. Long-term neurologic sequelae in association with West Nile virus disease ...

journal_title：Journal of medical virology

authors： Johnson MG,Adams J,McDonald-Hamm C,Wendelboe A,Bradley KK

更新日期：2015-10-01 00:00:00

abstract：:A simple method is described for the precise quantification of infectious duck hepatitis B virus (DHBV) in cell culture, using a radioimmunofocus assay (RIFA). Primary duck hepatocyte cell cultures were infected with serial dilutions of viral samples as for a plaque assay, but then maintained with liquid overlay mediu...

journal_title：Journal of medical virology

authors： Anderson DA,Grgacic EV,Luscombe CA,Gu X,Dixon R

更新日期：1997-08-01 00:00:00

abstract：:Development of hepatitis B virus (HBV)-resistant strains following nucleos(t)ide analog treatment is a major medical concern. This report describes a case of an adult patient with chronic HBV infection, sequentially treated with the nucleos(t)ide analogues, lamivudine, adefovir, and entecavir. During monotherapy with ...

journal_title：Journal of medical virology

authors： Rodriguez-Frias F,Jardi R,Schaper M,Gimferrer M,Elefsiniotis I,Tabernero D,Esteban R,Buti M

更新日期：2007-11-01 00:00:00

abstract：:The plaque reduction neutralization test (PRNT) has been used routinely in serological studies with such arenaviruses as Junin, Machupo, and Parana. However, difficulties have been encountered in using the PRNT for LCM virus, while conflicting views have been expressed about the reliability and efficacy of the test wi...

journal_title：Journal of medical virology

authors： Tomori O,Johnson KM,Kiley MP,Elliott LH

更新日期：1987-05-01 00:00:00

abstract：:HIV is among the most generically variable of human pathogens. A comprehensive and detailed description of HIV strains in the pandemic is an important foundation for diagnosis, treatment, and prevention. The current sequence database for HIV includes almost 800 complete genome sequences, documenting HIV-1 groups M, O,...

journal_title：Journal of medical virology

authors： McCutchan FE

更新日期：2006-01-01 00:00:00

abstract：:Fifty-three (96%) of 55 patients with coronary artery stenosis were positive for serum anti-HHV-6 IgG, and 50 (91%) of these patients had anti-HHV-7 IgG. The number of cases sero-positive for HHV-6 and -7 in the 54 age matched control volunteers was 52 (96%) and 53 (98%), respectively. No statistical difference in the...

journal_title：Journal of medical virology

authors： Ihira M,Yoshikawa T,Ishii J,Nomura M,Hishida H,Ohashi M,Enomoto Y,Suga S,Iida K,Saito Y,Nishiyama Y,Asano Y

更新日期：2002-08-01 00:00:00

abstract：:Rhinovirus (RV) is a common respiratory viral infection linked to worsening of chronic respiratory diseases including cystic fibrosis (CF) and asthma. RV was tested by RT-PCR in samples (n = 465) collected from the upper (nasal swab, oropharyngeal suction, and sputum) and lower (bronchoalveolar washings) respiratory t...

journal_title：Journal of medical virology

authors： Stelzer-Braid S,Liu N,Doumit M,D'Cunha R,Belessis Y,Jaffe A,Rawlinson WD

更新日期：2017-08-01 00:00:00

abstract：:Acute gastroenteritis (AGE) is a common illness in both adults and children worldwide and is caused by several microorganisms including viruses, bacteria, and parasites. Rotavirus (RV), which is the main cause of AGE, can occur as a mixed infection with other viruses. The aim of this study is to assess the molecular e...

journal_title：Journal of medical virology

authors： Gibory M,Dembinski JL,Flem E,Haltbakk I,Dudman SG

更新日期：2020-05-15 00:00:00

abstract：:Cells from a leiomyosarcoma tumor (LMS-1) from a patient with the acquired immunodeficiency syndrome (AIDS) were explanted, cultured in vitro, and studied by phase-contrast microscopy for morphologic and growth characteristics, immunostaining for cell markers, EBER in situ hybridization and polymerase chain reaction f...

journal_title：Journal of medical virology

authors： Jenson HB,Montalvo EA,McClain KL,Ench Y,Heard P,Christy BA,Dewalt-Hagan PJ,Moyer MP

更新日期：1999-01-01 00:00:00

abstract：:Systemic cell-mediated responses to respiratory syncytial (RS) virus were detected, using a whole blood transformation assay, in 10 of 28 infants and children with RS virus infections during the period 1-14 days postadmission. Cell-mediated responses were unrelated to the age of the patient or the severity of illness....

journal_title：Journal of medical virology

authors： Scott R,Pullan CR,Scott M,McQuillin J

更新日期：1984-01-01 00:00:00

abstract：:The TD97 strain vaccine virus was prepared from the Tanabe strain measles virus by low-temperature passages in primary cell cultures and ultraviolet (UV) mutagenesis. The TD97 strain exhibited the following characteristics: highly temperature sensitive, neither multiplying nor forming any plaques at 40 degrees C in Ve...

journal_title：Journal of medical virology

authors： Suzuki K,Morita M,Katoh M,Kidokoro M,Saika S,Yoshizawa S,Hashizume S,Horiuchi K,Okabe N,Shinozaki T

更新日期：1990-11-01 00:00:00

abstract：:We studied epidemiologic and immunologic factors in infants with bronchiolitis caused by influenza virus. The proportion of these infants who were male and who had an immediate family member with a history of asthma was similar to that of a control group of infants with respiratory syncytial virus (RSV) bronchiolitis....

journal_title：Journal of medical virology

authors： Garofalo RP,Hintz KH,Hill V,Patti J,Ogra PL,Welliver RC Sr

更新日期：2005-02-01 00:00:00

abstract：:Primary infection, seroconversion, and transmitted drug resistance (TDR) during pregnancy may influence the risk of mother-to-child-transmission (MTCT) of HIV-1 infection. This study estimated recent seroconversion, TDR rates, HIV-1 subtypes and pregnancy outcomes among 95 recently diagnosed, antiretroviral (ARV)-naïv...

journal_title：Journal of medical virology

authors： Lima YA,Cardoso LP,Reis MN,Stefani MM

更新日期：2016-11-01 00:00:00

abstract：:Eastern equine encephalitis (EEE) is rare, but the most severe of the mosquito-borne encephalitides in the United States with a high case fatality rate of 30%. Here, we present a patient with EEE. EEE virus causes sporadic human disease in the Eastern parts of the United States, but the case we describe was a Scottish...

journal_title：Journal of medical virology

authors： Harvala H,Bremner J,Kealey S,Weller B,McLellan S,Lloyd G,Staples E,Faggian F,Solomon T

更新日期：2009-02-01 00:00:00

abstract：:A pathogenic role of precore-defective mutation in the onset of fulminant hepatitis B has been suggested. However, precore-defective mutants do not always cause fulminant hepatitis B and are not always isolated from affected patients. These findings strongly suggest the presence of some additional important mutations ...

journal_title：Journal of medical virology

authors： Kaneko M,Uchida T,Moriyama M,Arakawa Y,Shikata T,Gotoh K,Mima S

更新日期：1995-11-01 00:00:00

abstract：:Swabbing the surface of a genital lesion to obtain a sample for HPV DNA testing is less invasive than a biopsy, but may not represent HPV types present in the lesion tissue. The objective of this study was to examine the concordance of HPV types detected in swab and biopsy samples from 165 genital lesions from men age...

journal_title：Journal of medical virology

authors： Anic GM,Messina JL,Stoler MH,Rollison DE,Stockwell H,Villa LL,Lazcano-Ponce E,Gage C,Silva RJ,Baggio ML,Salmerón J,Giuliano AR

更新日期：2013-09-01 00:00:00

abstract：:The effect of different formulations of interferon on therapeutic response in patients coinfected with HIV and HCV is unclear. In this study, the safety, tolerability, viral kinetics (VK) modeling and host responses among HIV/HCV coinfected patients treated with pegylated-IFN or albinterferon alfa-2b (AlbIFN) with wei...

journal_title：Journal of medical virology

authors： Osinusi A,Bon D,Nelson A,Lee YJ,Poonia S,Shivakumar B,Cai SY,Wood B,Haagmans B,Lempicki R,Herrmann E,Sneller M,Polis M,Masur H,Kottilil S

更新日期：2014-02-01 00:00:00

abstract：:The nucleotide sequence of 10 isolates of human parvovirus B19 (B19) were determined and compared throughout 96.3% of the open reading frames (4145 nucleotides from nt. 509-4653). In the 4145 nucleotides, 122 mutation sites were found, of which 24 were accompanied by amino acid displacement. Furthermore, the polymorph...

journal_title：Journal of medical virology

authors： Fukada K,Matumoto K,Takakura F,Yamaki M,Sato H,Okochi K,Maeda Y

更新日期：2000-09-01 00:00:00

abstract：:It have been suggested that hepatitis B virus (HBV) pre-S deletions may play a role in hepatocarcinogenesis. The aim of the study was to determine the prevalence of pre-S deletions in chronic hepatitis B patients in Hong Kong, the factors associated with the deletions and its relationship with hepatitis B e antigen (H...

journal_title：Journal of medical virology

authors： Yeung P,Wong DK,Lai CL,Fung J,Seto WK,Yuen MF

更新日期：2010-11-01 00:00:00

abstract：:Distinct human papillomavirus (HPV) 18 variants are thought to differ in oncogenic potential and geographic distribution. As such, understanding the regional variants of HPV 18 would be of great importance for evolutionary, epidemiological, and biological analysis. In this regard, the sequence variations of E6 gene we...

journal_title：Journal of medical virology

authors： Salavatiha Z,Shoja Z,Heydari N,Marashi SM,Younesi S,Nozarian Z,Jalilvand S

更新日期：2020-07-09 00:00:00

abstract：:Enterovirus D68 (EV-D68) is an emergent viral pathogen associated with mild to severe respiratory infections. In this study, we describe respiratory infections associated with EV-D68 in Beijing over a 4 year period. Total nucleic acid was extracted from 7,945 clinical specimens collected between January 5, 2011 and Ju...

journal_title：Journal of medical virology

authors： Zhang T,Li A,Chen M,Wu J,Huang F

更新日期：2016-09-01 00:00:00

abstract：:Nucleotide sequences of the hypervariable region (HVR) of the E2/NS1 gene of hepatitis C virus (HCV), which are now thought to contain epitopes for neutralizing antibodies, were compared between antibody-bound HCV and free HCV in a patient with type II cryoglobulinemia. Antibody-bound HCV was immunoprecipitated with a...

journal_title：Journal of medical virology

authors： Kurosaki M,Enomoto N,Nouchi T,Sakuma I,Marumo F,Sato C

更新日期：1995-08-01 00:00:00

abstract：:Rapid PCR-based influenza tests are increasingly used as point-of-care diagnostics in hospitals and clinics. To our knowledge, no prior studies have described clinical outcomes with implementation of rapid PCR-based influenza tests in hospitalized adult inpatients. Electronic medical records were used to assess differ...

journal_title：Journal of medical virology

authors： Chu HY,Englund JA,Huang D,Scott E,Chan JD,Jain R,Pottinger PS,Lynch JB,Dellit TH,Jerome KR,Kuypers J

更新日期：2015-12-01 00:00:00

abstract：:ZIKV infection has become a global threat spreading across 31 countries in Central America, South America, and the Caribbean. However, little information is available about the molecular epidemiology of ZIKV. Shared mutation of a threonine residue to alanine at the same position in the C terminal of NS5 sequences was ...

journal_title：Journal of medical virology

authors： Adiga R

更新日期：2016-10-01 00:00:00

abstract：:Among 39,656 voluntary blood donors in Okinawa Prefecture, Japan, 115 (0.29%) were repeatedly reactive for antibody to hepatitis C virus (anti-HCV) by second generation (2nd-gen) passive hemagglutination assay (PHA). Positive serum samples were tested for anti-HCV using three different enzyme immunosorbent assays (ELI...

journal_title：Journal of medical virology

authors： Sakugawa H,Nakasone H,Nakayoshi T,Kinjo F,Saito A,Yakabi S,Zukeran H,Miyagi Y,Taira R,Koja K

更新日期：1995-08-01 00:00:00

abstract：:Influenza epidemic is an important cause of severe illness in the elderly. Age-dependent morbidity of influenza in the elderly is associated with weakened immunity. The baseline age-related memory T cell activity in Chinese persons who are exposed to influenza virus through natural infection, are associated with the p...

journal_title：Journal of medical virology

authors： Jia N,Li C,Liu YX,Richardus JH,Feng D,Yang H,Dang RL,Ma YH,Xu XN,Cao WC

更新日期：2009-08-01 00:00:00