Abstract:
:Systemic cell-mediated responses to respiratory syncytial (RS) virus were detected, using a whole blood transformation assay, in 10 of 28 infants and children with RS virus infections during the period 1-14 days postadmission. Cell-mediated responses were unrelated to the age of the patient or the severity of illness. No correlation was found between cellular responses and fourfold or greater rises in antibody titre to RS virus, as determined by a membrane immunofluorescence technique. Patients under 6 months of age had significantly lower levels of IgA and IgG antibody to RS virus compared to older patients, although cell-mediated responses were similar in both groups. The presence of cell-mediated reactivity to RS virus was also demonstrated in 5 of 95 samples of cord blood examined, and cellular responses failed to correlate with the levels of IgG antibody to RS virus.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Scott R,Pullan CR,Scott M,McQuillin Jdoi
10.1002/jmv.1890130112subject
Has Abstractpub_date
1984-01-01 00:00:00pages
105-14issue
1eissn
0146-6615issn
1096-9071journal_volume
13pub_type
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journal_title:Journal of medical virology
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journal_title:Journal of medical virology
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更新日期:2009-03-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
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journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:2009-09-01 00:00:00
abstract::Human metapneumovirus (hMPV) is considered an important cause of acute respiratory infections. hMPV can cause morbidity in hematopoietic stem cell transplant recipients and recent research has demonstrated that it is an important virus in patients admitted to hospital with respiratory infections and suspected of havin...
journal_title:Journal of medical virology
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journal_title:Journal of medical virology
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更新日期:2014-09-01 00:00:00
abstract::The criterion standard for the diagnosis of occult hepatitis C virus (HCV) infection is detection of HCV-RNA in liver cells. However, because of the invasive nature of liver biopsy, other methods have been studied. The present study aimed to identify subjects with occult HCV-4 infection among healthy sexual partners o...
journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:2015-03-01 00:00:00
abstract:PROBLEM:Objective studies that use validated questionnaires are needed to evaluate the changes in the sexual functions of women diagnosed with human papillomavirus (HPV) infection. METHOD OF STUDY:The study comprised 80 sexually active women diagnosed with a high-risk HPV infection. These patients were divided into fo...
journal_title:Journal of medical virology
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abstract::A small percentage of renal patients become infected with the BK polyomavirus (BKV), a pathogenic virus that causes BKV-associated nephropathy (BKVN), after kidney transplantation. This study presents a simple, rapid, high-throughput method for BKV genotyping using high-resolution melt analysis (HRMA). Using this nove...
journal_title:Journal of medical virology
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更新日期:2011-12-01 00:00:00
abstract::Individuals infected with HIV have higher circulating Epstein-Barr virus (EBV) DNA load compared to healthy carriers. This study investigated whether level of spontaneous immunoglobulin secreting cells, one of the major hallmarks of HIV infection, is associated with an increase of EBV DNA load in PBMCs and the spontan...
journal_title:Journal of medical virology
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journal_title:Journal of medical virology
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更新日期:2001-07-01 00:00:00
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更新日期:1988-07-01 00:00:00
abstract::The effects of tumor necrosis factor-alpha and/or interferon-gamma on the replication of hepatitis B virus were examined using HB611 cells. These cells were derived from human hepatoblastoma cells, Huh6, by integrating hepatitis B virus DNA, and produce hepatitis B virus continuously. Each of the cytokines inhibited h...
journal_title:Journal of medical virology
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更新日期:1995-11-01 00:00:00
abstract::Severe hemorrhagic fever disease is caused by severe fever with thrombocytopenia syndrome virus (SFTSV) infection, which belongs to the Phlebovirus genus in the Bunyaviridae family. A comprehensive literature search of PubMed, Web of Science, Embase, Cochrane Library, Chinese National Knowledge Infrastructure database...
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abstract::Puumala hantavirus (PUUV) glycoproteins G1 and G2 and nucleocapsid protein (N) were expressed in BHK-21 cells by transfection of a plasmid producing a recombinant alphavirus replicon. Coexpression of G1 and G2 from separate constructs seemed to be important for the optimal folding of the glycoproteins, as evaluated by...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
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abstract::The objectives of this study were to evaluate the reliability of herpes simplex virus (HSV) PCR testing in cerebrospinal fluid (CSF) for the detection of herpes simplex encephalitis. This was done by examining retrospectively the clinical follow-up of a large group of patients tested routinely by HSV-PCR. In addition,...
journal_title:Journal of medical virology
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更新日期:2001-08-01 00:00:00
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journal_title:Journal of medical virology
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更新日期:2009-01-01 00:00:00