Clinical and economic burden of pre-emptive therapy of cytomegalovirus infection in hospitalized allogeneic hematopoietic cell transplant recipients.

abstract：:Hemagglutination inhibition (HI), single radial hemolysis (SRH) and enzyme-linked immuno sorbent assay (ELISA), performed with commercial antigen and reagents are described and were compared in the three distinct situations that require rubella antibody detection. Determination of immunity status was carried out on 15...

journal_title：Journal of medical virology

authors： Champsaur H,Dussaix E,Tournier P

更新日期：1980-01-01 00:00:00

abstract：:Herpesviruses produce assembly proteins (AP) that act as scaffolding proteins for the assembly of the viral capsids. The products of the assemblin gene, which encodes both maturational protease and AP, have been established for herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (CMV). We cloned an inframe O...

journal_title：Journal of medical virology

authors： Garcia-Valcarcel M,Fowler WJ,Harper DR,Jeffries DJ,Layton GT

更新日期：1997-12-01 00:00:00

abstract：:The predictive value of two methods for measuring HIV RNA concentration in plasma was assessed in relation to CD4 lymphocyte counts during the asymptomatic period of infection. The design was a retrospective longitudinal case-control study for a mean period of 60 months involving 20 asymptomatic patients included in t...

journal_title：Journal of medical virology

authors： Delamare C,Burgard M,Deveau C,Chaix ML,Ivanoff S,Ramirez D,Tachet A,Bary M,Rouzioux C

更新日期：1998-01-01 00:00:00

abstract：:An outbreak of an acute sporadic viral hepatitis occurring at three villages in the lower Shebli region of southern Somalia was studied. Sera were examined for antibodies to hepatitis E virus (HEV) antigen by a recently developed enzyme-linked immunosorbent assay. The prevalence of anti-HEV ranged from 77.8% to 94.0% ...

journal_title：Journal of medical virology

authors： Mushahwar IK,Dawson GJ,Bile KM,Magnius LO

更新日期：1993-07-01 00:00:00

abstract：:Among 39,656 voluntary blood donors in Okinawa Prefecture, Japan, 115 (0.29%) were repeatedly reactive for antibody to hepatitis C virus (anti-HCV) by second generation (2nd-gen) passive hemagglutination assay (PHA). Positive serum samples were tested for anti-HCV using three different enzyme immunosorbent assays (ELI...

journal_title：Journal of medical virology

authors： Sakugawa H,Nakasone H,Nakayoshi T,Kinjo F,Saito A,Yakabi S,Zukeran H,Miyagi Y,Taira R,Koja K

更新日期：1995-08-01 00:00:00

abstract：:A solid-phase radioimmunoassay (RIA) for the detection of hepatitis B e antigen (HBeAg) and antibody (anti-HBe) was developed. The RIA was approximately 1,000-fold more sensitive than rheophoresis for HBeAg, and approximately 6,000-fold more sensitive than rheophoresis for anti-HBe. Generally, less than one-fifth of h...

journal_title：Journal of medical virology

authors： Mushahwar IK,Overby LR,Frosner G,Deinhardt F,Ling CM

更新日期：1978-01-01 00:00:00

abstract：:Twenty marmosets, male Callithrix jacchus, were used during this study. Fifteen of the marmosets were inoculated with 5,000 TCID50 of the attenuated XJC13 strain of Junin virus by intramuscular route and five were left as uninoculated controls. Animals were observed for a 420-day period. In order to carry out virologi...

journal_title：Journal of medical virology

authors： Avila MM,Frigerio MJ,Weber EL,Rondinone S,Samoilovich SR,Laguens RP,de Guerrero LB,Weissenbacher MC

更新日期：1985-01-01 00:00:00

abstract：:Human herpesvirus 6 (HHV-6) prototype isolate GS is a newly identified lymphotropic herpesvirus and several subsequent herpes isolates were recognized as HHV-6 by their hybridization to a HHV-6(GS) DNA probe pZVH14. DNA restriction analysis and in vitro tropism studies show that HHV-6 isolates can be divided into two ...

journal_title：Journal of medical virology

authors： Chandran B,Tirawatnapong S,Pfeiffer B,Ablashi DV

更新日期：1992-08-01 00:00:00

abstract：:Algeria is the largest country of Africa, peopled with populations living a range of traditional/rural and modern/urban lifestyles. The variations of prevalence of chronic active hepatitis care poorly known on the Algerian territory. We conducted a retrospective survey on all patients (n = 998) referred to our institu...

journal_title：Journal of medical virology

authors： Bensalem A,Selmani K,Hihi N,Bencherifa N,Mostefaoui F,Kerioui C,Pineau P,Debzi N,Berkane S

更新日期：2016-08-01 00:00:00

abstract：:Rotaviruses were detected via electron microscopy in fecal specimens collected from school children during an outbreak of diarrhea and from a sporadic case in 1993 in Japan. All of the viruses were found to belong to human group C rotavirus by reverse passive hemagglutination assay (RPHA). These viruses replicated wel...

journal_title：Journal of medical virology

authors： Shinozaki K,Yamanaka T,Tokieda M,Shirasawa H,Simizu B

更新日期：1996-01-01 00:00:00

abstract：:Epstein-Barr virus (EBV)-associated post-transplant lymphoproliferative disease (PTLD) arises in up to 10% of organ transplant recipients and is fatal in ∼50% of cases. PTLD can be modeled in SCID mice using EBV+ve human B lymphoblastoid cell lines (BLCLs), and the current study investigated intraperitoneal (ip) inocu...

journal_title：Journal of medical virology

authors： Johannessen I,Bieleski L,Urquhart G,Watson SL,Wingate P,Haque T,Crawford DH

更新日期：2011-09-01 00:00:00

abstract：:Because of the distinct ability of retroviruses to integrate into the target cell genome and thus achieve long-term expression, retrovirus vectors hold great promise for stable gene transfer. Such vectors derived from human immunodeficiency retroviruses (HIVs) and other lentiviruses are envisioned to possess several a...

journal_title：Journal of medical virology

authors： Sadaie MR,Zamani M,Whang S,Sistron N,Arya SK

更新日期：1998-02-01 00:00:00

abstract：:Recently, several clusters of hepatitis A have been observed among hemophiliacs linked to factor VIII concentrates treated for virus inactivation solely with the solvent/detergent (S/D) method, a procedure that does not affect nonenveloped viruses such as the hepatitis A virus (HAV). A new outbreak of hepatitis A in s...

journal_title：Journal of medical virology

authors： Chudy M,Budek I,Keller-Stanislawski B,McCaustland KA,Neidhold S,Robertson BH,Nübling CM,Seitz R,Löwer J

更新日期：1999-02-01 00:00:00

abstract：:Previous investigations of fomite transmission have focused on the presence of pathogens on inanimate objects in clinical settings. There has been limited investigation of fomite transmission in non-clinical pediatric settings where there is a high prevalence of respiratory virus infections. Over a 5 week period, this...

journal_title：Journal of medical virology

authors： Gralton J,McLaws ML,Rawlinson WD

更新日期：2015-06-01 00:00:00

abstract：:Interleukin 33 (IL-33) and soluble form of ST2 (sST2) are involved in inflammation. This study aimed to assess the role of serum IL-33 and sST2 in neonates with HCMV infection. The concentration of serum IL-33 and sST2 in 20 patients and 16 healthy controls were measure by enzyme-linked immune-sorbent assay (ELISA). T...

journal_title：Journal of medical virology

authors： Chen Y,Qian J

更新日期：2018-08-01 00:00:00

abstract：:In eight patients with biopsy-confirmed chronic active hepatitis (CAH), hepatitis B e antigen (HBeAg) levels and DNA polymerase (DNA-P) activity were assayed three times a week for six weeks and once a week for another six weeks. HBeAg levels were rather constant, whereas DNA-P activity fluctuated. No correlation was ...

journal_title：Journal of medical virology

authors： Heijtink RA,van der Waart M,Weimar W,Schalm SW,Masurel N

更新日期：1980-01-01 00:00:00

abstract：:No data on antiviral response of HBV genotypes E-H are available so far although these HBV genotypes contribute significantly to the global HBV burden. Of 49 patients with HBV genotypes E-H, 23 received interferon (IFN)-alpha, 12 nucleos(t)ide analogues and 14 patients were untreated. HBV genotype was determined by di...

journal_title：Journal of medical virology

authors： Erhardt A,Göbel T,Ludwig A,Lau GK,Marcellin P,van Bömmel F,Heinzel-Pleines U,Adams O,Häussinger D

更新日期：2009-10-01 00:00:00

abstract：:During 1999-2000, a sustained mumps outbreak in the highly vaccinated population in Singapore was attributed to vaccine failure associated with the Rubini vaccine strain. To explain this phenomenon, the complete nucleotide and amino acid sequences of the hemagglutinin-neuraminidase (HN) gene of eight mumps virus isola...

journal_title：Journal of medical virology

authors： Lim CS,Chan KP,Goh KT,Chow VT

更新日期：2003-06-01 00:00:00

abstract：:Hepatitis B virus (HBV) DNA may persist in the liver in the absence of serum HBV-DNA after a self-limited acute hepatitis B. This may also occur in patients with chronic hepatitis C virus (HCV) infection but its prevalence and its impact on liver histology is unknown. HBV-DNA was tested by polymerase chain reaction (P...

journal_title：Journal of medical virology

authors： Mariscal LF,Rodríguez-Iñigo E,Bartolomé J,Castillo I,Ortiz-Movilla N,Navacerrada C,Pardo M,Pérez-Mota A,Graus J,Carreño V

更新日期：2004-06-01 00:00:00

abstract：:At present eight hepatitis B virus (HBV) genotypes have been characterized: A to H. The most common genotype in Northern Europe is genotype A. So far there is no record of the specific HBV genotype distribution in Iceland. Iceland has a small population whose homogeneity has changed due to increasing migration during ...

journal_title：Journal of medical virology

authors： Björnsdottir TB,Stanzeit B,Sällberg M,Löve A,Hultgren C

更新日期：2005-12-01 00:00:00

abstract：:The presence of hepatitis GB virus C (GBV-C), also known as hepatitis G virus (HGV), and hepatitis C virus (HCV) were investigated in sera from 45 hemophiliacs from nine locations in Nicaragua using a nested polymerase chain reaction (PCR). Primers used to detect GBV-C and HCV derived from the helicase region and 5'UT...

journal_title：Journal of medical virology

authors： González-Pérez MA,Norder H,Bergström A,Lopéz E,Visoná KA,Magnius LO

更新日期：1997-06-01 00:00:00

abstract：:Noroviruses (NoV) and sapoviruses (SaV) are recognized as important causes of acute gastroenteritis in children worldwide. In this study, the prevalence and genetic variability of NoV and SaV were determined in hospitalized children <5 years of age with acute gastroenteritis in Hanoi, Vietnam. A total of 501 fecal spe...

journal_title：Journal of medical virology

authors： Trang NV,Luan le T,Kim-Anh le T,Hau VT,Nhung le TH,Phasuk P,Setrabutr O,Shirley H,Vinjé J,Anh DD,Mason CJ

更新日期：2012-02-01 00:00:00

abstract：:Comparison of RT-PCR assays established in house at various places revealed that laboratories could differ in sensitivity by as much as 1,000-fold in terms of the ability to detect measles virus sequences in clinical samples. The study indicates that PCR findings, positive or negative, are questionable if they are not...

journal_title：Journal of medical virology

authors： Afzal MA,Osterhaus AD,Cosby SL,Jin L,Beeler J,Takeuchi K,Kawashima H

更新日期：2003-05-01 00:00:00

abstract：:A quantitative polymerase chain reaction (PCR) assay for hepatitis C viral RNA (HCV-RNA) was used to monitor viraemia levels in six patients at multiple time points before, during, and after interferon therapy for chronic non-A, non-B hepatitis (NANBH). Prior to therapy, serum HCV-RNA was detected in all patients at a...

journal_title：Journal of medical virology

authors： Garson JA,Brillanti S,Ring C,Perini P,Miglioli M,Barbara L

更新日期：1992-07-01 00:00:00

abstract：:Glycoprotein B (gB) and glycoprotein H (gH) of human herpesvirus 7 (HHV-7) are believed to play an important role in virus entry and as targets for host immune response. This study examined the genetic diversity of these glycoproteins among 90 HHV-7 isolates collected from different individuals in Hong Kong. Overall, ...

journal_title：Journal of medical virology

authors： Chan PK,Li CK,Chik KW,Shing MM,Lee V,Ng KC,Lam CW,Cheung JL,Cheng AF

更新日期：2003-11-01 00:00:00

abstract：:Sera from patients with sandfly fever caused by Toscana virus (TOSV) infection were tested by immunoblot for specific antibody response to TOSV derived from infected Vero-E6 cells. The 28 kDa TOSV nucleoprotein (N) was identified as the major immunodominant protein recognized by immunoblot. In sera of patients with ac...

journal_title：Journal of medical virology

authors： Schwarz TF,Gilch S,Pauli C,Jäger G

更新日期：1996-06-01 00:00:00

abstract：:Interaction between herpesviruses and human immunodeficiency virus (HIV)1 is postulated in the progression of HIV disease. In order to evaluate the specific antibody responses directed to Epstein-Barr virus (EBV) and cytomegalovirus (CMV) and to provide serological evidence suggesting reactivation of these viruses abl...

journal_title：Journal of medical virology

authors： Quesnel A,Pozzetto B,Touraine F,Moja P,Lucht F,De The G,Touraine JL,Gaudin O,Genin C

更新日期：1992-01-01 00:00:00

abstract：:Human immunodeficiency virus 2 (HIV-2) infection is characterized by a slower disease progression and lower transmission rates. The molecular features that could be assigned as directly involved in this in vivo phenotype remain essentially unknown, and the importance of HIV-2 as a model to understand pathogenicity of ...

journal_title：Journal of medical virology

authors： Santos-Costa Q,Parreira R,Moniz-Pereira J,Azevedo-Pereira JM

更新日期：2009-11-01 00:00:00

abstract：:Fifty-three (96%) of 55 patients with coronary artery stenosis were positive for serum anti-HHV-6 IgG, and 50 (91%) of these patients had anti-HHV-7 IgG. The number of cases sero-positive for HHV-6 and -7 in the 54 age matched control volunteers was 52 (96%) and 53 (98%), respectively. No statistical difference in the...

journal_title：Journal of medical virology

authors： Ihira M,Yoshikawa T,Ishii J,Nomura M,Hishida H,Ohashi M,Enomoto Y,Suga S,Iida K,Saito Y,Nishiyama Y,Asano Y

更新日期：2002-08-01 00:00:00

abstract：:The rapid spread of the epidemic has aroused widespread concern in the international community. Severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) was first reported in China, with bats as the likely original hosts and pangolins as potential intermediate hosts. The current source of the disease is mainly pat...

journal_title：Journal of medical virology

authors： Ye Q,Wang B,Mao J,Fu J,Shang S,Shu Q,Zhang T

更新日期：2020-07-01 00:00:00