Antigenic relationships among human herpesvirus-6 isolates.

abstract：:The substitution of amino acid (aa) 70 of arginine for glutamine and/or that of aa91 of leucine for methionine in the core protein in patients infected with hepatitis C virus (HCV) genotype 1b is associated with a poor response to pegylated interferon and ribavirin. Factors influencing these substitutions were sought ...

journal_title：Journal of medical virology

authors： Kobayashi M,Akuta N,Suzuki F,Hosaka T,Sezaki H,Kobayashi M,Suzuki Y,Arase Y,Ikeda K,Watahiki S,Mineta R,Iwasaki S,Miyakawa Y,Kumada H

更新日期：2010-01-01 00:00:00

abstract：:Human parechoviruses (HPeVs) are prevalent in young children; however, their effects are incompletely understood. We investigated the prevalence, genotype distribution, and phylogeny of HPeVs in individuals with diarrhea (n = 430) and healthy controls (n = 93) by the analysis of stool specimens collected from July 201...

journal_title：Journal of medical virology

authors： Chen X,Shi T,Huang J,Xiao G,Huang J,Xiong Y,Li X,Chen H,Zheng X,Yu S,Chen Q

更新日期：2018-09-01 00:00:00

abstract：:Hepatitis B virus (HBV) transgenic mice that replicate HBV in the liver generally do not exhibit gross liver pathology, while maintaining a high level (10(7) or greater) of viral titer in the blood. We have used this model to determine the minimum effects of HBV replication in the liver on cellular gene transcription,...

journal_title：Journal of medical virology

authors： Hajjou M,Norel R,Carver R,Marion P,Cullen J,Rogler LE,Rogler CE

更新日期：2005-09-01 00:00:00

abstract：:It was reported previously that HCV can be transmitted from persistently infected human bone-marrow-derived B-lymphoblastoid cells (TO.FE(HCV)) to human hepatoma cells by cell-to-cell contact. The present study confirms and characterize further such type of HCV infection in vitro. TO.FE(HCV) cells were co-cultured wit...

journal_title：Journal of medical virology

authors： Valli MB,Crema A,Lanzilli G,Serafino A,Bertolini L,Ravagnan G,Ponzetto A,Menzo S,Clementi M,Carloni G

更新日期：2007-10-01 00:00:00

abstract：:Nutrient starvation is a common phenomenon that occurs during T cell activation. Upon pathogen infection, large amounts of immune cells migrate to infection sites, and antigen-specific T cells are activated; this is followed by rapid proliferation through clonal expansion. The dramatic expansion of cells will commonly...

journal_title：Journal of medical virology

authors： Lu J,Jia J,Zhang J,Liu X

更新日期：2020-08-13 00:00:00

abstract：:GB virus-B (GBV-B) is the virus most closely related to hepatitis C virus (HCV). Thus, we have used GBV-B infection of tamarins, which develop acute hepatitis following experimental infection, as a surrogate model to study protective immunity. As challenge virus, we first produced a GBV-B pool from an infected tamarin...

journal_title：Journal of medical virology

authors： Bukh J,Engle RE,Govindarajan S,Purcell RH

更新日期：2008-01-01 00:00:00

abstract：:A total of 41 stool rotavirus specimens collected from children with acute diarrhea at four different locations in Akita Prefecture, Japan, during the peak of the winter diarrhea epidemic in 1988 were analyzed by polyacrylamide gel electrophoresis of viral RNA in conjunction with subgrouping assay. We found that a sin...

journal_title：Journal of medical virology

authors： Nakagomi O,Oyamada H,Kuroki S,Kobayashi Y,Ohshima A,Nakagomi T

更新日期：1989-07-01 00:00:00

abstract：:Rapid diagnosis of human herpesvirus primary infections or reactivations is facilitated by quantitative PCRs. Quantitative PCR assays with a standard thermal cycling profile permitting simultaneous detection of herpes simplex virus (HSV), varicella zoster virus (VZV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), a...

journal_title：Journal of medical virology

authors： Engelmann I,Petzold DR,Kosinska A,Hepkema BG,Schulz TF,Heim A

更新日期：2008-03-01 00:00:00

abstract：:A total of 102,600 upper respiratory infections (URI) were recorded among young military conscripts in the Finnish Defence Forces during the study period from October 1991 to March 1994. This period covered three outbreaks caused by H3N2-subtype influenza A virus and one outbreak of influenza B. During the 1991/92 out...

journal_title：Journal of medical virology

authors： Pyhälä R,Visakorpi R,Ikonen N,Kleemola M

更新日期：2004-02-01 00:00:00

abstract：:Little information is available on the impact of direct-acting antiviral (DAA) therapy on changes in liver fibrosis and steatosis. Liver stiffness (LS) and controlled attenuation parameter (CAP) values were evaluated using transient elastography. The study subjects were 214 elderly patients infected with HCV genotype ...

journal_title：Journal of medical virology

authors： Ogasawara N,Kobayashi M,Akuta N,Kominami Y,Fujiyama S,Kawamura Y,Sezaki H,Hosaka T,Suzuki F,Saitoh S,Suzuki Y,Arase Y,Ikeda K,Kobayashi M,Kumada H

更新日期：2018-02-01 00:00:00

abstract：:Previous studies demonstrated that in vitro infection with influenza A viruses altered several functions of human monocytes-macrophages but did not detectably alter functions of human lymphocytes. However, both types of cells were infected, as determined by production and surface expression of viral antigens. In the c...

journal_title：Journal of medical virology

authors： Roberts NJ Jr,Nichols JE

更新日期：1989-03-01 00:00:00

abstract：:Several viruses are associated with gastroenteritis in infants. This pilot study, nested within a larger community-based project of early childhood infections, collected daily symptom data and 511 weekly stool samples from five healthy, fully vaccinated, term infants from birth until their second birthday. Real-time P...

journal_title：Journal of medical virology

authors： Ye S,Whiley DM,Ware RS,Sloots TP,Kirkwood CD,Grimwood K,Lambert SB

更新日期：2017-05-01 00:00:00

abstract：:The seroprevalences of hepatitis B virus (HBV) and hepatitis C virus (HCV) markers were evaluated in a random sample of 803 children attending school in Ashanti-Akim North district in Ghana in order to gain a better understanding of transmission patterns of these viruses, particularly horizontal transmission of HBV. T...

journal_title：Journal of medical virology

authors： Martinson FE,Weigle KA,Mushahwar IK,Weber DJ,Royce R,Lemon SM

更新日期：1996-03-01 00:00:00

abstract：:DNA plasmids are potent inducers of long-lasting antigen-specific CTL responses. Little is known about the distribution of antigen-specific CD8+ T cells in the lymphoid tissue and the non-lymphoid tissue after DNA immunization. HBsAg-specific CD8+ T cells in peripheral blood mononuclear cells, spleen, lymph nodes, and...

journal_title：Journal of medical virology

authors： Qu D,Lanier G,Yuan ZH,Wen YM,Howard CR,Ahmed R

更新日期：2008-02-01 00:00:00

abstract：:KI is a novel polyomavirus identified in the respiratory secretions of children with acute respiratory symptoms. Whether this reflects a causal role of the virus in the human respiratory disease remains to be established. To investigate the presence of KIV in the respiratory tissue, we examined 20 fresh lung cancer sp...

journal_title：Journal of medical virology

authors： Babakir-Mina M,Ciccozzi M,Campitelli L,Aquaro S,Lo Coco A,Perno CF,Ciotti M

更新日期：2009-03-01 00:00:00

abstract：:Hepatitis A virus infections have been reported recently among hemophilic patients in Italy and Germany, leading to speculation that infectious hepatitis A virus (HAV) might have been present in some factor VIII concentrates. In both cases, the implicated factor concentrates had been treated by a solvent/detergent met...

journal_title：Journal of medical virology

authors： Murphy P,Nowak T,Lemon SM,Hilfenhaus J

更新日期：1993-09-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) infection is an important risk factor for atherosclerosis (AS). Numerous studies have been conducted to analyze the association between HCMV infection and risk of AS, but no clear consensus has been reached. So the objective of this paper was aimed to demonstrate the relationship between H...

journal_title：Journal of medical virology

authors： Jia YJ,Liu J,Han FF,Wan ZR,Gong LL,Liu H,Zhang W,Wardell T,Lv YL,Liu LH

更新日期：2017-12-01 00:00:00

abstract：:Immunoglobulin G (IgG) and M (IgM) antibodies against mumps virus were measured by an enzyme-linked immunosorbent assay (ELISA) in the serum and cerebrospinal fluid (CSF) specimens of patients with mumps meningitis. The CSF IgG antibodies correlated well with the respective antibody titers in serum. On the contrary, i...

journal_title：Journal of medical virology

authors： Ukkonen P,Granström ML,Räsänen J,Salonen EM,Penttinen K

更新日期：1981-01-01 00:00:00

abstract：:The 70 kDa heat shock protein (Hsp70) is generally considered to be an intracellular protein, however, there is evidence that Hsp70 can be found in the extracellular environment. Hsp70 and antibodies against Hsp70 have been reported in human serum. Recent evidence has shown that Hsp70 antibodies are elevated in HIV in...

journal_title：Journal of medical virology

authors： Papp D,Prohászka Z,Kocsis J,Füst G,Bánhegyi D,Raynes DA,Guerriero V

更新日期：2005-08-01 00:00:00

abstract：:Following widespread outbreaks of oyster-associated gastroenteritis in Australia during 1978 in which Norwalk virus was implicated as the causative agent, collaborative studies were undertaken between laboratories in Australia and the United States to confirm the etiology. Immune electron microscopy (IEM) techniques w...

journal_title：Journal of medical virology

authors： Grohmann GS,Greenberg HB,Welch BM,Murphy AM

更新日期：1980-01-01 00:00:00

abstract：:Annual outbreaks of seasonal influenza cause a substantial health burden. The aim of this study was to compare patient demographic/clinical data in two influenza patient groups presenting to hospital; those requiring O2 or critical care admission and those requiring less intensive treatment. The study was conducted fr...

journal_title：Journal of medical virology

authors： Dominic C,Welch C,Melzer M

更新日期：2020-07-31 00:00:00

abstract：:Anal cancer is a rare disease. Nevertheless, it may be a reason for concern among groups in which its incidence is increasing: those who engage in anoreceptive intercourse, promiscuous persons, and those with sexually transmitted infections (HPV and HIV). The aim of this study was to evaluate the prevalence of abnorma...

journal_title：Journal of medical virology

authors： Chaves EB,Folgierini H,Capp E,von Eye Corleta H

更新日期：2012-09-01 00:00:00

abstract：:Faeces from 746 children less than 5 years old with acute gastroenteritis were screened for the presence of adenovirus particles or antigens by immunoelectron microscopy (IEM) and enzyme immunoassay (EIA). Thirty-five samples were positive by both IEM and EIA, two only by IEM, and two only by EIA, giving a total of 39...

journal_title：Journal of medical virology

authors： Leite JP,Pereira HG,Azeredo RS,Schatzmayr HG

更新日期：1985-02-01 00:00:00

abstract：:Treatment with biological drugs is associated with increased susceptibility to viral infections. Reactivation of JC virus (JCV) and human cytomegalovirus (HCMV) in adults after therapy has been documented. The long-term effects of biological and conventional therapy on human herpesviruses and polyomaviruses infections...

journal_title：Journal of medical virology

authors： Comar M,Delbue S,Lepore L,Martelossi S,Radillo O,Ronfani L,D'Agaro P,Ferrante P

更新日期：2013-04-01 00:00:00

abstract：:Hepatitis E virus sequences were detected by RT-PCR in 14/15 (93%) of untreated sewage samples from Edinburgh, Scotland, UK. Phylogenetic analysis of amplicons at limiting dilution revealed the co-circulation of multiple variants of HEV-3, with a pattern of diversity matching that observed in a local cohort of HEV-inf...

journal_title：Journal of medical virology

authors： Smith DB,Paddy JO,Simmonds P

更新日期：2016-05-01 00:00:00

abstract：:Acute gastroenteritis (AGE) is a common illness in both adults and children worldwide and is caused by several microorganisms including viruses, bacteria, and parasites. Rotavirus (RV), which is the main cause of AGE, can occur as a mixed infection with other viruses. The aim of this study is to assess the molecular e...

journal_title：Journal of medical virology

authors： Gibory M,Dembinski JL,Flem E,Haltbakk I,Dudman SG

更新日期：2020-05-15 00:00:00

abstract：:Antigenic drift of the hemagglutinin (HA) and neuraminidase (NA) proteins of the influenza virus cause a decrease in vaccine efficacy. Since the information about the evolution of these viruses in Saudi is deficient so we investigated the genetic diversity of circulating H1N1 viruses. Nasopharyngeal aspirates/swabs co...

journal_title：Journal of medical virology

authors： Naeem A,Elbakkouri K,Alfaiz A,Hamed ME,Alsaran H,AlOtaiby S,Enani M,Alosaimi B

更新日期：2020-03-11 00:00:00

abstract：:A viable virus could not be recovered from a mutant murine cytomegalovirus (MCMV) BAC in which the M34 ORF had been deleted (BACDeltaM34). In contrast, an M34 mutant virus (RcM34), in which the M34 ORF was interrupted by transposon insertion at nt 44,827 of the Smith MCMV BAC, was attenuated in replication both in tis...

journal_title：Journal of medical virology

authors： Baluchova K,Kirby M,Ahasan MM,Sweet C

更新日期：2008-07-01 00:00:00

abstract：:Herpes simplex virus (HSV) DNA in the cerebrospinal fluid (CSF) of children with herpes simplex encephalitis (HSE) was quantified and typed using the polymerase chain reaction (PCR) assay. During the acute phase, HSV-DNA was detected in the CSF of 13 patients with HSE, including 5 neonates. A restriction profile of th...

journal_title：Journal of medical virology

authors： Ando Y,Kimura H,Miwata H,Kudo T,Shibata M,Morishima T

更新日期：1993-10-01 00:00:00

abstract：:Cervical cancer is the second most common cancer among Tunisian women, and the incidence rates vary by region. Three Tunisian registries report age-standardized rates of 6.3/10(5) in the central region, 5.4/10(5) in the north, and 2.7/10(5) in the south. High-risk human papillomavirus (HPV) types and their variants di...

journal_title：Journal of medical virology

authors： KrennHrubec K,Mrad K,Sriha B,Ben Ayed F,Bottalico DM,Ostolaza J,Smith B,Tchaikovska T,Soliman AS,Burk RD

更新日期：2011-04-01 00:00:00