Abstract:
:Following widespread outbreaks of oyster-associated gastroenteritis in Australia during 1978 in which Norwalk virus was implicated as the causative agent, collaborative studies were undertaken between laboratories in Australia and the United States to confirm the etiology. Immune electron microscopy (IEM) techniques were used in Australia and radioimmunoassay (RIA) methods in the United States. Norwalk virus was detected by IEM in seven of 15 faecal samples, and four were positive by RIA. A much better correlation was found with antibody determinations. Both methods demonstrated significant increases in antibody to Norwalk virus in 22 of 30 sets (73%) of "acute" and "convalescent" sera, confirming that Norwalk virus was responsible for the majority of cases. It is significant that the RIA serology was determined using Norwalk antigen originating in the United States and the IEM serology was determined using 27--30-nm particles originating in Australia.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Grohmann GS,Greenberg HB,Welch BM,Murphy AMdoi
10.1002/jmv.1890060103subject
Has Abstractpub_date
1980-01-01 00:00:00pages
11-9issue
1eissn
0146-6615issn
1096-9071journal_volume
6pub_type
杂志文章abstract::GB Virus C (GBV-C) is a non-pathogenic flavivirus, commonly found in HIV infected patients. Studies suggest a survival benefit of GBV-C viremia in HIV infection. Impact of GBV-C viremia was evaluated on clinical outcome in multidrug-resistant HIV. The OPTIMA study enrolled advanced multidrug-resistant HIV patients wit...
journal_title:Journal of medical virology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/jmv.23845
更新日期:2014-03-01 00:00:00
abstract::The diagnosis of coronavirus disease 2019 (COVID-19) is mainly based on a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) result. PCR samples are obtained from upper or lower respiratory tract specimens. However, the sensitivity of PCR is known to have some limitat...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26153
更新日期:2020-11-01 00:00:00
abstract::Human parainfluenza viruses (HPIVs) are an important cause of acute lower respiratory tract infections (ALRTIs). HPIV-4, a newly identified virus, has been associated with severe ALRTIs recently. A total of 771 nasopharyngeal aspirate samples were collected from hospitalized children between March 2010 and February 20...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24580
更新日期:2016-12-01 00:00:00
abstract::The effects of 6-diazo-5-oxo-L-norleucine (DON), 2-deoxy-D-glucose (DOG), and tunicamycin (TM) on the replication of poliovirus (PV) and vesicular stomatitis virus (VSV) were examined. During a 48-hr replication period, TM, DON, and DOG inhibit VSV plaque formation in HEp-2 cells by 99.9%, 99.8%, and 99.9% respectivel...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890140210
更新日期:1984-01-01 00:00:00
abstract::To determine risk factors responsible for primary cytomegalovirus (CMV) infection in Taiwan, samples of blood for antibody to CMV were obtained from 362 children aged 4 to 12 years: 58% were found to be positive for anti-CMV IgG antibody. Logistic regression analysis showed that seropositivity correlated with age, met...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890370113
更新日期:1992-05-01 00:00:00
abstract::This study aimed to examine the baseline prevalence of genital human papillomavirus (HPV) infection among human immunodeficiency virus (HIV)-seropositive men who have sex with men in Taiwan and to determine the association of age and CD4+ T cell counts with HPV infection. In 2010, 305 men who have sex with men infecte...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23413
更新日期:2012-12-01 00:00:00
abstract::The effectiveness of a daily continuous infusion of interferon-alpha was evaluated in 12 patients (10 males, 2 females; mean age of 33 years, range 19-62) with biopsy-proven chronic active hepatitis C. Nine million units (MU) of recombinant interferon-alpha 2A (rIFN-alpha 2A) were administered by continuous subcutaneo...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890370312
更新日期:1992-07-01 00:00:00
abstract::In order to shed light on the mode of HTLV-I infection by mother-to-child transmission, we examined sera of school children in a highly endemic town on two separate occasions at a 6-year interval. The carrier rates in ages 15-17, 8.7 and 2.1%, were significantly higher than that in ages 6-8, 1.7 and 0.4%, in studies. ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890200307
更新日期:1986-11-01 00:00:00
abstract::A healthy patient presented to Klinikum Altmühlfranken Weißenburg Hospital, Germany, with two morning attacks of painful muscle spasm in the left upper and lower limbs, without altered consciousness. Full examinations, radiological imaging, electroencephalography, lumbar puncture, and autoimmune profile were either no...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26113
更新日期:2020-10-01 00:00:00
abstract::The presence of the E2 region of HPV 16 was determined by the polymerase chain reaction in biopsy samples with different histopathological diagnoses. The absence of the E2 gene was observed in 17 of 30 cases examined. The E2 deletions were not confined exclusively to invasive carcinomas or to integrated viral forms. I...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890410102
更新日期:1993-09-01 00:00:00
abstract::A molecular epidemiological study on common diarrheal viruses was conducted in a children's hospital in Ho Chi Minh City between December 2005 and November 2006. Fecal samples were collected from 502 pediatric patients with acute gastroenteritis, and were screened for eight types of viral agents. Human astroviruses (H...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21032
更新日期:2008-02-01 00:00:00
abstract::There are few data describing the comprehensive identification in and influence of newly identified respiratory viruses on asthma exacerbations. Most studies focus on inpatients. In this preliminary study, the point prevalence and the associations of picornavirus species described recently and human bocavirus (HBoV) w...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21819
更新日期:2010-08-01 00:00:00
abstract::Sera from 1,943 individuals from Auckland, New Zealand, were tested for the presence of serum antibodies to human T cell lymphotropic virus I (HTLV I), mainly with an enzyme-linked immunosorbent assay (ELISA) with cell extracts as target antigen. The individuals tested were blood donors and mostly Caucasian, but inclu...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890220410
更新日期:1987-08-01 00:00:00
abstract::Nineteen Chinese patients with chronic hepatitis B virus (HBV) infection, seropositive for HBV e antigen (HBeAg) and HBV DNA on at least three occasions in 6 months, were randomised to receive either recombinant human interferon-gamma (rIFN gamma) 0.1 mg/m2 intramuscularly thrice weekly for 16 weeks (n = 11) or no ant...
journal_title:Journal of medical virology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/jmv.1890340310
更新日期:1991-07-01 00:00:00
abstract::The increased immigration from developing regions to Western countries raises public health concerns related to blood-borne viruses. The prevalence of human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), and human T-lymphotropic virus (HTLV) infections among recent immigrants attending...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20744
更新日期:2006-12-01 00:00:00
abstract::Vaccine effectiveness may wane with increasing time since vaccination. This analysis used the Victorian sentinel general practitioner (GP) network to estimate vaccine effectiveness for trivalent inactivated vaccines in the 2012 season. A test-negative design was used where patients presenting to GPs with influenza-lik...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23847
更新日期:2014-06-01 00:00:00
abstract::Varicella zoster virus (VZV) causes varicella (chickenpox), after which virus becomes latent in ganglia along the entire neuraxis. Virus reactivation produces zoster (shingles). Infectious VZV is found in vesicles of patients with zoster and varicella, but virus shed in the absence of disease has not been documented. ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21173
更新日期:2008-06-01 00:00:00
abstract::Human flavivirus group-reactive, dengue complex-reactive, and encephalitis virus complex-reactive antibodies were detected using epitope-blocking immunoassays in which the binding of selected mouse monoclonal antibodies to flavivirus antigens was blocked by human serum. When late (greater than 6 months after illness) ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890230209
更新日期:1987-10-01 00:00:00
abstract::Chronic papillary conjunctivitis has been described following adenoviral conjunctivitis. It is unknown however, how long adenovirus is able to persist in the tear film and conjunctiva. To determine if adenovirus persists in the ocular surface following adenoviral conjunctivitis, 304 patients with a history of adenovir...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20440
更新日期:2005-10-01 00:00:00
abstract::This study aimed to examine the application of hepatitis B surface antigen (HBsAg) confirmatory testing when diagnosing hepatitis B infection among young persons in Taiwan with a low prevalence rate of hepatitis B infection. HBsAg status, the presence of antibodies against HBsAg (anti-HBs), and the presence of antibod...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22127
更新日期:2011-09-01 00:00:00
abstract::The impact of cytomegalovirus (CMV) infection of the genital tract during pregnancy on adverse pregnancy outcomes is not understood fully. A real-time PCR assay was used to determine vaginal shedding of CMV in 993 healthy pregnant Japanese women and the results were compared with the outcome of pregnancy. CMV DNA was ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20619
更新日期:2006-06-01 00:00:00
abstract::Most dengue virus (DENV) infections remain asymptomatic. This increases the risk of DENV transfusion transmission (TT-DENV) during outbreaks. We evaluated DENV viremia in 8475 blood donations assembled in minipools for the presence of DENV RNA. The tested samples were obtained between February and May, 2016, during a ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26619
更新日期:2020-10-22 00:00:00
abstract::The infectivity titer of a standard stock of the SAR-55 strain of hepatitis E virus (HEV) was determined in cynomolgus macaques (Macaca fascicularis) and the effect of dose on the course of the infection was examined by weekly monitoring of alanine aminotransferase (ALT) and anti-HEV levels. Antibody to HEV (anti-HEV)...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890430207
更新日期:1994-06-01 00:00:00
abstract::There are very few studies in search of an alternate and convenient diagnostic tool which can substitute nasopharyngeal swab (NPS) specimen for detection of SARS-CoV-2. In the study we analyzed, the comparison and agreement between the feasibility of using the saliva in comparison to NPS for diagnosis of SARS-CoV-2. A...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26719
更新日期:2020-12-09 00:00:00
abstract::The performance of French virology laboratories belonging to the ANRS network has been assessed annually for 3 years. The performance of these laboratories was compared between the years 2002 and 2003. Ten and 7 coded samples were sent to 38 virology laboratories in 2002 and 45 virology laboratories in 2003, respectiv...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20522
更新日期:2006-02-01 00:00:00
abstract::In vivo gene delivery using human adenovirus serotype 5 (AdV5) vectors is being explored for vaccination purposes. The presence of anti-AdV5 antibodies in human serum arising from natural exposure to AdV5 can interfere potentially with and compromise the efficacy of rAdV5-based vaccine vectors. In this report, a colle...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21721
更新日期:2010-03-01 00:00:00
abstract::Oncogenic human papillomavirus (HPV), a causative agent of uterine cervical cancer, has also been detected in head and neck squamous cell cancers, especially in squamous cell carcinomas of the tonsils. However, the true HPV prevalence in normal and neoplasic oropharyngeal mucosa remains uncertain. To determine the pre...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20583
更新日期:2006-05-01 00:00:00
abstract::To elucidate the role of host immune status in the evolution and complexity of hepatitis C virus (HCV) quasispecies, three chronic HCV-infected patients who underwent bone marrow transplantation (BMT) were studied. The three transplanted patients' sera were sampled at pre-BMT, 3 months after BMT, and 12 months after B...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9071(199906)58:2<132::aid-jmv6>
更新日期:1999-06-01 00:00:00
abstract::Influenza A/H3N2 viruses are associated with severe epidemics. Antiviral resistance and continued antigenic drift are the major concerns regarding prophylaxis and treatment of influenza. The objectives of this study were to investigate the prevalence and frequency of antiviral drug resistance in influenza A/H3N2 virus...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23854
更新日期:2014-06-01 00:00:00
abstract::Interleukin 6 (IL-6) is a pleiotropic cytokine with pivotal functions in the regulation of the biological responses of several target cells, including hepatocytes. Previous studies have shown that serum IL-6 levels are increased in hepatitis B patients. However, the role of IL-6 in modulating the anti-hepatitis B viru...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.25382
更新日期:2019-05-01 00:00:00