A randomised controlled trial of recombinant interferon-gamma in Chinese patients with chronic hepatitis B virus infection.

abstract：:A total of 102,600 upper respiratory infections (URI) were recorded among young military conscripts in the Finnish Defence Forces during the study period from October 1991 to March 1994. This period covered three outbreaks caused by H3N2-subtype influenza A virus and one outbreak of influenza B. During the 1991/92 out...

journal_title：Journal of medical virology

authors： Pyhälä R,Visakorpi R,Ikonen N,Kleemola M

更新日期：2004-02-01 00:00:00

abstract：:At present eight hepatitis B virus (HBV) genotypes have been characterized: A to H. The most common genotype in Northern Europe is genotype A. So far there is no record of the specific HBV genotype distribution in Iceland. Iceland has a small population whose homogeneity has changed due to increasing migration during ...

journal_title：Journal of medical virology

authors： Björnsdottir TB,Stanzeit B,Sällberg M,Löve A,Hultgren C

更新日期：2005-12-01 00:00:00

abstract：:To determine whether unconventional pathogens causing subacute spongiform encephalopathy may be present in blood products, a newly developed hepatitis B vaccine and a widely used blood product were injected into mice and rats. As only a few aged mice in the test and the control groups showed spongiform encephalopathic...

journal_title：Journal of medical virology

authors： Tateishi J,Tsuji S

更新日期：1985-05-01 00:00:00

abstract：:A molecular epidemiological study on common diarrheal viruses was conducted in Ho Chi Minh City, Vietnam between October 2002 and September 2003. Fecal samples were collected from 1,010 hospitalized children with acute gastroenteritis. Those samples were screened for groups A, B, and C rotavirus, adenovirus, genogroup...

journal_title：Journal of medical virology

authors： Nguyen TA,Yagyu F,Okame M,Phan TG,Trinh QD,Yan H,Hoang KT,Cao AT,Le Hoang P,Okitsu S,Ushijima H

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Human metapneumovirus (hMPV) is a recently detected virus, which can cause mild to severe respiratory tract infections. Through this study, we aimed to detail the outcomes of hMPV infections. MATERIALS/METHODS:Between January 2012 and November 2017, patients who had hMPV detected in nasopharyngeal or bronch...

journal_title：Journal of medical virology

authors： Keske Ş,Gümüş T,Köymen T,Sandıkçı S,Tabak L,Ergönül Ö

更新日期：2019-06-01 00:00:00

abstract：:Phylogenetic analysis was performed on hepatitis B virus (HBV) strains obtained from 86 hepatitis B surface antigen (HBsAg) positive donors from Thailand originating throughout the country. Based on the S gene, 87.5% of strains were of genotype C while 10.5% were of genotype B, with all genotype B strains obtained fro...

journal_title：Journal of medical virology

authors： Louisirirotchanakul S,Olinger CM,Arunkaewchaemsri P,Poovorawan Y,Kanoksinsombat C,Thongme C,Sa-Nguanmoo P,Krasae S,Theamboonlert A,Oota S,Fongsatitkul L,Puapairoj C,Promwong C,Weber B

更新日期：2012-10-01 00:00:00

abstract：:Isolated reactivity to hepatitis B virus (HBV) core antigen (anti-HBc) is observed relatively frequently in immunocompromised individuals, intravenous drug abusers (IVDA), and in the presence of HCV infection. The reason for the lack of HBsAg is not clear. The aim of the present study was to investigate which factors ...

journal_title：Journal of medical virology

authors： Weber B,Melchior W,Gehrke R,Doerr HW,Berger A,Rabenau H

更新日期：2001-07-01 00:00:00

abstract：:In mid-December 2019, a disease caused by infection with severe acute respiratory syndrome coronavirus-2, which began in Wuhan, China, has spread throughout the country and many countries around the world. The number of children with coronavirus disease-2019 (COVID-19) has also increased significantly. Although inform...

journal_title：Journal of medical virology

authors： She J,Liu L,Liu W

更新日期：2020-07-01 00:00:00

abstract：:The prevalence of coinfection and superinfection with the delta agent was studied in 2,645 hepatitis B surface antigen (HBsAg)-positive subjects from six countries and nine islands in the Western Pacific region. The study group comprised 262 patients with acute hepatitis B and 2,383 chronic carriers of HBsAg, of whom ...

journal_title：Journal of medical virology

authors： Dimitrakakis M,Crowe S,Gust I

更新日期：1986-04-01 00:00:00

abstract：:A line of hepatitis C virus (HCV) transgenic mice was established previously that was mediated by Cre/loxP system using HCV cDNA, including core, E1, E2 and NS2 genes. Intravenous infection of a recombinant adenovirus that expresses Cre DNA recombinase (AxCANCre) induced HCV structural protein expression in the liver ...

journal_title：Journal of medical virology

authors： Wakita T,Katsume A,Kato J,Taya C,Yonekawa H,Kanegae Y,Saito I,Hayashi Y,Koike M,Miyamoto M,Hiasa Y,Kohara M

更新日期：2000-11-01 00:00:00

abstract：:Human papillomavirus (HPV) is known to be the cause of almost all cervical cancers. The genotypes have been classified into high and low risk types according to their oncogenic potential. However, data for many of the genotypes are limited and some (HPV-26, 53, and 66) have no agreed status. A study was undertaken to ...

journal_title：Journal of medical virology

authors： Brestovac B,Harnett GB,Smith DW,Shellam GR,Frost FA

更新日期：2005-05-01 00:00:00

abstract：:During 2002, an upsurge in frequency of hepatitis A outbreaks among injecting drug users was observed in England and Wales. As lack of risk factor information and the high mobility of the cases made linkage of outbreaks difficult, the relationship of nucleotide sequences in the VP1/2PA junction of the hepatitis A viru...

journal_title：Journal of medical virology

authors： Ngui SL,Granerod J,Jewes LA,Crowcroft NS,Teo CG,2002 Hepatitis A Outbreaks Investigation Network.

更新日期：2008-07-01 00:00:00

abstract：:Latency associated peptide (LAP) is a protein expressed on the membrane of some regulatory T cells (Treg). LAP+ Treg have a greater immunomodulatory effect than that of their negative counterparts. In this study, we presented the data on the proportion of LAP+ Treg out of CD4+ cells in mice with viral myocarditis, whi...

journal_title：Journal of medical virology

authors： Wang X,Ge J,Chen R

更新日期：2019-05-01 00:00:00

abstract：:A small percentage of renal patients become infected with the BK polyomavirus (BKV), a pathogenic virus that causes BKV-associated nephropathy (BKVN), after kidney transplantation. This study presents a simple, rapid, high-throughput method for BKV genotyping using high-resolution melt analysis (HRMA). Using this nove...

journal_title：Journal of medical virology

authors： Matsuda Y,Qazi Y,Iwaki Y

更新日期：2011-12-01 00:00:00

abstract：:A pandemic of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection broke out all over the world; however, epidemiological data and viral shedding in pediatric patients are limited. We conducted a retrospective, multicenter study, and followed-up with all children from the families with SARS-CoV-2 inf...

journal_title：Journal of medical virology

authors： Hua CZ,Miao ZP,Zheng JS,Huang Q,Sun QF,Lu HP,Su FF,Wang WH,Huang LP,Chen DQ,Xu ZW,Ji LD,Zhang HP,Yang XW,Li MH,Mao YY,Ying MZ,Ye S,Shu Q,Chen EF,Liang JF,Wang W,Chen ZM,Li W,Fu JF

更新日期：2020-11-01 00:00:00

abstract：:In the ongoing coronavirus disease 2019 (COVID-19) pandemic, one potential cause of concern is that some discharged COVID-19 patients are testing positive again for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA. To better understand what is happening and to provide public health policy planners and ...

journal_title：Journal of medical virology

authors： Han Z,Battaglia F,Terlecky SR

更新日期：2020-07-01 00:00:00

abstract：:Studies of hepatitis B virus (HBV) infection in non-human primates such as chimpanzees are no longer possible due to ethical considerations and the endangered status of chimpanzees since April 2007 in Japan. A human hepatocyte transplanted chimeric mouse was used to characterize HBV infectivity in serial stages of acu...

journal_title：Journal of medical virology

authors： Tabuchi A,Tanaka J,Katayama K,Mizui M,Matsukura H,Yugi H,Shimada T,Miyakawa Y,Yoshizawa H

更新日期：2008-12-01 00:00:00

abstract：:Hepatitis C virus (HCV) genotypes help to tailor the treatment response, but their influence on the disease severity and association with hepatic steatosis is not well understood. The prevalence of HCV genotypes and their correlation with the histopathological severity of liver disease and steatosis in Indian patients...

journal_title：Journal of medical virology

authors： Hissar SS,Goyal A,Kumar M,Pandey C,Suneetha PV,Sood A,Midha V,Sakhuja P,Malhotra V,Sarin SK

更新日期：2006-04-01 00:00:00

abstract：:A metagenomic approach based on target independent next-generation sequencing has become a known method for the detection of both known and novel viruses in clinical samples. This study aimed to use the metagenomic sequencing approach to characterize the viral diversity in respiratory samples from patients with respir...

journal_title：Journal of medical virology

authors： Madi N,Al-Nakib W,Mustafa AS,Habibi N

更新日期：2018-03-01 00:00:00

abstract：:Enteroviruses are responsible for hand, foot, and mouth disease, and have caused many deaths in China during recent years. But the natural history of enterovirus infection in children, especially asymptomatic children, is not yet clear. From April 2011 to May 2012, 505 stool and throat swab samples of children attendi...

journal_title：Journal of medical virology

authors： Cai J,Lv H,Lin J,Chen Z,Fang C,Han J

更新日期：2014-09-01 00:00:00

abstract：:The epidemiology of HTLV-I infection in female prostitutes was studied in a survey of 395 prostitutes from Callao, Peru (the port city of Lima), 72 prostitutes from Iquitos, Peru (another port city on the Amazon River), and 510 prenatal clinic patients from Lima. Prostitutes reported a mean of 8.8 years (range, 1-39 y...

journal_title：Journal of medical virology

authors： Wignall FS,Hyams KC,Phillips IA,Escamilla J,Tejada A,Li O,Lopez F,Chauca G,Sanchez S,Roberts CR

更新日期：1992-09-01 00:00:00

abstract：:Sera from 79 patients with acute self-limiting hepatitis, 17 patients with acute hepatitis B evolving into chronic HBsAg carriership, and 43 chronic HBsAg carriers without a history of acute hepatitis were analyzed for presence of hepatitis B virus (HBV)-DNA by a molecular hybridization technique. In acute self-limiti...

journal_title：Journal of medical virology

authors： Moestrup T,Hansson BG,Widell A,Blomberg J,Nordenfelt E

更新日期：1985-12-01 00:00:00

abstract：:Major differences exist between HIV-1 and HIV-2 in terms of epidemiology, pathogenicity, sensitivity to antiretrovirals. Determining the type of HIV infecting a patient is essential for management. The aim of this study was to evaluate the ability of simple/rapid tests to differentiate between HIV-1 and/or HIV-2 infec...

journal_title：Journal of medical virology

authors： Gautheret-Dejean A,Bocobza J,Brunet S,Damond F,Plantier JC,Barin F

更新日期：2015-12-01 00:00:00

abstract：:Variation at the IL-28B locus was recently reported to be a significant predictive factor of viral response to pegylated-interferon plus ribavirin combination therapy against chronic hepatitis C. Predictive factors for the effect of therapy, including IL-28B polymorphism rs8099917 and viral and clinical factors were i...

journal_title：Journal of medical virology

authors： Hashimoto Y,Ochi H,Abe H,Hayashida Y,Tsuge M,Mitsui F,Hiraga N,Imamura M,Takahashi S,Nelson Hayes C,Ohishi W,Kubo M,Tsunoda T,Kamatani N,Nakamura Y,Chayama K

更新日期：2011-06-01 00:00:00

abstract：:An attempt was made to identify factors influencing the cumulative probability of an increased alanine aminotransferase (ALT) level and hepatocarcinogenesis in hepatitis C patients with a normal ALT level initially. A total of 398 consecutive patients with a normal ALT level initially for 6 months or more and follow-u...

journal_title：Journal of medical virology

authors： Kumada T,Toyoda H,Kiriyama S,Sone Y,Tanikawa M,Hisanaga Y,Kanamori A,Atsumi H,Takagi M,Nakano S,Arakawa T,Fujimori M

更新日期：2009-03-01 00:00:00

abstract：:Increased expression of inducible nitric oxide synthase (iNOS) has been found in inflammatory myocardial disease and increased production of nitric oxide (NO) has both an inhibitory effect on virus replication and a cytotoxic effect on host cells. To investigate the relationship between severity of enteroviral myocard...

journal_title：Journal of medical virology

authors： Bevan AL,Zhang H,Li Y,Archard LC

更新日期：2001-06-01 00:00:00

abstract：:Hepatitis A virus (HAV) is the leading cause of acute viral hepatitis worldwide, with HAV infection being restricted to humans and nonhuman primates. In this study, HAV infection status was serologically determined in domestic pigs and experimental infections of HAV were attempted to verify HAV infectivity in pigs. An...

journal_title：Journal of medical virology

authors： Song YJ,Park WJ,Park BJ,Kwak SW,Kim YH,Lee JB,Park SY,Song CS,Lee SW,Seo KH,Kang YS,Park CK,Song JY,Choi IS

更新日期：2016-04-01 00:00:00

abstract：:We developed approaches using antisense RNA to inhibit hepatitis C virus (HCV) RNA translation and HCV core protein expression. An HCV genotype 1b cDNA comprising nt 1-1321 or a fusion construct consisting of HCV (nt 1-584) and luciferase cDNAs were inserted downstream of T7 and CMV promoter sequences and used to gene...

journal_title：Journal of medical virology

authors： Wakita T,Moradpour D,Tokushihge K,Wands JR

更新日期：1999-03-01 00:00:00

abstract：:This was an exploratory study to investigate lamivudine-resistant hepatitis B virus (HBV) strains in selected lamivudine-naïve HBV carriers with and without human immunodeficiency virus (HIV) co-infection in South African patients. Thirty-five lamivudine-naïve HBV infected patients with or without HIV co-infection wer...

journal_title：Journal of medical virology

authors： Selabe SG,Lukhwareni A,Song E,Leeuw YG,Burnett RJ,Mphahlele MJ

更新日期：2007-11-01 00:00:00

abstract：:During 2002, several epidemics of aseptic meningitis were attributed to echovirus 13 in Korea. The causative agents of these outbreaks were isolated and identified using rhabdosarcoma cells, HEp-2 and Buffalo green monkey kidney cells, and a neutralization test using monospecific antiserum. Fifty-four echovirus 13 iso...

journal_title：Journal of medical virology

authors： Cheon DS,Lee J,Lee K,Lee S,Park K,Ahn J,Jee Y,Yoon J,Cho H

更新日期：2004-07-01 00:00:00