Abstract:
:Latency associated peptide (LAP) is a protein expressed on the membrane of some regulatory T cells (Treg). LAP+ Treg have a greater immunomodulatory effect than that of their negative counterparts. In this study, we presented the data on the proportion of LAP+ Treg out of CD4+ cells in mice with viral myocarditis, which we believed was more sensitive and specific than that of the ratio of total Treg in CD4+ cells. Comparing with the previously recognized total Treg, LAP+ Treg was a better biomarker on myocardial inflammation.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Wang X,Ge J,Chen Rdoi
10.1002/jmv.25378subject
Has Abstractpub_date
2019-05-01 00:00:00pages
886-889issue
5eissn
0146-6615issn
1096-9071journal_volume
91pub_type
杂志文章abstract::An enzyme-linked immunosorbent assay (ELISA) using recombinant nucleoprotein (rNP) was reported for the detection of immunoglobulin G (IgG) antibodies to Crimean-Congo hemorrhagic fever (CCHF) virus (CCHFV). The immunoglobulin M (IgM)-capture ELISA was developed for the diagnosis of CCHFV infections, using CCHFV rNP a...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20270
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abstract::A small percentage of renal patients become infected with the BK polyomavirus (BKV), a pathogenic virus that causes BKV-associated nephropathy (BKVN), after kidney transplantation. This study presents a simple, rapid, high-throughput method for BKV genotyping using high-resolution melt analysis (HRMA). Using this nove...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22239
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abstract::Three hepatitis B surface antigen (HBsAg) preparations were compared: purified intact 22-nm HBsAg particles; HBsAg-derived, sodium dodecyl sulfate (SDS)-denatured P25 + GP30 polypeptide pool; and nondenatured P25 + GP30 micelles. The micelles had the same polypeptide composition as the P25 + GP30 pool. The immunogenic...
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21201
更新日期:2008-07-01 00:00:00
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journal_title:Journal of medical virology
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更新日期:2008-01-01 00:00:00
abstract::Intramuscular (IM) influenza vaccines are about 50% effective in preventing clinical illness among the elderly and their effectiveness in eliciting mucosal response may be even lower. The aim of the present study was to evaluate the immunological effect of a novel inactivated intranasal (IN) trivalent whole influenza ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:2000-05-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:2012-08-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890160210
更新日期:1985-06-01 00:00:00
abstract:BACKGROUND:Acute respiratory infection (ARI) is a leading cause of morbidity and mortality in children in low and middle-income countries. Human metapneumovirus (hMPV) is one of the most common viral etiological agents for ARIs in children. OBJECTIVES:In this study, we explored the genotypic diversity and the epidemio...
journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:2019-04-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.10076
更新日期:2002-07-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24648
更新日期:2017-03-01 00:00:00
abstract::It have been suggested that hepatitis B virus (HBV) pre-S deletions may play a role in hepatocarcinogenesis. The aim of the study was to determine the prevalence of pre-S deletions in chronic hepatitis B patients in Hong Kong, the factors associated with the deletions and its relationship with hepatitis B e antigen (H...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21901
更新日期:2010-11-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23449
更新日期:2013-02-01 00:00:00
abstract::Hemorrhagic fever with renal syndrome (HFRS) is a severe acute viral disease with pathological changes of impaired capillary and small vessels and thrombocytopenia. In this study, serum thrombospondin (TSP)-1 concentration in patients with HFRS was determined to explore its possible role in the pathogenesis of HFRS. T...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21270
更新日期:2008-10-01 00:00:00
abstract::Cervical cancer is the second most common cancer among Tunisian women, and the incidence rates vary by region. Three Tunisian registries report age-standardized rates of 6.3/10(5) in the central region, 5.4/10(5) in the north, and 2.7/10(5) in the south. High-risk human papillomavirus (HPV) types and their variants di...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22011
更新日期:2011-04-01 00:00:00
abstract::Epstein-Barr virus (EBV) DNA load in the blood increases in posttransplant lymphoproliferative disorders and chronic active EBV infection. In this report, we analyzed the EBV DNA load in the peripheral blood mononuclear cells (PBMCs) and plasma of patients with hydroa vacciniforme (HV) and/or hypersensitivity to mosqu...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.25811
更新日期:2020-04-07 00:00:00
abstract::The effect of antiviral treatment on apoptosis in chronic hepatitis B (CHB) has not been clarified. We evaluated the hepatic immunohistochemical expression of the pro-apoptotic bax and the antiapoptotic bcl-xL protein in HBeAg-negative CHB patients before and after treatment. In our study we included 72 paired biopsie...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21780
更新日期:2011-07-01 00:00:00
abstract::Genotype II.4 noroviruses (NoVs) are a leading cause of epidemic acute gastroenteritis in children and adults worldwide. The prevalence of different NoV genotypes causing outbreaks and sporadic cases of acute gastroenteritis in the region of Valencia, Spain, during a 4-year period (2008-11) was investigated. NoVs were...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24112
更新日期:2015-04-01 00:00:00
abstract::Palatine tonsils have been observed to harbor several distinct respiratory and herpesviruses in separate studies. In this study, the presence of these viruses in palatine tonsils was comprehensively studied in both children and adults. A cross-sectional analysis of 181 patients (median age 22 years; range, 2.6-66) ope...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26245
更新日期:2020-06-30 00:00:00
abstract::Screening for high-risk human papillomavirus (HPV) types allows the detection of women at a high risk of cervical squamous carcinomas, thereby defining a subset of patients targeted for more intensive screening and follow-up. Thirty-four cervical biopsy specimens and isolated cells from cervical smears of normal women...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(SICI)1096-9071(199602)48:2<161::AID-JMV8>
更新日期:1996-02-01 00:00:00
abstract::Swabbing the surface of a genital lesion to obtain a sample for HPV DNA testing is less invasive than a biopsy, but may not represent HPV types present in the lesion tissue. The objective of this study was to examine the concordance of HPV types detected in swab and biopsy samples from 165 genital lesions from men age...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23635
更新日期:2013-09-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24721
更新日期:2017-06-01 00:00:00
abstract::Interferon alpha (IFN-alpha) therapy is currently the treatment of choice for chronic hepatitis C (HCV) infection, but it fails to achieve a sustained response in approximately 75% of those treated. The factors which determine whether or not an individual will respond to IFN-alpha are uncertain, although a number of p...
journal_title:Journal of medical virology
pub_type: 临床试验,杂志文章
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更新日期:1995-03-01 00:00:00
abstract::Human papillomavirus (HPV) detection is used for screening of cervical cancer and genotype-specific persistence has shown to be mandatory for dysplasia development. Aim of this study was to evaluate the clinical performance of HPV DNA Array for cervical intraepithelial neoplasia 2+ (CIN2+) lesion detection. HPV DNA A...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.25583
更新日期:2020-01-01 00:00:00
abstract::Limited data are available describing human papillomavirus (HPV) genotype distribution among females with cytological abnormalities in Switzerland. Cervical cell specimens obtained from 5,318 women were screened routinely by liquid-based Pap smear. All specimens with cellular abnormalities were analyzed subsequently f...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22126
更新日期:2011-08-01 00:00:00
abstract::The predictive value of two methods for measuring HIV RNA concentration in plasma was assessed in relation to CD4 lymphocyte counts during the asymptomatic period of infection. The design was a retrospective longitudinal case-control study for a mean period of 60 months involving 20 asymptomatic patients included in t...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:1998-01-01 00:00:00
abstract::Currently, data examining nationally representative prevalence and trends of HBV or HCV among specific subgroups of pregnant women in the US are unavailable. We conducted a cross-sectional analysis of hospitalizations for liveborn singleton deliveries from 1998 to 2011 using data from the Nationwide Inpatient Sample. ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24725
更新日期:2017-06-01 00:00:00
abstract::The effect of HHV-6 strain A infection on the expression of Epstein-Barr virus- (EBV-) encoded growth transformation-associated genes in two EBV-positive Burkitt lymphoma cell lines, Akata and P3HR-3, was investigated. The results indicate that HHV-6A upregulates the expression of the latent membrane protein LMP-1 in ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:1998-07-01 00:00:00
abstract::Norovirus (NoV) is a causative agent of gastroenteritis in children and adults worldwide. Although reverse transcription-polymerase chain reaction (RT-PCR) has been accepted as the standard method for diagnosis of NoV infection, it requires well-trained personnel and sophisticated equipments. Performance of a commerci...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21916
更新日期:2010-12-01 00:00:00
abstract::A sensitive and reproducible real-time PCR assay based on TaqMan technology was developed for the detection and quantitation of hepatitis B virus (HBV) DNA in serum, and compared with an "in-house" qualitative PCR assay. HBV DNA was measured in 125 serum samples from 76 hepatitis B patients, consisting of 22 patients ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.2027
更新日期:2001-10-01 00:00:00