LAP+ Treg is a better biomarker than total Treg in viral myocarditis.

Abstract:

:Latency associated peptide (LAP) is a protein expressed on the membrane of some regulatory T cells (Treg). LAP+ Treg have a greater immunomodulatory effect than that of their negative counterparts. In this study, we presented the data on the proportion of LAP+ Treg out of CD4+ cells in mice with viral myocarditis, which we believed was more sensitive and specific than that of the ratio of total Treg in CD4+ cells. Comparing with the previously recognized total Treg, LAP+ Treg was a better biomarker on myocardial inflammation.

journal_name

J Med Virol

authors

Wang X,Ge J,Chen R

doi

10.1002/jmv.25378

subject

Has Abstract

pub_date

2019-05-01 00:00:00

pages

886-889

issue

5

eissn

0146-6615

issn

1096-9071

journal_volume

91

pub_type

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