Human cytomegalovirus (HCMV)-specific T cell but not neutralizing or IgG binding antibody responses to glycoprotein complexes gB, gHgLgO, and pUL128L correlate with protection against high HCMV viral load reactivation in solid-organ transplant recipients.

abstract：:Human respiratory syncytial virus group A (RSV-A) was detected in symptomatic hospital attended children in Central Spain for a continuous time period, September 2010 to April 2015. In order to accurately describe the epidemiology of this virus, the genetic diversity of the complete G gene and the clinical manifestati...

journal_title：Journal of medical virology

authors： Calderón A,Pozo F,Calvo C,García-García M,González-Esguevillas M,Molinero M,Casas I

更新日期：2017-05-01 00:00:00

abstract：:Primary HIV-1 infections (PHI) with non-B subtypes are increasing in developed countries while transmission of HIV-1 harboring antiretroviral resistance-associated mutations (RAMs) remains a concern. This study assessed non-B HIV-1 subtypes and RAMs prevalence among patients with PHI in university hospitals of Marseil...

journal_title：Journal of medical virology

authors： Tamalet C,Tissot-Dupont H,Motte A,Tourrès C,Dhiver C,Ravaux I,Poizot-Martin I,Dieng T,Tomei C,Bregigeon S,Zaegel-Faucher O,Laroche H,Aherfi S,Mokhtari S,Chaudet H,Ménard A,Brouqui P,Stein A,Colson P

更新日期：2018-10-01 00:00:00

abstract：:Mutations of the precore region of hepatitis B virus (HBV) genome have been associated with fulminant and severe chronic hepatitis. However uncertainty remains about the clinical significance and transmissibility of these mutant strains. A point mutation assay (PMA) was developed to identify qualitatively and quantita...

journal_title：Journal of medical virology

authors： Hawkins AE,Gilson RJ,Beath SV,Boxall EH,Kelly DA,Tedder RS,Weller IV

更新日期：1994-09-01 00:00:00

abstract：:Herpes simplex virus can be quantitatively recovered from vaginal tampons suspended in tissue culture medium and stored over a wide range of temperatures. Because herpes simplex virus is stable for several days with refrigeration or after freezing, this method of culture of cervicovaginal virus lends itself to epidemi...

journal_title：Journal of medical virology

authors： Myers MG,Ekwo EE,Pitts AK

更新日期：1979-01-01 00:00:00

abstract：:Serial determinations of titers of binding antibodies to single stranded DNA were performed over a period of three years in 43 type B hepatitis patients with persisting HBsAg who had either developed chronic hepatitis or were asymptomatic carriers. Patients with histopathological diagnosis of chronic active or chronic...

journal_title：Journal of medical virology

authors： Villarejos VM,Serra J,Visoná KA,Eduarte CE

更新日期：1979-01-01 00:00:00

abstract：:Hepatitis A virus (HAV) is usually transmitted by an oral-fecal route and is prevalent not only in developing countries but also in developed countries. In the present study, the phylogenetic characterization of the VP1/2A junction region (321 nucleotides) of China HAV isolates was examined. Anti-HAV IgM-positive seru...

journal_title：Journal of medical virology

authors： Cao J,Bi S,Meng Q,Shen L,Zheng H,Zhang Y

更新日期：2011-07-01 00:00:00

abstract：:There are numerous ongoing studies assessing treatment options for preventing, treating, and managing complications of coronavirus disease-2019 disease. The objective of this study was to do a systematic review and critical appraisal of the ongoing clinical trials with an aim to provide insight into the various interv...

journal_title：Journal of medical virology

authors： Venkatesulu BP,Thoguluva Chandrasekar V,Giridhar P,V P,Patel HK,Manteuffel J

更新日期：2021-02-01 00:00:00

abstract：:The relative frequency and distribution of the VP4 (P) genotypes of 227 human rotavirus field strains were investigated in South Africa. The stool samples were collected between 1984-1993 from infants and young children with diarrhea at Ga-Rankuwa Hospital, Pretoria, South Africa. The RNA was extracted from stools, he...

journal_title：Journal of medical virology

authors： Mphahlele MJ,Steele AD

更新日期：1995-09-01 00:00:00

abstract：:The prevalence of picobirnaviruses (PBVs) in human stools was investigated by polyacrylamide gel electrophoresis (PAGE) analysis of 832 faecal specimens collected between 1982 and 1993 from patients in various clinical groups. Similar prevalences (9-13%) were detected in patients with or without gastroenteritis and th...

journal_title：Journal of medical virology

authors： Gallimore CI,Appleton H,Lewis D,Green J,Brown DW

更新日期：1995-02-01 00:00:00

abstract：:A quantitative polymerase chain reaction (PCR) assay for hepatitis C viral RNA (HCV-RNA) was used to monitor viraemia levels in six patients at multiple time points before, during, and after interferon therapy for chronic non-A, non-B hepatitis (NANBH). Prior to therapy, serum HCV-RNA was detected in all patients at a...

journal_title：Journal of medical virology

authors： Garson JA,Brillanti S,Ring C,Perini P,Miglioli M,Barbara L

更新日期：1992-07-01 00:00:00

abstract：:Hemorrhagic fever with renal syndrome (HFRS) is a severe acute viral disease with pathological changes of impaired capillary and small vessels and thrombocytopenia. In this study, serum thrombospondin (TSP)-1 concentration in patients with HFRS was determined to explore its possible role in the pathogenesis of HFRS. T...

journal_title：Journal of medical virology

authors： Liu Z,Zhao Q,Han Q,Gao M,Zhang N

更新日期：2008-10-01 00:00:00

abstract：:Norovirus is a major etiologic agent in worldwide outbreaks of gastroenteritis associated with food as well as person-to-person transmission. The ubiquitous nature of Norovirus necessitates simple and rapid detection methods with high accuracy and sensitivity. To this end, several investigators have evaluated the usef...

journal_title：Journal of medical virology

authors： Yoda T,Suzuki Y,Yamazaki K,Sakon N,Kanki M,Kase T,Takahashi K,Inoue K

更新日期：2009-12-01 00:00:00

abstract：:The reported positive rates of hepatitis B virus surface antigen (HBsAg) among Chinese blood donors generally do not include data from pre-donation rapid tests. The aim of this study was to estimate the prevalence of serologic markers for HBsAg and risk factors among blood donors from Chengdu, China. From April 2010 t...

journal_title：Journal of medical virology

authors： Zhong L,Xi G,Zhang L,Liu S,Wan L,Yu L,Zhou M,Zhang J,He Y

更新日期：2016-02-01 00:00:00

abstract：:Occult hepatitis C virus (HCV) infection is characterized by the presence of HCV RNA in the liver cells or peripheral blood mononuclear cells of the patients whose serum samples test negative for HCV RNA, with or without presence of HCV antibodies. The present study reviews the existing literature on the persistence o...

journal_title：Journal of medical virology

authors： Vidimliski PD,Nikolov I,Geshkovska NM,Dimovski A,Rostaing L,Sikole A

更新日期：2014-09-01 00:00:00

abstract：:The relationship between cytomegalovirus (CMV) infection and cardiac allograft rejection is controversial, some authors reporting a significant association, others not, on the basis of the results of conventional virological diagnosis by culture or serology. This problem was reinvestigated in 88 patients using a semi-...

journal_title：Journal of medical virology

authors： Fernando S,Booth J,Boriskin Y,Butcher P,Carrington D,Steel H,Tryhorn Y,Corbishley C,Keeling P,Murday A

更新日期：1994-04-01 00:00:00

abstract：:At present eight hepatitis B virus (HBV) genotypes have been characterized: A to H. The most common genotype in Northern Europe is genotype A. So far there is no record of the specific HBV genotype distribution in Iceland. Iceland has a small population whose homogeneity has changed due to increasing migration during ...

journal_title：Journal of medical virology

authors： Björnsdottir TB,Stanzeit B,Sällberg M,Löve A,Hultgren C

更新日期：2005-12-01 00:00:00

abstract：:Human T-cell lymphotropic virus (HTLV) seroindeterminate cases have been reported among blood donors (BD) and in at-risk populations worldwide, including Argentina. The objective of the present work was to study the presence of HTLV-I/II infection and its association to specific Western blot (WB) patterns among health...

journal_title：Journal of medical virology

authors： Berini CA,Eirin ME,Pando MA,Biglione MM

更新日期：2007-01-01 00:00:00

abstract：:A procedure is described for the detection of hepatitis C virus (HCV) RNA in blood by means of the polymerase chain reaction (PCR) in which the reverse transcription step and two rounds of amplification are carried out in a single tube. This results in fewer manipulations, reduced risk of contamination, and economy of...

journal_title：Journal of medical virology

authors： Lin HJ,Shi N,Mizokami M,Hollinger FB

更新日期：1992-11-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) play a central role in tumor invasion and metastasis. Increased expression of MMPs occurs during development of hepatocellular carcinoma (HCC) in humans following infection with hepatitis B virus (HBV). Woodchucks are used as an animal model for hepadnavirus-induced HCC. All woodchucks...

journal_title：Journal of medical virology

authors： Ochoa-Callejero L,Toshkov I,Menne S,Martínez A

更新日期：2013-07-01 00:00:00

abstract：:This retrospective study investigated and characterized the YMDD motif of the hepatitis B virus (HBV) reverse transcriptase (RT) gene, in sequential samples of 17 South African patients with chronic hepatitis B infection on lamivudine treatment. The profile of HBV genotypes as well as the genetic variability of pre-co...

journal_title：Journal of medical virology

authors： Selabe SG,Song E,Burnett RJ,Mphahlele MJ

更新日期：2009-06-01 00:00:00

abstract：:This investigation is in continuation with the earlier studies on diarrhea epidemic due to rotavirus, that occurred at Jawhar western India, among tribal children during Dec 2000-Jan 2001 published by National Institute of Virology, Pune. Three rotavirus strains were isolated in cell culture from fecal specimens of af...

journal_title：Journal of medical virology

authors： Awachat PS,Kelkar SD

更新日期：2005-09-01 00:00:00

abstract：:In order to determine whether peripheral blood mononuclear cells (PBMC) contain proviral DNA or double-stranded replicative forms of TT virus (TTV) and to define which cell subset harbors TTV, we analyzed 126 PBMC DNA samples by PCR, using the NG059/NG061/NG063 and the T801/T935 primer sets. TTV sequences were detecte...

journal_title：Journal of medical virology

authors： Yu Q,Shiramizu B,Nerurkar VR,Hu N,Shikuma CM,Melish ME,Cascio K,Imrie A,Lu Y,Yanagihara R

更新日期：2002-02-01 00:00:00

abstract：:A possible new subgroup of human rotavirus was found by crossed immunoelectrophoresis and enzyme-linked immunosorbent assay. The epidemiology of the established subgroups 1 and 2 and this new variant was studied in two different communities. Of 398 rotavirus isolates from Malmö, Sweden, 26.8% were of type 1, 71.7% of ...

journal_title：Journal of medical virology

authors： Tufvesson B

更新日期：1983-01-01 00:00:00

abstract：:To determine whether unconventional pathogens causing subacute spongiform encephalopathy may be present in blood products, a newly developed hepatitis B vaccine and a widely used blood product were injected into mice and rats. As only a few aged mice in the test and the control groups showed spongiform encephalopathic...

journal_title：Journal of medical virology

authors： Tateishi J,Tsuji S

更新日期：1985-05-01 00:00:00

abstract：:Replication of HIV-1 inside host cells is dependent on both viral and host factors. MicroRNAs are small noncoding RNAs that regulate protein synthesis. MicroRNAs may control viral replication either by directly targeting the viral genome or indirectly through cellular proteins that are required during the viral lifecy...

journal_title：Journal of medical virology

authors： Dubey RC,Alam NB,Gaur R

更新日期：2020-12-24 00:00:00

abstract：:The study characterized the virological patterns and the resistance-associated substitutions (RASs) in patients with failure to IFN-free regimens enrolled in the real-life setting. All 87 consecutive HCV patients with failed IFN-free regimens, observed at the laboratory of the University of Campania, were enrolled. Al...

journal_title：Journal of medical virology

authors： Starace M,Minichini C,De Pascalis S,Macera M,Occhiello L,Messina V,Sangiovanni V,Adinolfi LE,Claar E,Precone D,Stornaiuolo G,Stanzione M,Ascione T,Caroprese M,Zampino R,Parrilli G,Gentile I,Brancaccio G,Iovinella V,

更新日期：2018-05-01 00:00:00

abstract：:To investigate the genetic diversity, time origin, and evolutionary history of the 2019-nCoV outbreak in China and Thailand, a total of 12 genome sequences of the virus with known sampling date (24 December 2019 and 13 January 2020) and geographic location (primarily Wuhan city, Hubei Province, China, but also Bangkok...

journal_title：Journal of medical virology

authors： Li X,Zai J,Wang X,Li Y

更新日期：2020-04-01 00:00:00

abstract：INTRODUCTION:Although the effectiveness of direct-acting antivirals (DAAs) for the treatment of chronic hepatitis C virus (HCV) has been reported in real-world settings, predictive factors of treatment failure are lacking. Therefore, we sought to explore the baseline predictors of treatment response to DAAs. METHODS:T...

journal_title：Journal of medical virology

authors： Ridruejo E,Piñero F,Mendizabal M,Cheinquer H,Wolff FH,Anders M,Reggiardo V,Ameigeiras B,Palazzo A,Alonso C,Schinoni MI,Zuain MGV,Tanno F,Figueroa S,Santos L,Peralta M,Soza A,Vistarini C,Adrover R,Fernández N,Perez

更新日期：2020-08-04 00:00:00

abstract：:Although a T-cell response in human cytomegalovirus (HCMV)-immune individuals exists against the most abundantly expressed protein pp65 of the virus matrix, less is known about the determinants that evoke this response. The aim of the study was to identify regions within HCMV pp65 (ppUL83) that contain sequences for t...

journal_title：Journal of medical virology

authors： Khattab BA,Lindenmaier W,Frank R,Link H

更新日期：1997-05-01 00:00:00

abstract：:Interferon alpha (IFN-alpha) therapy is currently the treatment of choice for chronic hepatitis C (HCV) infection, but it fails to achieve a sustained response in approximately 75% of those treated. The factors which determine whether or not an individual will respond to IFN-alpha are uncertain, although a number of p...

journal_title：Journal of medical virology

authors： Garson JA,Brillanti S,Whitby K,Foli M,Deaville R,Masci C,Miglioli M,Barbara L

更新日期：1995-03-01 00:00:00