Three T-cell epitopes within the C-terminal 265 amino acids of the matrix protein pp65 of human cytomegalovirus recognized by human lymphocytes.

abstract：:The impact of dynamic respiratory syncytial virus (RSV) load on the clinical severity of hospitalized infants with bronchiolitis has not been clarified. Nasopharyngeal aspirates were obtained from 60 infants who were diagnosed with bronchiolitis within 96 hr of wheezing onset upon admission and on days 3, 5, and 7 in ...

journal_title：Journal of medical virology

authors： Zhou L,Xiao Q,Zhao Y,Huang A,Ren L,Liu E

更新日期：2015-08-01 00:00:00

abstract：:In total 1,525 blood serum samples were collected in October, 2013 in Russian Asia from people who reside in territories that are at high risk for emergence of influenza viruses with pandemic potential. Presence of antibodies to influenza viruses in the sera was tested in hemagglutination inhibition test. None of the ...

journal_title：Journal of medical virology

authors： Ilyicheva T,Abdurashitov M,Durymanov A,Susloparov I,Goncharova N,Kolosova N,Mikheev V,Ryzhikov A

更新日期：2016-01-01 00:00:00

abstract：:Recent studies have identified epithelial cell populations in human livers that are similar to the "oval cells" and "transitional cells" seen in rat livers during the early stages of chemical carcinogenesis. It has been suggested that these cells might be precursors of hepatocytes and theoretically could be involved i...

journal_title：Journal of medical virology

authors： Hsia CC,Thorgeirsson SS,Tabor E

更新日期：1994-07-01 00:00:00

abstract：:Hepatitis B virus (HBV) DNA may persist in the liver in the absence of serum HBV-DNA after a self-limited acute hepatitis B. This may also occur in patients with chronic hepatitis C virus (HCV) infection but its prevalence and its impact on liver histology is unknown. HBV-DNA was tested by polymerase chain reaction (P...

journal_title：Journal of medical virology

authors： Mariscal LF,Rodríguez-Iñigo E,Bartolomé J,Castillo I,Ortiz-Movilla N,Navacerrada C,Pardo M,Pérez-Mota A,Graus J,Carreño V

更新日期：2004-06-01 00:00:00

abstract：:Human herpesvirus 6 (HHV6) is a beta-herpesvirus capable of infecting several cell types from different origins. HHV6 is the etiological agent of exantem subitum and has been associated with several diseases, all characterized by an inflammatory response triggered by chemokines. We show that strain U1102 of HHV6 is ab...

journal_title：Journal of medical virology

authors： Caruso A,Favilli F,Rotola A,Comar M,Horejsh D,Alessandri G,Grassi M,Di Luca D,Fiorentini S

更新日期：2003-07-01 00:00:00

abstract：:As with hepatitis B vaccines, the recently developed hepatitis A vaccine is suitable not only for individual protection, but also for public health control measures. For introduction into routine immunisation programmes, however, hepatitis A vaccine should preferably be combined with other already established vaccines...

journal_title：Journal of medical virology

authors： Ambrosch F,Wiedermann G,André FE,Delem A,Gregor H,Hofmann H,D'Hondt E,Kundi M,Wynen J,Kunz C

更新日期：1994-12-01 00:00:00

abstract：:The JC virus (JCV) is a common human virus persisting in renal tissue. In immunocompromised individuals it may reactivate and cause progressive multifocal leukoencephalopathy (PML). JCV has also been implicated in cancerogenesis, leading to various brain tumors and cancers of gastrointestinal tract. In this study the ...

journal_title：Journal of medical virology

authors： Kmieciak D,Debicki S,Trzeciak WH

更新日期：2008-06-01 00:00:00

abstract：:Regulatory T cells (T(reg)) provide a balance to immune T cell activation thereby protecting the body from pathogen-induced immunopathology. Several persistent viruses induce T(reg) that subvert protective immune mechanisms and promote viral persistence. Epstein-Barr virus (EBV) generally infects children subclinicall...

journal_title：Journal of medical virology

authors： Wingate PJ,McAulay KA,Anthony IC,Crawford DH

更新日期：2009-05-01 00:00:00

abstract：:A rapid technique for the detection of hepatitis C virus (HCV) RNA in liver section using nonisotopic in situ hybridization was described. Only 3 of the 10 patients seropositive for antibody to HCV and HCV RNA had detectable HCV RNA in the hepatocytes (1%, 2%, and 15% of cells positive). No specific signal was detecte...

journal_title：Journal of medical virology

authors： Lau JY,Davis GL

更新日期：1994-03-01 00:00:00

abstract：:It has been reported that a new pattern of mutations, E44D/A and/or V118I, in the reverse transcriptase (RT) gene of HIV-1 confers a moderate level of resistance to lamivudine in the absence of the M184V mutation. The prevalence of this mutational pattern was studied in HIV-1 isolates obtained from 280 patients. These...

journal_title：Journal of medical virology

authors： Montes B,Segondy M

更新日期：2002-03-01 00:00:00

abstract：:Identification of high-risk HPV genotypes in patients is essential for vaccination and prevention programs while the geographic distribution of cervical cancer varies widely. HPV 16 is the major cause of cervical cancer followed by HPV 18, HPV 31, HPV 52, or HPV 58 depending on geographic area. In this study, the dist...

journal_title：Journal of medical virology

authors： Chansaenroj J,Junyangdikul P,Chinchai T,Swangvaree S,Karalak A,Gemma N,Poovorawan Y

更新日期：2014-04-01 00:00:00

abstract：:We developed an immunoperoxidase staining test to detect structural antigens of BK virus (BKV) in Vero cell cultures. This test was used to examine the neutralizing activity of human and immunized animal sera. It was shown that sera positive for BKV antibodies measured by hemagglutination inhibition test and enzyme-li...

journal_title：Journal of medical virology

authors： Flaegstad T,Traavik T,Christie KE,Joergensen J

更新日期：1986-07-01 00:00:00

abstract：:The purpose of this study was to determine whether autophagy regulates the expression of human cytomegalovirus (HCMV) immediately early two viral protein (IE2). Rapamycin and 3-methyladenine (3-MA) were used to stimulate or suppress autophagy during HCMV infection. UL122 recombinant plasmid was transfected to overexpr...

journal_title：Journal of medical virology

authors： Zhang X,Xi T,Zhang L,Bi Y,Huang Y,Lu Y,Liu X,Fang F

更新日期：2020-07-25 00:00:00

abstract：:The rapid emergence of coronavirus disease 2019 (COVID-19) has necessitated the implementation of diverse pandemic control strategies throughout the world. To effectively control the spread of this disease, it is essential that it be diagnosed at an early stage so that patients can be reliably quarantined such that di...

journal_title：Journal of medical virology

authors： Zheng Z,Yao Z,Wu K,Zheng J

更新日期：2020-11-01 00:00:00

abstract：:Citrullinated histone H3 (H3Cit) is the product of the conversion of peptidylarginine to citrulline in histone H3. We evaluated the H3Cit level in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) tissues and assessed its association with Beclin1 messenger RNA (mRNA) (a key autophagic regulator). The leve...

journal_title：Journal of medical virology

authors： Lu M,Zhang X,Xu Y,He G,Liu Q,Zhu J,Zhang C

更新日期：2020-08-01 00:00:00

abstract：:Coronavirus-like particle(s) (CVLP) are faecal-derived pleomorphic membrane bound virus-like particles characterised by a fringe of club-shaped spikes that measure about 27 nm in length. The association of CVLP with a variety of social, clinical, and epidemiological factors was examined after a 69 month survey of faec...

journal_title：Journal of medical virology

authors： Marshall JA,Thompson WL,Gust ID

更新日期：1989-12-01 00:00:00

abstract：:The expression levels of many genes change after treatment of human immunodeficiency virus (HIV)-infected subjects by antiretroviral drugs. High-throughput analysis of tremendous datasets led to the discovery of genes that are implicated in the treatment pathways. In this study, we performed a gene-enrichment analysis...

journal_title：Journal of medical virology

authors： Mozhgani SH,Zarei Ghobadi M,Behnam Rad M,Farzanehpour M,Behzadian F

更新日期：2019-12-01 00:00:00

abstract：:Seasonal fluctuations in hepatitis A have been observed in the Netherlands related to Turkish and Moroccan children after visiting their home countries. This study determined the prevalence and associated factors of hepatitis A virus (HAV) antibodies in Turkish and Moroccan children in Rotterdam. A random sample was t...

journal_title：Journal of medical virology

authors： Richardus JH,Vos D,Veldhuijzen IK,Groen J

更新日期：2004-02-01 00:00:00

abstract：:Variation at the IL-28B locus was recently reported to be a significant predictive factor of viral response to pegylated-interferon plus ribavirin combination therapy against chronic hepatitis C. Predictive factors for the effect of therapy, including IL-28B polymorphism rs8099917 and viral and clinical factors were i...

journal_title：Journal of medical virology

authors： Hashimoto Y,Ochi H,Abe H,Hayashida Y,Tsuge M,Mitsui F,Hiraga N,Imamura M,Takahashi S,Nelson Hayes C,Ohishi W,Kubo M,Tsunoda T,Kamatani N,Nakamura Y,Chayama K

更新日期：2011-06-01 00:00:00

abstract：:Flavivirus infections are a serious healthcare concern in tropical and subtropical countries. Although well-established laboratory tests can provide early diagnosis of acute dengue or Zika infections, access to these tests is limited in developing countries, presenting an urgent need to develop simple, rapid, and robu...

journal_title：Journal of medical virology

authors： Bedin F,Boulet L,Voilin E,Theillet G,Rubens A,Rozand C

更新日期：2017-09-01 00:00:00

abstract：:The seroprevalence of viral hepatitis in healthcare workers has important public health implications. To assess the risk factors for the acquisition of viral hepatitis in an unvaccinated cohort from an hyperendemic region, 567 healthcare workers from a large hospital in the capital of the Republic of Yemen were interv...

journal_title：Journal of medical virology

authors： Shidrawi R,Ali Al-Huraibi M,Ahmad Al-Haimi M,Dayton R,Murray-Lyon IM

更新日期：2004-08-01 00:00:00

abstract：:We have attempted to reactivate human herpesvirus 6 (HHV-6) by infection with HHV-7 using childhood exanthem subitum patients in vitro. Peripheral blood mononuclear cells (PBMCs) were collected from children who had a history of exanthem subitum(ES) by HHV-6 and were infected by human herpesvirus 7 (HHV-7) in vitro. T...

journal_title：Journal of medical virology

authors： Tanaka-Taya K,Kondo T,Nakagawa N,Inagi R,Miyoshi H,Sunagawa T,Okada S,Yamanishi K

更新日期：2000-03-01 00:00:00

abstract：:Patients attending the genitourinary medicine clinic at Watford General Hospital, UK, were examined for clinical signs of genital herpes infection. Genital swabs were taken from 194 patients (126 female, 68 male) who presented with genital ulceration or symptoms which were suggestive of genital herpes infection. Swabs...

journal_title：Journal of medical virology

authors： Slomka MJ,Emery L,Munday PE,Moulsdale M,Brown DW

更新日期：1998-06-01 00:00:00

abstract：:Infection with the human papillomavirus (HPV) is responsible for 99.7% of cervical cancers, the second most prevalent neoplasia in women worldwide and the fifth leading cause of death by cancer in this population. In Chile, the incidence rate is 14.4 cases per 100,000 women per year and it is considered a significant ...

journal_title：Journal of medical virology

authors： Ili CG,Brebi P,López J,García P,Leal P,Suarez E,Roa JC

更新日期：2011-05-01 00:00:00

abstract：:The long-term efficacy of lamivudine therapy in patients with hepatitis B virus (HBV) infection is still not clear. In this study, 20 non-cirrhotic Japanese patients infected with HBV received lamivudine therapy for more than 1 year and were followed for a median period of 8.5 years (range, 6.7-8.7 years). The rates o...

journal_title：Journal of medical virology

authors： Akuta N,Suzuki F,Suzuki Y,Sezaki H,Hosaka T,Someya T,Kobayashi M,Saitoh S,Arase Y,Ikeda K,Kobayashi M,Kumada H

更新日期：2005-04-01 00:00:00

abstract：:The infection of enterovirus 71 (EV71) resulted in hand, foot, and mouth disease and may lead to severe nervous system damage and even fatalities. There are no effective drugs to treat the EV71 virus and it is crucial to find novel drugs against it. Polysaccharide isolated from Durvillaea antarctica green algae has an...

journal_title：Journal of medical virology

authors： Xu T,Li Y,Wu HL,Chen H,Wu H,Guo M,Zhao M,Wang C,Lin T,Lin Z,Chen D,Xiang W,Zhu B

更新日期：2020-11-24 00:00:00

abstract：:Varicella zoster virus (VZV) causes varicella (chickenpox), after which virus becomes latent in ganglia along the entire neuraxis. Virus reactivation produces zoster (shingles). Infectious VZV is found in vesicles of patients with zoster and varicella, but virus shed in the absence of disease has not been documented. ...

journal_title：Journal of medical virology

authors： Cohrs RJ,Mehta SK,Schmid DS,Gilden DH,Pierson DL

更新日期：2008-06-01 00:00:00

abstract：:Norovirus (NoV) is a major cause of nonbacterial acute gastroenteritis (AGE) outbreaks worldwide, with infections reported in semiclosed environments, particularly in hospitals and nursing homes. Astrovirus (HAstV) is prevalent worldwide, especially in developing countries. We aimed to determine the prevalence, spatia...

journal_title：Journal of medical virology

authors： Bitencurt ELR,Siqueira JAM,Medeiros TB,Bandeira RDS,de Souza Oliveira D,de Paula Souza E Guimarães RJ,da Silva Soares L,Macarenhas JDP,Teixeira DM,Silva RSU,Loureiro ECB,de Moraes Silva MC,da Silva LD,Gabbay YB

更新日期：2019-06-01 00:00:00

abstract：:Studies have shown that swine HEV (sHEV) and rabbit HEV (rHEV) can experimentally infect rabbits and swine, respectively. However, no published data have documented isolating sHEV strains from rabbits in natural environment so far. To clarify the possibility of natural cross-species transmission of sHEV to rabbits, th...

journal_title：Journal of medical virology

authors： Liu L,Wang L,Xia J,Zhang Y,Zeng H,Liu P,Zou Q,Wang L,Zhuang H

更新日期：2016-04-01 00:00:00

abstract：:An attempt was made to identify factors influencing the cumulative probability of an increased alanine aminotransferase (ALT) level and hepatocarcinogenesis in hepatitis C patients with a normal ALT level initially. A total of 398 consecutive patients with a normal ALT level initially for 6 months or more and follow-u...

journal_title：Journal of medical virology

authors： Kumada T,Toyoda H,Kiriyama S,Sone Y,Tanikawa M,Hisanaga Y,Kanamori A,Atsumi H,Takagi M,Nakano S,Arakawa T,Fujimori M

更新日期：2009-03-01 00:00:00