Genotyping of human papillomavirus in cervical intraepithelial neoplasia in a high-risk population.

Abstract:

:Infection with the human papillomavirus (HPV) is responsible for 99.7% of cervical cancers, the second most prevalent neoplasia in women worldwide and the fifth leading cause of death by cancer in this population. In Chile, the incidence rate is 14.4 cases per 100,000 women per year and it is considered a significant public health problem. The natural history of cervical cancer begins gradually from low-grade and high-grade squamous intraepithelial lesions to an invasive disease. In this study the frequency of HPV types was determined by HPV genotyping with reverse line blot hybridization in 200 cytobrushes of women with preneoplastic lesions in a high-risk population. HPV DNA was found in 89% of the lesions (83.3% of low-grade squamous intraepithelial lesions and 93.6% of high-grade squamous intraepithelial lesions). Multiple HPV infections were found in 14.4% and 15.5% of low- and high-grade lesions, respectively. HPV 16 was the most frequent genotype in single infections, followed by HPV 18. These results show that most of the preneoplastic lesions of the cervix (60%) were associated with HPV 16 and/or HPV 18, supporting the implementation of an HPV vaccination program in this high-risk population.

journal_name

J Med Virol

authors

Ili CG,Brebi P,López J,García P,Leal P,Suarez E,Roa JC

doi

10.1002/jmv.22057

subject

Has Abstract

pub_date

2011-05-01 00:00:00

pages

833-7

issue

5

eissn

0146-6615

issn

1096-9071

journal_volume

83

pub_type

杂志文章
  • Complete coding regions of the prototypes enterovirus B93 and C95: phylogenetic analyses of the P1 and P3 regions of EV-B and EV-C strains.

    abstract::Complete coding regions were sequenced for two new enterovirus genomes: EV-B93 previously identified by VP1 sequencing, derived from a child with acute flaccid paralysis in the Democratic Republic of Congo; and EV-C95 from a French soldier with acute gastroenteritis in Djibouti. The EV-B93 P1 had more than 30% nucleot...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24062

    authors: Junttila N,Lévêque N,Magnius LO,Kabue JP,Muyembe-Tamfum JJ,Maslin J,Lina B,Norder H

    更新日期:2015-03-01 00:00:00

  • Molecular Characterization of Non-Polio Enteroviruses Isolated from Acute Flaccid Paralysis Patients in Uganda.

    abstract::Enteroviruses (EVs) are RNA viruses that can cause many clinical syndromes including acute flaccid paralysis (AFP). Within the global polio laboratory network, EVs are categorized either as polioviruses or non-polio enteroviruses (NPEVs). Specific NPEVs have been described in polio-like residual paralytic events in AF...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26804

    authors: Tushabe P,Howard W,Bwogi J,Birungi M,Eliku JP,Kakooza P,Bukenya H,Namuwulya P,Gaizi J,Tibanagwa M,Kabaliisa T,Mulindwa J,Muhanguzi D,Suchard M,Gumede N,Bakamutumaho B

    更新日期:2021-01-17 00:00:00

  • Human papillomavirus genotypes and their association with cervical neoplasia in a cohort of Western Australian women.

    abstract::Human papillomavirus (HPV) is known to be the cause of almost all cervical cancers. The genotypes have been classified into high and low risk types according to their oncogenic potential. However, data for many of the genotypes are limited and some (HPV-26, 53, and 66) have no agreed status. A study was undertaken to ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20330

    authors: Brestovac B,Harnett GB,Smith DW,Shellam GR,Frost FA

    更新日期:2005-05-01 00:00:00

  • Impact of disease-modifying drugs on the severity of  COVID-19 infection in multiple sclerosis patients.

    abstract::Recent evidence suggested that neurological manifestations occur in patients with a severe form of coronavirus disease (COVID-19). On the basis of this issue, neurologists are very concerned about patients with neurological disorders, especially multiple sclerosis (MS), as consumers of immunosuppressive or immune-modu...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/jmv.26593

    authors: Rostami Mansoor S,Ghasemi-Kasman M

    更新日期:2020-10-12 00:00:00

  • Infection of a human retinal pigment epithelial cell line with human herpesvirus 6 variant A.

    abstract::A retinal pigment epithelial (RPE) cell line (K-1034) was examined for its susceptibility to human herpesvirus 6 variant A (HHV-6A). Exposure of K-1034 cells to HHV-6A induced the formation of multinucleated giant cells, which was suppressed by an inhibitor of viral DNA synthesis. In the giant cells, herpesvirus nucle...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Arao Y,Soushi S,Sato Y,Moriishi E,Ando Y,Yamada M,Padilla J,Uno F,Nii S,Kurata T

    更新日期:1997-10-01 00:00:00

  • Failure of influenza vaccination in the aged.

    abstract::A cohort of 127 nursing home residents aged 60-98 years were vaccinated during the winter of 1985-86 with the A-Chile 1/83 (C), A-Philippines 2/82 (P), and B-USSR (B) commercial influenza vaccines. Before vaccination 40%, 23%, and 69% were susceptible to influenza Ac, Ap, and B, respectively [hemagglutinin inhibition ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890250112

    authors: Keren G,Segev S,Morag A,Zakay-Rones Z,Barzilai A,Rubinstein E

    更新日期:1988-05-01 00:00:00

  • Clinical and economic burden of pre-emptive therapy of cytomegalovirus infection in hospitalized allogeneic hematopoietic cell transplant recipients.

    abstract::Cytomegalovirus (CMV) infection remains a major complication after allogeneic hematopoietic cell transplantation (allo-HCT). We conducted a retrospective study to determine the clinical and economic burden of pre-emptive therapy (PET) for CMV infection in 100 consecutive hospitalized adult CMV positive serostatus allo...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25574

    authors: El Haddad L,Ghantoji SS,Park AK,Batista MV,Schelfhout J,Hachem J,Lobo Y,Jiang Y,Rondon G,Champlin R,Chemaly RF

    更新日期:2020-01-01 00:00:00

  • Cytomegalovirus excretion after bone marrow transplantation cannot be predicted from the pre-transplant level of IgG antibodies.

    abstract::The relationship of pre-bone-marrow transplant recipient and donor cytomegalovirus (CMV) antibody level to post-transplant recipient CMV excretion was investigated. CMV excretion was found to be related to pre-transplant recipient serological status, but not to level of antibody. This therefore contrasts with herpes s...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890330409

    authors: Pillay D,Webster A,Lee D,Prentice HG,Griffiths PD

    更新日期:1991-04-01 00:00:00

  • Sequence-specific detection method for reverse transcription, loop-mediated isothermal amplification of HIV-1.

    abstract::HIV diagnosis at the point-of-care or in resource-limited settings poses considerable challenges due to time and cost limitations. Currently, nucleic acid-based tests are the only reliable method for diagnosing recent infections during the window period post-infection and pre-seroconversion, but these tests are only s...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21490

    authors: Curtis KA,Rudolph DL,Owen SM

    更新日期:2009-06-01 00:00:00

  • Active replication of human immunodeficiency virus type 1 by peripheral blood mononuclear cells following coincubation with herpes viruses.

    abstract::Patients with acquired immunodeficiency syndrome (AIDS) commonly suffer from opportunistic infections associated with members of the herpes virus family. To investigate whether certain of these other viruses might have an effect on the ability of the human immunodeficiency virus type 1 (HIV-1) to replicate, we coincub...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890290207

    authors: Tremblay M,Gornitsky M,Wainberg MA

    更新日期:1989-10-01 00:00:00

  • Three T-cell epitopes within the C-terminal 265 amino acids of the matrix protein pp65 of human cytomegalovirus recognized by human lymphocytes.

    abstract::Although a T-cell response in human cytomegalovirus (HCMV)-immune individuals exists against the most abundantly expressed protein pp65 of the virus matrix, less is known about the determinants that evoke this response. The aim of the study was to identify regions within HCMV pp65 (ppUL83) that contain sequences for t...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9071(199705)52:1<68::aid-jmv11>

    authors: Khattab BA,Lindenmaier W,Frank R,Link H

    更新日期:1997-05-01 00:00:00

  • Epidemiological features and viral shedding in children with SARS-CoV-2 infection.

    abstract::A pandemic of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection broke out all over the world; however, epidemiological data and viral shedding in pediatric patients are limited. We conducted a retrospective, multicenter study, and followed-up with all children from the families with SARS-CoV-2 inf...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/jmv.26180

    authors: Hua CZ,Miao ZP,Zheng JS,Huang Q,Sun QF,Lu HP,Su FF,Wang WH,Huang LP,Chen DQ,Xu ZW,Ji LD,Zhang HP,Yang XW,Li MH,Mao YY,Ying MZ,Ye S,Shu Q,Chen EF,Liang JF,Wang W,Chen ZM,Li W,Fu JF

    更新日期:2020-11-01 00:00:00

  • Preliminary characterization of murine cytomegaloviruses with insertional and deletional mutations in the M34 open reading frame.

    abstract::A viable virus could not be recovered from a mutant murine cytomegalovirus (MCMV) BAC in which the M34 ORF had been deleted (BACDeltaM34). In contrast, an M34 mutant virus (RcM34), in which the M34 ORF was interrupted by transposon insertion at nt 44,827 of the Smith MCMV BAC, was attenuated in replication both in tis...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21211

    authors: Baluchova K,Kirby M,Ahasan MM,Sweet C

    更新日期:2008-07-01 00:00:00

  • Genotype-specific effects on left ventricular function in parvovirus B19-positive patients with dilated cardiomyopathy.

    abstract::Genotype-specific effects of parvovirus B19 (B19V) infections on left ventricular function in patients with dilated cardiomyopathy (DCM) have not been investigated so far. In this prospective clinical study, the prevalences of B19V genotypes in endomyocardial biopsies from patients presenting with inflammatory heart d...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.22187

    authors: Ruppert V,Meyer T,Balbach A,Richter A,Müller HH,Maisch B,Pankuweit S,German Heart Failure Network.

    更新日期:2011-10-01 00:00:00

  • ITPA gene polymorphism (94C>A) effects on ribavirin-induced anemia during therapy in Egyptian patients with chronic hepatitis C.

    abstract::Inosine triphosphatase (ITPA) gene variants can protect against ribavirin (RBV)-induced anemia in patients treated for chronic hepatitis C. The aim of this study was to determine the relationship between genetic variants of ITPA polymorphism, anemia, RBV dose reduction, and treatment response in hepatitis C virus (HCV...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24844

    authors: El Raziky M,Zayed NA,Abdel Baki A,Mansour SA,Shahin RMH

    更新日期:2017-10-01 00:00:00

  • Genetic variability of respiratory syncytial virus A in hospitalized children in the last five consecutive winter seasons in Central Spain.

    abstract::Human respiratory syncytial virus group A (RSV-A) was detected in symptomatic hospital attended children in Central Spain for a continuous time period, September 2010 to April 2015. In order to accurately describe the epidemiology of this virus, the genetic diversity of the complete G gene and the clinical manifestati...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24703

    authors: Calderón A,Pozo F,Calvo C,García-García M,González-Esguevillas M,Molinero M,Casas I

    更新日期:2017-05-01 00:00:00

  • Emergence of G3 and G9 rotavirus and increased incidence of mixed infections in the southern region of Ireland 2001-2004.

    abstract::Two hundred and thirty fecal specimens were collected from children (up to 5 years of age) admitted with suspected rotaviral gastroenteritis at four Irish hospitals (Cork University Hospital, Mercy Hospital, Cork, Waterford Regional Hospital, and Kerry General Hospital) in the southern region of Ireland, between 2001 ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20494

    authors: Reidy N,O'Halloran F,Fanning S,Cryan B,O'Shea H

    更新日期:2005-12-01 00:00:00

  • Tula and Puumala hantavirus NSs ORFs are functional and the products inhibit activation of the interferon-beta promoter.

    abstract::The S RNA genome segment of hantaviruses carried by Arvicolinae and Sigmodontinae rodents encodes the nucleocapsid (N) protein and has an overlapping (+1) open reading frame (ORF) for a putative nonstructural protein (NSs). The aim of this study was to determine whether the ORF is functional. A protein corresponding t...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20948

    authors: Jääskeläinen KM,Kaukinen P,Minskaya ES,Plyusnina A,Vapalahti O,Elliott RM,Weber F,Vaheri A,Plyusnin A

    更新日期:2007-10-01 00:00:00

  • Genetic characterization of measles viruses that circulated in Thailand from 1998 to 2008.

    abstract::During the period between 1998 and 2008, 48 representative measles viruses (MeVs) circulating in Thailand were subjected to genetic characterization. Three genotypes, G2, D5, and D9 were detected. The results suggested that measles genotype D5, which has been circulating since at least 1998, is the endemic genotype in...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23249

    authors: Pattamadilok S,Incomserb P,Primsirikunawut A,Lukebua A,Rota PA,Sawanpanyalert P

    更新日期:2012-05-01 00:00:00

  • Development and validation of a new serum standard for the measurement of anti-HEV antibodies in animals.

    abstract::Although hepatitis E virus (HEV) infection is a zoonosis, there is, currently, no standardized assay for quantitatively measuring anti-HEV antibody levels in HEV animal reservoirs. In this study, anti-HEV antibody positive serum from a rabbit (RS26) was calibrated by dose-response parallel line assay using the World H...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24651

    authors: Zhang Y,Wang L,Zeng H,Gong W,Wang L,Zhuang H

    更新日期:2017-03-01 00:00:00

  • The effect of EBV on WIF1, NLK, and APC gene methylation and expression in gastric carcinoma and nasopharyngeal cancer.

    abstract::Epstein-Barr virus (EBV) is an important DNA tumor virus that is associated with approximately 10% of gastric carcinomas and 99% of nasopharyngeal cancers (NPC). DNA methylation and microRNAs (miRNAs) are the most studied epigenetic mechanisms that can prompt disease susceptibility. This study aimed to detect the effe...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24863

    authors: Zhao Z,Liu W,Liu J,Wang J,Luo B

    更新日期:2017-10-01 00:00:00

  • Recent trends in hepatitis A incidence in Brazil.

    abstract::Hepatitis A incidence has been decreasing in Brazil since child vaccination was implemented in 2014. This trend was interrupted by an outbreak among adult male in São Paulo in 2017. This study was outlined to estimate whether the increase of hepatitis A cases among adult men in Brazil was restricted to São Paulo. Case...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25694

    authors: De Oliveira TM,Vieira NSG,Sepp TDS,Souto FJD

    更新日期:2020-08-01 00:00:00

  • Analyzing the epidemiological outbreak of COVID-19: A visual exploratory data analysis approach.

    abstract::There is an obvious concern globally regarding the fact about the emerging coronavirus 2019 novel coronavirus (2019-nCoV) as a worldwide public health threat. As the outbreak of COVID-19 causes by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) progresses within China and beyond, rapidly available epi...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25743

    authors: Dey SK,Rahman MM,Siddiqi UR,Howlader A

    更新日期:2020-06-01 00:00:00

  • Hepatitis B virus markers in anti-HBc only positive individuals.

    abstract::Isolated reactivity to hepatitis B virus (HBV) core antigen (anti-HBc) is observed relatively frequently in immunocompromised individuals, intravenous drug abusers (IVDA), and in the presence of HCV infection. The reason for the lack of HBsAg is not clear. The aim of the present study was to investigate which factors ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1052

    authors: Weber B,Melchior W,Gehrke R,Doerr HW,Berger A,Rabenau H

    更新日期:2001-07-01 00:00:00

  • Norovirus infections and seroprevalence of genotype GII.4-specific antibodies in a Spanish population.

    abstract::Genotype II.4 noroviruses (NoVs) are a leading cause of epidemic acute gastroenteritis in children and adults worldwide. The prevalence of different NoV genotypes causing outbreaks and sporadic cases of acute gastroenteritis in the region of Valencia, Spain, during a 4-year period (2008-11) was investigated. NoVs were...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24112

    authors: Carmona-Vicente N,Fernández-Jiménez M,Ribes JM,Téllez-Castillo CJ,Khodayar-Pardo P,Rodríguez-Diaz J,Buesa J

    更新日期:2015-04-01 00:00:00

  • Impact of COVID-19 preventative measures on dengue infections in Taiwan.

    abstract::We read with great interest the recent issue,1 which raised the concern about the co-circulation of dengue during the COVID-19 pandemic. This article is protected by copyright. All rights reserved. ...

    journal_title:Journal of medical virology

    pub_type: 信件

    doi:10.1002/jmv.26650

    authors: Lin SF,Lai CC,Chao CM,Tang HJ

    更新日期:2020-11-03 00:00:00

  • Gastroenterology manifestations and COVID-19 outcomes: A meta-analysis of 25,252 cohorts among the first and second waves.

    abstract:BACKGROUND AND AIM:A meta-analysis was performed to identify COVID-19 patients presenting with gastrointestinal (GI) symptoms during the first and second pandemic waves and investigate their association with the disease outcomes. METHODS:A systematic search in PubMed, Scopus, Web of Science, ScienceDirect, and EMBASE ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/jmv.26836

    authors: Elshazli RM,Kline A,Elgaml A,Aboutaleb MH,Salim MM,Omar M,Munshi R,Mankowski N,Hussein MH,Attia AS,Toraih EA,Settin A,Killackey M,Fawzy MS,Kandil E

    更新日期:2021-02-02 00:00:00

  • Total HCV core antigen assay: a new marker of hepatitis C viremia for monitoring the progress of therapy.

    abstract::The ability of the total hepatitis C virus (HCV) core antigen assay was evaluated for monitoring the therapeutic responses of HCV-infected patients treated with interferon. The ability to detect and quantitate an independent structural protein component of HCV, in the presence of circulating antibodies, makes this ass...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.10355

    authors: Zanetti AR,Romanò L,Brunetto M,Colombo M,Bellati G,Tackney C

    更新日期:2003-05-01 00:00:00

  • Switching to tenofovir disoproxil fumarate vs continuing treatment in patients with chronic hepatitis B who maintain long-term virological response to entecavir therapy: A randomized trial.

    abstract::No controlled trial in patients with chronic hepatitis B virus (HBV) infection on long-term entecavir (ETV) treatment, comparing switching to tenofovir disoproxil fumarate (TDF) with continuing the therapy, has been reported. Twenty-seven nucleos(t)ide-naïve patients with chronic HBV who underwent ETV therapy for ≥5 y...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/jmv.25442

    authors: Iida-Ueno A,Enomoto M,Kozuka R,Tamori A,Kawada N

    更新日期:2019-07-01 00:00:00

  • Prevalence of hepatitis B e antigen and its antibody as detected by radioimmunoassays.

    abstract::A solid-phase radioimmunoassay (RIA) for the detection of hepatitis B e antigen (HBeAg) and antibody (anti-HBe) was developed. The RIA was approximately 1,000-fold more sensitive than rheophoresis for HBeAg, and approximately 6,000-fold more sensitive than rheophoresis for anti-HBe. Generally, less than one-fifth of h...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890020202

    authors: Mushahwar IK,Overby LR,Frosner G,Deinhardt F,Ling CM

    更新日期:1978-01-01 00:00:00