Analyzing the epidemiological outbreak of COVID-19: A visual exploratory data analysis approach.

abstract：:The genotypic inhibitory quotient (GIQ) is the ratio between drug concentration and the number of resistance mutations. However, as different resistance scores can be calculated for the same protease inhibitor, the ability of a GIQ to predict the virological outcome may vary depending on the resistance score used as t...

journal_title：Journal of medical virology

authors： Gianotti N,Galli L,Danise A,Hasson H,Boeri E,Lazzarin A,Castagna A

更新日期：2006-12-01 00:00:00

abstract：:Alkali-dissociated, purified preparations of prototype coxsackievirus B4 release a protein kinase that catalyzes the incorporation of gamma-phosphate from 32P-labeled ATP into three virus capsid proteins (VP1, VP3, VP4), several additional proteins of the particle, and exogenous acceptor proteins. Using protamine sulf...

journal_title：Journal of medical virology

authors： Chatterjee NK,Nejman C

更新日期：1986-08-01 00:00:00

abstract：:Recently, it was demonstrated that the Varicella-zoster virus (VZV) infection led to an activation of MAP kinases. The viral protein encoded by ORF61 is a major effector of JNK/SAPK and p38/MAPK phosphorylation. ORF61 shows homology to HSV-1 ICP0, a multifunctional protein that influences the activity of c-Jun in infe...

journal_title：Journal of medical virology

authors： Rahaus M,Desloges N,Wolff MH

更新日期：2005-07-01 00:00:00

abstract：:Herpesviruses produce assembly proteins (AP) that act as scaffolding proteins for the assembly of the viral capsids. The products of the assemblin gene, which encodes both maturational protease and AP, have been established for herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (CMV). We cloned an inframe O...

journal_title：Journal of medical virology

authors： Garcia-Valcarcel M,Fowler WJ,Harper DR,Jeffries DJ,Layton GT

更新日期：1997-12-01 00:00:00

abstract：:Although neutralizing antibodies against Hantaan virus (HTV) can protect hosts from viral infection, T-cell responses to HTV are also important in host defense against HTV. However, much less is known about cytotoxic T lymphocyte (CTL) responses to HTV. To identify CTL epitopes in the HTV nucleocapsid protein (NP), we...

journal_title：Journal of medical virology

authors： Park JM,Cho SY,Hwang YK,Um SH,Kim WJ,Cheong HS,Byun SM

更新日期：2000-02-01 00:00:00

abstract：:A thirteen-year-old boy with bilateral orchitis was diagnosed as being infected by Coxsackie A9 virus by isolation of the virus from a throat swab and a fecal specimen. Serologic investigations revealed the development of transitory specific neutralizing IgM antibodies against the isotate and of persistent antibodies ...

journal_title：Journal of medical virology

authors： Willems WR,Hornig C,Bauer H,Klingmüller V

更新日期：1978-01-01 00:00:00

abstract：:Human herpesvirus 6 (HHV-6) and human immunodeficiency virus type 1 (HIV-1) may interact during transplacental transmission of HIV-1. The placental syncytiotrophoblast layer serves as the first line of defense of the fetus against viruses. Patterns of replication of HHV-6 variant A (HHV-6A) and HIV-1 were analyzed in ...

journal_title：Journal of medical virology

authors： Csoma E,Bácsi A,Liu X,Szabó J,Ebbesen P,Beck Z,Kónya J,Andirkó I,Nagy E,Tóth FD

更新日期：2002-05-01 00:00:00

abstract：:Little information is available on the impact of direct-acting antiviral (DAA) therapy on changes in liver fibrosis and steatosis. Liver stiffness (LS) and controlled attenuation parameter (CAP) values were evaluated using transient elastography. The study subjects were 214 elderly patients infected with HCV genotype ...

journal_title：Journal of medical virology

authors： Ogasawara N,Kobayashi M,Akuta N,Kominami Y,Fujiyama S,Kawamura Y,Sezaki H,Hosaka T,Suzuki F,Saitoh S,Suzuki Y,Arase Y,Ikeda K,Kobayashi M,Kumada H

更新日期：2018-02-01 00:00:00

abstract：:An outbreak of dengue type 2 occurred in North Queensland, Australia, between December 1996 and April 1997. Culture of serum in the Aedes albopictus C6/36 cell line with detection using immunofluorescent staining was compared with a culture-amplified detection system using an immunoperoxidase staining method in a micr...

journal_title：Journal of medical virology

authors： Gleeson F,McBride J,Norton R

更新日期：1999-02-01 00:00:00

abstract：:There are few data describing the comprehensive identification in and influence of newly identified respiratory viruses on asthma exacerbations. Most studies focus on inpatients. In this preliminary study, the point prevalence and the associations of picornavirus species described recently and human bocavirus (HBoV) w...

journal_title：Journal of medical virology

authors： Arden KE,Chang AB,Lambert SB,Nissen MD,Sloots TP,Mackay IM

更新日期：2010-08-01 00:00:00

abstract：:Individuals infected with HIV have higher circulating Epstein-Barr virus (EBV) DNA load compared to healthy carriers. This study investigated whether level of spontaneous immunoglobulin secreting cells, one of the major hallmarks of HIV infection, is associated with an increase of EBV DNA load in PBMCs and the spontan...

journal_title：Journal of medical virology

authors： Ouedraogo DE,Tuaillon E,Rubbo PA,Bollore K,Foulongne V,Reynes J,Vendrell JP

更新日期：2014-01-01 00:00:00

abstract：:Asymptomatic carriers have a major influence on the spreading of norovirus infections. The objective of this study was to examine the characteristics of patients and asymptomatic carriers affected by norovirus-related community gastroenteritis outbreaks. No significant difference between the two groups was observed in...

journal_title：Journal of medical virology

authors： Mori K,Konishi N,Suzuki Y,Harada S,Maeda M,Akase S,Obata H,Monma C,Nagano M,Kimoto K,Oda M,Somura Y,Hirai A,Shinkai T,Noda M,Sadamasu K

更新日期：2018-12-01 00:00:00

abstract：:Isolated reactivity to hepatitis B virus (HBV) core antigen (anti-HBc) is observed relatively frequently in immunocompromised individuals, intravenous drug abusers (IVDA), and in the presence of HCV infection. The reason for the lack of HBsAg is not clear. The aim of the present study was to investigate which factors ...

journal_title：Journal of medical virology

authors： Weber B,Melchior W,Gehrke R,Doerr HW,Berger A,Rabenau H

更新日期：2001-07-01 00:00:00

abstract：:Human parechoviruses (HPeV) are associated with central nervous system (CNS) infections and sepsis-like illnesses. However, data from China are not available. The aim of this study was to determine the prevalence, age, and seasonal distributions and genotypes of HPeV infections in children with CNS related disease in ...

journal_title：Journal of medical virology

authors： Zhong H,Lin Y,Su L,Cao L,Xu M,Xu J

更新日期：2013-02-01 00:00:00

abstract：:In a study in Kenya of corneal lesions occurring in children with measles virus infection, conjunctival lesions of a characteristic appearance were seen concomitant with the rash. The lesions became visible after staining by Lissamine green or Rose Bengal. In order to investigate whether these lesions were virus-induc...

journal_title：Journal of medical virology

authors： Nommensen FE,Dekkers NW

更新日期：1981-01-01 00:00:00

abstract：:Although many reports have already shown RSV outbreaks among hemato-oncology patients, genomic studies detecting similar RSV strains prior to an outbreak in the hospital are rare. In 2014, the University of the Ryukyus hospital hemato-oncology unit experienced, and successfully managed, a respiratory syncytial virus (...

journal_title：Journal of medical virology

authors： Nabeya D,Kinjo T,Parrott GL,Uehara A,Motooka D,Nakamura S,Nahar S,Nakachi S,Nakamatsu M,Maeshiro S,Haranaga S,Tateyama M,Tomoyose T,Masuzaki H,Horii T,Fujita J

更新日期：2017-08-01 00:00:00

abstract：:Chronic hepatitis B patients with low pre-treatment HBeAg (and HBV-DNA) levels are more likely to respond to interferon-alpha therapy. In retrospect, this low level of HBeAg may have been reached just before the start of therapy. Pre-treatment changes in HBeAg levels were studied in 121 patients undergoing interferon-...

journal_title：Journal of medical virology

authors： Heijtink RA,Janssen HL,Hop WC,Osterhaus AD,Schalm SW

更新日期：2001-03-01 00:00:00

abstract：:An enzyme-linked immunosorbent assay (ELISA) test using polyvalent antigens and antisera was used to detect Coxsackie B virus-specific IgM responses in 329 patients admitted to the Coronary Care Unit, Wellington Hospital, New Zealand over a 12-month period. The sera of 30 of 153 (19.6%) patients with acute myocardial ...

journal_title：Journal of medical virology

authors： Lau RC

更新日期：1986-02-01 00:00:00

abstract：:Persisting human papillomavirus (HPV) infection is a critical step in cervical carcinogenesis. This study was conducted to determine the type-specific HPV persistence and risk factors for persistence of high-risk HPV infections in a large cohort of Danish women. The study was based on a population-based prospective co...

journal_title：Journal of medical virology

authors： Nielsen A,Kjaer SK,Munk C,Osler M,Iftner T

更新日期：2010-04-01 00:00:00

abstract：:Influenza epidemic is an important cause of severe illness in the elderly. Age-dependent morbidity of influenza in the elderly is associated with weakened immunity. The baseline age-related memory T cell activity in Chinese persons who are exposed to influenza virus through natural infection, are associated with the p...

journal_title：Journal of medical virology

authors： Jia N,Li C,Liu YX,Richardus JH,Feng D,Yang H,Dang RL,Ma YH,Xu XN,Cao WC

更新日期：2009-08-01 00:00:00

abstract：:During Epstein-Barr virus (EBV) latency, the EBV genome is largely silenced by methylation. This silencing is overturned during the switch to the lytic cycle. A key event is the production of the viral protein Zta which binds to three Zta-response elements (ZRE) from the Rta promoter (Rp), two of which (ZRE2 and ZRE3)...

journal_title：Journal of medical virology

authors： Germi R,Guigue N,Lupo J,Semenova T,Grossi L,Vermeulen O,Epaulard O,de Fraipont F,Morand P

更新日期：2016-10-01 00:00:00

abstract：:The worldwide infection rate of herpesvirus is high, but the detailed prevalence in China, especially the central area, remains unclear. In the present study, the prevalence of herpes simplex virus (HSV), Epstein-Barr virus (EBV), and human cytomegalovirus (HCMV) was investigated in 303 healthy adults in Wuhan, a repr...

journal_title：Journal of medical virology

authors： Wen L,Qiu Y,Cheng S,Jiang X,Ma YP,Fang W,Wang W,Cui J,Ruan Q,Zhao F,Hu F,Luo MH

更新日期：2018-03-01 00:00:00

abstract：:SARS-CoV-2 infection is causing a pandemic disease that is reflected in challenging public health problems worldwide. Human leukocyte antigen (HLA)-based epitope prediction and its association with disease outcomes provide an important base for treatment design. A bioinformatic prediction of T cell epitopes and their ...

journal_title：Journal of medical virology

authors： Romero-López JP,Carnalla-Cortés M,Pacheco-Olvera DL,Ocampo-Godínez JM,Oliva-Ramírez J,Moreno-Manjón J,Bernal-Alferes B,López-Olmedo N,García-Latorre E,Domínguez-López ML,Reyes-Sandoval A,Jiménez-Zamudio L

更新日期：2020-09-28 00:00:00

abstract：:Studies of hepatitis B virus (HBV) infection in non-human primates such as chimpanzees are no longer possible due to ethical considerations and the endangered status of chimpanzees since April 2007 in Japan. A human hepatocyte transplanted chimeric mouse was used to characterize HBV infectivity in serial stages of acu...

journal_title：Journal of medical virology

authors： Tabuchi A,Tanaka J,Katayama K,Mizui M,Matsukura H,Yugi H,Shimada T,Miyakawa Y,Yoshizawa H

更新日期：2008-12-01 00:00:00

abstract：:It was reported previously food-borne transmission of hepatitis E virus (HEV) to humans from deer meat. The present study attempted to clarify whether eating uncooked deer meat is a major epidemiological risk factor for HEV infection in Kasai, a city in western Japan. In total, 45 volunteer subjects with experience of...

journal_title：Journal of medical virology

authors： Tei S,Kitajima N,Ohara S,Inoue Y,Miki M,Yamatani T,Yamabe H,Mishiro S,Kinoshita Y

更新日期：2004-09-01 00:00:00

abstract：:Sex differences in the predictors for hepatocellular carcinoma (HCC) development after direct-acting antiviral (DAA) therapy was investigated. DAA therapy was given to 1438 (663 male, 775 female) patients. Sex differences in the HCC development rate and the factors contributing to HCC development after DAA therapy wer...

journal_title：Journal of medical virology

authors： Watanabe T,Tokumoto Y,Joko K,Michitaka K,Horiike N,Tanaka Y,Tada F,Kisaka Y,Nakanishi S,Yamauchi K,Yukimoto A,Nakamura Y,Hirooka M,Abe M,Hiasa Y

更新日期：2020-05-06 00:00:00

abstract：:Despite a significant decrease in acute hepatitis A in the last 2 decades in Italy, outbreaks were observed occurring mostly in southern Italy. In this study, Bayesian phylogenetic analysis was used to analyze the origin of these epidemics. With this aim, 5 different data sets of hepatitis A virus sequences were built...

journal_title：Journal of medical virology

authors： Cella E,Riva E,Angeletti S,Fogolari M,Blasi A,Scolamacchia V,Spoto S,Bazzardi R,Lai A,Sagnelli C,Sagnelli E,Ciccozzi M

更新日期：2018-09-01 00:00:00

abstract：:Varicella zoster virus (VZV) causes varicella (chickenpox), after which virus becomes latent in ganglia along the entire neuraxis. Virus reactivation produces zoster (shingles). Infectious VZV is found in vesicles of patients with zoster and varicella, but virus shed in the absence of disease has not been documented. ...

journal_title：Journal of medical virology

authors： Cohrs RJ,Mehta SK,Schmid DS,Gilden DH,Pierson DL

更新日期：2008-06-01 00:00:00

abstract：:In total 1,525 blood serum samples were collected in October, 2013 in Russian Asia from people who reside in territories that are at high risk for emergence of influenza viruses with pandemic potential. Presence of antibodies to influenza viruses in the sera was tested in hemagglutination inhibition test. None of the ...

journal_title：Journal of medical virology

authors： Ilyicheva T,Abdurashitov M,Durymanov A,Susloparov I,Goncharova N,Kolosova N,Mikheev V,Ryzhikov A

更新日期：2016-01-01 00:00:00

abstract：:In order to assess the current seroepidemiology of hepatitis D virus (HDV) infection in Taiwan where hepatitis B virus (HBV) is hyperendemic, a total of 756 voluntary blood donors, 641 prostitutes, 1,014 patients with sexually transmitted diseases (STDs), and 628 drug abusers were studied. Radioimmunoassays were used ...

journal_title：Journal of medical virology

authors： Chen CJ,Tseng SF,Lu CF,Lin HC,You SL,Chen CS,Hwang SJ,Hsieh SF,Hsu ST

更新日期：1992-10-01 00:00:00