Protein kinase in nondiabetogenic coxsackievirus B4.

abstract：:To elucidate the role of host immune status in the evolution and complexity of hepatitis C virus (HCV) quasispecies, three chronic HCV-infected patients who underwent bone marrow transplantation (BMT) were studied. The three transplanted patients' sera were sampled at pre-BMT, 3 months after BMT, and 12 months after B...

journal_title：Journal of medical virology

authors： Ni YH,Chang MH,Chen PJ,Hsu HY,Lu TW,Lin KH,Lin DT

更新日期：1999-06-01 00:00:00

abstract：:Coronavirus-like particle(s) (CVLP) are faecal-derived pleomorphic membrane bound virus-like particles characterised by a fringe of club-shaped spikes that measure about 27 nm in length. The association of CVLP with a variety of social, clinical, and epidemiological factors was examined after a 69 month survey of faec...

journal_title：Journal of medical virology

authors： Marshall JA,Thompson WL,Gust ID

更新日期：1989-12-01 00:00:00

abstract：:Hepatitis C virus (HCV) exposure in blood donors is determined serologically by the detection of anti-HCV antibodies in serum or plasma. However, a "window" period of 30-70 days after exposure exists where specific antibodies to HCV antigens are not detected. The use of nucleic acid testing for the detection of HCV RN...

journal_title：Journal of medical virology

authors： Leary TP,Gutierrez RA,Muerhoff AS,Birkenmeyer LG,Desai SM,Dawson GJ

更新日期：2006-11-01 00:00:00

abstract：:Glycoproteins of enveloped viruses replicating in nonprimate mammalian cells carry α-1,3-galactose (α-Gal) glycans, and can bind to anti-Gal antibodies which are abundant in humans. The antibodies have protected humans and their ancestors for millions of years, because they inhibit replication of many kinds of microbe...

journal_title：Journal of medical virology

authors： Chen JM

更新日期：2020-07-18 00:00:00

abstract：:Hepatitis C virus (HCV) virions have been shown to be bound to antibodies in patients with chronic HCV infection. The sera from patients infected with genotype 1b HCV contained more antibody-free virions than those from patients with genotype 2a/2b HCV. When compared at the same levels of serum HCV RNA, free virion ti...

journal_title：Journal of medical virology

authors： Kimura Y,Hayashida K,Ishibashi H,Niho Y,Yanagi Y

更新日期：2000-05-01 00:00:00

abstract：:The prevalence of delta agent among 120 Chinese patients with HBsAg-positive chronic active and hepatocellular carcinoma from Taiwan and Los Angeles were studied by serological assay for antibody to delta antigen and immunoperoxidase staining for delta antigen in the liver biopsies. Of 120 patients, only four with chr...

journal_title：Journal of medical virology

authors： Govindarajan S,Lee SD,Tong MJ,Tsai YT,Lo KJ

更新日期：1984-01-01 00:00:00

abstract：:In countries with a low prevalence of human T-lymphotropic virus (HTLV) infection, indeterminate HTLV serologies are a major problem in blood bank screening because of the uncertainties about infection in these cases. The recent discovery of two new types of simian T-lymphotropic viruses (STLV), which give an HTLV-ind...

journal_title：Journal of medical virology

authors： Vandamme AM,Van Laethem K,Liu HF,Van Brussel M,Delaporte E,de Castro Costa CM,Fleischer C,Taylor G,Bertazzoni U,Desmyter J,Goubau P

更新日期：1997-05-01 00:00:00

abstract：:The genetic variability of hepatitis B virus (HBV) represents a challenge for the sensitivity of immunologic and molecular based assays. Genotyping studies show that the genetic diversity of HBV is very high even in industrialized countries. The analytical sensitivity of HBsAg and anti-HBs assays may be dependent on H...

journal_title：Journal of medical virology

authors： Weber B

更新日期：2006-01-01 00:00:00

abstract：:The molecular epidemiology of hepatitis A virus (HAV) strains circulating in the St. Petersburg and Karelia regions was studied during 1997-2003. Hepatitis A virus RNA was isolated from both clinical samples (stools or sera) and environmental samples (sewage water). RT-PCR was carried out using different primer pairs ...

journal_title：Journal of medical virology

authors： Davidkin I,Zheleznova N,Jokinen S,Gorchakova O,Broman M,Mukomolov S

更新日期：2007-06-01 00:00:00

abstract：:Human respiratory syncytial virus (HRSV) is major pathogen of lower respiratory tract infections in infants and young children worldwide. There have been many studies regarding HRSV subgroup A (HRSV-A) G protein genetic variability but little information about HRSV subtype B (HRSV-B) G protein genetic diversity and mo...

journal_title：Journal of medical virology

authors： Ren L,Xiao Q,Zhou L,Xia Q,Liu E

更新日期：2015-01-01 00:00:00

abstract：:The natural history of chronic hepatitis B virus (HBV) infection is highly variable, ranging from a benign course to one of shortened life expectancy. Liver histology represents an accurate tool for assessing progressive liver disease, and has been used in five recent Phase III clinical trials of the oral nucleoside a...

journal_title：Journal of medical virology

authors： Leung N

更新日期：2000-07-01 00:00:00

abstract：:Major differences exist between HIV-1 and HIV-2 in terms of epidemiology, pathogenicity, sensitivity to antiretrovirals. Determining the type of HIV infecting a patient is essential for management. The aim of this study was to evaluate the ability of simple/rapid tests to differentiate between HIV-1 and/or HIV-2 infec...

journal_title：Journal of medical virology

authors： Gautheret-Dejean A,Bocobza J,Brunet S,Damond F,Plantier JC,Barin F

更新日期：2015-12-01 00:00:00

abstract：:Men who have sex with men (MSM) are an important risk group for human immunodeficiency virus (HIV) and at high-risk of herpesvirus infection. However, limited information on epidemiologic patterns of HHV8 and HSV2 among MSM is available in mainland China. A cross-sectional study of 486 participants was performed in Sh...

journal_title：Journal of medical virology

authors： Liu Z,Fang Q,Zuo J,Wang J,Chen Y,Minhas V,Wood C,He N,Zhang T

更新日期：2017-05-01 00:00:00

abstract：:Co-infection with hepatitis delta virus (HDV) and hepatitis B virus (HBV) has been shown to be associated with a more severe form of acute and chronic hepatitis. Cloning and expression of recombinant HDV antigen (rHDAg) in Escherichiacoli are described. Using purified rHDAg, a cost-effective indirect anti-HDV enzyme-l...

journal_title：Journal of medical virology

authors： Shen L,Gu Y,Sun L,Yang Y,Wang F,Li Y,Bi S

更新日期：2012-03-01 00:00:00

abstract：:A total of 190 specimens from South Indian children aged 0-59 months with ocular anomalies consistent with suspected congenital rubella syndrome (CRS) were investigated. Twenty-six of the 65 infants (40%) were confirmed as CRS by detection of rubella specific IgM. Rubella RNA was detected in 41 samples from 26 infants...

journal_title：Journal of medical virology

authors： Rajasundari TA,Sundaresan P,Vijayalakshmi P,Brown DW,Jin L

更新日期：2008-03-01 00:00:00

abstract：:In vivo gene delivery using human adenovirus serotype 5 (AdV5) vectors is being explored for vaccination purposes. The presence of anti-AdV5 antibodies in human serum arising from natural exposure to AdV5 can interfere potentially with and compromise the efficacy of rAdV5-based vaccine vectors. In this report, a colle...

journal_title：Journal of medical virology

authors： Pilankatta R,Chawla T,Khanna N,Swaminathan S

更新日期：2010-03-01 00:00:00

abstract：:Lack of recognition of human immunodeficiency virus (HIV) infection especially in children and delayed implementation of effective control programs makes HIV infection as a major cause for concern. Information on HIV epidemiology in Iran as well as other Islamic countries is limited. The aim of our study was to descri...

journal_title：Journal of medical virology

authors： Movahedi Z,Mahmoudi S,Pourakbari B,Keshavarz Valian N,Sabouni F,Ramezani A,Bahador A,Mamishi S

更新日期：2016-01-01 00:00:00

abstract：:A novel coronavirus associated with acute respiratory disease (named SARS-CoV-2) is recently identified in Wuhan city, China, spread rapidly worldwide. Early identification of this novel coronavirus by molecular tools is critical for surveillance and control of the epidemic outbreak. We aimed to establish a simple met...

journal_title：Journal of medical virology

authors： Son HA,Hang DTT,Thuan ND,Quyen LTB,Thuong LTH,Nga VT,Quang LB,Hung TT,Son NT,Linh NT,Nam LV,Van Ba N,Tien TV,Quyet D,Van Luong H,Su HX

更新日期：2020-11-01 00:00:00

abstract：:Alignment of Crimean-Congo hemorrhagic fever virus (CCHFV) L genome segment full-length sequences reveals an overall high level of conservation among strains, with greater than 90% of translated amino acid residues strictly conserved. However, a region of marked variability identified previously, corresponding to L po...

journal_title：Journal of medical virology

authors： Meissner JD,Seregin SS,Seregin SV,Vyshemirskii OI,Samokhvalov EI,Lvov DK,Netesov SV,Petrov VS

更新日期：2006-02-01 00:00:00

abstract：:Dual infection with hepatitis B and C viruses is often encountered in endemic areas of both viruses. However, understanding of the clinical and virological implications is limited. The aim of this study was to investigate the role of each virus in liver injury and the interaction between the two viruses in dual infect...

journal_title：Journal of medical virology

authors： Ohkawa K,Hayashi N,Yuki N,Masuzawa M,Kato M,Yamamoto K,Hosotsubo H,Deguchi M,Katayama K,Kasahara A

更新日期：1995-07-01 00:00:00

abstract：:A comparative assessment of vidarabine and acyclovir in the treatment of varicella and disseminated zoster in immunosuppressed patients was undertaken. Thirty-eight immunosuppressed patients with varicella (N = 18) or disseminated zoster (N = 20) were treated intravenously with 10 mg/kg/day of vidarabine or 30 mg/kg/d...

journal_title：Journal of medical virology

authors： Vildé JL,Bricaire F,Leport C,Renaudie M,Brun-Vézinet F

更新日期：1986-10-01 00:00:00

abstract：:Ultra violet (UV) light-inactivated measles virus was used for the lymphocyte proliferation assay, where it caused consistently adult human peripheral blood monolymphocytes (PBML) proliferation which was not dependent on the measles virus complement fixation titre in the donor's sera. When the cord blood lymphocytes f...

journal_title：Journal of medical virology

authors： Tu R

更新日期：1995-06-01 00:00:00

abstract：:The incidence of noroviral gastroenteritis has increased dramatically in recent years, and norovirus (NoV) genogroup II.4 (GII.4) is associated with outbreaks worldwide. The NoV genotypes and their clinical relevance in children hospitalized with acute gastroenteritis between 2006 and 2011 in northern Taiwan were eval...

journal_title：Journal of medical virology

authors： Tsai CN,Lin CY,Lin CW,Shih KC,Chiu CH,Chen SY

更新日期：2014-02-01 00:00:00

abstract：:Interferon (IFN) alfa has been used widely for the treatment of chronic hepatitis C virus (HCV) infections but only a small number of patients treated have shown a sustained biochemical and virological response. Anti-envelope E1 and E2 antibody titers were assessed retrospectively before, during, and after treatment w...

journal_title：Journal of medical virology

authors： Depraetere S,Van Kerschaever E,Van Vlierberghe H,Elewaut A,Brouwer JT,Niesters HG,Schalm SW,Maertens G,Leroux-Roels G

更新日期：2000-02-01 00:00:00

abstract：:To investigate the intra-hepatic activation of the IFN system in patients affected by chronic HCV-infection in comparison with that observed in a non-infectious liver disease such as non-alcoholic steatohepatitis, we measured the liver steady state mRNA levels of interferon-alpha, interferon-beta and interferon-gamma ...

journal_title：Journal of medical virology

authors： Abbate I,Romano M,Longo R,Cappiello G,Lo Iacono O,Di Marco V,Paparella C,Spano A,Capobianchi MR

更新日期：2003-08-01 00:00:00

abstract：:Human immunodeficiency virus 2 (HIV-2) infection is characterized by a slower disease progression and lower transmission rates. The molecular features that could be assigned as directly involved in this in vivo phenotype remain essentially unknown, and the importance of HIV-2 as a model to understand pathogenicity of ...

journal_title：Journal of medical virology

authors： Santos-Costa Q,Parreira R,Moniz-Pereira J,Azevedo-Pereira JM

更新日期：2009-11-01 00:00:00

abstract：:Recent studies have suggested a pathogenic role of human parvovirus B19 (B19) in the development of acute fulminant liver failure in children. The hypothesis was based on the detection of B19 DNA in 8 of 10 explanted livers of children requiring liver transplantation. In the present study, explanted livers from 43 adu...

journal_title：Journal of medical virology

authors： Eis-Hübinger AM,Reber U,Abdul-Nour T,Glatzel U,Lauschke H,Pütz U

更新日期：2001-10-01 00:00:00

abstract：:The use of quantitative assays for hepatitis C virus specific antibodies (anti-HCV) as a prognostic marker was evaluated in 31 patients with chronic hepatitis C treated with interferon (IFN). Changes in titers of serum HCV-RNA and anti-HCV antibodies; anti-C11 (anti-core), anti-C100 (anti-NS3), and anti-C7 (anti-NS3) ...

journal_title：Journal of medical virology

authors： Urushihara A,Sodeyama T,Matsumoto A,Tanaka E

更新日期：1994-04-01 00:00:00

abstract：:A panel of deoxyoligonucleotide probes for studying the genetic variability and genotyping of Tick-borne encephalitis virus (TBEV) strains by molecular hybridization of nucleic acids (MHNA) was created. This panel allows to estimate the genetic structure of individual TBEV strains, as the targets for probes are both v...

journal_title：Journal of medical virology

authors： Demina TV,Dzhioev YP,Verkhozina MM,Kozlova IV,Tkachev SE,Plyusnin A,Doroshchenko EK,Lisak OV,Zlobin VI

更新日期：2010-05-01 00:00:00

abstract：:Patterns of endemicity of human herpesvirus 8 (HHV8) are still undefined in some European populations, such as those from Western Balkan countries. Serum samples from 605 human immunodeficiency virus-seronegative subjects (299 Albanians and 306 Kosovars) were tested for the presence of HHV8 antibodies to a capsid-rela...

journal_title：Journal of medical virology

authors： Chironna M,Tosatti MA,Di Gangi IM,Sallustio A,Germinario C,Coluzzi M,Quarto M,Chieco-Bianchi L,Calabrò ML

更新日期：2006-07-01 00:00:00