Current seroepidemiology of hepatitis D virus infection among hepatitis B surface antigen carriers of general and high-risk populations in Taiwan.

Abstract:

:In order to assess the current seroepidemiology of hepatitis D virus (HDV) infection in Taiwan where hepatitis B virus (HBV) is hyperendemic, a total of 756 voluntary blood donors, 641 prostitutes, 1,014 patients with sexually transmitted diseases (STDs), and 628 drug abusers were studied. Radioimmunoassays were used for testing HBV infection markers and antibody against HDV (anti-HDV) among HBsAg carriers. The anti-HDV prevalence among HBsAg carriers was significantly higher in STD patients (9.6%), prostitutes (33.1%), and drug abusers (68.1%) than in blood donors from the general population (2.2%). The prevalence gradually increased with age in blood donors and STD patients, but reached a plateau at a young age in prostitutes and drug abusers. Males had a higher prevalence than females in blood donors (2.7% vs. 0), STD patients (8.2% vs. 7.5%), and drug abusers (69.0% vs. 57.1%), but the difference was not statistically significant. STD patients with syphilis had a higher prevalence (19.5%) than those affected with non-ulcerating STDs (5.3%). While unlicensed prostitutes had a lower prevalence (13.6%) than licensed prostitutes (44.9%), intravenous drug abusers had a higher prevalence (73.1%) than non-intravenous drug abusers (34.6%). There was a twofold increase in anti-HDV prevalence from 1986 to 1989 among prostitutes, but the prevalence remained unchanged in the general population and drug abusers. HDV infection remains limited to the high-risk groups and spread mainly by promiscuity and needle sharing in Taiwan.

journal_name

J Med Virol

authors

Chen CJ,Tseng SF,Lu CF,Lin HC,You SL,Chen CS,Hwang SJ,Hsieh SF,Hsu ST

doi

10.1002/jmv.1890380205

keywords:

subject

Has Abstract

pub_date

1992-10-01 00:00:00

pages

97-101

issue

2

eissn

0146-6615

issn

1096-9071

journal_volume

38

pub_type

杂志文章
  • Development of a reverse transcription-polymerase chain reaction assay for diagnosis of lymphocytic choriomeningitis virus infection and its use in a prospective surveillance study.

    abstract::Lymphocytic choriomeningitis virus (LCMV), which is one of several arenaviruses that are pathogenic for humans, causes encephalitis and meningitis in man. In this study, single-stage and nested reverse transcription-polymerase chain reaction (RT-PCR) assays were developed that targeted the GPC and N genes of LCMV. Bot...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Park JY,Peters CJ,Rollin PE,Ksiazek TG,Gray B,Waites KB,Stephensen CB

    更新日期:1997-02-01 00:00:00

  • Long-term follow-up of hepatitis B virus and hepatitis C virus replicative levels in chronic hepatitis patients coinfected with both viruses.

    abstract::Dual infection with hepatitis B and C viruses is often encountered in endemic areas of both viruses. However, understanding of the clinical and virological implications is limited. The aim of this study was to investigate the role of each virus in liver injury and the interaction between the two viruses in dual infect...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890460316

    authors: Ohkawa K,Hayashi N,Yuki N,Masuzawa M,Kato M,Yamamoto K,Hosotsubo H,Deguchi M,Katayama K,Kasahara A

    更新日期:1995-07-01 00:00:00

  • Measles virus genotype B2 is not inactive: evidence of continued circulation in Africa.

    abstract::This study describes two measles outbreaks--one in Cape Town, South Africa in November 2002, and the other in Luanda, Angola in March 2003. The outbreaks were notable because they were caused by closely related genotype B2 viruses. This genotype was first described in an outbreak in Libreville, Gabon in the 1980s and ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20491

    authors: Smit SB,Hardie D,Tiemessen CT

    更新日期:2005-12-01 00:00:00

  • Dysregulation of the immune response affects the outcome of critical COVID-19 patients.

    abstract::Critical cases of coronavirus disease 2019 (COVID-19) are associated with a high risk of mortality. It remains unclear why patients with the same critical condition have different outcomes. We aimed to explore relevant factors that may affect the prognosis of critical COVID-19 patients. Six critical COVID-19 inpatient...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26181

    authors: Wei LL,Wang WJ,Chen DX,Xu B

    更新日期:2020-11-01 00:00:00

  • Molecular epidemiology of hepatitis A in St. Petersburg, Russia, 1997-2003.

    abstract::The molecular epidemiology of hepatitis A virus (HAV) strains circulating in the St. Petersburg and Karelia regions was studied during 1997-2003. Hepatitis A virus RNA was isolated from both clinical samples (stools or sera) and environmental samples (sewage water). RT-PCR was carried out using different primer pairs ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20843

    authors: Davidkin I,Zheleznova N,Jokinen S,Gorchakova O,Broman M,Mukomolov S

    更新日期:2007-06-01 00:00:00

  • Detection of human cytomegalovirus DNA in perilymph of patients with sensorineural hearing loss using real-time PCR.

    abstract::Although cytomegalovirus (CMV) has been detected in the inner ear fluid of patients who succumbed to the complications of symptomatic congenital CMV infection, it has not been detected in the inner ear fluid of living patients. In this study, real-time polymerase chain reaction (PCR) was used to measure CMV DNA in cli...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.10263

    authors: Sugiura S,Yoshikawa T,Nishiyama Y,Morishita Y,Sato E,Hattori T,Nakashima T

    更新日期:2003-01-01 00:00:00

  • A variable region in the Crimean-Congo hemorrhagic fever virus L segment distinguishes between strains isolated from different geographic regions.

    abstract::Alignment of Crimean-Congo hemorrhagic fever virus (CCHFV) L genome segment full-length sequences reveals an overall high level of conservation among strains, with greater than 90% of translated amino acid residues strictly conserved. However, a region of marked variability identified previously, corresponding to L po...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20531

    authors: Meissner JD,Seregin SS,Seregin SV,Vyshemirskii OI,Samokhvalov EI,Lvov DK,Netesov SV,Petrov VS

    更新日期:2006-02-01 00:00:00

  • Use of a generic polymerase chain reaction assay detecting human T-lymphotropic virus (HTLV) types I, II and divergent simian strains in the evaluation of individuals with indeterminate HTLV serology.

    abstract::In countries with a low prevalence of human T-lymphotropic virus (HTLV) infection, indeterminate HTLV serologies are a major problem in blood bank screening because of the uncertainties about infection in these cases. The recent discovery of two new types of simian T-lymphotropic viruses (STLV), which give an HTLV-ind...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Vandamme AM,Van Laethem K,Liu HF,Van Brussel M,Delaporte E,de Castro Costa CM,Fleischer C,Taylor G,Bertazzoni U,Desmyter J,Goubau P

    更新日期:1997-05-01 00:00:00

  • Naturally occurring hepatitis B virus X deletions and insertions among Korean chronic patients.

    abstract::Deletions and insertions in the hepatitis B virus (HBV) X region have been associated with severe forms of liver disease, including hepatocellular carcinoma (HCC). However, the molecular epidemiologic features of this virus have been described rarely. Deletions and insertions in the X region were determined by direct ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21938

    authors: Lee SA,Mun HS,Kim H,Lee HK,Kim BJ,Hwang ES,Kook YH,Kim BJ

    更新日期:2011-01-01 00:00:00

  • Paper-based point-of-care testing for cost-effective diagnosis of acute flavivirus infections.

    abstract::Flavivirus infections are a serious healthcare concern in tropical and subtropical countries. Although well-established laboratory tests can provide early diagnosis of acute dengue or Zika infections, access to these tests is limited in developing countries, presenting an urgent need to develop simple, rapid, and robu...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24806

    authors: Bedin F,Boulet L,Voilin E,Theillet G,Rubens A,Rozand C

    更新日期:2017-09-01 00:00:00

  • Association of rhinovirus with exacerbations in young children affected by cystic fibrosis: Preliminary data.

    abstract::Rhinovirus (RV) is a common respiratory viral infection linked to worsening of chronic respiratory diseases including cystic fibrosis (CF) and asthma. RV was tested by RT-PCR in samples (n = 465) collected from the upper (nasal swab, oropharyngeal suction, and sputum) and lower (bronchoalveolar washings) respiratory t...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24794

    authors: Stelzer-Braid S,Liu N,Doumit M,D'Cunha R,Belessis Y,Jaffe A,Rawlinson WD

    更新日期:2017-08-01 00:00:00

  • Clinical relevance and genotypes of circulating noroviruses in northern Taiwan, 2006-2011.

    abstract::The incidence of noroviral gastroenteritis has increased dramatically in recent years, and norovirus (NoV) genogroup II.4 (GII.4) is associated with outbreaks worldwide. The NoV genotypes and their clinical relevance in children hospitalized with acute gastroenteritis between 2006 and 2011 in northern Taiwan were eval...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23728

    authors: Tsai CN,Lin CY,Lin CW,Shih KC,Chiu CH,Chen SY

    更新日期:2014-02-01 00:00:00

  • Detection by PCR of human polyomaviruses BK and JC in immunocompromised individuals and partial sequencing of control regions.

    abstract::Immunocompromised individuals were tested for the presence of the human polyomaviruses JC (JCV) and BK (BKV) by the polymerase chain reaction (PCR). The use of appropriate primers in a nested PCR allowed the detection of both viruses simultaneously. Viruses were differentiated by restriction fragment length analysis o...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890420208

    authors: Schätzl HM,Sieger E,Jäger G,Nitschko H,Bader L,Ruckdeschel G,Jäger G

    更新日期:1994-02-01 00:00:00

  • Coronavirus-like particles in adults in Melbourne, Australia.

    abstract::Coronavirus-like particle(s) (CVLP) are faecal-derived pleomorphic membrane bound virus-like particles characterised by a fringe of club-shaped spikes that measure about 27 nm in length. The association of CVLP with a variety of social, clinical, and epidemiological factors was examined after a 69 month survey of faec...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890290404

    authors: Marshall JA,Thompson WL,Gust ID

    更新日期:1989-12-01 00:00:00

  • Epidemiological and molecular investigation of norovirus and astrovirus infections in Rio Branco, Acre, Northern Brazil: A retrospective study.

    abstract::Norovirus (NoV) is a major cause of nonbacterial acute gastroenteritis (AGE) outbreaks worldwide, with infections reported in semiclosed environments, particularly in hospitals and nursing homes. Astrovirus (HAstV) is prevalent worldwide, especially in developing countries. We aimed to determine the prevalence, spatia...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25395

    authors: Bitencurt ELR,Siqueira JAM,Medeiros TB,Bandeira RDS,de Souza Oliveira D,de Paula Souza E Guimarães RJ,da Silva Soares L,Macarenhas JDP,Teixeira DM,Silva RSU,Loureiro ECB,de Moraes Silva MC,da Silva LD,Gabbay YB

    更新日期:2019-06-01 00:00:00

  • Genetic variants in IFIH1 and DDX58 influence hepatitis C virus clearance in Chinese Han population.

    abstract:AIMS:To investigate the association between two RIG-I-like receptor gene polymorphisms and hepatitis C virus (HCV) infection in Chinese Han population. METHODS:The current study genotyped two selected SNPs (IFIH1 rs3747517 and DDX58 rs9695310) using TaqMan allelic discrimination assay to assess their association with ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25398

    authors: Zhu XB,Zhuo LY,Yue M,Liu M,Zang F,Fan HZ,Wu JJ,Xia XS,Zhang AM,Yu RB,Huang P

    更新日期:2019-06-01 00:00:00

  • Hepatitis B virus genotype D strains from Estonia share sequence similarity with strains from Siberia and may specify ayw4.

    abstract::The genotypes and subtypes of 205 HBV isolates collected during 1989-2002 in Estonia and 14 other regions of the former USSR were determined by sequencing and phylogenetic analysis of the S gene. The in Europe prevailing genotypes, A and D, were also circulating in the whole territory of the former USSR including Esto...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20169

    authors: Tallo T,Norder H,Tefanova V,Krispin T,Priimägi L,Mukomolov S,Mikhailov M,Magnius LO

    更新日期:2004-10-01 00:00:00

  • Foscarnet therapy in chronic hepatitis B virus E antigen carriers.

    abstract::Foscarnet (trisodium phosphonoformate) is a novel antiviral agent that inhibits viral-specific DNA polymerase. In the present study, eight males with chronic HBV carriage (HBeAg and HBV-DNA seropositivity greater than 12 months) showing chronic persistent hepatitis (CPH) or chronic active hepatitis (CAH) on liver biop...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890290214

    authors: Bain VG,Daniels HM,Chanas A,Alexander GJ,Williams R

    更新日期:1989-10-01 00:00:00

  • GBV-C viremia and clinical events in advanced HIV infection.

    abstract::GB Virus C (GBV-C) is a non-pathogenic flavivirus, commonly found in HIV infected patients. Studies suggest a survival benefit of GBV-C viremia in HIV infection. Impact of GBV-C viremia was evaluated on clinical outcome in multidrug-resistant HIV. The OPTIMA study enrolled advanced multidrug-resistant HIV patients wit...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1002/jmv.23845

    authors: Sahni H,Kirkwood K,Kyriakides TC,Stapleton J,Brown ST,Holodniy M,OPTIMA Study Team.

    更新日期:2014-03-01 00:00:00

  • Mix-breeding with HEV-infected swine induced inapparent HEV infection in SPF rabbits.

    abstract::Studies have shown that swine HEV (sHEV) and rabbit HEV (rHEV) can experimentally infect rabbits and swine, respectively. However, no published data have documented isolating sHEV strains from rabbits in natural environment so far. To clarify the possibility of natural cross-species transmission of sHEV to rabbits, th...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24374

    authors: Liu L,Wang L,Xia J,Zhang Y,Zeng H,Liu P,Zou Q,Wang L,Zhuang H

    更新日期:2016-04-01 00:00:00

  • Assessing risk of a short-term antiretroviral therapy discontinuation as a read-out of viral control in immune-based therapy.

    abstract::Although analytical treatment interruption is used as a strategy to test immunotherapeutic agents in HIV-infection, it may pose a risk for study participants. The potential risks of short-term interruption of antiretroviral therapy (ART) during treatment with an autologous dendritic cell immune-based therapy (AGS-004-...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/jmv.23297

    authors: Routy JP,Boulassel MR,Nicolette CA,Jacobson JM

    更新日期:2012-06-01 00:00:00

  • Screening for vaginal shedding of cytomegalovirus in healthy pregnant women using real-time PCR: correlation of CMV in the vagina and adverse outcome of pregnancy.

    abstract::The impact of cytomegalovirus (CMV) infection of the genital tract during pregnancy on adverse pregnancy outcomes is not understood fully. A real-time PCR assay was used to determine vaginal shedding of CMV in 993 healthy pregnant Japanese women and the results were compared with the outcome of pregnancy. CMV DNA was ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20619

    authors: Tanaka K,Yamada H,Minami M,Kataoka S,Numazaki K,Minakami H,Tsutsumi H

    更新日期:2006-06-01 00:00:00

  • Frequent detection of cell-associated HIV-1 RNA in patients with plasma viral load

    abstract::Despite prolonged undetectable plasma viral load some HIV-1 infected patients have been reported to develop resistance-associated mutations leading to treatment failure. The mechanisms for this phenomenon and the point of origin for residual viral evolution are still not elucidated. In order to quantify cell-associate...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20993

    authors: Kupfer B,Matz B,Däumer MP,Roden F,Rockstroh JK,Qurishi N,Spengler U,Kaiser R

    更新日期:2007-10-01 00:00:00

  • The behaviour of recent isolates of human respiratory coronavirus in vitro and in volunteers: evidence of heterogeneity among 229E-related strains.

    abstract::Strains of human coronavirus (HCV) isolated between 1974 and 1976 have been studied in vitro and in volunteers. All strains caused colds in volunteers, and those cultivable in tissue culture (TC) produced significantly more coryza and less sore throat than strains growing only in organ culture (OC). The TC strains wer...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890130208

    authors: Reed SE

    更新日期:1984-01-01 00:00:00

  • Human T-cell lymphotropic virus types I and II (HTLV-I and -II) infection among seroindeterminate cases in Argentina.

    abstract::Human T-cell lymphotropic virus (HTLV) seroindeterminate cases have been reported among blood donors (BD) and in at-risk populations worldwide, including Argentina. The objective of the present work was to study the presence of HTLV-I/II infection and its association to specific Western blot (WB) patterns among health...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20731

    authors: Berini CA,Eirin ME,Pando MA,Biglione MM

    更新日期:2007-01-01 00:00:00

  • Weathering the pandemic: How the Caribbean Basin can use viral and environmental patterns to predict, prepare, and respond to COVID-19.

    abstract::The 2020 coronavirus pandemic is developing at different paces throughout the world. Some areas, like the Caribbean Basin, have yet to see the virus strike at full force. When it does, there is reasonable evidence to suggest the consequent COVID-19 outbreaks will overwhelm healthcare systems and economies. This is par...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/jmv.25864

    authors: de Ángel Solá DE,Wang L,Vázquez M,Méndez-Lázaro PA

    更新日期:2020-09-01 00:00:00

  • HCV in peripheral blood mononuclear cells are predominantly carried on the surface of cells in HIV/HCV co-infected individuals.

    abstract::HCV replication in extra-hepatic reservoirs has been suggested to occur in many tissues including PBMCs. A recent study showed evidence for compartmentalization and evolution of HCV in PBMCs. However, the cells that support HCV replication in PBMCs have not been identified. In this study we have fractionated the PBMC ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21906

    authors: Natarajan V,Kottilil S,Hazen A,Adelsberger J,Murphy AA,Polis MA,Kovacs JA

    更新日期:2010-12-01 00:00:00

  • Effect of age on serum immunoglobulin G subclass antibody responses to inactivated influenza virus vaccine.

    abstract::We previously reported an age-associated impairment of serum immunoglobulin G (IgG) antibody responses to inactivated influenza virus vaccine. The present study extends these observations by examining the IgG subclass distribution of vaccine responses measured by enzyme linked immunosorbent assay in healthy adults age...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890430111

    authors: Powers DC

    更新日期:1994-05-01 00:00:00

  • Experimental studies of acute and recurrent herpes simplex virus infections in the murine heart and dorsal root ganglia.

    abstract::The multiplication of HSV-1 and HSV-2 strains in the heart and the corresponding dorsal root ganglia (DRG) was examined in experimentally infected mice. Infectious HSV-1 was recovered from the heart between the second and fourth day after inoculation and 3 days later from the DRG. Both the heart and DRG yielded infect...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890070211

    authors: Grodums EI,Kuling PJ,Zbitnew A

    更新日期:1981-01-01 00:00:00

  • Real-life 3D therapy failure: Analysis of NS5A 93H RAS plus 108 K polymorphism in complex with ombitasvir by molecular modeling.

    abstract::We report a real-life 3D therapy failure in a patient treated with ombitasvir (OMV)/paritaprevir/ritonavir and dasabuvir without ribavirin (3D-R). He had therapy failure at week 12 after the end of treatment. We detected resistance-associated substitutions (RASs) plus polymorphisms on NS3, NS5A, and NS5B target region...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25073

    authors: Marascio N,Pavia G,Romeo I,Talarico C,Di Salvo S,Reale M,Marano V,Barreca GS,Fabiani F,Perrotti N,De Siena M,Giancotti F,Gravina T,Alcaro S,Artese A,Torti C,Liberto MC,Focà A

    更新日期:2018-07-01 00:00:00