A variable region in the Crimean-Congo hemorrhagic fever virus L segment distinguishes between strains isolated from different geographic regions.

abstract：:Human peripheral blood mononuclear cell (PBMC) proliferative responses to live respiratory syncytial (RS) virus, formalin-inactivated RS (Fl-RS) virus, RS virus F (fusion) protein, and RS virus G (attachment) protein were assessed. All donors responded to challenge with whole RS virus antigens and F and G proteins. F ...

journal_title：Journal of medical virology

authors： Jackson M,Scott R

更新日期：1996-07-01 00:00:00

abstract：:To elucidate the role of host immune status in the evolution and complexity of hepatitis C virus (HCV) quasispecies, three chronic HCV-infected patients who underwent bone marrow transplantation (BMT) were studied. The three transplanted patients' sera were sampled at pre-BMT, 3 months after BMT, and 12 months after B...

journal_title：Journal of medical virology

authors： Ni YH,Chang MH,Chen PJ,Hsu HY,Lu TW,Lin KH,Lin DT

更新日期：1999-06-01 00:00:00

abstract：:Here, we studied the role of nitric oxide (NO) production during the first steps of the respiratory infection of BALB/c mice with herpes simplex virus type 1 (HSV-1), strain F. Nitric oxide synthase II (NOS-II) mRNA and protein were detected by reverse transcription (RT)-PCR and dot blot, respectively in samples of lu...

journal_title：Journal of medical virology

authors： Gamba G,Cavalieri H,Courreges MC,Massouh EJ,Benencia F

更新日期：2004-06-01 00:00:00

abstract：:The criterion standard for the diagnosis of occult hepatitis C virus (HCV) infection is detection of HCV-RNA in liver cells. However, because of the invasive nature of liver biopsy, other methods have been studied. The present study aimed to identify subjects with occult HCV-4 infection among healthy sexual partners o...

journal_title：Journal of medical virology

authors： El Shazly Y,Hemida K,Rafik M,Al Swaff R,Ali-Eldin ZA,GadAllah S

更新日期：2015-03-01 00:00:00

abstract：:The X gene product of human hepatitis B virus, HBx, transactivates the expression of viral and cellular genes through a wide variety of cis elements, including the nuclear factor for IL-6 (NF-IL6) binding sites, although HBx does not appear to bind DNA directly. We previously reported that HBx transactivated the inter...

journal_title：Journal of medical virology

authors： Ohno H,Kaneko S,Lin Y,Kobayashi K,Murakami S

更新日期：1999-05-01 00:00:00

abstract：:Human polyomaviruses HPyV6, HPyV7, TSPyV, HPyV9, MWPyV, and KIPyV have been discovered between 2007 and 2012. TSPyV causes a rare skin disease trichodysplasia spinulosa in immunocompromised patients, the role of remaining polyomaviruses in human pathology is not clear. In this study, we assessed the occurrence of seru...

journal_title：Journal of medical virology

authors： Šroller V,Hamšíková E,Ludvíková V,Musil J,Němečková Š,Saláková M

更新日期：2016-07-01 00:00:00

abstract：:The major risk factor for intrauterine transmission of human cytomegalovirus (HCMV) is a primary infection during pregnancy. The neutralizing antibody response appeared after an average of 13 weeks after seroconversion and therefore the absence of neutralizing titers in HCMV IgG positive pregnant women is a reliable m...

journal_title：Journal of medical virology

authors： Eggers M,Radsak K,Enders G,Reschke M

更新日期：2001-02-01 00:00:00

abstract：:Mitochondrial DNA (mtDNA) of peripheral blood mononuclear cells (PBMCs) collected from Human immunodeficiency virus 1 (HIV-1)-infected patients and healthy controls were measured longitudinally using real-time polymerase chain reaction to evaluate the effects of antiretroviral agents on mtDNA synthesis in vivo and to ...

journal_title：Journal of medical virology

authors： Miura T,Goto M,Hosoya N,Odawara T,Kitamura Y,Nakamura T,Iwamoto A

更新日期：2003-08-01 00:00:00

abstract：:The aim of this study was to assess the seroprevalence, viremia, genotype distribution, and demographic history of hepatitis C virus (HCV) in the Republic of the Congo. Testing was carried out on sera samples collected in 2005 from 807 Bantus belonging to the Kongo, Teke, and Ngala subgroups and 80 Pygmies. Positive H...

journal_title：Journal of medical virology

authors： Cantaloube JF,Gallian P,Bokilo A,Jordier F,Biagini P,Attoui H,Chiaroni J,de Micco P

更新日期：2010-04-01 00:00:00

abstract：:The genotypic inhibitory quotient (GIQ) is the ratio between drug concentration and the number of resistance mutations. However, as different resistance scores can be calculated for the same protease inhibitor, the ability of a GIQ to predict the virological outcome may vary depending on the resistance score used as t...

journal_title：Journal of medical virology

authors： Gianotti N,Galli L,Danise A,Hasson H,Boeri E,Lazzarin A,Castagna A

更新日期：2006-12-01 00:00:00

abstract：:Respiratory viruses were identified by the polymerase chain reaction (PCR) in more than 4,200 specimens collected during 2002 and 2003 in Victoria, Australia from patients admitted to hospitals or participating in an influenza surveillance program. Influenza viruses and picornaviruses were important causes of morbidit...

journal_title：Journal of medical virology

authors： Druce J,Tran T,Kelly H,Kaye M,Chibo D,Kostecki R,Amiri A,Catton M,Birch C

更新日期：2005-01-01 00:00:00

abstract：:Following widespread outbreaks of oyster-associated gastroenteritis in Australia during 1978 in which Norwalk virus was implicated as the causative agent, collaborative studies were undertaken between laboratories in Australia and the United States to confirm the etiology. Immune electron microscopy (IEM) techniques w...

journal_title：Journal of medical virology

authors： Grohmann GS,Greenberg HB,Welch BM,Murphy AM

更新日期：1980-01-01 00:00:00

abstract：:Limited data are available describing human papillomavirus (HPV) genotype distribution among females with cytological abnormalities in Switzerland. Cervical cell specimens obtained from 5,318 women were screened routinely by liquid-based Pap smear. All specimens with cellular abnormalities were analyzed subsequently f...

journal_title：Journal of medical virology

authors： Dobec M,Bannwart F,Kilgus S,Kaeppeli F,Cassinotti P

更新日期：2011-08-01 00:00:00

abstract：:Rotavirus A (RVA) is the leading cause of acute viral gastroenteritis in children under 5 years of age worldwide. G9P[8] is a common RVA genotype that has been persistently prevalent in Jiangsu, China. To determine the genetic diversity of G9P[8] RVAs, 7 representative G9P[8] strains collected from Suzhou Children's H...

journal_title：Journal of medical virology

authors： Xu C,Fu J,Ai J,Zhang J,Liu C,Huo X,Bao C,Zhu Y

更新日期：2018-09-01 00:00:00

abstract：:Recently developed monoclonal antibodies against the 42,000-dalton major inner capsid protein were used in an enzyme immunoassay to subgroup a total of 156 rotavirus specimens obtained from Japanese infants and young children with acute gastroenteritis during the period between December 1981 and April 1983. Only 2 spe...

journal_title：Journal of medical virology

authors： Nakagomi O,Nakagomi T,Oyamada H,Suto T

更新日期：1985-09-01 00:00:00

abstract：:Influenza A(H1N1)pdm09 virus pandemic struck India in 2009 and continues to cause outbreaks in its post-pandemic phase. Diminutive information is available about influenza A(H1N1)pdm09 from central India. This observational study presents epidemiological and molecular findings for the period of 6 years. Throat swab sa...

journal_title：Journal of medical virology

authors： Sahu M,Singh N,Shukla MK,Potdar VA,Sharma RK,Sahare LK,Ukey MJ,Barde PV

更新日期：2018-03-01 00:00:00

abstract：:Response to ribavirin therapy (1,000-1,200 mg/day for 6 months) was evaluated in nine patients with chronic hepatitis C virus (HCV) infections who had previously failed to respond to a 6-month course of alpha-interferon. All had chronic active hepatitis with elevated serum aminotransferase activities (mean +/- SD = 13...

journal_title：Journal of medical virology

authors： Koskinas J,Tibbs C,Saleh MG,Pereira LM,McFarlane IG,Williams R

更新日期：1995-01-01 00:00:00

abstract：:Chronic hepatitis B virus (HBV) infection is the result of an inadequate immune response towards the virus. Dendritic cells (DCs), as the most efficient professional antigen-presenting cells (APCs), possess the strongest antigen presenting the effect in the body and can stimulate the initial T cell activation and prol...

journal_title：Journal of medical virology

authors： Sun HH,Zhou DF,Zhou JY

更新日期：2016-01-01 00:00:00

abstract：:Knowledge of the precise timing of SARS-CoV-2 infection may be of clinical and epidemiological relevance. The presence of low-avidity IgGs has conventionally been considered an indicator of recent infection. Here, we carried out qualitative assessment of SARS-CoV-2-specific antibody avidity using an urea (6M) dissocia...

journal_title：Journal of medical virology

authors： Valdivia A,Torres I,Huntley D,Alcaraz MJ,Albert E,Colomina J,Ferrer J,Carratalá A,Navarro D

更新日期：2021-02-01 00:00:00

abstract：:Management of patients infected with high-risk HPV (hrHPV) despite normal colposcopy following abnormal cytology remains a clinical challenge. The aim of this study was to evaluate if, in that specific population, initial HPV 16 and HPV 18 viral loads are predictive of infection clearance over a 24-month follow-up. A ...

journal_title：Journal of medical virology

authors： Carcopino X,Henry M,Mancini J,Giusiano S,Boubli L,Olive D,Tamalet C

更新日期：2012-06-01 00:00:00

abstract：:Cytomegalovirus (CMV) has been implicated in vascular pathologies and may warrant inclusion in cardiovascular predictive algorithms. We addressed this in healthy older adults and renal transplant recipients (RTR) as they retain a high burden of CMV. RTR (n  =  45) stable more than 2 years after transplantation and 58 ...

journal_title：Journal of medical virology

authors： Affandi JS,Lee S,Chih H,Brook E,Waters S,Howson P,Reid CM,Irish A,Price P

更新日期：2020-02-04 00:00:00

abstract：:Development of hepatitis B virus (HBV)-resistant strains following nucleos(t)ide analog treatment is a major medical concern. This report describes a case of an adult patient with chronic HBV infection, sequentially treated with the nucleos(t)ide analogues, lamivudine, adefovir, and entecavir. During monotherapy with ...

journal_title：Journal of medical virology

authors： Rodriguez-Frias F,Jardi R,Schaper M,Gimferrer M,Elefsiniotis I,Tabernero D,Esteban R,Buti M

更新日期：2007-11-01 00:00:00

abstract：:The prevalence of coinfection and superinfection with the delta agent was studied in 2,645 hepatitis B surface antigen (HBsAg)-positive subjects from six countries and nine islands in the Western Pacific region. The study group comprised 262 patients with acute hepatitis B and 2,383 chronic carriers of HBsAg, of whom ...

journal_title：Journal of medical virology

authors： Dimitrakakis M,Crowe S,Gust I

更新日期：1986-04-01 00:00:00

abstract：:Our studies of rotavirus challenge in adult volunteers enabled us to evaluate the relationship of pre-existing antirotavirus fecal IgA antibody to infection and illness and to investigate the local response to this infection. No relationship could be found between the pre-existing levels of fecal antirotavirus IgA ant...

journal_title：Journal of medical virology

authors： Bernstein DI,Ziegler JM,Ward RL

更新日期：1986-12-01 00:00:00

abstract：:Liver fibrosis is accelerated in human immunodeficiency virus/hepatitis C virus (HIV/HCV) coinfected compared with HCV monoinfected patients, due to multiple cofactors. Recently, HLA-B18 haplotype has been associated with short-term liver disease progression in this population. Our aim was to assess the influence of H...

journal_title：Journal of medical virology

authors： Bavaro DF,Saracino A,Fiordelisi D,Bruno G,Ladisa N,Monno L,Angarano G

更新日期：2019-05-01 00:00:00

abstract：:Infection with putative non-A to E hepatitis virus, designated GB virus C (GBV-C), was surveyed in 286 patients with chronic liver disease in Japan. RNA of GBV-C was detected, by reverse-transcription polymerase chain reaction with nested primers from the 5'-noncoding region, in 19 patients (6.6%) at a frequency highe...

journal_title：Journal of medical virology

authors： Sugai Y,Nakayama H,Fukuda M,Sawada N,Tanaka T,Tsuda F,Okamoto H,Miyakawa Y,Mayumi M

更新日期：1997-03-01 00:00:00

abstract：:Avidity maturation of IgG antibody responses directed against the structural proteins of rubella virus (E1, E2, and C) as well as whole rubella virus (RV) was assessed at sequential time intervals in 7 individuals following serologically confirmed wild rubella infection. Individual structural proteins were purified fr...

journal_title：Journal of medical virology

authors： Mauracher CA,Mitchell LA,Tingle AJ

更新日期：1992-03-01 00:00:00

abstract：:To assess the prevalence of HPV infection in the genital tracts of women with normal PAP smears, a random series of 109 women was reexamined using colposcopy, a further PAP smear, and punch biopsies taken from the cervix (in 33 cases), vagina (212 cases), and anus (20 cases). The biopsy material was examined using rou...

journal_title：Journal of medical virology

authors： Syrjänen S,Saastamoinen J,Chang FJ,Ji HX,Syrjänen K

更新日期：1990-08-01 00:00:00

abstract：:Human herpesvirus 6 (HHV-6) is classified as two distinct species: HHV-6A and B. HHV-6B infection can cause several clinical manifestations in transplant recipients including encephalitis, bone marrow suppression, and pneumonitis. In contrast to HHV-6B, the clinical features of HHV-6A infection remain largely undefine...

journal_title：Journal of medical virology

authors： Ihira M,Yamaki A,Kato Y,Higashimoto Y,Kawamura Y,Yoshikawa T

更新日期：2016-09-01 00:00:00

abstract：:Five HIV-1 isolates were obtained sequentially from a single seropositive individual during the later stages of AIDS. Four of these isolates were adapted to grow in a continuous human T-lymphocytic cell line. Comparative biological and biochemical studies of the virus isolates were made using persistently infected cul...

journal_title：Journal of medical virology

authors： Farrar GH,Roff MA,Amin T,Ball J,Parrett AM,Battacharyya U,Booth J,Wansbrough-Jones MH,Greenaway PJ

更新日期：1991-06-01 00:00:00