Effects of ribavirin on intrahepatic and extrahepatic expression of hepatitis C virus in interferon nonresponsive patients.

abstract：:Human cytomegalovirus (HCMV) is a major cause of morbidity and mortality in immunocompromised patients, such as renal transplant recipients. Analysis of the gene encoding the envelope glycoprotein B (gB) showed that clinical isolates adopted one of the sequence configurations, permitting the isolates to be assigned a ...

journal_title：Journal of medical virology

authors： Carraro E,Granato CF

更新日期：2003-06-01 00:00:00

abstract：:Human herpes virus type 6 (HHV-6) DNA has been suggested to be a cofactor to human papillomavirus (HPV) in cervical cancer. In a cross-sectional study, we investigated the association between HHV-6 DNA detected in cervical brushings and high-grade squamous intraepithelial lesions (HSIL), while controlling for genital ...

journal_title：Journal of medical virology

authors： Tran-Thanh D,Koushik A,Provencher D,Drouin P,Dubuc-Lissoir J,Gauthier P,Allaire G,Kornegay J,Franco E,Coutlée F

更新日期：2002-12-01 00:00:00

abstract：:In order to analyse the relationships between enteroviral replication and the myocardial damage at the onset of chronic cardiac infection, 2 mouse strains with different degrees of immunological competence (NMRI nu/nu, DBA/2) were infected by a myocarditic Coxsackie virus B3 (CVB3-M1) variant. At 31 days post-inoculat...

journal_title：Journal of medical virology

authors： Andréoletti L,Hober D,Becquart P,Belaich S,Copin MC,Lambert V,Wattré P

更新日期：1997-06-01 00:00:00

abstract：:Sera from patients with sandfly fever caused by Toscana virus (TOSV) infection were tested by immunoblot for specific antibody response to TOSV derived from infected Vero-E6 cells. The 28 kDa TOSV nucleoprotein (N) was identified as the major immunodominant protein recognized by immunoblot. In sera of patients with ac...

journal_title：Journal of medical virology

authors： Schwarz TF,Gilch S,Pauli C,Jäger G

更新日期：1996-06-01 00:00:00

abstract：:A cohort of 127 nursing home residents aged 60-98 years were vaccinated during the winter of 1985-86 with the A-Chile 1/83 (C), A-Philippines 2/82 (P), and B-USSR (B) commercial influenza vaccines. Before vaccination 40%, 23%, and 69% were susceptible to influenza Ac, Ap, and B, respectively [hemagglutinin inhibition ...

journal_title：Journal of medical virology

authors： Keren G,Segev S,Morag A,Zakay-Rones Z,Barzilai A,Rubinstein E

更新日期：1988-05-01 00:00:00

abstract：:Persistent Epstein-Barr virus (EBV) infection is controlled tightly by virus-specific T cells. EBV infection is reactivated intermittently over time, even in apparently healthy carriers. Changes in frequency and reactivity of memory T cells, particularly of CD8(+) origin, have not been assessed in this context. It is ...

journal_title：Journal of medical virology

authors： Vogl BA,Fagin U,Nerbas L,Schlenke P,Lamprecht P,Jabs WJ

更新日期：2012-01-01 00:00:00

abstract：:Long-term treatment with retrotranscriptase (RT) inhibitors eventually leads to the development of drug resistance. Drug-related mutations occur naturally and these can be found in hepatitis B virus (HBV) carriers who have never received antiviral therapy. HBsAg are overlapped with RT domain, thus nucleot(s)ide analog...

journal_title：Journal of medical virology

authors： Fernández-Galindo DA,Sánchez-Ávila F,Bobadilla-Morales L,Gómez-Quiróz P,Bueno-Topete M,Armendáriz-Borunda J,Sánchez-Orozco LV

更新日期：2015-06-01 00:00:00

abstract：:To evaluate the variation over time of seroreactivity to human papillomavirus type 11 (HPV-11) according to disease outcome, we selected a sample of 42 condyloma acuminatum patients from a group of subjects enrolled in a placebo-controlled trial of three alpha-interferon preparations administered parenterally for the ...

journal_title：Journal of medical virology

authors： Bonnez W,Da Rin C,Rose RC,Tyring SK,Reichman RC

更新日期：1993-04-01 00:00:00

abstract：:The reliability of the polymerase chain reaction (PCR) for prenatal diagnosis of human cytomegalovirus (HCMV) infection was determined by retrospective testing of 35 amniotic fluids identified previously as positive or negative for HCMV by virus isolation. Amniocentesis was performed in 26 pregnant women with primary ...

journal_title：Journal of medical virology

authors： Revello MG,Baldanti F,Furione M,Sarasini A,Percivalle E,Zavattoni M,Gerna G

更新日期：1995-12-01 00:00:00

abstract：:The seroprevalence of antibodies to hepatitis E virus (HEV) and hepatitis A virus (HAV) was determined in a community-based sample in innercity London where socioeconomic conditions were expected to result in a high prevalence of antibodies to HAV, and in which the presence of immigrants from the developing world pose...

journal_title：Journal of medical virology

authors： Bernal W,Smith HM,Williams R

更新日期：1996-07-01 00:00:00

abstract：:HIV-1 infections due to non-B subtypes are increasing rapidly in number and spreading across Europe. The genetic nature of HIV-1 non-B variants containing subtype G sequences at the protease (PR)-coding region are described from 48 unrelated subjects living in Spain. Phylogenetic analyses of the HIV-1 reverse transcri...

journal_title：Journal of medical virology

authors： Holguín A,Alvarez A,Soriano V

更新日期：2005-03-01 00:00:00

abstract：:Mouse mammary tumor virus (MMTV) is a hormonally regulated, oncogenic virus of mice. MMTV-like virus DNA has previously been detected in human breast cancers, liver disease, and liver cancers. It is hypothesized that local hormonal effects might be of primary importance in determining MMTV-like virus detection in huma...

journal_title：Journal of medical virology

authors： Johal H,Faedo M,Faltas J,Lau A,Mousina R,Cozzi P,Defazio A,Rawlinson WD

更新日期：2010-05-01 00:00:00

abstract：AIMS:To investigate the association between two RIG-I-like receptor gene polymorphisms and hepatitis C virus (HCV) infection in Chinese Han population. METHODS:The current study genotyped two selected SNPs (IFIH1 rs3747517 and DDX58 rs9695310) using TaqMan allelic discrimination assay to assess their association with ...

journal_title：Journal of medical virology

authors： Zhu XB,Zhuo LY,Yue M,Liu M,Zang F,Fan HZ,Wu JJ,Xia XS,Zhang AM,Yu RB,Huang P

更新日期：2019-06-01 00:00:00

abstract：:In order to elucidate the pathogenesis of variant B human herpesvirus 6 (HHV-6) infection in skin tissues, an A431 cell line was inoculated with variant B HHV-6. HHV-6 causes abortive infection in the A431 cells, because neither late antigen (OHV-3 antigen) nor progeny virus is produced. Maximum levels of HHV-6 antige...

journal_title：Journal of medical virology

authors： Yoshikawa T,Goshima F,Akimoto S,Ozaki T,Iwasaki T,Kurata T,Asano Y,Nishiyama Y

更新日期：2003-09-01 00:00:00

abstract：:The seroprevalence of hepatitis A antibodies in travellers attending London Travel Clinics increases with age and screening may eliminate the need for vaccination at present for approximately 40% of adults. The duration of protection by current hepatitis A vaccine(s) is still to be established. ...

journal_title：Journal of medical virology

authors： Zuckerman JN,Powell L

更新日期：1994-12-01 00:00:00

abstract：:Crimean-Congo hemorrhagic fever (CCHF) is an infectious disease that is caused by CCHF virus. A family of transmembrane receptors called as Toll-like receptors (TLRs) selectively acts in recognizing a wide range of microbial components and endogenous molecules released by damaged tissue and have been preserved through...

journal_title：Journal of medical virology

authors： Engin A,Arslan S,Özbilüm N,Bakir M

更新日期：2016-10-01 00:00:00

abstract：:Epstein-Barr virus (EBV) is an important DNA tumor virus that is associated with approximately 10% of gastric carcinomas and 99% of nasopharyngeal cancers (NPC). DNA methylation and microRNAs (miRNAs) are the most studied epigenetic mechanisms that can prompt disease susceptibility. This study aimed to detect the effe...

journal_title：Journal of medical virology

authors： Zhao Z,Liu W,Liu J,Wang J,Luo B

更新日期：2017-10-01 00:00:00

abstract：:To characterize the state of dual infection with hepatitis B virus (HBV) and hepatitis C virus (HCV), HBV-DNA and HCV-RNA levels were determined by spot hybridization or polymerase chain reaction in the sera of patients who were positive for both hepatitis B surface antigen and HCV antibody. Among 27 patients who show...

journal_title：Journal of medical virology

authors： Koike K,Yasuda K,Yotsuyanagi H,Moriya K,Hino K,Kurokawa K,Iino S

更新日期：1995-02-01 00:00:00

abstract：:Inosine triphosphatase (ITPA) gene variants can protect against ribavirin (RBV)-induced anemia in patients treated for chronic hepatitis C. The aim of this study was to determine the relationship between genetic variants of ITPA polymorphism, anemia, RBV dose reduction, and treatment response in hepatitis C virus (HCV...

journal_title：Journal of medical virology

authors： El Raziky M,Zayed NA,Abdel Baki A,Mansour SA,Shahin RMH

更新日期：2017-10-01 00:00:00

abstract：:Adhesion molecules are essential for the immune response. They are involved in the regulation of cell-to-cell contact, thereby enabling leukocytes to communicate. Circulating forms of adhesion molecules are found in the serum of healthy individuals. Raised levels have been associated with disease severity in HCV and o...

journal_title：Journal of medical virology

authors： Murgue B,Cassar O,Deparis X

更新日期：2001-09-01 00:00:00

abstract：:The objectives of this study were to evaluate the reliability of herpes simplex virus (HSV) PCR testing in cerebrospinal fluid (CSF) for the detection of herpes simplex encephalitis. This was done by examining retrospectively the clinical follow-up of a large group of patients tested routinely by HSV-PCR. In addition,...

journal_title：Journal of medical virology

authors： Puchhammer-Stöckl E,Presterl E,Croÿ C,Aberle S,Popow-Kraupp T,Kundi M,Hofmann H,Wenninger U,Gödl I

更新日期：2001-08-01 00:00:00

abstract：:Chronic HCV infection has emerged as a complex multifaceted disease with manifestations extending beyond the liver. HCV plays a direct role in glucose metabolism leading to both insulin resistance and type 2 diabetes. To evaluate the changes in the glycemic state following Sofosbuvir-based treatment regimens in diabet...

journal_title：Journal of medical virology

authors： Abdel Alem S,Elsharkawy A,Fouad R,Adel E,Abdellatif Z,Musa S,Nagy A,Hussein MS,Yosry A,Esmat G

更新日期：2017-12-01 00:00:00

abstract：:GII.b norovirus is an obligatory recombinant with an open reading frame (ORF) 1 comprising the GII.b genotype and the ORF 2 region corresponding to one of a number of other norovirus genotypes. GII.b is the second most common genotype after GII.4 associated with gastroenteritis outbreaks in Victoria, Australia. The st...

journal_title：Journal of medical virology

authors： Bruggink LD,Marshall JA

更新日期：2013-08-01 00:00:00

abstract：:Co-infection with hepatitis delta virus (HDV) and hepatitis B virus (HBV) has been shown to be associated with a more severe form of acute and chronic hepatitis. Cloning and expression of recombinant HDV antigen (rHDAg) in Escherichiacoli are described. Using purified rHDAg, a cost-effective indirect anti-HDV enzyme-l...

journal_title：Journal of medical virology

authors： Shen L,Gu Y,Sun L,Yang Y,Wang F,Li Y,Bi S

更新日期：2012-03-01 00:00:00

abstract：:A total of 102,600 upper respiratory infections (URI) were recorded among young military conscripts in the Finnish Defence Forces during the study period from October 1991 to March 1994. This period covered three outbreaks caused by H3N2-subtype influenza A virus and one outbreak of influenza B. During the 1991/92 out...

journal_title：Journal of medical virology

authors： Pyhälä R,Visakorpi R,Ikonen N,Kleemola M

更新日期：2004-02-01 00:00:00

abstract：:Progressive multifocal leukoencephalopathy (PML), a viral-induced demyelinating disease, is becoming relatively common, while many diagnostic and pathogenetic aspects remain to be clarified. A study was therefore undertaken in 64 AIDS patients suffering from various neurological disorders, including PML (12 subjects),...

journal_title：Journal of medical virology

authors： Ferrante P,Caldarelli-Stefano R,Omodeo-Zorini E,Cagni AE,Cocchi L,Suter F,Maserati R

更新日期：1997-07-01 00:00:00

abstract：:The predictive value of two methods for measuring HIV RNA concentration in plasma was assessed in relation to CD4 lymphocyte counts during the asymptomatic period of infection. The design was a retrospective longitudinal case-control study for a mean period of 60 months involving 20 asymptomatic patients included in t...

journal_title：Journal of medical virology

authors： Delamare C,Burgard M,Deveau C,Chaix ML,Ivanoff S,Ramirez D,Tachet A,Bary M,Rouzioux C

更新日期：1998-01-01 00:00:00

abstract：:To determine the influence of ageing per se as well as of priming histories on the antibody response to influenza vaccination, haemagglutination inhibition (HI), ELISA IgG, IgA, IgM and neutralizing antibody titres were studied in 43 healthy young subjects (mean age 23 years) and 55 healthy elderly people (mean age 79...

journal_title：Journal of medical virology

authors： Remarque EJ,de Bruijn IA,Boersma WJ,Masurel N,Ligthart GJ

更新日期：1998-05-01 00:00:00

abstract：:Sera from 79 patients with acute self-limiting hepatitis, 17 patients with acute hepatitis B evolving into chronic HBsAg carriership, and 43 chronic HBsAg carriers without a history of acute hepatitis were analyzed for presence of hepatitis B virus (HBV)-DNA by a molecular hybridization technique. In acute self-limiti...

journal_title：Journal of medical virology

authors： Moestrup T,Hansson BG,Widell A,Blomberg J,Nordenfelt E

更新日期：1985-12-01 00:00:00

abstract：:The epidemiology of HTLV-I infection in female prostitutes was studied in a survey of 395 prostitutes from Callao, Peru (the port city of Lima), 72 prostitutes from Iquitos, Peru (another port city on the Amazon River), and 510 prenatal clinic patients from Lima. Prostitutes reported a mean of 8.8 years (range, 1-39 y...

journal_title：Journal of medical virology

authors： Wignall FS,Hyams KC,Phillips IA,Escamilla J,Tejada A,Li O,Lopez F,Chauca G,Sanchez S,Roberts CR

更新日期：1992-09-01 00:00:00