Genetic variants in IFIH1 and DDX58 influence hepatitis C virus clearance in Chinese Han population.

abstract：:Complete coding regions were sequenced for two new enterovirus genomes: EV-B93 previously identified by VP1 sequencing, derived from a child with acute flaccid paralysis in the Democratic Republic of Congo; and EV-C95 from a French soldier with acute gastroenteritis in Djibouti. The EV-B93 P1 had more than 30% nucleot...

journal_title：Journal of medical virology

authors： Junttila N,Lévêque N,Magnius LO,Kabue JP,Muyembe-Tamfum JJ,Maslin J,Lina B,Norder H

更新日期：2015-03-01 00:00:00

abstract：:Junin virus infection in guinea pigs is known to be similar to human Argentine hemorrhagic fever (AHF). The guinea pig was chosen as a model for transplacental transmission of Junin virus, as both guinea pig and man have a similar placental structure. Pregnant guinea pigs were infected with the pathogenic XJ strain of...

journal_title：Journal of medical virology

authors： Sangiorgio P,Weissenbacher MC

更新日期：1983-01-01 00:00:00

abstract：:Rotavirus is the most common etiological cause of acute viral gastroenteritis in infants and young children worldwide, yet its role in the adult population is less well understood. We have recently identified rotavirus as the causative agent of severe diarrhea in adults, specifically in two gastroenteritis outbreaks i...

journal_title：Journal of medical virology

authors： Feeney SA,Mitchell SJ,Mitchell F,Wyatt DE,Fairley D,McCaughey C,Coyle PV,O'Neill HJ

更新日期：2006-08-01 00:00:00

abstract：:DNA samples from recurrent condylomata acuminata biopsies of Greek males and females were examined for the presence of human papillomavirus (HPV) DNA using high-stringency Southern blot hybridization analysis. Of the twenty-six biopsies, 25 were positive for the HPV 6/11-related DNA sequences, and when further analyze...

journal_title：Journal of medical virology

authors： Labropoulou V,Balamotis A,Tosca A,Rotola A,Mavromara-Nazos P

更新日期：1994-03-01 00:00:00

abstract：:Little is known on the association between clinical factors and coronavirus disease 2019 (COVID-19) more than 15 days after diagnosis. We conducted a multicentric prospective cohort of COVID-19 hospitalized patients to describe clinical, biological, and virological characteristics at hospital admission and over time, ...

journal_title：Journal of medical virology

authors： Yazdanpanah Y,French COVID cohort investigators and study group.

更新日期：2020-10-15 00:00:00

abstract：:The effectiveness of a daily continuous infusion of interferon-alpha was evaluated in 12 patients (10 males, 2 females; mean age of 33 years, range 19-62) with biopsy-proven chronic active hepatitis C. Nine million units (MU) of recombinant interferon-alpha 2A (rIFN-alpha 2A) were administered by continuous subcutaneo...

journal_title：Journal of medical virology

authors： Carreño V,Tapia L,Ryff JC,Quiroga JA,Castillo I

更新日期：1992-07-01 00:00:00

abstract：:The S RNA genome segment of hantaviruses carried by Arvicolinae and Sigmodontinae rodents encodes the nucleocapsid (N) protein and has an overlapping (+1) open reading frame (ORF) for a putative nonstructural protein (NSs). The aim of this study was to determine whether the ORF is functional. A protein corresponding t...

journal_title：Journal of medical virology

authors： Jääskeläinen KM,Kaukinen P,Minskaya ES,Plyusnina A,Vapalahti O,Elliott RM,Weber F,Vaheri A,Plyusnin A

更新日期：2007-10-01 00:00:00

abstract：:The mechanisms underlying chronicity of hepatitis C virus (HCV) infection are poorly understood, but the importance of impaired viral clearance by the immune system has been suggested. The prevalence of HCV infection of peripheral blood mononuclear cells (PBMC) was in investigated in 34 persistently infected patients ...

journal_title：Journal of medical virology

authors： Zignego AL,De Carli M,Monti M,Careccia G,La Villa G,Giannini C,D'Elios MM,Del Prete G,Gentilini P

更新日期：1995-09-01 00:00:00

abstract：:Following widespread outbreaks of oyster-associated gastroenteritis in Australia during 1978 in which Norwalk virus was implicated as the causative agent, collaborative studies were undertaken between laboratories in Australia and the United States to confirm the etiology. Immune electron microscopy (IEM) techniques w...

journal_title：Journal of medical virology

authors： Grohmann GS,Greenberg HB,Welch BM,Murphy AM

更新日期：1980-01-01 00:00:00

abstract：:Type 1 immunity appears to be diminished in healthy Japanese carriers of human T-lymphotropic virus type I (HTLV-I), but type 2 status remains undetermined. To further examine the subclinical effect of HTLV-I on host immunity, we measured serum antibodies to the Epstein-Barr virus (EBV) in 415 healthy Japanese adults ...

journal_title：Journal of medical virology

authors： Birmann BM,Mueller NE,Okayama A,Hsieh CC,Tsubouchi H,Harn D,Stuver SO

更新日期：2006-06-01 00:00:00

abstract：:The long-term efficacy of lamivudine therapy in patients with hepatitis B virus (HBV) infection is still not clear. In this study, 20 non-cirrhotic Japanese patients infected with HBV received lamivudine therapy for more than 1 year and were followed for a median period of 8.5 years (range, 6.7-8.7 years). The rates o...

journal_title：Journal of medical virology

authors： Akuta N,Suzuki F,Suzuki Y,Sezaki H,Hosaka T,Someya T,Kobayashi M,Saitoh S,Arase Y,Ikeda K,Kobayashi M,Kumada H

更新日期：2005-04-01 00:00:00

abstract：:Subviral particles of hepatitis B virus have been used to present foreign epitopes. We attempted to present the hydrophilic domains of E2 envelope protein of hepatitis C virus (HCV) as a fusion protein with hepatitis B virus surface antigen (HBsAg). The five hydrophilic domains of HCV E2 antigen were inserted into HBs...

journal_title：Journal of medical virology

authors： Lee IH,Kim CH,Ryu WS

更新日期：1996-10-01 00:00:00

abstract：:Epstein-Barr virus (EBV) serology continues to be the first diagnostic test when infectious mononucleosis is suspected. Due to possible mild immunosuppression in competitive athletes, EBV reactivation determined by increases in salivary viral load have been identified as one possible cause in recurrent respiratory inf...

journal_title：Journal of medical virology

authors： Pottgiesser T,Schumacher YO,Wolfarth B,Schmidt-Trucksäss A,Bauer G

更新日期：2012-09-01 00:00:00

abstract：:Genetically different subpopulations were identified and purified from Japanese Encephalitis virus (JEV). Those with small plaques (SPs; <2 mm in diameter), derived from strains of T1P1, CJN, and CC27, were more competent than those with large plaques (LPs; >5 mm in diameter) when passaged in Neuro-2a cells. Differenc...

journal_title：Journal of medical virology

authors： Chiou SS,Liu H,Chuang CK,Lin CC,Chen WJ

更新日期：2005-08-01 00:00:00

abstract：:The presence of antibody to hepatitis A virus (anti-HAV) in 60% of procured owl monkeys (Aotus trivirgatus) held within the United States prompted a study of recently captured A trivirgatus in Panama. Only 2 of 145 newly captured monkeys, but all of 35 A trivirgatus held within a colony for over 100 days, were found t...

journal_title：Journal of medical virology

authors： Lemon SM,LeDuc JW,Binn LN,Escajadillo A,Ishak KG

更新日期：1982-01-01 00:00:00

abstract：:Previous studies on patients who develop drug resistant HIV-1 variants have shown that continued use of failing regimens might provide clinical benefit. However, the effect of long-term exposure to drug resistant variants may lead to emergence of compensatory mutations that may jeopardize this effect. In this study, w...

journal_title：Journal of medical virology

authors： Machouf N,Thomas R,Nguyen VK,Trottier B,Boulassel MR,Wainberg MA,Routy JP

更新日期：2006-05-01 00:00:00

abstract：:Stored demographic data and HIV RT and protease sequences of 877 HIV patients attending for the first time the HIV/AIDS outpatient clinics of a reference Infectious Diseases centre in Northern Italy between 1999 and 2006 were stratified by 3-year spanning periods according to date of HIV infection. In the period 1980-...

journal_title：Journal of medical virology

authors： Baldanti F,Paolucci S,Ravasi G,Maccabruni A,Moriggia A,Barbarini G,Maserati R

更新日期：2008-06-01 00:00:00

abstract：:It have been suggested that hepatitis B virus (HBV) pre-S deletions may play a role in hepatocarcinogenesis. The aim of the study was to determine the prevalence of pre-S deletions in chronic hepatitis B patients in Hong Kong, the factors associated with the deletions and its relationship with hepatitis B e antigen (H...

journal_title：Journal of medical virology

authors： Yeung P,Wong DK,Lai CL,Fung J,Seto WK,Yuen MF

更新日期：2010-11-01 00:00:00

abstract：:Flavivirus infections are a serious healthcare concern in tropical and subtropical countries. Although well-established laboratory tests can provide early diagnosis of acute dengue or Zika infections, access to these tests is limited in developing countries, presenting an urgent need to develop simple, rapid, and robu...

journal_title：Journal of medical virology

authors： Bedin F,Boulet L,Voilin E,Theillet G,Rubens A,Rozand C

更新日期：2017-09-01 00:00:00

abstract：:During the period between 1998 and 2008, 48 representative measles viruses (MeVs) circulating in Thailand were subjected to genetic characterization. Three genotypes, G2, D5, and D9 were detected. The results suggested that measles genotype D5, which has been circulating since at least 1998, is the endemic genotype in...

journal_title：Journal of medical virology

authors： Pattamadilok S,Incomserb P,Primsirikunawut A,Lukebua A,Rota PA,Sawanpanyalert P

更新日期：2012-05-01 00:00:00

abstract：:An outbreak of dengue type 2 occurred in North Queensland, Australia, between December 1996 and April 1997. Culture of serum in the Aedes albopictus C6/36 cell line with detection using immunofluorescent staining was compared with a culture-amplified detection system using an immunoperoxidase staining method in a micr...

journal_title：Journal of medical virology

authors： Gleeson F,McBride J,Norton R

更新日期：1999-02-01 00:00:00

abstract：:A pandemic of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection broke out all over the world; however, epidemiological data and viral shedding in pediatric patients are limited. We conducted a retrospective, multicenter study, and followed-up with all children from the families with SARS-CoV-2 inf...

journal_title：Journal of medical virology

authors： Hua CZ,Miao ZP,Zheng JS,Huang Q,Sun QF,Lu HP,Su FF,Wang WH,Huang LP,Chen DQ,Xu ZW,Ji LD,Zhang HP,Yang XW,Li MH,Mao YY,Ying MZ,Ye S,Shu Q,Chen EF,Liang JF,Wang W,Chen ZM,Li W,Fu JF

更新日期：2020-11-01 00:00:00

abstract：:The Balkan Peninsula and Bulgaria in particular, is a well-known endemic region for Crimean-Congo hemorrhagic fever (CCHF). This study describes the prevalence of Crimean-Congo hemorrhagic fever virus (CCHFV) among tick populations from areas, previously recognized with emerging cases of CCHF disease in humans. These ...

journal_title：Journal of medical virology

authors： Gergova I,Kunchev M,Kamarinchev B

更新日期：2012-04-01 00:00:00

abstract：:In this study, we aimed to investigate the changes of lymphocyte subsets (CD3+ , CD4+ , CD8+ ) and inflammatory factors (interleukin-6 [IL-6], hypersensitive C-reactive protein [HS-CRP], and procalcitonin [PCT]) of alveolar lavage fluid in patients with severe corona virus-2019 (COVID-19) pneumonia and their clinical ...

journal_title：Journal of medical virology

authors： Liao L,Yang GH

更新日期：2021-01-28 00:00:00

abstract：:To characterize cytotoxic T lymphocytes (CTLs) that appeared in circulation during lamivudine therapy, we analyzed HBV-specific CTLs using HLA-A24 tetramer and HBcAg-specific Th1 cells in patients receiving lamivudine therapy. Six patients (HLA-A24(+)) with chronic hepatitis B, six patients (HLA-A24(-)) with chronic h...

journal_title：Journal of medical virology

authors： Kondo Y,Asabe S,Kobayashi K,Shiina M,Niitsuma H,Ueno Y,Kobayashi T,Shimosegawa T

更新日期：2004-11-01 00:00:00

abstract：:Immunological factors, such as cytokines, have been proposed as a cause of changes in the lipid profile of dengue patients. We studied whether serum lipid levels and serum TNF-α levels are associated in a group of dengue patients from an endemic region in the Northwest of Mexico. We found statistically important diffe...

journal_title：Journal of medical virology

authors： Osuna-Ramos JF,Rendón-Aguilar H,Reyes-Ruiz JM,Del Ángel RM,Romero-Utrilla A,Ríos-Burgueño ER,Velarde-Rodriguez I,Velarde-Félix JS

更新日期：2018-06-01 00:00:00

abstract：:Enterovirus infections are usually mild but can also cause severe illnesses and play a role in chronic diseases, such as cardiomyopathies and type 1 diabetes. Host response to the invading virus can markedly modulate the course of the infection, and this response varies between individuals due to the polymorphism of i...

journal_title：Journal of medical virology

authors： Hämäläinen S,Nurminen N,Ahlfors H,Oikarinen S,Sioofy-Khojine AB,Frisk G,Oberste MS,Lahesmaa R,Pesu M,Hyöty H

更新日期：2014-08-01 00:00:00

abstract：:Immune-specific IFN (IFN) is produced by the peripheral blood mononuclear leukocytes (PBML) of greater than 95% of HSV-seropositive humans with infrequent recurrences of herpes labialis [Green, Yeh, and Overall, 1981]. However, herpes virus-induced immune-specific IFN was produced by PBML from only 33 of 48 (68.8%) pe...

journal_title：Journal of medical virology

authors： Green JA,Weiss PN,Yeh TJ,Spruance SL

更新日期：1985-07-01 00:00:00

abstract：:We developed an immunoperoxidase staining test to detect structural antigens of BK virus (BKV) in Vero cell cultures. This test was used to examine the neutralizing activity of human and immunized animal sera. It was shown that sera positive for BKV antibodies measured by hemagglutination inhibition test and enzyme-li...

journal_title：Journal of medical virology

authors： Flaegstad T,Traavik T,Christie KE,Joergensen J

更新日期：1986-07-01 00:00:00

abstract：:The coronavirus disease 2019 (COVID-19) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) began in December 2019 and was basically under control in April 2020 in Wuhan. To explore the impact of intervention measures on the COVID-19 epidemic, we established susceptible-exposed-infectious-r...

journal_title：Journal of medical virology

authors： Li M,Guo X,Wang X

更新日期：2021-01-07 00:00:00