Congenital and perinatal infection with Junin virus in guinea pigs.

abstract：:In early 2008, a sudden increase in oseltamivir (Tamiflu)-resistant influenza A H1N1 viruses was reported from several European countries. This resistant virus has spread globally and accounted for more than 95% of H1N1 viruses isolated in the following influenza season. A continuous close monitoring on the prevalence...

journal_title：Journal of medical virology

authors： Ngai KL,Lam WY,Lee N,Leung TF,Hui DS,Chan PK

更新日期：2010-08-01 00:00:00

abstract：:Genotype 1F was likely localized geographically to China as it has not been reported elsewhere. In this study, whole genome sequences of two rubella 1F virus isolates were completed. Both viruses contained 9,761 nt with a single nucleotide deletion in the intergenic region, compared to the NCBI rubella reference seque...

journal_title：Journal of medical virology

authors： Zhu Z,Chen MH,Abernathy E,Zhou S,Wang C,Icenogle J,Xu W

更新日期：2014-12-01 00:00:00

abstract：:Serum samples from 87 patients with hepatocellular carcinoma (HCC) in the United States were tested for evidence of hepatitis C viral (HCV) infection using an immunoblot assay for antibodies to the hepatitis C virus and the polymerase chain reaction to detect HCV RNA. The findings with these assays were compared to th...

journal_title：Journal of medical virology

authors： Mangia A,Vallari DS,Di Bisceglie AM

更新日期：1994-06-01 00:00:00

abstract：:Hepatitis E virus sequences were detected by RT-PCR in 14/15 (93%) of untreated sewage samples from Edinburgh, Scotland, UK. Phylogenetic analysis of amplicons at limiting dilution revealed the co-circulation of multiple variants of HEV-3, with a pattern of diversity matching that observed in a local cohort of HEV-inf...

journal_title：Journal of medical virology

authors： Smith DB,Paddy JO,Simmonds P

更新日期：2016-05-01 00:00:00

abstract：:Despite prolonged undetectable plasma viral load some HIV-1 infected patients have been reported to develop resistance-associated mutations leading to treatment failure. The mechanisms for this phenomenon and the point of origin for residual viral evolution are still not elucidated. In order to quantify cell-associate...

journal_title：Journal of medical virology

authors： Kupfer B,Matz B,Däumer MP,Roden F,Rockstroh JK,Qurishi N,Spengler U,Kaiser R

更新日期：2007-10-01 00:00:00

abstract：:The objective of this study was to investigate variation in human papillomavirus (HPV) type-16 load within histologically defined grades of cervical intraepithelial neoplasia. Two hundred and thirty-seven liquid based cytology samples were collected from women attending colposcopy clinics, DNA was extracted, and prese...

journal_title：Journal of medical virology

authors： Fiander AN,Hart KW,Hibbitts SJ,Rieck GC,Tristram AJ,Beukenholdt RW,Powell NG

更新日期：2007-09-01 00:00:00

abstract：:SARS-CoV-2 infection is causing a pandemic disease that is reflected in challenging public health problems worldwide. Human leukocyte antigen (HLA)-based epitope prediction and its association with disease outcomes provide an important base for treatment design. A bioinformatic prediction of T cell epitopes and their ...

journal_title：Journal of medical virology

authors： Romero-López JP,Carnalla-Cortés M,Pacheco-Olvera DL,Ocampo-Godínez JM,Oliva-Ramírez J,Moreno-Manjón J,Bernal-Alferes B,López-Olmedo N,García-Latorre E,Domínguez-López ML,Reyes-Sandoval A,Jiménez-Zamudio L

更新日期：2020-09-28 00:00:00

abstract：:Recent years have seen a high incidence of mumps, which is generally diagnosed based on clinical features, especially parotitis, without laboratory confirmation in Korea. To better understand the epidemiology of mumps in Korean children, we investigated sporadic suspected mumps cases with parotitis. In total, 237 bucc...

journal_title：Journal of medical virology

authors： Kang HJ,Kim SH,Chung JK,Lee SW,Choi SB,Eom HE,Park O,Kim K,Kim SS

更新日期：2018-01-01 00:00:00

abstract：:Herpes simplex virus (HSV)-specific IgG and IgA antibody response in patients with HSV infection and in healthy adults was studied by the immunoperoxidase antibody-membrane antigen (IPAMA) technique. In all HSV infections in which specific IgM antibodies were detected by enzyme-linked immunosorbent assay (ELISA), a si...

journal_title：Journal of medical virology

authors： Hadar T,Sarov I

更新日期：1984-01-01 00:00:00

abstract：:Crimean-Congo hemorrhagic fever (CCHF) is an infectious disease that is caused by CCHF virus. A family of transmembrane receptors called as Toll-like receptors (TLRs) selectively acts in recognizing a wide range of microbial components and endogenous molecules released by damaged tissue and have been preserved through...

journal_title：Journal of medical virology

authors： Engin A,Arslan S,Özbilüm N,Bakir M

更新日期：2016-10-01 00:00:00

abstract：:Although the haemagglutination inhibition assay is considered the "gold standard" for antigenic characterisation of influenza viruses, some limitations of this technique are well known. A new microneutralisation assay, as a tool for antigenic characterisation of influenza B viruses, has been standardised and its perfo...

journal_title：Journal of medical virology

authors： Ansaldi F,Bacilieri S,Amicizia D,Valle L,Banfi F,Durando P,Sticchi L,Gasparini R,Icardi G,Crovari P

更新日期：2004-09-01 00:00:00

abstract：:HIV diagnosis at the point-of-care or in resource-limited settings poses considerable challenges due to time and cost limitations. Currently, nucleic acid-based tests are the only reliable method for diagnosing recent infections during the window period post-infection and pre-seroconversion, but these tests are only s...

journal_title：Journal of medical virology

authors： Curtis KA,Rudolph DL,Owen SM

更新日期：2009-06-01 00:00:00

abstract：:An outbreak of dengue type 2 occurred in North Queensland, Australia, between December 1996 and April 1997. Culture of serum in the Aedes albopictus C6/36 cell line with detection using immunofluorescent staining was compared with a culture-amplified detection system using an immunoperoxidase staining method in a micr...

journal_title：Journal of medical virology

authors： Gleeson F,McBride J,Norton R

更新日期：1999-02-01 00:00:00

abstract：:Twenty marmosets, male Callithrix jacchus, were used during this study. Fifteen of the marmosets were inoculated with 5,000 TCID50 of the attenuated XJC13 strain of Junin virus by intramuscular route and five were left as uninoculated controls. Animals were observed for a 420-day period. In order to carry out virologi...

journal_title：Journal of medical virology

authors： Avila MM,Frigerio MJ,Weber EL,Rondinone S,Samoilovich SR,Laguens RP,de Guerrero LB,Weissenbacher MC

更新日期：1985-01-01 00:00:00

abstract：:The efficacy of interferon (IFN) monotherapy for non-responders to pegylated interferon (PEG-IFN) plus ribavirin (RBV) combination therapy is still unclear. To evaluate the impact of IFN monotherapy on biochemical response, 200 consecutive patients infected with HCV genotype 1b, who received low-dose intermittent IFN-...

journal_title：Journal of medical virology

authors： Akuta N,Suzuki F,Kawamura Y,Yatsuji H,Sezaki H,Suzuki Y,Hosaka T,Kobayashi M,Kobayashi M,Arase Y,Ikeda K,Kumada H

更新日期：2008-08-01 00:00:00

abstract：:Co-infection with hepatitis delta virus (HDV) and hepatitis B virus (HBV) has been shown to be associated with a more severe form of acute and chronic hepatitis. Cloning and expression of recombinant HDV antigen (rHDAg) in Escherichiacoli are described. Using purified rHDAg, a cost-effective indirect anti-HDV enzyme-l...

journal_title：Journal of medical virology

authors： Shen L,Gu Y,Sun L,Yang Y,Wang F,Li Y,Bi S

更新日期：2012-03-01 00:00:00

abstract：:In real-world settings, not much information is probably available on the treatment efficacy of the combination of glecaprevir and pibrentasvir (G/P) as a salvage therapy in failures of prior direct-acting antiviral (DAA) regimens. Especially, the evolution of NS5A resistance-associated variants (RAVs) and treatment e...

journal_title：Journal of medical virology

authors： Akuta N,Sezaki H,Suzuki F,Fujiyama S,Kawamura Y,Hosaka T,Kobayashi M,Kobayashi M,Saitoh S,Suzuki Y,Arase Y,Ikeda K,Kumada H

更新日期：2019-01-01 00:00:00

abstract：:ZIKV infection has become a global threat spreading across 31 countries in Central America, South America, and the Caribbean. However, little information is available about the molecular epidemiology of ZIKV. Shared mutation of a threonine residue to alanine at the same position in the C terminal of NS5 sequences was ...

journal_title：Journal of medical virology

authors： Adiga R

更新日期：2016-10-01 00:00:00

abstract：:Noroviruses (NoV) and sapoviruses (SaV) are recognized as important causes of acute gastroenteritis in children worldwide. In this study, the prevalence and genetic variability of NoV and SaV were determined in hospitalized children <5 years of age with acute gastroenteritis in Hanoi, Vietnam. A total of 501 fecal spe...

journal_title：Journal of medical virology

authors： Trang NV,Luan le T,Kim-Anh le T,Hau VT,Nhung le TH,Phasuk P,Setrabutr O,Shirley H,Vinjé J,Anh DD,Mason CJ

更新日期：2012-02-01 00:00:00

abstract：:The effects of tumor necrosis factor-alpha and/or interferon-gamma on the replication of hepatitis B virus were examined using HB611 cells. These cells were derived from human hepatoblastoma cells, Huh6, by integrating hepatitis B virus DNA, and produce hepatitis B virus continuously. Each of the cytokines inhibited h...

journal_title：Journal of medical virology

authors： Kawanishi Y,Hayashi N,Katayama K,Ueda K,Takehara T,Miyoshi E,Mita E,Kasahara A,Fusamoto H,Kamada T

更新日期：1995-11-01 00:00:00

abstract：:The nucleotide sequences of the precore/core and X open reading frames (ORFs) of hepatitis B virus (HBV) were studied in four subjects who were serologically negative for anti-hepatitis B core antibody. These subjects were positive for serum hepatitis B surface antigen and were considered to be asymptomatic HBV carrie...

journal_title：Journal of medical virology

authors： Gotoh K,Mima S,Uchida T,Shikata T,Yoshizawa K,Irie M,Mizui M

更新日期：1995-07-01 00:00:00

abstract：:Human metapneumovirus, with two known genotypes named A and B, is associated with mild respiratory symptoms to severe LRTI in children, high-risk adults and the elderly. Rapid and reliable methods of hMPV detection in clinical samples are essential to implement appropriate care, to better understand the pathology of h...

journal_title：Journal of medical virology

authors： Manoha C,Bour JB,Pitoiset C,Darniot M,Aho S,Pothier P

更新日期：2008-01-01 00:00:00

abstract：:The discovery of acyclovir marked the beginning of an exciting era in antiviral research. Early studies on the novel mode of action explained the selectivity of the compound and the remarkably narrow spectrum of activity against a subset of the herpesviruses. Throughout the past decade many clinical trials have demons...

journal_title：Journal of medical virology

authors： Darby G

更新日期：1993-01-01 00:00:00

abstract：:Human T-cell lymphotropic virus (HTLV) antibody screening is not recommended uniformly before transplantation in Western countries. In the year 2001, the first cases of HTLV-I infection acquired through organ transplantation from one asymptomatic carrier were reported in Europe. All three organ recipients developed a ...

journal_title：Journal of medical virology

authors： Toro C,Benito R,Aguilera A,Bassani S,Rodríguez C,Calderón E,Caballero E,Alvarez P,García J,Rodríguez-Iglesias M,Guelar A,del Romero J,Soriano V,HTLV Spanish Study Group.

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND AND AIM:The hepatitis B virus (HBV) prevalence study performed in 2003 in Belgium is believed to be underestimating HBV prevalence due to underrepresentation of the non-Belgian population. Therefore, we assessed the prevalence and risk factors of HBV infection in a multi-ethnic region situated in Middle-Limb...

journal_title：Journal of medical virology

authors： Koc ÖM,Kremer C,Bielen R,Buscchots D,Hens N,Nevens F,Robaeys G

更新日期：2019-08-01 00:00:00

abstract：:A molecular epidemiological study on common diarrheal viruses was conducted in Ho Chi Minh City, Vietnam between October 2002 and September 2003. Fecal samples were collected from 1,010 hospitalized children with acute gastroenteritis. Those samples were screened for groups A, B, and C rotavirus, adenovirus, genogroup...

journal_title：Journal of medical virology

authors： Nguyen TA,Yagyu F,Okame M,Phan TG,Trinh QD,Yan H,Hoang KT,Cao AT,Le Hoang P,Okitsu S,Ushijima H

更新日期：2007-05-01 00:00:00

abstract：:Chronic hepatitis B patients with low pre-treatment HBeAg (and HBV-DNA) levels are more likely to respond to interferon-alpha therapy. In retrospect, this low level of HBeAg may have been reached just before the start of therapy. Pre-treatment changes in HBeAg levels were studied in 121 patients undergoing interferon-...

journal_title：Journal of medical virology

authors： Heijtink RA,Janssen HL,Hop WC,Osterhaus AD,Schalm SW

更新日期：2001-03-01 00:00:00

abstract：:The study characterized the virological patterns and the resistance-associated substitutions (RASs) in patients with failure to IFN-free regimens enrolled in the real-life setting. All 87 consecutive HCV patients with failed IFN-free regimens, observed at the laboratory of the University of Campania, were enrolled. Al...

journal_title：Journal of medical virology

authors： Starace M,Minichini C,De Pascalis S,Macera M,Occhiello L,Messina V,Sangiovanni V,Adinolfi LE,Claar E,Precone D,Stornaiuolo G,Stanzione M,Ascione T,Caroprese M,Zampino R,Parrilli G,Gentile I,Brancaccio G,Iovinella V,

更新日期：2018-05-01 00:00:00

abstract：:Hepatitis C virus (HCV) genotypes help to tailor the treatment response, but their influence on the disease severity and association with hepatic steatosis is not well understood. The prevalence of HCV genotypes and their correlation with the histopathological severity of liver disease and steatosis in Indian patients...

journal_title：Journal of medical virology

authors： Hissar SS,Goyal A,Kumar M,Pandey C,Suneetha PV,Sood A,Midha V,Sakhuja P,Malhotra V,Sarin SK

更新日期：2006-04-01 00:00:00

abstract：:Paired serum and saliva samples were tested by enzyme-linked immunosorbent assay (ELISA) and Western blot (WB) for the presence of human immunodeficiency virus (HIV) antibodies. The study group included 36 individuals known to be HIV seropositive and 14 healthy, seronegative controls. HIV antibodies were detected in a...

journal_title：Journal of medical virology

authors： Holmström P,Syrjänen S,Laine P,Valle SL,Suni J

更新日期：1990-04-01 00:00:00