Abstract:
:Human T-cell lymphotropic virus (HTLV) antibody screening is not recommended uniformly before transplantation in Western countries. In the year 2001, the first cases of HTLV-I infection acquired through organ transplantation from one asymptomatic carrier were reported in Europe. All three organ recipients developed a subacute myelopathy shortly after transplantation. This report rose the question about whether to implement universal anti-HTLV screening of all organ donors or selective screening of donors from endemic areas for HTLV-I infection should be carried out. A national survey was conducted thereafter in which anti-HTLV antibodies were tested in 1,298 organ transplant donors and 493 potential recipients. None was seropositive for HTLV-I and only one recipient, a former intravenous (i.v.) drug user, was found to be infected with HTLV-II. In a different survey, HTLV screening was conducted in 1,079 immigrants and 5 (0.5%) were found to be asymptomatic HTLV-I carriers. All came from endemic areas for HTLV-I infection. No cases of HTLV-II infection were found among immigrants. These results support the current policy of mandatory testing of anti-HTLV antibodies in Spain only among organ transplant donors coming from HTLV-I endemic areas or with a highly suspicion of HTLV-I infection.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Toro C,Benito R,Aguilera A,Bassani S,Rodríguez C,Calderón E,Caballero E,Alvarez P,García J,Rodríguez-Iglesias M,Guelar A,del Romero J,Soriano V,HTLV Spanish Study Group.doi
10.1002/jmv.20331keywords:
subject
Has Abstractpub_date
2005-06-01 00:00:00pages
268-70issue
2eissn
0146-6615issn
1096-9071journal_volume
76pub_type
杂志文章abstract::HIV is among the most generically variable of human pathogens. A comprehensive and detailed description of HIV strains in the pandemic is an important foundation for diagnosis, treatment, and prevention. The current sequence database for HIV includes almost 800 complete genome sequences, documenting HIV-1 groups M, O,...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20599
更新日期:2006-01-01 00:00:00
abstract::Human herpes virus type 6 (HHV-6) infection is widespread in healthy individuals. The only definite disease association is with exanthem subitum in infants though the virus has been linked with a variety of other diseases including interstitial pneumonitis in bone marrow allograft recipients. In order to investigate t...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890410204
更新日期:1993-10-01 00:00:00
abstract::A sensitive and reproducible real-time PCR assay based on TaqMan technology was developed for the detection and quantitation of hepatitis B virus (HBV) DNA in serum, and compared with an "in-house" qualitative PCR assay. HBV DNA was measured in 125 serum samples from 76 hepatitis B patients, consisting of 22 patients ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.2027
更新日期:2001-10-01 00:00:00
abstract::There is an obvious concern globally regarding the fact about the emerging coronavirus 2019 novel coronavirus (2019-nCoV) as a worldwide public health threat. As the outbreak of COVID-19 causes by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) progresses within China and beyond, rapidly available epi...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.25743
更新日期:2020-06-01 00:00:00
abstract::With virus-infected autologous and allogenic mononuclear cells as specific targets, the development of cell-mediated cytotoxic reactivity to respiratory syncytial virus (RSV) was studied in peripheral blood lymphocytes (PBL) in groups of infants with acute RSV infection and in other control groups of subjects during a...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890280304
更新日期:1989-07-01 00:00:00
abstract::Hepatitis C virus (HCV) virions have been shown to be bound to antibodies in patients with chronic HCV infection. The sera from patients infected with genotype 1b HCV contained more antibody-free virions than those from patients with genotype 2a/2b HCV. When compared at the same levels of serum HCV RNA, free virion ti...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:2000-05-01 00:00:00
abstract::Poliovirus (PV) is a member of the species Enterovirus C (EV-C), which may cause irreversible paralysis and death. So, for the purpose of analyzing the evolution of PV2 to help in eradicating PVs globally, a recombination analysis was performed to verify all viral genomes of EV-C, and we found 13 putative recombinatio...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.25620
更新日期:2020-03-01 00:00:00
abstract::Because in situ/filter hybridisation is not sensitive enough and because classical polymerase chain reaction (PCR) protocols are generally not sufficiently reproducible and specific, there is little accurate information on the prevalence of human papillomaviruses (HPV) 16, 18, and 33 infections in women without dyskar...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890360409
更新日期:1992-04-01 00:00:00
abstract::Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) have similar transmission routes, implying that patients infected with HIV are at particular risk for HBV infection. Patients who are co-infected with HIV and HBV progress more rapidly to end-stage liver disease and different HBV genotypes may have a disti...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22174
更新日期:2011-11-01 00:00:00
abstract::The Markov model was introduced to simulate natural histories of hepatitis C virus (HCV) infection in men and women. The data set was constructed on 942 HCV carriers who were examined at least once a year without receiving antiviral therapies. Based on 2,251 patient-year data, the probabilities of transition between a...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.10406
更新日期:2003-07-01 00:00:00
abstract::Subviral particles of hepatitis B virus have been used to present foreign epitopes. We attempted to present the hydrophilic domains of E2 envelope protein of hepatitis C virus (HCV) as a fusion protein with hepatitis B virus surface antigen (HBsAg). The five hydrophilic domains of HCV E2 antigen were inserted into HBs...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(SICI)1096-9071(199610)50:2<145::AID-JMV7>
更新日期:1996-10-01 00:00:00
abstract::The 30-base pair (bp) deletion of the cytoplasmic carboxy-terminal domain of the latent membrane protein 1 (LMP-1) gene was analyzed in 37 frozen tissues from patients with Epstein-Barr virus (EBV)-related gastric cancer and 18 throat washings from healthy adults in southern Japan. The 30-bp deletion was identified in...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9071(199902)57:2<152::aid-jmv11
更新日期:1999-02-01 00:00:00
abstract::Patterns of endemicity of human herpesvirus 8 (HHV8) are still undefined in some European populations, such as those from Western Balkan countries. Serum samples from 605 human immunodeficiency virus-seronegative subjects (299 Albanians and 306 Kosovars) were tested for the presence of HHV8 antibodies to a capsid-rela...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20644
更新日期:2006-07-01 00:00:00
abstract::Since outbreaks of severe acute hemorrhagic conjunctivitis occur worldwide [Hierholzer and Hatch, 1985] and the majority of the epidemics are caused by enterovirus 70 (EV-70), we developed an EV-70 IgM ELISA to simplify the diagnosis of these outbreaks. The test is based on the capture antibody technique and the use o...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890210404
更新日期:1987-04-01 00:00:00
abstract::Five HIV-1 isolates were obtained sequentially from a single seropositive individual during the later stages of AIDS. Four of these isolates were adapted to grow in a continuous human T-lymphocytic cell line. Comparative biological and biochemical studies of the virus isolates were made using persistently infected cul...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890340207
更新日期:1991-06-01 00:00:00
abstract::Enteroviruses (EVs) are RNA viruses that can cause many clinical syndromes including acute flaccid paralysis (AFP). Within the global polio laboratory network, EVs are categorized either as polioviruses or non-polio enteroviruses (NPEVs). Specific NPEVs have been described in polio-like residual paralytic events in AF...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26804
更新日期:2021-01-17 00:00:00
abstract::Cytomegalovirus-specific complement-fixing IgM (CMV CF-IgM) antibody was detected in 12/84 (14.3 percent) sera containing CMV-specific IgM. Higher titres were obtained by using a purified antigen preparation containing enveloped virus particles and membrane fragments when compared with a crude extract of infected cell...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890240312
更新日期:1988-03-01 00:00:00
abstract::Mitochondrial DNA (mtDNA) of peripheral blood mononuclear cells (PBMCs) collected from Human immunodeficiency virus 1 (HIV-1)-infected patients and healthy controls were measured longitudinally using real-time polymerase chain reaction to evaluate the effects of antiretroviral agents on mtDNA synthesis in vivo and to ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.10423
更新日期:2003-08-01 00:00:00
abstract::HIV excretion patterns and specific antibody responses were evaluated in blood, semen, female genital secretions, saliva, and crevicular fluid. Samples were examined for infectious virus, viral antigens, viral nucleic acid, HIV specific IgG, IgA, anti-nef, and anti-p24. Viral load in peripheral blood appeared to incre...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890310409
更新日期:1990-08-01 00:00:00
abstract::The aetiological agents responsible for, and the outcome of, acute liver failure were investigated prospectively in 44 children (29 males, 15 females) attending a tertiary health care facility in India. The children were between the ages of 2 months and 13 years. Studies for viral infections and other etiologies could...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(SICI)1096-9071(199603)48:3<215::AID-JMV1>
更新日期:1996-03-01 00:00:00
abstract::HIV-1 infections due to non-B subtypes are increasing rapidly in number and spreading across Europe. The genetic nature of HIV-1 non-B variants containing subtype G sequences at the protease (PR)-coding region are described from 48 unrelated subjects living in Spain. Phylogenetic analyses of the HIV-1 reverse transcri...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20280
更新日期:2005-03-01 00:00:00
abstract::Immunoglobulin class-specific determination by ELISA and a virus neutralization test (NT) were compared for the detection of the serum antibody responses after vaccination of infants with the RIT 4237 rotavirus vaccine (of bovine origin). A capture method was applied for specific IgM determination by ELISA because of ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890210306
更新日期:1987-03-01 00:00:00
abstract::The TD97 strain vaccine virus was prepared from the Tanabe strain measles virus by low-temperature passages in primary cell cultures and ultraviolet (UV) mutagenesis. The TD97 strain exhibited the following characteristics: highly temperature sensitive, neither multiplying nor forming any plaques at 40 degrees C in Ve...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890320311
更新日期:1990-11-01 00:00:00
abstract::Respiratory syncytial (RSV) and parainfluenza (PIV) viruses are primary causes of acute bronchiolitis and wheezing illnesses in infants and young children. To further understand inflammation in the airways following infection, we tested for the presence of matrix metalloproteinases (MMP) and natural tissue inhibitors ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20830
更新日期:2007-04-01 00:00:00
abstract::The genotypes and subtypes of 205 HBV isolates collected during 1989-2002 in Estonia and 14 other regions of the former USSR were determined by sequencing and phylogenetic analysis of the S gene. The in Europe prevailing genotypes, A and D, were also circulating in the whole territory of the former USSR including Esto...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20169
更新日期:2004-10-01 00:00:00
abstract::BK polyomavirus (BKV) is a ubiquitous virus in humans that remains latent in the urogenital tract after a primary infection during childhood. The virus, which is reactivated frequently and excreted in urine, can cause nephropathy in renal transplant recipients. BKV sequences are classified into four subtypes (I-IV). S...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22035
更新日期:2011-04-01 00:00:00
abstract::Genotype-specific effects of parvovirus B19 (B19V) infections on left ventricular function in patients with dilated cardiomyopathy (DCM) have not been investigated so far. In this prospective clinical study, the prevalences of B19V genotypes in endomyocardial biopsies from patients presenting with inflammatory heart d...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22187
更新日期:2011-10-01 00:00:00
abstract::The aim of this study was to compare the data obtained using the new LIAISON® XL chemiluminescence system to search for HBsAg, anti-HCV, and anti-HIV1-2/p24 Ag with those obtained using the VITROS system currently adopted by the Microbiology Unit of the Hospital of Legnano. Routine samples of patients who were referre...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24648
更新日期:2017-03-01 00:00:00
abstract::Phleboviruses are a large and widespread group of viruses that are transmitted by arthropods. Toscana virus is one of the principal agents that causes meningitis in humans during the summer in Italy and, possibly, in other Mediterranean countries. Rift Valley Fever virus can cause serious illness in both animals and h...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.10465
更新日期:2003-09-01 00:00:00
abstract::Hepatitis C virus (HCV) exposure in blood donors is determined serologically by the detection of anti-HCV antibodies in serum or plasma. However, a "window" period of 30-70 days after exposure exists where specific antibodies to HCV antigens are not detected. The use of nucleic acid testing for the detection of HCV RN...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20716
更新日期:2006-11-01 00:00:00