Detection and identification of Toscana and other phleboviruses by RT-nested-PCR assays with degenerated primers.

abstract：:Five HIV-1 isolates were obtained sequentially from a single seropositive individual during the later stages of AIDS. Four of these isolates were adapted to grow in a continuous human T-lymphocytic cell line. Comparative biological and biochemical studies of the virus isolates were made using persistently infected cul...

journal_title：Journal of medical virology

authors： Farrar GH,Roff MA,Amin T,Ball J,Parrett AM,Battacharyya U,Booth J,Wansbrough-Jones MH,Greenaway PJ

更新日期：1991-06-01 00:00:00

abstract：:Foscarnet (trisodium phosphonoformate) is a novel antiviral agent that inhibits viral-specific DNA polymerase. In the present study, eight males with chronic HBV carriage (HBeAg and HBV-DNA seropositivity greater than 12 months) showing chronic persistent hepatitis (CPH) or chronic active hepatitis (CAH) on liver biop...

journal_title：Journal of medical virology

authors： Bain VG,Daniels HM,Chanas A,Alexander GJ,Williams R

更新日期：1989-10-01 00:00:00

abstract：:The temporal distribution and clinical severity of rotavirus VP7 serotypes 1, 2, 3, and 4 recovered from 427 Venezuelan children with acute gastroenteritis over a period of 11 years were studied. Rotavirus VP7 serotype was established by ELISA serotyping in 298 (69.78%) of the specimens while the serotype of the remai...

journal_title：Journal of medical virology

authors： White L,García D,Boher Y,Blanco M,Pérez M,Romer H,Flores J,Pérez-Schael I

更新日期：1991-06-01 00:00:00

abstract：:Hepatitis C virus (HCV) particles can be classified into two major fractions according to their floating density in serum. However, the genomic heterogeneity of each fraction and the relationship between this viral characteristic and interferon (IFN) response in patients with chronic hepatitis are not known. In this s...

journal_title：Journal of medical virology

authors： Sakai A,Kaneko S,Matsushita E,Kobayashi K

更新日期：1998-05-01 00:00:00

abstract：:The polymerase chain reaction (RNA-PCR) was used for specific detection of respiratory syncytial virus (RSV) genomes in clinical specimens. A set of primers was selected from conserved regions of the 1B and N genes for detection of both subgroups. The primers were found to be RSV specific, all RSV strains generated a ...

journal_title：Journal of medical virology

authors： van Milaan AJ,Sprenger MJ,Rothbarth PH,Brandenburg AH,Masurel N,Claas EC

更新日期：1994-09-01 00:00:00

abstract：:Recent studies have shown an association between single nucleotide polymorphisms (SNPs) in the interferon lambda-3 (IFNL3 or IL-28B) and IFNL4 genes and treatment response to hepatitis C virus genotype 1 (HCV-1) infection. The importance of these SNPs for HCV genotype 3 (HCV-3), and particularly HCV genotype 6 (HCV-6)...

journal_title：Journal of medical virology

authors： Akkarathamrongsin S,Thong VD,Payungporn S,Poovorawan K,Prapunwattana P,Poovorawan Y,Tangkijvanich P

更新日期：2014-09-01 00:00:00

abstract：:The human parvovirus B19 (B19) usually causes a subclinical infection in immunocompetent individuals. Whereas immunocompromised individuals such as patients infected with HIV are at risk of persistent anemia due to B19 infection. Only few studies have been carried out on distribution and molecular epidemiology of B19 ...

journal_title：Journal of medical virology

authors： Azadmanesh K,Mohraz M,Kazemimanesh M,Aghakhani A,Foroughi M,Banifazl M,Eslamifar A,Ramezani A

更新日期：2015-07-01 00:00:00

abstract：:Seoul virus (SEOV) is the etiologic agent of hemorrhagic fever with renal syndrome. It is carried by brown rats (Rattus norvegicus), a commensal rodent that closely cohabitates with humans in urban environments. SEOV has a worldwide distribution, and in Europe, it has been found in rats in UK, France, Sweden, and Belg...

journal_title：Journal of medical virology

authors： Ling J,Verner-Carlsson J,Eriksson P,Plyusnina A,Löhmus M,Järhult JD,van de Goot F,Plyusnin A,Lundkvist Å,Sironen T

更新日期：2019-05-01 00:00:00

abstract：:The role of Epstein-Barr virus (EBV) in the pathogenesis of gastric lymphoma of mucosa-associated lymphoid tissue (MALT) has not been well understood. The aim of the study was to investigate EBV infection and its gene expression in this tumor in order to understand its role in the pathogenesis. EBV infection was scree...

journal_title：Journal of medical virology

authors： Xu WS,Chan AC,Lee JM,Liang RH,Ho FC,Srivastava G

更新日期：1998-12-01 00:00:00

abstract：:Because in situ/filter hybridisation is not sensitive enough and because classical polymerase chain reaction (PCR) protocols are generally not sufficiently reproducible and specific, there is little accurate information on the prevalence of human papillomaviruses (HPV) 16, 18, and 33 infections in women without dyskar...

journal_title：Journal of medical virology

authors： Vandenvelde C,Scheen R,Van Pachterbeke C,Loriaux C,Decelle J,Hubert T,Delhaye C,Cattoor JP,Duys M,Van Beers D

更新日期：1992-04-01 00:00:00

abstract：:Studies of hepatitis B virus (HBV) infection in non-human primates such as chimpanzees are no longer possible due to ethical considerations and the endangered status of chimpanzees since April 2007 in Japan. A human hepatocyte transplanted chimeric mouse was used to characterize HBV infectivity in serial stages of acu...

journal_title：Journal of medical virology

authors： Tabuchi A,Tanaka J,Katayama K,Mizui M,Matsukura H,Yugi H,Shimada T,Miyakawa Y,Yoshizawa H

更新日期：2008-12-01 00:00:00

abstract：:Comparison of RT-PCR assays established in house at various places revealed that laboratories could differ in sensitivity by as much as 1,000-fold in terms of the ability to detect measles virus sequences in clinical samples. The study indicates that PCR findings, positive or negative, are questionable if they are not...

journal_title：Journal of medical virology

authors： Afzal MA,Osterhaus AD,Cosby SL,Jin L,Beeler J,Takeuchi K,Kawashima H

更新日期：2003-05-01 00:00:00

abstract：:The severe acute respiratory syndrome (SARS) leads to severe injury in the lungs with multiple factors, though the pathogenesis is still largely unclear. This paper describes the particular analyses of the transcriptome of human lung tissue that was infected by SARS-associated coronavirus (SARS-CoV). Random primers we...

journal_title：Journal of medical virology

authors： Wu H,Wang J,Deng R,Xing K,Xiong Y,Huang J,He X,Wang X

更新日期：2011-04-01 00:00:00

abstract：:In the ongoing coronavirus disease 2019 (COVID-19) pandemic, one potential cause of concern is that some discharged COVID-19 patients are testing positive again for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA. To better understand what is happening and to provide public health policy planners and ...

journal_title：Journal of medical virology

authors： Han Z,Battaglia F,Terlecky SR

更新日期：2020-07-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) and human T-cell lymphotropic virus (HTLV) are both retroviruses with similar routes of transmission. A number of reports suggest variable clinical outcomes in HIV and HTLV co-infected individuals. There is no published information regarding the prevalence of HIV and HTLV co-infectio...

journal_title：Journal of medical virology

authors： Cooke FJ,Geretti AM,Zuckerman M

更新日期：2005-06-01 00:00:00

abstract：:In April 2004, two patients were admitted to hospital in Berlin, Germany, with clinical signs of acute respiratory infection after returning from a military exercise in their home country of Turkey. They were admitted to a high security infectious disease unit as epidemiological data pointed to an outbreak of unknown ...

journal_title：Journal of medical virology

authors： Chmielewicz B,Benzler J,Pauli G,Krause G,Bergmann F,Schweiger B

更新日期：2005-10-01 00:00:00

abstract：:An attempt was made to identify factors influencing the cumulative probability of an increased alanine aminotransferase (ALT) level and hepatocarcinogenesis in hepatitis C patients with a normal ALT level initially. A total of 398 consecutive patients with a normal ALT level initially for 6 months or more and follow-u...

journal_title：Journal of medical virology

authors： Kumada T,Toyoda H,Kiriyama S,Sone Y,Tanikawa M,Hisanaga Y,Kanamori A,Atsumi H,Takagi M,Nakano S,Arakawa T,Fujimori M

更新日期：2009-03-01 00:00:00

abstract：:Herpesviruses produce assembly proteins (AP) that act as scaffolding proteins for the assembly of the viral capsids. The products of the assemblin gene, which encodes both maturational protease and AP, have been established for herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (CMV). We cloned an inframe O...

journal_title：Journal of medical virology

authors： Garcia-Valcarcel M,Fowler WJ,Harper DR,Jeffries DJ,Layton GT

更新日期：1997-12-01 00:00:00

abstract：:Persisting human papillomavirus (HPV) infection is a critical step in cervical carcinogenesis. This study was conducted to determine the type-specific HPV persistence and risk factors for persistence of high-risk HPV infections in a large cohort of Danish women. The study was based on a population-based prospective co...

journal_title：Journal of medical virology

authors： Nielsen A,Kjaer SK,Munk C,Osler M,Iftner T

更新日期：2010-04-01 00:00:00

abstract：:The role of T-cells in clearance of hepatitis C virus (HCV) during acute infection is critical. The relevance of the immunological response in the control of HCV replication is less clear in chronic HCV infection. HCV-specific T-cell responses were examined in 92 interferon-naive individuals with chronic hepatitis C. ...

journal_title：Journal of medical virology

authors： Capa L,Soriano V,García-Samaniego J,Nuñez M,Romero M,Cascajero A,Muñoz F,González-Lahoz J,Benito JM

更新日期：2007-05-01 00:00:00

abstract：:Hepatitis C virus (HCV) represents a major cause of posttransfusion hepatitis worldwide. Posttransfusion hepatitis associated with hepatitis B virus (HBV) continues to occur. HBsAg-negative donor sera from the Rhode Island Blood Center between 1987 and 1988 were screened using more sensitive techniques to assess the p...

journal_title：Journal of medical virology

authors： Liang TJ,Bodenheimer HC Jr,Yankee R,Brown NV,Chang K,Huang J,Wands JR

更新日期：1994-02-01 00:00:00

abstract：:Hepatitis B e antigen (HBeAg)-negative chronic hepatitis B results from infection with hepatitis B virus mutants unable to produce HBeAg. It accounts for 7-30% of patients with chronic hepatitis B virus (HBV) worldwide, with the highest rates reported for Mediterranean Europe and Asia. Interferon (IFN) is currently th...

journal_title：Journal of medical virology

authors： Rizzetto M

更新日期：2002-04-01 00:00:00

abstract：:Human herpesvirus 6 (HHV-6), the etiologic agent of roseola in young children, has been reported to be detectable in the brain of many neurologically normal adults, although regional localization to plaques of multiple sclerosis has also been demonstrated. Large amounts of this virus were present in multifocal demyeli...

journal_title：Journal of medical virology

authors： Novoa LJ,Nagra RM,Nakawatase T,Edwards-Lee T,Tourtellotte WW,Cornford ME

更新日期：1997-07-01 00:00:00

abstract：:Development of hepatitis B virus (HBV)-resistant strains following nucleos(t)ide analog treatment is a major medical concern. This report describes a case of an adult patient with chronic HBV infection, sequentially treated with the nucleos(t)ide analogues, lamivudine, adefovir, and entecavir. During monotherapy with ...

journal_title：Journal of medical virology

authors： Rodriguez-Frias F,Jardi R,Schaper M,Gimferrer M,Elefsiniotis I,Tabernero D,Esteban R,Buti M

更新日期：2007-11-01 00:00:00

abstract：:Recruitment of leukocytes by chemokines and chemokine receptors to CNS plays a crucial role in the induction of inflammatory response in HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). In the present study, chemokine and chemokine receptors involved in trafficking of lymphocytes to the CNS were me...

journal_title：Journal of medical virology

authors： Rafatpanah H,Felegari M,Azarpazhooh MR,Vakili R,Rajaei T,Hampson I,Hassanshahi G,Valizadeh N,Gerayli S,Hamid F,Zamanian S,MollaHosseini F,Rezaee SA

更新日期：2017-08-01 00:00:00

abstract：:To elucidate the role of host immune status in the evolution and complexity of hepatitis C virus (HCV) quasispecies, three chronic HCV-infected patients who underwent bone marrow transplantation (BMT) were studied. The three transplanted patients' sera were sampled at pre-BMT, 3 months after BMT, and 12 months after B...

journal_title：Journal of medical virology

authors： Ni YH,Chang MH,Chen PJ,Hsu HY,Lu TW,Lin KH,Lin DT

更新日期：1999-06-01 00:00:00

abstract：:Citrullinated histone H3 (H3Cit) is the product of the conversion of peptidylarginine to citrulline in histone H3. We evaluated the H3Cit level in hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) tissues and assessed its association with Beclin1 messenger RNA (mRNA) (a key autophagic regulator). The leve...

journal_title：Journal of medical virology

authors： Lu M,Zhang X,Xu Y,He G,Liu Q,Zhu J,Zhang C

更新日期：2020-08-01 00:00:00

abstract：:In order to demonstrate the viral specificity of IgM-containing immune complexes (IgM-CIC) detected by a C1q assay in renal allograft recipients developing a CMV infection, a technique is described allowing: 1) the dissociation of IgM-CIC by action of an acid buffer, and 2) the characterization of the viral specificit...

journal_title：Journal of medical virology

authors： Basson J,Tardy JC,Aymard M

更新日期：1991-03-01 00:00:00

abstract：:Neutralization of virus is likely to be necessary for development of an effective prophylactic vaccine against genital human papillomavirus (HPV) infection. Two New Zealand white rabbits were immunized with purified HPV type 11 (HPV 11) virions in Freund's adjuvant. An enzyme linked immunoassay (ELISA) was used to det...

journal_title：Journal of medical virology

authors： Bryan JT,Jansen KU,Lowe RS,Fife KH,McClowry T,Glass D,Brown DR

更新日期：1997-11-01 00:00:00

abstract：:A solution of pooled cryo-precipitate for preparing factor VIII (F VIII) by the solvent/detergent method was contaminated experimentally with parvovirus B19-positive plasma to evaluate virus reduction achieved by the final steps of the F VIII production process. Virus reduction was at least 2 logs of the total amount ...

journal_title：Journal of medical virology

authors： Schwarz TF,Roggendorf M,Hottenträger B,Stolz W,Schwinn H

更新日期：1991-09-01 00:00:00