IFNL3 (IL28B) and IFNL4 polymorphisms are associated with treatment response in Thai patients infected with HCV genotype 1, but not with genotypes 3 and 6.

abstract：:Adhesion molecules are essential for the immune response. They are involved in the regulation of cell-to-cell contact, thereby enabling leukocytes to communicate. Circulating forms of adhesion molecules are found in the serum of healthy individuals. Raised levels have been associated with disease severity in HCV and o...

journal_title：Journal of medical virology

authors： Murgue B,Cassar O,Deparis X

更新日期：2001-09-01 00:00:00

abstract：:Rotavirus vaccines have been available in Japan since 2011. This study conducted to monitor the trend of group A rotavirus (RVA) genotypes 3 years after vaccine introduction. A total of, 539 fecal samples were collected from children with acute gastroenteritis in six regions during July 2014-June 2015. Among them, 178...

journal_title：Journal of medical virology

authors： Khandoker N,Thongprachum A,Takanashi S,Okitsu S,Nishimura S,Kikuta H,Yamamoto A,Sugita K,Baba T,Kobayashi M,Hayakawa S,Mizuguchi M,Ushijima H

更新日期：2018-06-01 00:00:00

abstract：:A healthy patient presented to Klinikum Altmühlfranken Weißenburg Hospital, Germany, with two morning attacks of painful muscle spasm in the left upper and lower limbs, without altered consciousness. Full examinations, radiological imaging, electroencephalography, lumbar puncture, and autoimmune profile were either no...

journal_title：Journal of medical virology

authors： Elgamasy S,Kamel MG,Ghozy S,Khalil A,Morra ME,Islam SMS

更新日期：2020-10-01 00:00:00

abstract：:To evaluate the variation over time of seroreactivity to human papillomavirus type 11 (HPV-11) according to disease outcome, we selected a sample of 42 condyloma acuminatum patients from a group of subjects enrolled in a placebo-controlled trial of three alpha-interferon preparations administered parenterally for the ...

journal_title：Journal of medical virology

authors： Bonnez W,Da Rin C,Rose RC,Tyring SK,Reichman RC

更新日期：1993-04-01 00:00:00

abstract：:The aetiological agents responsible for, and the outcome of, acute liver failure were investigated prospectively in 44 children (29 males, 15 females) attending a tertiary health care facility in India. The children were between the ages of 2 months and 13 years. Studies for viral infections and other etiologies could...

journal_title：Journal of medical virology

authors： Arora NK,Nanda SK,Gulati S,Ansari IH,Chawla MK,Gupta SD,Panda SK

更新日期：1996-03-01 00:00:00

abstract：:Human metapneumovirus (hMPV) is considered an important cause of acute respiratory infections. hMPV can cause morbidity in hematopoietic stem cell transplant recipients and recent research has demonstrated that it is an important virus in patients admitted to hospital with respiratory infections and suspected of havin...

journal_title：Journal of medical virology

authors： Souza JS,Watanabe A,Carraro E,Granato C,Bellei N

更新日期：2013-03-01 00:00:00

abstract：:During Epstein-Barr virus (EBV) latency, the EBV genome is largely silenced by methylation. This silencing is overturned during the switch to the lytic cycle. A key event is the production of the viral protein Zta which binds to three Zta-response elements (ZRE) from the Rta promoter (Rp), two of which (ZRE2 and ZRE3)...

journal_title：Journal of medical virology

authors： Germi R,Guigue N,Lupo J,Semenova T,Grossi L,Vermeulen O,Epaulard O,de Fraipont F,Morand P

更新日期：2016-10-01 00:00:00

abstract：:The Balkan Peninsula and Bulgaria in particular, is a well-known endemic region for Crimean-Congo hemorrhagic fever (CCHF). This study describes the prevalence of Crimean-Congo hemorrhagic fever virus (CCHFV) among tick populations from areas, previously recognized with emerging cases of CCHF disease in humans. These ...

journal_title：Journal of medical virology

authors： Gergova I,Kunchev M,Kamarinchev B

更新日期：2012-04-01 00:00:00

abstract：:Hepatitis E virus sequences were detected by RT-PCR in 14/15 (93%) of untreated sewage samples from Edinburgh, Scotland, UK. Phylogenetic analysis of amplicons at limiting dilution revealed the co-circulation of multiple variants of HEV-3, with a pattern of diversity matching that observed in a local cohort of HEV-inf...

journal_title：Journal of medical virology

authors： Smith DB,Paddy JO,Simmonds P

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND AND AIM:Genotype 3b hepatitis C virus (HCV) infection represents approximately 50% of patients with genotype 3 in China. We compared the efficacy of sofosbuvir (SOF) plus ribavirin (RBV) in Chinese patients with genotype 3a and 3b HCV. METHODS:The analyzed data are from a phase 3, open-label study of SOF pl...

journal_title：Journal of medical virology

authors： Huang R,Rao H,Xie Q,Gao Z,Li W,Jiang D,Mo H,Massetto B,Stamm LM,Brainard DM,Wei L

更新日期：2019-07-01 00:00:00

abstract：:Studies of hepatitis B virus (HBV) infection in non-human primates such as chimpanzees are no longer possible due to ethical considerations and the endangered status of chimpanzees since April 2007 in Japan. A human hepatocyte transplanted chimeric mouse was used to characterize HBV infectivity in serial stages of acu...

journal_title：Journal of medical virology

authors： Tabuchi A,Tanaka J,Katayama K,Mizui M,Matsukura H,Yugi H,Shimada T,Miyakawa Y,Yoshizawa H

更新日期：2008-12-01 00:00:00

abstract：:The objectives of this study were to evaluate the reliability of herpes simplex virus (HSV) PCR testing in cerebrospinal fluid (CSF) for the detection of herpes simplex encephalitis. This was done by examining retrospectively the clinical follow-up of a large group of patients tested routinely by HSV-PCR. In addition,...

journal_title：Journal of medical virology

authors： Puchhammer-Stöckl E,Presterl E,Croÿ C,Aberle S,Popow-Kraupp T,Kundi M,Hofmann H,Wenninger U,Gödl I

更新日期：2001-08-01 00:00:00

abstract：:The presence of the E2 region of HPV 16 was determined by the polymerase chain reaction in biopsy samples with different histopathological diagnoses. The absence of the E2 gene was observed in 17 of 30 cases examined. The E2 deletions were not confined exclusively to invasive carcinomas or to integrated viral forms. I...

journal_title：Journal of medical virology

authors： Krajinovic M,Lazic J,Stanimirovic B,Diklic V,Savic A

更新日期：1993-09-01 00:00:00

abstract：:Dried blood spots collected on filter paper are considered potential clinical specimens for measles surveillance because of their ease of collection, storage, and transport. The usefulness of these samples for surveillance of measles was evaluated in a field setting. Blood spots were collected by finger-prick from 316...

journal_title：Journal of medical virology

authors： El Mubarak HS,Yüksel S,Mustafa OM,Ibrahim SA,Osterhaus AD,de Swart RL

更新日期：2004-08-01 00:00:00

abstract：:A pandemic of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection broke out all over the world; however, epidemiological data and viral shedding in pediatric patients are limited. We conducted a retrospective, multicenter study, and followed-up with all children from the families with SARS-CoV-2 inf...

journal_title：Journal of medical virology

authors： Hua CZ,Miao ZP,Zheng JS,Huang Q,Sun QF,Lu HP,Su FF,Wang WH,Huang LP,Chen DQ,Xu ZW,Ji LD,Zhang HP,Yang XW,Li MH,Mao YY,Ying MZ,Ye S,Shu Q,Chen EF,Liang JF,Wang W,Chen ZM,Li W,Fu JF

更新日期：2020-11-01 00:00:00

abstract：:A combined hepatitis A and B vaccine is available since 1996. Two separate open-label primary studies evaluated the immunogenicity and safety of this hepatitis A and B vaccine (720 EI.U of HAV and 20 µg of HBsAg) in 306 healthy subjects aged 17-43 years who received three doses of the vaccine following a 0, 1, and 6 m...

journal_title：Journal of medical virology

authors： Van Damme P,Leroux-Roels G,Crasta P,Messier M,Jacquet JM,Van Herck K

更新日期：2012-01-01 00:00:00

abstract：:Thirty susceptible rhesus monkeys were inoculated with cell-free varicella-zoster virus strain OKA or strain KMcC. Both wild and attenuated strains were used. No clinical signs characteristic of human varicella were seen in any of the animals. Virus was not isolated from throat swabs, blood, or cerebrospinal fluid. An...

journal_title：Journal of medical virology

authors： Asano Y,Albrecht P,Behr DE,Neff BJ,Vickers JH,Rastogi SC

更新日期：1984-01-01 00:00:00

abstract：:The TD97 strain vaccine virus was prepared from the Tanabe strain measles virus by low-temperature passages in primary cell cultures and ultraviolet (UV) mutagenesis. The TD97 strain exhibited the following characteristics: highly temperature sensitive, neither multiplying nor forming any plaques at 40 degrees C in Ve...

journal_title：Journal of medical virology

authors： Suzuki K,Morita M,Katoh M,Kidokoro M,Saika S,Yoshizawa S,Hashizume S,Horiuchi K,Okabe N,Shinozaki T

更新日期：1990-11-01 00:00:00

abstract：:Thirty-two cerebrospinal fluid (CSF) samples from eighteen patients with confirmed herpes simplex encephalitis (HSE) were assayed by an indirect enzyme-linked immunosorbent assay (ELISA) for the presence of viral antigens. The results are expressed as an antigen ratio distinguishing between herpes simplex virus (HSV) ...

journal_title：Journal of medical virology

authors： Bos CA,Olding-Stenkvist E,Wilterdink JB,Scheffer AJ

更新日期：1987-02-01 00:00:00

abstract：:The expression levels of many genes change after treatment of human immunodeficiency virus (HIV)-infected subjects by antiretroviral drugs. High-throughput analysis of tremendous datasets led to the discovery of genes that are implicated in the treatment pathways. In this study, we performed a gene-enrichment analysis...

journal_title：Journal of medical virology

authors： Mozhgani SH,Zarei Ghobadi M,Behnam Rad M,Farzanehpour M,Behzadian F

更新日期：2019-12-01 00:00:00

abstract：:Plenty of serologic tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been developed so far, thus documenting the importance of evaluating the relevant features of the immune response to this viral agent. The performance of these assays is currently under investigation. Amongst them, LIAISON®...

journal_title：Journal of medical virology

authors： Criscuolo E,Diotti RA,Strollo M,Rolla S,Ambrosi A,Locatelli M,Burioni R,Mancini N,Clementi M,Clementi N

更新日期：2020-10-16 00:00:00

abstract：:The specificity and neutralizing activity of antibodies against the major herpes simplex virus type 1 (HSV-1) glycoproteins were tested in serum samples of patients with a history of HSV-1 infection. By preabsorption of sera to preparations of native and denatured HSV-1 proteins, followed by immunoblotting and microne...

journal_title：Journal of medical virology

authors： Eing BR,Kühn JE,Braun RW

更新日期：1989-01-01 00:00:00

abstract：INTRODUCTION:Although the effectiveness of direct-acting antivirals (DAAs) for the treatment of chronic hepatitis C virus (HCV) has been reported in real-world settings, predictive factors of treatment failure are lacking. Therefore, we sought to explore the baseline predictors of treatment response to DAAs. METHODS:T...

journal_title：Journal of medical virology

authors： Ridruejo E,Piñero F,Mendizabal M,Cheinquer H,Wolff FH,Anders M,Reggiardo V,Ameigeiras B,Palazzo A,Alonso C,Schinoni MI,Zuain MGV,Tanno F,Figueroa S,Santos L,Peralta M,Soza A,Vistarini C,Adrover R,Fernández N,Perez

更新日期：2020-08-04 00:00:00

abstract：:Adenovirus infections are usually mild or even asymptomatic, but infections with the virus are being recognized increasingly as a major cause of mortality and morbidity in the immunocompromised, particularly hematological stem cell transplant patients where infections can be life threatening and mortality may reach 60...

journal_title：Journal of medical virology

authors： Al Qurashi YM,Guiver M,Cooper RJ

更新日期：2011-11-01 00:00:00

abstract：:Limited amount of information is available in Taiwan on the genetic or antigenic characteristics of influenza A virus prior to the establishment of a Taiwan surveillance network in 2000. Isolates of H1N1 and H3N2 viruses in Taiwan between 1980 and 2006 were studied, and part of the hemagglutinin gene was analyzed due ...

journal_title：Journal of medical virology

authors： Wang SF,Lee YM,Chan YJ,Liu HF,Yen YF,Liu WT,Huang JC,Chen YM

更新日期：2009-08-01 00:00:00

abstract：:To assess whether the administration of a booster dose of influenza vaccine may enhance immune response in hemodialysis patients, 58 subjects were given two doses of the 2003/2004 season influenza vaccine, 1 month apart. "European Agency for the Evaluation of Medicinal Products" (EMEA) criteria were fully met in terms...

journal_title：Journal of medical virology

authors： Tanzi E,Amendola A,Pariani E,Zappa A,Colzani D,Logias F,Perego A,Zanetti AR

更新日期：2007-08-01 00:00:00

abstract：:The seroprevalence of antibodies to hepatitis E virus (HEV) and hepatitis A virus (HAV) was determined in a community-based sample in innercity London where socioeconomic conditions were expected to result in a high prevalence of antibodies to HAV, and in which the presence of immigrants from the developing world pose...

journal_title：Journal of medical virology

authors： Bernal W,Smith HM,Williams R

更新日期：1996-07-01 00:00:00

abstract：:In patients infected with the hepatitis C virus (HCV), a heterogeneous population of viruses, so-called quasispecies exists in vivo. The hypervariable regions (HVR) within the second envelope gene (HCV-E2) show particularly highly intratypic variability and are considered to be the target of neutralizing antibodies. T...

journal_title：Journal of medical virology

authors： Lee JH,Stripf T,Roth WK,Zeuzem S

更新日期：1997-11-01 00:00:00

abstract：:Replication of HIV-1 inside host cells is dependent on both viral and host factors. MicroRNAs are small noncoding RNAs that regulate protein synthesis. MicroRNAs may control viral replication either by directly targeting the viral genome or indirectly through cellular proteins that are required during the viral lifecy...

journal_title：Journal of medical virology

authors： Dubey RC,Alam NB,Gaur R

更新日期：2020-12-24 00:00:00

abstract：:In order to demonstrate the viral specificity of IgM-containing immune complexes (IgM-CIC) detected by a C1q assay in renal allograft recipients developing a CMV infection, a technique is described allowing: 1) the dissociation of IgM-CIC by action of an acid buffer, and 2) the characterization of the viral specificit...

journal_title：Journal of medical virology

authors： Basson J,Tardy JC,Aymard M

更新日期：1991-03-01 00:00:00