Abstract:
:A healthy patient presented to Klinikum Altmühlfranken Weißenburg Hospital, Germany, with two morning attacks of painful muscle spasm in the left upper and lower limbs, without altered consciousness. Full examinations, radiological imaging, electroencephalography, lumbar puncture, and autoimmune profile were either normal or not consistent with patient's complaint. Subsequent epileptic episodes were observed on admission day and the following days; thus, the patient was diagnosed with focal epilepsy. The patient started to develop a fever and severe cough on day 4, and SARS-coronavirus-2 was confirmed through a nasopharyngeal swap. She received anticonvulsants and symptomatic treatments and completely recovered. This report emphasizes the potential nervous system involvement in severe acute respiratory syndrome-coronavirus-2 pathogenesis.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Elgamasy S,Kamel MG,Ghozy S,Khalil A,Morra ME,Islam SMSdoi
10.1002/jmv.26113subject
Has Abstractpub_date
2020-10-01 00:00:00pages
2238-2242issue
10eissn
0146-6615issn
1096-9071journal_volume
92pub_type
杂志文章abstract::Does anal HPV viral load explain the difference in anal HPV persistence between HIV-negative and -positive men who have sex with men (MSM)? MSM ≥18 years were recruited in Amsterdam, the Netherlands, in 2010-2011. Anal self-swabs were collected every 6 months and genotyped (SPF10 -PCR-DEIA-LIPA25 -system). HPV16 and H...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24898
更新日期:2018-01-01 00:00:00
abstract::The infectivity titer of a standard stock of the SAR-55 strain of hepatitis E virus (HEV) was determined in cynomolgus macaques (Macaca fascicularis) and the effect of dose on the course of the infection was examined by weekly monitoring of alanine aminotransferase (ALT) and anti-HEV levels. Antibody to HEV (anti-HEV)...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890430207
更新日期:1994-06-01 00:00:00
abstract::Many patients with coagulation disorders are infected with hepatitis C virus (HCV) that advances to end stage liver disease, resulting in an increased number of deaths. The efficacy of ribavirin and peginterferon combination therapy for chronic HCV infection in patients with coagulation disorders has not been clarifie...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23444
更新日期:2013-02-01 00:00:00
abstract::The importance of hepatitis B virus (HBV) genotypes for disease progression and response to interferon-alpha-based treatment is well established. While almost all patients in the Mediterranean area are infected with HBV genotype D, HBV genotype A is dominant in Northern Europe. However, the distribution of HBV genotyp...
journal_title:Journal of medical virology
pub_type: 杂志文章,多中心研究
doi:10.1002/jmv.21294
更新日期:2008-10-01 00:00:00
abstract::The effect of HHV-6 strain A infection on the expression of Epstein-Barr virus- (EBV-) encoded growth transformation-associated genes in two EBV-positive Burkitt lymphoma cell lines, Akata and P3HR-3, was investigated. The results indicate that HHV-6A upregulates the expression of the latent membrane protein LMP-1 in ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:1998-07-01 00:00:00
abstract::Acute hepatitis B virus (HBV) infection was diagnosed in 57 adults admitted to Toranomon Hospital in Tokyo, Japan. Genotypes of HBV were determined by a serological method and compared to those in 1,077 patients with chronic hepatitis B. The distribution of genotypes were: genotype A (acute, 22.8% vs. chronic, 1.9%; P...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.10239
更新日期:2002-12-01 00:00:00
abstract::The seroprevalence of viral hepatitis in healthcare workers has important public health implications. To assess the risk factors for the acquisition of viral hepatitis in an unvaccinated cohort from an hyperendemic region, 567 healthcare workers from a large hospital in the capital of the Republic of Yemen were interv...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20126
更新日期:2004-08-01 00:00:00
abstract::The criterion standard for the diagnosis of occult hepatitis C virus (HCV) infection is detection of HCV-RNA in liver cells. However, because of the invasive nature of liver biopsy, other methods have been studied. The present study aimed to identify subjects with occult HCV-4 infection among healthy sexual partners o...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24074
更新日期:2015-03-01 00:00:00
abstract::A sensitive and specific nonradioactive in situ hybridization method capable of detecting single-copy integrated hepatitis B virus (HBV) DNA sequences in hepatocellular carcinoma (HCC) cell lines was developed. In situ hybridization of biotinylated HBV (adr, adw) DNA probes with nine different human HCC cell lines wer...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890300407
更新日期:1990-04-01 00:00:00
abstract::Men who have sex with men (MSM) are an important risk group for human immunodeficiency virus (HIV) and at high-risk of herpesvirus infection. However, limited information on epidemiologic patterns of HHV8 and HSV2 among MSM is available in mainland China. A cross-sectional study of 486 participants was performed in Sh...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24718
更新日期:2017-05-01 00:00:00
abstract::Prophylactic antiviral therapy is recommended for hepatitis B virus (HBV)-infected patients with malignancies who are undergoing systemic chemotherapy. In the current study, we aimed to develop a risk scoring system to guide the selection of prophylactic antiviral agents. In this retrospective analysis, we included co...
journal_title:Journal of medical virology
pub_type: 杂志文章,多中心研究
doi:10.1002/jmv.25241
更新日期:2018-10-01 00:00:00
abstract::A reverse transcription-polymerase chain reaction (RT-PCR) was developed for the detection of Chikungunya virus infection. Based on the nonstructural protein 1 (nsP1) and glycoprotein E1 (E1) genes of Chikungunya, two primer sets were designed. Total RNA were extracted from the cell culture fluid of Aedes albopictus C...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.10085
更新日期:2002-07-01 00:00:00
abstract::It has been suggested that some individuals may present genetic susceptibility to SARS-CoV-2 infection, with particular research interest in variants of the ACE2 and TMPRSS2 genes, involved in viral penetration into cells, in different populations and geographic regions, although insufficient information is currently ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26319
更新日期:2021-02-01 00:00:00
abstract::A sensitive radioimmunoassay technique was used to detect hepatitis B e antigen (HBeAg). A strong correlation was found between HBeAg positivity of the serum of hepatitis B surface antigen (HBsAg) carrier women in Taiwan and the subsequent development of surface antigenemia in their babies. All babies who became chron...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890030310
更新日期:1979-01-01 00:00:00
abstract::Enteroviruses are responsible for hand, foot, and mouth disease, and have caused many deaths in China during recent years. But the natural history of enterovirus infection in children, especially asymptomatic children, is not yet clear. From April 2011 to May 2012, 505 stool and throat swab samples of children attendi...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23884
更新日期:2014-09-01 00:00:00
abstract::Fifty-three (96%) of 55 patients with coronary artery stenosis were positive for serum anti-HHV-6 IgG, and 50 (91%) of these patients had anti-HHV-7 IgG. The number of cases sero-positive for HHV-6 and -7 in the 54 age matched control volunteers was 52 (96%) and 53 (98%), respectively. No statistical difference in the...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.10134
更新日期:2002-08-01 00:00:00
abstract::The metastasis status of pelvic lymph nodes (PLNs) seems to be a predictive factor of survival. It was suggested that the presence of HPV DNA and other biological markers in PLN may indicate a sub clinical early metastasis. The aim was to describe the prevalence and distribution patterns of HPV DNA and H-ras mutations...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21076
更新日期:2008-04-01 00:00:00
abstract::Here, we studied the role of nitric oxide (NO) production during the first steps of the respiratory infection of BALB/c mice with herpes simplex virus type 1 (HSV-1), strain F. Nitric oxide synthase II (NOS-II) mRNA and protein were detected by reverse transcription (RT)-PCR and dot blot, respectively in samples of lu...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20093
更新日期:2004-06-01 00:00:00
abstract::Healthcare-associated infections with hepatitis C virus (HCV) hitherto have been observed mainly in hemodialysis settings as well as in hematology and oncology wards. In this communication, molecular and epidemiologic investigations to elucidate an HCV outbreak in an orthopedic ward are reported. One hundred and thirt...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21394
更新日期:2009-02-01 00:00:00
abstract::The presence of therapy-associated hepatitis B virus (HBV) variants is the main drawback of antiviral therapy for HBV infection. Moreover, drug-resistant variants are more insensitive to a second agent and more therapy-associated mutations will be present. To apply better nucleos(t)ide analogues (NA) and reduce the oc...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24006
更新日期:2015-09-01 00:00:00
abstract::The performance of French virology laboratories belonging to the ANRS network has been assessed annually for 3 years. The performance of these laboratories was compared between the years 2002 and 2003. Ten and 7 coded samples were sent to 38 virology laboratories in 2002 and 45 virology laboratories in 2003, respectiv...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20522
更新日期:2006-02-01 00:00:00
abstract::Hepatitis C virus core antigen (HCVcoreAg) may be measured in serum with a sensitive, recently validated assay. Beyond its value as a marker of viral infection, there are little data on its relation with clinical, histological, and virological parameters. In this study, the significance of HCVcoreAg levels was studied...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23672
更新日期:2013-11-01 00:00:00
abstract::It has been reported that low-plasma cytomegalovirus (CMV) DNA loads are associated with an increased risk of overall mortality in allogeneic hematopoietic stem cell transplantation (allo-HSCT). Utilizing a conservative strategy for initiation of preemptive antiviral therapy (>1500 IU/mL), we characterized the virolog...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.25426
更新日期:2019-06-01 00:00:00
abstract::From the Pacific Republic of Kiribati, 90/130 (69%) of hepatitis B-infected individuals carry antibodies to hepatitis delta virus. The prevalence of delta infection varied between geographically isolated subgroups in the population and delta antibodies were found more frequently in subjects over the age of 10. It is u...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890290210
更新日期:1989-10-01 00:00:00
abstract::In vitro, beta-herpesviruses can stimulate or inhibit HIV replication under particular circumstances. In order to investigate the effects of beta-herpesvirus infection on HIV replication and vice versa at an organ level, we determined the quantitative relationships between cytomegalovirus (CMV), human herpesviruses (H...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9071(199903)57:3<278::aid-jmv11
更新日期:1999-03-01 00:00:00
abstract::Stored demographic data and HIV RT and protease sequences of 877 HIV patients attending for the first time the HIV/AIDS outpatient clinics of a reference Infectious Diseases centre in Northern Italy between 1999 and 2006 were stratified by 3-year spanning periods according to date of HIV infection. In the period 1980-...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21163
更新日期:2008-06-01 00:00:00
abstract::Interferon alpha (IFN-alpha) therapy is currently the treatment of choice for chronic hepatitis C (HCV) infection, but it fails to achieve a sustained response in approximately 75% of those treated. The factors which determine whether or not an individual will respond to IFN-alpha are uncertain, although a number of p...
journal_title:Journal of medical virology
pub_type: 临床试验,杂志文章
doi:10.1002/jmv.1890450320
更新日期:1995-03-01 00:00:00
abstract::Most dengue virus (DENV) infections remain asymptomatic. This increases the risk of DENV transfusion transmission (TT-DENV) during outbreaks. We evaluated DENV viremia in 8475 blood donations assembled in minipools for the presence of DENV RNA. The tested samples were obtained between February and May, 2016, during a ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26619
更新日期:2020-10-22 00:00:00
abstract::SARS-CoV-2 infection is causing a pandemic disease that is reflected in challenging public health problems worldwide. Human leukocyte antigen (HLA)-based epitope prediction and its association with disease outcomes provide an important base for treatment design. A bioinformatic prediction of T cell epitopes and their ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26561
更新日期:2020-09-28 00:00:00
abstract::Serial serum samples from 20 untreated patients with chronic hepatitis C virus (HCV) infection were tested for HCV RNA by a nested polymerase chain reaction assay using primers from the highly conserved 5' noncoding region to determine the relationship between hepatitis C viremia and the activity of liver disease duri...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890410415
更新日期:1993-12-01 00:00:00