Characterization of immune complexes containing cytomegalovirus-specific IgM antibodies following a kidney graft.

abstract：:A seroprevalence study was carried out of six different human pathogenic viruses, namely human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), human T-cell leukemia virus (HTLV), human herpesvirus type 8 (HHV-8), and dengue virus among pregnant women and blood donors from rural (Nouna) ...

journal_title：Journal of medical virology

authors： Collenberg E,Ouedraogo T,Ganamé J,Fickenscher H,Kynast-Wolf G,Becher H,Kouyaté B,Kräusslich HG,Sangaré L,Tebit DM

更新日期：2006-05-01 00:00:00

abstract：:Sera from 31 human immunodeficiency virus (HIV)-infected patients, representing different clinical stages of HIV infection, were assayed for antibodies against measles and mumps viruses by various serological tests and compared to 23 healthy controls. Sera from four patients (two primary, one asymptomatic, and one acq...

journal_title：Journal of medical virology

authors： Kövamees J,Sheshberadaran H,Chiodi F,Schwartz S,Orvell C,Fenyö EM,Norrby E

更新日期：1988-09-01 00:00:00

abstract：:To investigate the intra-hepatic activation of the IFN system in patients affected by chronic HCV-infection in comparison with that observed in a non-infectious liver disease such as non-alcoholic steatohepatitis, we measured the liver steady state mRNA levels of interferon-alpha, interferon-beta and interferon-gamma ...

journal_title：Journal of medical virology

authors： Abbate I,Romano M,Longo R,Cappiello G,Lo Iacono O,Di Marco V,Paparella C,Spano A,Capobianchi MR

更新日期：2003-08-01 00:00:00

abstract：:A line of hepatitis C virus (HCV) transgenic mice was established previously that was mediated by Cre/loxP system using HCV cDNA, including core, E1, E2 and NS2 genes. Intravenous infection of a recombinant adenovirus that expresses Cre DNA recombinase (AxCANCre) induced HCV structural protein expression in the liver ...

journal_title：Journal of medical virology

authors： Wakita T,Katsume A,Kato J,Taya C,Yonekawa H,Kanegae Y,Saito I,Hayashi Y,Koike M,Miyamoto M,Hiasa Y,Kohara M

更新日期：2000-11-01 00:00:00

abstract：:The effects of 6-diazo-5-oxo-L-norleucine (DON), 2-deoxy-D-glucose (DOG), and tunicamycin (TM) on the replication of poliovirus (PV) and vesicular stomatitis virus (VSV) were examined. During a 48-hr replication period, TM, DON, and DOG inhibit VSV plaque formation in HEp-2 cells by 99.9%, 99.8%, and 99.9% respectivel...

journal_title：Journal of medical virology

authors： Goldstein G,Guskey LE

更新日期：1984-01-01 00:00:00

abstract：:A 6-month-old girl with active human cytomegalovirus (HCMV) infection developed Reye's syndrome after vaccination. She suffered from uncommon complications of HCMV infection, including Coombs-negative hemolytic anemia and cardiac injury, but recovered after the appropriate treatment with prompt ganciclovir and symptom...

journal_title：Journal of medical virology

authors： Qi Y,Liu X,Xu W,Ruan Q

更新日期：2013-03-01 00:00:00

abstract：:Although a T-cell response in human cytomegalovirus (HCMV)-immune individuals exists against the most abundantly expressed protein pp65 of the virus matrix, less is known about the determinants that evoke this response. The aim of the study was to identify regions within HCMV pp65 (ppUL83) that contain sequences for t...

journal_title：Journal of medical virology

authors： Khattab BA,Lindenmaier W,Frank R,Link H

更新日期：1997-05-01 00:00:00

abstract：:Norovirus is one of the major causes of outbreaks and sporadic cases of acute gastroenteritis in young children worldwide. Obtaining local baseline information regarding this virus is important for developing and evaluating prevention strategies of norovirus transmission in children. The age, seasonal distribution and...

journal_title：Journal of medical virology

authors： Xu J,Yang Y,Sun J,Ding Y

更新日期：2009-10-01 00:00:00

abstract：:HIV-1 drug resistance mutations (DRMs) and substitutions were assessed after the failure of the first line non-nucleoside reverse transcriptase inhibitors (NNRTIs) + 2 nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) treatment regimens (efavirenz [EFV] + lamivudine[3TC] + zidovudine [ZDV] vs. EFV + 3TC +...

journal_title：Journal of medical virology

authors： Avi R,Pauskar M,Karki T,Kallas E,Jõgeda EL,Margus T,Huik K,Lutsar I

更新日期：2016-03-01 00:00:00

abstract：:Human papillomaviruses (HPV) are the causative agents of most cervical carcinomas. A complete understanding of the HPV types that cause cervical carcinoma is needed as vaccines are designed. Fresh tissues are not always available for such studies. We therefore sought to determine the feasibility of HPV studies using f...

journal_title：Journal of medical virology

authors： Bryan JT,Taddeo F,Skulsky D,Jansen KU,Frain BM,Qadadri B,Brown DR

更新日期：2006-01-01 00:00:00

abstract：:The human papillomavirus (HPV) 16 genome has been studied extensively, although no study has focused on the E1 gene that is implicated in viral DNA replication. After analyzing the E1 region of HPV 16 genomes in 429 cervical samples, 11.2% were found to contain a 63 nucleotides duplication in this region. Sequence ana...

journal_title：Journal of medical virology

authors： Sabol I,Matovina M,Gasperov NM,Grce M

更新日期：2008-12-01 00:00:00

abstract：:Potential risk factors for the development of hepatocellular carcinoma were analysed in 40 Caucasian patients with this malignancy. A higher proportion (14 of 40; 35%) had evidence of hepatitis C virus (HCV) infection than had evidence of either hepatitis B virus (HBV) carriage (17.5%) or alcohol abuse (30%). In all 1...

journal_title：Journal of medical virology

authors： Garson JA,Wicki AN,Ring CJ,Joller H,Zala G,Schmid M,Buehler H

更新日期：1992-10-01 00:00:00

abstract：:The emergence of drug-resistant variants during antiretroviral therapy is a serious obstacle to sustained suppression of the human immunodeficiency virus type 1 (HIV-1). For that reason, resistance assays are essential to guide clinicians in the selection of optimal treatment regimens. Genotypic assays are less expens...

journal_title：Journal of medical virology

authors： Garcia-Perez J,Sanchez-Palomino S,Perez-Olmeda M,Fernandez B,Alcami J

更新日期：2007-02-01 00:00:00

abstract：:Interleukin 33 (IL-33) and soluble form of ST2 (sST2) are involved in inflammation. This study aimed to assess the role of serum IL-33 and sST2 in neonates with HCMV infection. The concentration of serum IL-33 and sST2 in 20 patients and 16 healthy controls were measure by enzyme-linked immune-sorbent assay (ELISA). T...

journal_title：Journal of medical virology

authors： Chen Y,Qian J

更新日期：2018-08-01 00:00:00

abstract：:Nineteen Chinese patients with chronic hepatitis B virus (HBV) infection, seropositive for HBV e antigen (HBeAg) and HBV DNA on at least three occasions in 6 months, were randomised to receive either recombinant human interferon-gamma (rIFN gamma) 0.1 mg/m2 intramuscularly thrice weekly for 16 weeks (n = 11) or no ant...

journal_title：Journal of medical virology

authors： Lau JY,Lai CL,Wu PC,Chung HT,Lok AS,Lin HJ

更新日期：1991-07-01 00:00:00

abstract：:False negativity in a commercial anti-HIV kit (IMx HIV-1/HIV-2 3rd Generation Plus (code 8B32) was investigated, and the kit that superseded it (IMx HIV-1/HIV-2 III Plus, code 8C98) was evaluated. In a comparison on 574 freshly collected anti-HIV-1-positive specimens, 97.2% were more reactive in 8C98 than in 8B32; 35....

journal_title：Journal of medical virology

authors： Parry JV,Perry KR,Harbour S,Burgess C,Mortimer PP,Blackburn NK,Martin D

更新日期：1998-10-01 00:00:00

abstract：:Recent epidemiological and immunohistochemical studies have indicated a possible link between measles virus and inflammatory bowel disease (IBD). The aim of this study was to use a sensitive and robust method for the detection of measles virus RNA in IBD and control clinical samples. Peripheral blood mononuclear cells...

journal_title：Journal of medical virology

authors： Chadwick N,Bruce IJ,Schepelmann S,Pounder RE,Wakefield AJ

更新日期：1998-08-01 00:00:00

abstract：:Human herpesvirus 6 (HHV-6) and human immunodeficiency virus type 1 (HIV-1) may interact during transplacental transmission of HIV-1. The placental syncytiotrophoblast layer serves as the first line of defense of the fetus against viruses. Patterns of replication of HHV-6 variant A (HHV-6A) and HIV-1 were analyzed in ...

journal_title：Journal of medical virology

authors： Csoma E,Bácsi A,Liu X,Szabó J,Ebbesen P,Beck Z,Kónya J,Andirkó I,Nagy E,Tóth FD

更新日期：2002-05-01 00:00:00

abstract：:Rotavirus A (RVA) is the leading cause of acute viral gastroenteritis in children under 5 years of age worldwide. G9P[8] is a common RVA genotype that has been persistently prevalent in Jiangsu, China. To determine the genetic diversity of G9P[8] RVAs, 7 representative G9P[8] strains collected from Suzhou Children's H...

journal_title：Journal of medical virology

authors： Xu C,Fu J,Ai J,Zhang J,Liu C,Huo X,Bao C,Zhu Y

更新日期：2018-09-01 00:00:00

abstract：:Attachment of hepatitis B virus to a hepatoblastoma cell line (HepG2) was examined using a synthetic peptide corresponding to the pre-S1 (21-47) region of the envelope protein. Scatchard analysis revealed a single class binding site of Kd 104 +/- 27 nM/l and 5.4 +/- 1.2 x 10(5) sites per cell. Competition of HBV with ...

journal_title：Journal of medical virology

authors： Dash S,Rao KV,Panda SK

更新日期：1992-06-01 00:00:00

abstract：:Chronic HCV infection has emerged as a complex multifaceted disease with manifestations extending beyond the liver. HCV plays a direct role in glucose metabolism leading to both insulin resistance and type 2 diabetes. To evaluate the changes in the glycemic state following Sofosbuvir-based treatment regimens in diabet...

journal_title：Journal of medical virology

authors： Abdel Alem S,Elsharkawy A,Fouad R,Adel E,Abdellatif Z,Musa S,Nagy A,Hussein MS,Yosry A,Esmat G

更新日期：2017-12-01 00:00:00

abstract：:Predictive factors of HCV relapse after treatment with DAAs are poorly understood. In this study, we aimed to assess whether the residual viral load positivity observed during or at the end of treatment (EOT) has an impact on viral outcome. Blood samples were collected from 337 patients with genotypes (GT) 1a, 1b, 2, ...

journal_title：Journal of medical virology

authors： Visco-Comandini U,Lapa D,Lionetti R,Taibi C,Loiacono L,Montalbano M,Capobianchi MR,D'Offizi G,Garbuglia AR

更新日期：2018-07-01 00:00:00

abstract：:Present diagnostic criteria for occult hepatitis B virus (HBV) infection requires blood or liver samples to test positive for at least two HBV DNA targets in hepatitis B surface antigen (HBsAg) negative individuals. These criteria were derived from studies involving referred or selected patient populations. The object...

journal_title：Journal of medical virology

authors： Minuk GY,Huynh C,Uhanova J,Osiowy C

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Patients with thalassemia may also have cardiac abnormalities due to congenital problems, anemia, and increased burden of iron in their myocardium. This study was designed to evaluate the effects of direct acting antiviral (DAA) therapy on the cardiac function of hepatitis C virus (HCV)-infected patients wit...

journal_title：Journal of medical virology

authors： Khosravi A,Karimi-Sari H,Abedi-Andani M,Behnava B,Namvar A,Anvar A,Alavian SM

更新日期：2019-03-01 00:00:00

abstract：:Human rhinovirus (HRV), a single-stranded, positive-sense RNA virus, is associated with mild upper respiratory tract infections in children. The aim of this study was to carry out a molecular characterization and phylogeny-based classification of the circulating genotypes of HRV in hospitalized children with clinical ...

journal_title：Journal of medical virology

authors： Espínola EE,Russomando G,Aquino C,Basualdo W

更新日期：2013-09-01 00:00:00

abstract：:Herpes simplex virus (HSV) DNA in the cerebrospinal fluid (CSF) of children with herpes simplex encephalitis (HSE) was quantified and typed using the polymerase chain reaction (PCR) assay. During the acute phase, HSV-DNA was detected in the CSF of 13 patients with HSE, including 5 neonates. A restriction profile of th...

journal_title：Journal of medical virology

authors： Ando Y,Kimura H,Miwata H,Kudo T,Shibata M,Morishima T

更新日期：1993-10-01 00:00:00

abstract：:A panel of deoxyoligonucleotide probes for studying the genetic variability and genotyping of Tick-borne encephalitis virus (TBEV) strains by molecular hybridization of nucleic acids (MHNA) was created. This panel allows to estimate the genetic structure of individual TBEV strains, as the targets for probes are both v...

journal_title：Journal of medical virology

authors： Demina TV,Dzhioev YP,Verkhozina MM,Kozlova IV,Tkachev SE,Plyusnin A,Doroshchenko EK,Lisak OV,Zlobin VI

更新日期：2010-05-01 00:00:00

abstract：:Crimean-Congo hemorrhagic fever infection (CCHF) is a viral zoonosis. The pathogenesis of this disease has not been established so far, however, cytokines account for its progression and outcome. The aim of the present study is to investigate the association between chemokine receptor 5 (CCR5) gene Δ32 mutation and pa...

journal_title：Journal of medical virology

authors： Rustemoglu A,Ekinci D,Nursal AF,Barut S,Duygu F,Günal Ö

更新日期：2017-10-01 00:00:00

abstract：:Nucleotide sequences of the hypervariable region (HVR) of the E2/NS1 gene of hepatitis C virus (HCV), which are now thought to contain epitopes for neutralizing antibodies, were compared between antibody-bound HCV and free HCV in a patient with type II cryoglobulinemia. Antibody-bound HCV was immunoprecipitated with a...

journal_title：Journal of medical virology

authors： Kurosaki M,Enomoto N,Nouchi T,Sakuma I,Marumo F,Sato C

更新日期：1995-08-01 00:00:00

abstract：:The prevalence of picobirnaviruses (PBVs) in human stools was investigated by polyacrylamide gel electrophoresis (PAGE) analysis of 832 faecal specimens collected between 1982 and 1993 from patients in various clinical groups. Similar prevalences (9-13%) were detected in patients with or without gastroenteritis and th...

journal_title：Journal of medical virology

authors： Gallimore CI,Appleton H,Lewis D,Green J,Brown DW

更新日期：1995-02-01 00:00:00