Comparison of the efficacy of sofosbuvir plus ribavirin in Chinese patients with genotype 3a or 3b HCV infection.

abstract：:Travel influences the spread of non-B subtypes of HIV in Europe. The aim of this study was to assess whether the spread of non-B subtypes occurred in Croatia, a country with a low level HIV infection. Phylogenetic analysis of the reverse transcriptase and protease genes was undertaken in 145 Croatian patients with the...

journal_title：Journal of medical virology

authors： Ramirez-Piedad MK,Lepej SZ,Yerly S,Begovac J

更新日期：2009-04-01 00:00:00

abstract：:Many countries are studying currently the possibility of mass vaccination against varicella. The objective of this study was to provide a complete picture of the pre-vaccine epidemiology of the Varicella-Zoster Virus in England and Wales to aid in the design of immunisation programs. Population-based data including ge...

journal_title：Journal of medical virology

authors： Brisson M,Edmunds WJ

更新日期：2003-01-01 00:00:00

abstract：:Nineteen Chinese patients with chronic hepatitis B virus (HBV) infection, seropositive for HBV e antigen (HBeAg) and HBV DNA on at least three occasions in 6 months, were randomised to receive either recombinant human interferon-gamma (rIFN gamma) 0.1 mg/m2 intramuscularly thrice weekly for 16 weeks (n = 11) or no ant...

journal_title：Journal of medical virology

authors： Lau JY,Lai CL,Wu PC,Chung HT,Lok AS,Lin HJ

更新日期：1991-07-01 00:00:00

abstract：:It has been reported that low-plasma cytomegalovirus (CMV) DNA loads are associated with an increased risk of overall mortality in allogeneic hematopoietic stem cell transplantation (allo-HSCT). Utilizing a conservative strategy for initiation of preemptive antiviral therapy (>1500 IU/mL), we characterized the virolog...

journal_title：Journal of medical virology

authors： Talaya A,Giménez E,Piñana JL,Albert E,Hernández-Boluda JC,Pérez A,Torres I,Solano C,Navarro D

更新日期：2019-06-01 00:00:00

abstract：:Human metapneumovirus (hMPV) is considered an important cause of acute respiratory infections. hMPV can cause morbidity in hematopoietic stem cell transplant recipients and recent research has demonstrated that it is an important virus in patients admitted to hospital with respiratory infections and suspected of havin...

journal_title：Journal of medical virology

authors： Souza JS,Watanabe A,Carraro E,Granato C,Bellei N

更新日期：2013-03-01 00:00:00

abstract：:From the Pacific Republic of Kiribati, 90/130 (69%) of hepatitis B-infected individuals carry antibodies to hepatitis delta virus. The prevalence of delta infection varied between geographically isolated subgroups in the population and delta antibodies were found more frequently in subjects over the age of 10. It is u...

journal_title：Journal of medical virology

authors： Tibbs CJ

更新日期：1989-10-01 00:00:00

abstract：:COVID-19 pandemic has affected over 100 countries in a matter of weeks. People's response toward social distancing in the emerging pandemic is uncertain. In this study, we evaluated the influence of information (formal and informal) sources on situational awareness of the public for adopting health-protective behavior...

journal_title：Journal of medical virology

authors： Qazi A,Qazi J,Naseer K,Zeeshan M,Hardaker G,Maitama JZ,Haruna K

更新日期：2020-07-01 00:00:00

abstract：:Here, we studied the role of nitric oxide (NO) production during the first steps of the respiratory infection of BALB/c mice with herpes simplex virus type 1 (HSV-1), strain F. Nitric oxide synthase II (NOS-II) mRNA and protein were detected by reverse transcription (RT)-PCR and dot blot, respectively in samples of lu...

journal_title：Journal of medical virology

authors： Gamba G,Cavalieri H,Courreges MC,Massouh EJ,Benencia F

更新日期：2004-06-01 00:00:00

abstract：:Twenty marmosets, male Callithrix jacchus, were used during this study. Fifteen of the marmosets were inoculated with 5,000 TCID50 of the attenuated XJC13 strain of Junin virus by intramuscular route and five were left as uninoculated controls. Animals were observed for a 420-day period. In order to carry out virologi...

journal_title：Journal of medical virology

authors： Avila MM,Frigerio MJ,Weber EL,Rondinone S,Samoilovich SR,Laguens RP,de Guerrero LB,Weissenbacher MC

更新日期：1985-01-01 00:00:00

abstract：:Enterovirus 71 H (E71 H), an isolate from an adult patient with hand-food-mouth disease (HFMD) in China, was serologically similar to the prototype strain E71 BrCr, which was isolated from a patient with aseptic meningitis. The study further analyzed the similarity of E71 H to E71 BrCr at the 5'-noncoding region (NCR)...

journal_title：Journal of medical virology

authors： Zheng ZM,He PJ,Caueffield D,Neumann M,Specter S,Baker CC,Bankowski MJ

更新日期：1995-10-01 00:00:00

abstract：:The infectivity titer of a standard stock of the SAR-55 strain of hepatitis E virus (HEV) was determined in cynomolgus macaques (Macaca fascicularis) and the effect of dose on the course of the infection was examined by weekly monitoring of alanine aminotransferase (ALT) and anti-HEV levels. Antibody to HEV (anti-HEV)...

journal_title：Journal of medical virology

authors： Tsarev SA,Tsareva TS,Emerson SU,Yarbough PO,Legters LJ,Moskal T,Purcell RH

更新日期：1994-06-01 00:00:00

abstract：:A hepatitis B vaccination campaign was carried out in a town of 60,000 inhabitants, Afragola, Campania, Italy, a hyperendemic area for hepatitis B where HBsAg prevalence was 13.4% and anti-HBc prevalence was 64.7%. This experimental pilot project aimed to reduce the incidence of both acute and asymptomatic viral hepat...

journal_title：Journal of medical virology

authors： Da Villa G,Piazza M,Iorio R,Picciotto L,Peluso P,De Luca G,Basile B

更新日期：1992-04-01 00:00:00

abstract：:Influenza A(H1N1)pdm09 virus pandemic struck India in 2009 and continues to cause outbreaks in its post-pandemic phase. Diminutive information is available about influenza A(H1N1)pdm09 from central India. This observational study presents epidemiological and molecular findings for the period of 6 years. Throat swab sa...

journal_title：Journal of medical virology

authors： Sahu M,Singh N,Shukla MK,Potdar VA,Sharma RK,Sahare LK,Ukey MJ,Barde PV

更新日期：2018-03-01 00:00:00

abstract：:The complete VP1 protein of EV71 was truncated into six segments and fused to the C-terminal ends of full-length nucleocapsid protein (NPfl) and truncated NP (NPt; lacks 20% amino acid residues from its C-terminal end) of newcastle disease virus (NDV). Western blot analysis using anti-VP1 rabbit serum showed that the ...

journal_title：Journal of medical virology

authors： Sivasamugham LA,Cardosa MJ,Tan WS,Yusoff K

更新日期：2006-08-01 00:00:00

abstract：:Adenovirus infections are usually mild or even asymptomatic, but infections with the virus are being recognized increasingly as a major cause of mortality and morbidity in the immunocompromised, particularly hematological stem cell transplant patients where infections can be life threatening and mortality may reach 60...

journal_title：Journal of medical virology

authors： Al Qurashi YM,Guiver M,Cooper RJ

更新日期：2011-11-01 00:00:00

abstract：:A thirteen-year-old boy with bilateral orchitis was diagnosed as being infected by Coxsackie A9 virus by isolation of the virus from a throat swab and a fecal specimen. Serologic investigations revealed the development of transitory specific neutralizing IgM antibodies against the isotate and of persistent antibodies ...

journal_title：Journal of medical virology

authors： Willems WR,Hornig C,Bauer H,Klingmüller V

更新日期：1978-01-01 00:00:00

abstract：:Polyomavirus infection occurring during childhood is followed by a lifelong latency in immunocompetent subjects. The major site of polyomavirus persistence are the uroepithelial cells which leads to oral transmission. It has recently been hypothesized that tonsils could be a possible reservoir. The role of tonsil, ade...

journal_title：Journal of medical virology

authors： Comar M,Zanotta N,Bovenzi M,Campello C

更新日期：2010-07-01 00:00:00

abstract：:In 2000, we monitored the course and persistence of human papillomavirus (HPV) infection in 54 women who were HPV positive and free of any cytological disease using HPV-DNA genotyping with a linear array assay (baseline). The impact of HPV infection on development of cervical cytological abnormality (dyskaryosis) was ...

journal_title：Journal of medical virology

authors： Cuschieri KS,Whitley MJ,Cubie HA

更新日期：2004-05-01 00:00:00

abstract：:The long-term efficacy of lamivudine therapy in patients with hepatitis B virus (HBV) infection is still not clear. In this study, 20 non-cirrhotic Japanese patients infected with HBV received lamivudine therapy for more than 1 year and were followed for a median period of 8.5 years (range, 6.7-8.7 years). The rates o...

journal_title：Journal of medical virology

authors： Akuta N,Suzuki F,Suzuki Y,Sezaki H,Hosaka T,Someya T,Kobayashi M,Saitoh S,Arase Y,Ikeda K,Kobayashi M,Kumada H

更新日期：2005-04-01 00:00:00

abstract：:Seasonal fluctuations in hepatitis A have been observed in the Netherlands related to Turkish and Moroccan children after visiting their home countries. This study determined the prevalence and associated factors of hepatitis A virus (HAV) antibodies in Turkish and Moroccan children in Rotterdam. A random sample was t...

journal_title：Journal of medical virology

authors： Richardus JH,Vos D,Veldhuijzen IK,Groen J

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Seasonal influenza is an annual occurrence that leads to large community outbreaks and increased hospitalisation. A number of studies have suggested that influenza A (FLUAV) is associated with increased rates of hospitalisation and mortality compared to influenza B (FLUBV). This study compared demographic an...

journal_title：Journal of medical virology

authors： Mabayoje DA,Cutino-Moguel T,Haigh J,Wilks M,Welch CA,Melzer M

更新日期：2020-10-15 00:00:00

abstract：:The seroprevalence of antibodies to hepatitis E virus (HEV) and hepatitis A virus (HAV) was determined in a community-based sample in innercity London where socioeconomic conditions were expected to result in a high prevalence of antibodies to HAV, and in which the presence of immigrants from the developing world pose...

journal_title：Journal of medical virology

authors： Bernal W,Smith HM,Williams R

更新日期：1996-07-01 00:00:00

abstract：:Varicella in the immunocompetent adult is an infrequent but potentially serious infection. Previous studies in immunocompetent hosts and normal adults have demonstrated the value of intravenous acyclovir in the treatment of varicella-zoster virus infections. Oral acyclovir has also shown efficacy in both normal adults...

journal_title：Journal of medical virology

authors： Wallace MR,Bowler WA,Oldfield EC 3rd

更新日期：1993-01-01 00:00:00

abstract：:The prevalence of delta agent among 120 Chinese patients with HBsAg-positive chronic active and hepatocellular carcinoma from Taiwan and Los Angeles were studied by serological assay for antibody to delta antigen and immunoperoxidase staining for delta antigen in the liver biopsies. Of 120 patients, only four with chr...

journal_title：Journal of medical virology

authors： Govindarajan S,Lee SD,Tong MJ,Tsai YT,Lo KJ

更新日期：1984-01-01 00:00:00

abstract：:Isolates of hepatitis A virus (HAV) are of a single serotype, with human isolates being categorised within four genotypes. In addition, there are three genotypes exclusively associated with Old World monkeys. In some geographical regions, related isolates cluster suggesting endemic spread of the virus, while in other ...

journal_title：Journal of medical virology

authors： Taylor MB

更新日期：1997-04-01 00:00:00

abstract：:Human T-lymphotropic virus type 1 (HTLV-1) infection causes adult T-cell leukemia and is characterized by long periods of clinical latency with low levels of viral production. Transcription of HTLV-1 is controlled through sequences in the promoter and enhancer regions of the long terminal repeat of the integrated prov...

journal_title：Journal of medical virology

authors： Newbound GC,O'Rourke JP,Collins ND,Andrews JM,DeWille J,Lairmore MD

更新日期：2000-10-01 00:00:00

abstract：:Herpesviruses produce assembly proteins (AP) that act as scaffolding proteins for the assembly of the viral capsids. The products of the assemblin gene, which encodes both maturational protease and AP, have been established for herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (CMV). We cloned an inframe O...

journal_title：Journal of medical virology

authors： Garcia-Valcarcel M,Fowler WJ,Harper DR,Jeffries DJ,Layton GT

更新日期：1997-12-01 00:00:00

abstract：:Hepatitis E is endemic in India. It was recently noted that although all the Indian human hepatitis E virus (HEV) isolates (1976-2001) were placed in genotype I, the swine HEV recovered from western India (2000) belonged to genotype IV. This was in contrast to reports from the United States and Taiwan wherein both hum...

journal_title：Journal of medical virology

authors： Arankalle VA,Chobe LP,Walimbe AM,Yergolkar PN,Jacob GP

更新日期：2003-03-01 00:00:00

abstract：:Paired sera, saliva and cervicovaginal secretions from 17 HTLV-I-infected women (19-75 yr) were tested for total IgA and IgG, for IgA and IgG to the immunodominant region gp46/175-Pro-199, for serum IgG to the neutralizing domains gp46/ 190-Pro-199 and gp46/190-Ser-199, or for tax-rex proviral HTLV-DNA. Serum antibodi...

journal_title：Journal of medical virology

authors： Bélec L,Georges-Courbot MC,Georges A,Mohamed AS,Londos-Gagliardi D,Hallouin MC,Hocini H,Guillemain B

更新日期：1996-09-01 00:00:00

abstract：:Exacerbations of chronic hepatitis B have been associated with accumulation of mutations in the HBV core gene, with amino acid (aa) substitutions clustering between aa 50 and 69. This region of the nucleocapsid protein is known as an immunodominant epitope for CD4+ T-lymphocytes, however the impact of these mutations ...

journal_title：Journal of medical virology

authors： Torre F,Cramp M,Owsianka A,Dornan E,Marsden H,Carman W,Williams R,Naoumov NV

更新日期：2004-03-01 00:00:00