Influenza A virus in Taiwan, 1980-2006: Phylogenetic and antigenic characteristics of the hemagglutinin gene.

Abstract:

:Limited amount of information is available in Taiwan on the genetic or antigenic characteristics of influenza A virus prior to the establishment of a Taiwan surveillance network in 2000. Isolates of H1N1 and H3N2 viruses in Taiwan between 1980 and 2006 were studied, and part of the hemagglutinin gene was analyzed due to its importance in terms of viral infection and antibody neutralization. Results from a phylogenetic analysis indicate continuous evolutionary topology in H3N2 isolates, and two distinct H1N1 lineages. Many genetic relationships between vaccine strains and epidemic isolates appearing in Taiwan before other global locations were also observed and recorded in addition to a gradual increase in the number of N-linked glycosylation sites on partial HA1 proteins since 1980. The results from pairwise comparisons of HA1 nucleotide and deduced amino acid sequences indicate shared identities within groups organized according to their bootstrap and P-values of approximately 95.5-100% and 95.7-100% in H1N1 and 94.5-100% and 93.2-100% in H3N2 viruses, respectively. Comparisons of amino acid substitutions in the five antigenic regions reveal highly non-synonymous changes occurring in the Sb region of H1N1 and in the B region of H3N2. The results of an antigenic analysis using a hemagglutinin inhibition (HI) test indicate the presence of some epidemic strains 1-2 years earlier in Taiwan than in other parts of the world, as well as higher vaccine mismatch rates. This information supports the need for continuous surveillance of emerging influenza viruses in Taiwan, which will be useful for making global vaccine decisions.

journal_name

J Med Virol

authors

Wang SF,Lee YM,Chan YJ,Liu HF,Yen YF,Liu WT,Huang JC,Chen YM

doi

10.1002/jmv.21531

subject

Has Abstract

pub_date

2009-08-01 00:00:00

pages

1457-70

issue

8

eissn

0146-6615

issn

1096-9071

journal_volume

81

pub_type

杂志文章
  • Effect of rotavirus vaccine implementation on the prevalence of coinfections with enteric viruses in Norway.

    abstract::Acute gastroenteritis (AGE) is a common illness in both adults and children worldwide and is caused by several microorganisms including viruses, bacteria, and parasites. Rotavirus (RV), which is the main cause of AGE, can occur as a mixed infection with other viruses. The aim of this study is to assess the molecular e...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26013

    authors: Gibory M,Dembinski JL,Flem E,Haltbakk I,Dudman SG

    更新日期:2020-05-15 00:00:00

  • HIV-1 Thai B strain has spread out of former plasma donors into general population through sexual contact in Henan, China.

    abstract::Henan, China is characterized by the outbreak of HIV epidemic of Thai B strain in former plasma donors in 1990s. After the forbidden of paid blood donation, whether Thai B strain will spread out of former plasma donors into sexual transmitted population is unknown. To answer the question, phylogenetic analysis was use...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24383

    authors: Li L,Sun G,Zhong P,Han J,Li T,Jia D,Liu Y,Sun C,Wang Z,Li H,Wang X,Li J

    更新日期:2016-04-01 00:00:00

  • Redetection of HBV lamivudine-resistant mutations in a patient under entecavir therapy, who had been treated sequentially with nucleos(t)ide analogues.

    abstract::Development of hepatitis B virus (HBV)-resistant strains following nucleos(t)ide analog treatment is a major medical concern. This report describes a case of an adult patient with chronic HBV infection, sequentially treated with the nucleos(t)ide analogues, lamivudine, adefovir, and entecavir. During monotherapy with ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20982

    authors: Rodriguez-Frias F,Jardi R,Schaper M,Gimferrer M,Elefsiniotis I,Tabernero D,Esteban R,Buti M

    更新日期:2007-11-01 00:00:00

  • Relative frequency of human rotavirus subgroups 1 and 2 in Japanese children with acute gastroenteritis.

    abstract::Recently developed monoclonal antibodies against the 42,000-dalton major inner capsid protein were used in an enzyme immunoassay to subgroup a total of 156 rotavirus specimens obtained from Japanese infants and young children with acute gastroenteritis during the period between December 1981 and April 1983. Only 2 spe...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890170105

    authors: Nakagomi O,Nakagomi T,Oyamada H,Suto T

    更新日期:1985-09-01 00:00:00

  • Risk and clearance of GB virus C/hepatitis G virus infection in homosexual men: A longitudinal study.

    abstract::The risk and clearance of GB virus type C (GBV-C)/hepatitis G virus (HGV) infection was investigated in a cohort of homosexual men (n=180; median follow-up time, 7 years). The interaction between GBV-C/HGV RNA and antibodies against the E2 region of the virus, and the clinical impact of chronic GBV-C/HGV infection wer...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9071(199911)59:3<303::aid-jmv7>

    authors: Stark K,Doering CD,Bienzle U,Pauli G,Hamouda O,Engel AM,Schreier E

    更新日期:1999-11-01 00:00:00

  • Assessment of in vitro prophylactic and therapeutic efficacy of chloroquine against Chikungunya virus in vero cells.

    abstract::The resurgence of Chikungunya virus (CHIKV) in the form of unprecedented and explosive epidemics in India and the Indian Ocean islands after a gap of 32 years is a major public health concern. Currently, there is no specific therapy available to treat CHIKV infection. In the present study, the in vitro prophylactic an...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21663

    authors: Khan M,Santhosh SR,Tiwari M,Lakshmana Rao PV,Parida M

    更新日期:2010-05-01 00:00:00

  • Impact of disease-modifying drugs on the severity of  COVID-19 infection in multiple sclerosis patients.

    abstract::Recent evidence suggested that neurological manifestations occur in patients with a severe form of coronavirus disease (COVID-19). On the basis of this issue, neurologists are very concerned about patients with neurological disorders, especially multiple sclerosis (MS), as consumers of immunosuppressive or immune-modu...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/jmv.26593

    authors: Rostami Mansoor S,Ghasemi-Kasman M

    更新日期:2020-10-12 00:00:00

  • Efficacy of lamivudine in HBeAg-negative chronic hepatitis B.

    abstract::Hepatitis B e antigen (HBeAg)-negative chronic hepatitis B results from infection with hepatitis B virus mutants unable to produce HBeAg. It accounts for 7-30% of patients with chronic hepatitis B virus (HBV) worldwide, with the highest rates reported for Mediterranean Europe and Asia. Interferon (IFN) is currently th...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,评审

    doi:

    authors: Rizzetto M

    更新日期:2002-04-01 00:00:00

  • Evidence for persistence of parvovirus B19 DNA in livers of adults.

    abstract::Recent studies have suggested a pathogenic role of human parvovirus B19 (B19) in the development of acute fulminant liver failure in children. The hypothesis was based on the detection of B19 DNA in 8 of 10 explanted livers of children requiring liver transplantation. In the present study, explanted livers from 43 adu...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.2047

    authors: Eis-Hübinger AM,Reber U,Abdul-Nour T,Glatzel U,Lauschke H,Pütz U

    更新日期:2001-10-01 00:00:00

  • Development of strategies for screening, predicting, and diagnosing intrauterine HBV infection in infants born to HBsAg positive mothers.

    abstract::This study aimed at developing strategies for screening, predicting, and diagnosing intrauterine HBV infection in infants born to HBsAg positive mothers. A total of 1,360 infants born to 1,355 HBsAg positive mothers were followed for 1 year. All newborn infants received active and passive immunization within 24 hr aft...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23667

    authors: Yin YZ,Zhang J,Wu LL,Zhou J,Zhang PZ,Zhou SS

    更新日期:2013-10-01 00:00:00

  • Molecular analysis of HPV 16 E6I/E6II spliced mRNAs and correlation with the viral physical state and the grade of the cervical lesion.

    abstract::The presence of HPV 16 E6*I/E6*II spliced transcripts, in cervical lesions of different grade, was analyzed to characterize the transcription pattern. The presence and amount of spliced transcripts were correlated with DNA viral markers such as E2/E6 ratio and physical state. The detection of HPV 16 E6*I/E6*II mRNAs w...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21496

    authors: Cricca M,Venturoli S,Leo E,Costa S,Musiani M,Zerbini M

    更新日期:2009-07-01 00:00:00

  • Emergence of G3 and G9 rotavirus and increased incidence of mixed infections in the southern region of Ireland 2001-2004.

    abstract::Two hundred and thirty fecal specimens were collected from children (up to 5 years of age) admitted with suspected rotaviral gastroenteritis at four Irish hospitals (Cork University Hospital, Mercy Hospital, Cork, Waterford Regional Hospital, and Kerry General Hospital) in the southern region of Ireland, between 2001 ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20494

    authors: Reidy N,O'Halloran F,Fanning S,Cryan B,O'Shea H

    更新日期:2005-12-01 00:00:00

  • Ozone as adjuvant support in the treatment of COVID-19: A preliminary report of probiozovid trial.

    abstract::The evaluation of new therapeutic resources against coronavirus disease 2019 (COVID-19) represents a priority in clinical research considering the minimal options currently available. To evaluate the adjuvant use of systemic oxygen-ozone administration in the early control of disease progression in patients with COVID...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26636

    authors: Araimo F,Imperiale C,Tordiglione P,Ceccarelli G,Borrazzo C,Alessandri F,Santinelli L,Innocenti GP,Pinacchio C,Mauro V,Recchia GE,Zancla S,Calò A,Poscia R,Ruberto F,d'Ettorre G,Bilotta F,Mastroianni C,Pugliese F

    更新日期:2020-10-28 00:00:00

  • Prevalence of sexually transmitted pathogens associated with HPV infection in cervical samples in a Mexican population.

    abstract::Cervical cancer development has been mainly associated with persistent human papillomavirus (HPV) infections. However, HPV infection is unlikely to be sufficient to cause cervical cancer, and the contribution of other sexually transmitted infections (STIs) could be the determining factor for cervical lesion-progressio...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24278

    authors: Magaña-Contreras M,Contreras-Paredes A,Chavez-Blanco A,Lizano M,De la Cruz-Hernandez Y,De la Cruz-Hernandez E

    更新日期:2015-12-01 00:00:00

  • Laboratory diagnosis and surveillance of human respiratory viruses by PCR in Victoria, Australia, 2002-2003.

    abstract::Respiratory viruses were identified by the polymerase chain reaction (PCR) in more than 4,200 specimens collected during 2002 and 2003 in Victoria, Australia from patients admitted to hospitals or participating in an influenza surveillance program. Influenza viruses and picornaviruses were important causes of morbidit...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20246

    authors: Druce J,Tran T,Kelly H,Kaye M,Chibo D,Kostecki R,Amiri A,Catton M,Birch C

    更新日期:2005-01-01 00:00:00

  • Isolation and serial propagation of human group C rotaviruses in a cell line (CaCo-2).

    abstract::Rotaviruses were detected via electron microscopy in fecal specimens collected from school children during an outbreak of diarrhea and from a sporadic case in 1993 in Japan. All of the viruses were found to belong to human group C rotavirus by reverse passive hemagglutination assay (RPHA). These viruses replicated wel...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9071(199601)48:1<48::AID-JMV8>3

    authors: Shinozaki K,Yamanaka T,Tokieda M,Shirasawa H,Simizu B

    更新日期:1996-01-01 00:00:00

  • Identification of the novel KI Polyomavirus in paranasal and lung tissues.

    abstract::KI is a novel polyomavirus identified in the respiratory secretions of children with acute respiratory symptoms. Whether this reflects a causal role of the virus in the human respiratory disease remains to be established. To investigate the presence of KIV in the respiratory tissue, we examined 20 fresh lung cancer sp...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21417

    authors: Babakir-Mina M,Ciccozzi M,Campitelli L,Aquaro S,Lo Coco A,Perno CF,Ciotti M

    更新日期:2009-03-01 00:00:00

  • Coxsackievirus B1 reveals strain specific differences in plasmacytoid dendritic cell mediated immunogenicity.

    abstract::Enterovirus infections are usually mild but can also cause severe illnesses and play a role in chronic diseases, such as cardiomyopathies and type 1 diabetes. Host response to the invading virus can markedly modulate the course of the infection, and this response varies between individuals due to the polymorphism of i...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23903

    authors: Hämäläinen S,Nurminen N,Ahlfors H,Oikarinen S,Sioofy-Khojine AB,Frisk G,Oberste MS,Lahesmaa R,Pesu M,Hyöty H

    更新日期:2014-08-01 00:00:00

  • Comparative studies of the immunogenic activity of hepatitis B surface antigen (HBsAg) and HBsAg polypeptides.

    abstract::Three hepatitis B surface antigen (HBsAg) preparations were compared: purified intact 22-nm HBsAg particles; HBsAg-derived, sodium dodecyl sulfate (SDS)-denatured P25 + GP30 polypeptide pool; and nondenatured P25 + GP30 micelles. The micelles had the same polypeptide composition as the P25 + GP30 pool. The immunogenic...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890110205

    authors: Sanchez Y,Ionescu-Matiu I,Melnick JL,Dreesman GR

    更新日期:1983-01-01 00:00:00

  • Low-level plasma HIVs in patients on prolonged suppressive highly active antiretroviral therapy are produced mostly by cells other than CD4 T-cells.

    abstract::The cellular source(s) and the clinical significance of persistent low-level viremia, below 50 HIV RNA copies per ml of plasma, achieved in many patients with high adherence to highly active antiretroviral therapy (HAART) remain unclear. Also, it is not clear if residual plasma HIVs during HAART can become predominant...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21366

    authors: Sahu GK,Paar D,Frost SD,Smith MM,Weaver S,Cloyd MW

    更新日期:2009-01-01 00:00:00

  • Detection of measles virus RNA in whole blood stored on filter paper.

    abstract::The purpose of this study was to evaluate the use of dried blood spots stored on filter paper as a means to provide specimens for virologic surveillance for measles virus (MV) in situations when the reverse cold chain is not available. Two single-step RT-PCR assays were evaluated for sensitivity of detection of MV nuc...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.10144

    authors: Katz RS,Premenko-Lanier M,McChesney MB,Rota PA,Bellini WJ

    更新日期:2002-08-01 00:00:00

  • Nucleotide sequence of hepatitis B virus isolated from subjects without serum anti-hepatitis B core antibody.

    abstract::The nucleotide sequences of the precore/core and X open reading frames (ORFs) of hepatitis B virus (HBV) were studied in four subjects who were serologically negative for anti-hepatitis B core antibody. These subjects were positive for serum hepatitis B surface antigen and were considered to be asymptomatic HBV carrie...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890460306

    authors: Gotoh K,Mima S,Uchida T,Shikata T,Yoshizawa K,Irie M,Mizui M

    更新日期:1995-07-01 00:00:00

  • Analysis of hepatitis C virus strains circulating in Republic of the Congo.

    abstract::The aim of this study was to assess the seroprevalence, viremia, genotype distribution, and demographic history of hepatitis C virus (HCV) in the Republic of the Congo. Testing was carried out on sera samples collected in 2005 from 807 Bantus belonging to the Kongo, Teke, and Ngala subgroups and 80 Pygmies. Positive H...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21724

    authors: Cantaloube JF,Gallian P,Bokilo A,Jordier F,Biagini P,Attoui H,Chiaroni J,de Micco P

    更新日期:2010-04-01 00:00:00

  • Molecular epidemiology of astroviruses in Japan from 1995 to 1998 by reverse transcription-polymerase chain reaction with serotype-specific primers (1 to 8).

    abstract::In addition to the serotype-specific primers described previously (1 to 7), a new serotype 8-specific primer has been designed, allowing detection of all astrovirus serotypes. A total of 1,382 diarrheal stool samples in 5 regions in Japan were examined by reverse transcription-polymerase chain reaction (RT-PCR). The i...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Sakamoto T,Negishi H,Wang QH,Akihara S,Kim B,Nishimura S,Kaneshi K,Nakaya S,Ueda Y,Sugita K,Motohiro T,Nishimura T,Ushijima H

    更新日期:2000-07-01 00:00:00

  • Treatment with cytotoxic immunosuppression agents increases urinary excretion of JCV in patients with autoimmune disease.

    abstract::Human JC virus is ubiquitous in human populations and is reactivated frequently in immunosuppressed patients. Fifty-one patients with autoimmune disease receiving immunomodulating therapy were evaluated to study the possible relationship between immunosuppression and JCV viruria. Patients were divided into cytotoxic a...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/1096-9071(200012)62:4<505::aid-jmv16>3.0.c

    authors: Wang M,Tsai RT,Ou WC,Lin CK,Tsay GJ,Chang H,Chang D

    更新日期:2000-12-01 00:00:00

  • Transmission of hepatitis A virus among recently captured Panamanian owl monkeys.

    abstract::The presence of antibody to hepatitis A virus (anti-HAV) in 60% of procured owl monkeys (Aotus trivirgatus) held within the United States prompted a study of recently captured A trivirgatus in Panama. Only 2 of 145 newly captured monkeys, but all of 35 A trivirgatus held within a colony for over 100 days, were found t...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890100105

    authors: Lemon SM,LeDuc JW,Binn LN,Escajadillo A,Ishak KG

    更新日期:1982-01-01 00:00:00

  • Replication of enhancer-deficient amphotropic murine leukemia virus in human fibrosarcoma but not in primary human fibroblasts.

    abstract::Amphotropic murine leukemia virus (MLV) replicates in cells from various mammalian species including humans and is a potential contaminant in MLV vector preparations for human gene transfer studies. In general, MLV replication depends on the expression of viral genes under the control of 75 bp enhancer elements in the...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.10202

    authors: Reuss FU,Berdel B,Heber R,Bantel-Schaal U

    更新日期:2002-10-01 00:00:00

  • Detection of herpesvirus-6A in a case of subacute cerebellitis and myoclonic dystonia.

    abstract::This is a case study of a child who developed roseola infantum first, then varicella, and was later affected by acute cerebellar syndrome, severe truncal ataxia, and myoclonic dystonia. Human herpesvirus 6 (HHV-6) A and B were detected in the cerebrospinal fluid (CSF) and peripheral blood, respectively, upon ataxia on...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20285

    authors: Borghi E,Pagani E,Mancuso R,Delbue S,Valli M,Mazziotti R,Giordano L,Micheli R,Ferrante P

    更新日期:2005-03-01 00:00:00

  • Tula and Puumala hantavirus NSs ORFs are functional and the products inhibit activation of the interferon-beta promoter.

    abstract::The S RNA genome segment of hantaviruses carried by Arvicolinae and Sigmodontinae rodents encodes the nucleocapsid (N) protein and has an overlapping (+1) open reading frame (ORF) for a putative nonstructural protein (NSs). The aim of this study was to determine whether the ORF is functional. A protein corresponding t...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20948

    authors: Jääskeläinen KM,Kaukinen P,Minskaya ES,Plyusnina A,Vapalahti O,Elliott RM,Weber F,Vaheri A,Plyusnin A

    更新日期:2007-10-01 00:00:00

  • Sequence-specific detection method for reverse transcription, loop-mediated isothermal amplification of HIV-1.

    abstract::HIV diagnosis at the point-of-care or in resource-limited settings poses considerable challenges due to time and cost limitations. Currently, nucleic acid-based tests are the only reliable method for diagnosing recent infections during the window period post-infection and pre-seroconversion, but these tests are only s...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21490

    authors: Curtis KA,Rudolph DL,Owen SM

    更新日期:2009-06-01 00:00:00