Detection of herpesvirus-6A in a case of subacute cerebellitis and myoclonic dystonia.

Abstract:

:This is a case study of a child who developed roseola infantum first, then varicella, and was later affected by acute cerebellar syndrome, severe truncal ataxia, and myoclonic dystonia. Human herpesvirus 6 (HHV-6) A and B were detected in the cerebrospinal fluid (CSF) and peripheral blood, respectively, upon ataxia onset. The intricacy of this case suggests multifaceted conclusions ranging from the need for a multidirectional approach to neurological diseases, to confirmation of a more pronounced neurotropism of HHV-6A and a possible role of viruses in myoclonic dystonia syndrome, although this last hypothesis should be confirmed by larger studies.

journal_name

J Med Virol

authors

Borghi E,Pagani E,Mancuso R,Delbue S,Valli M,Mazziotti R,Giordano L,Micheli R,Ferrante P

doi

10.1002/jmv.20285

keywords:

subject

Has Abstract

pub_date

2005-03-01 00:00:00

pages

427-9

issue

3

eissn

0146-6615

issn

1096-9071

journal_volume

75

pub_type

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