Characterization of a nucleic acid probe for the diagnosis of human coronavirus 229E infections.

abstract：:Intramuscular (IM) influenza vaccines are about 50% effective in preventing clinical illness among the elderly and their effectiveness in eliciting mucosal response may be even lower. The aim of the present study was to evaluate the immunological effect of a novel inactivated intranasal (IN) trivalent whole influenza ...

journal_title：Journal of medical virology

authors： Muszkat M,Yehuda AB,Schein MH,Friedlander Y,Naveh P,Greenbaum E,Schlesinger M,Levy R,Zakay-Rones Z,Friedman G

更新日期：2000-05-01 00:00:00

abstract：:Knowledge of the precise timing of SARS-CoV-2 infection may be of clinical and epidemiological relevance. The presence of low-avidity IgGs has conventionally been considered an indicator of recent infection. Here, we carried out qualitative assessment of SARS-CoV-2-specific antibody avidity using an urea (6M) dissocia...

journal_title：Journal of medical virology

authors： Valdivia A,Torres I,Huntley D,Alcaraz MJ,Albert E,Colomina J,Ferrer J,Carratalá A,Navarro D

更新日期：2021-02-01 00:00:00

abstract：:The prevalence of HCV genotypes in four republics of the former Soviet Union (Russia, Belarus, Moldova, and Uzbekistan) was investigated. Overall, 197 HCV isolates from 66 blood donors and 131 patients with chronic hepatitis were typed. Viral sequences from sera of infected subjects were amplified by nested RT-PCR usi...

journal_title：Journal of medical virology

authors： Viazov S,Kuzin S,Paladi N,Tchernovetsky M,Isaeva E,Mazhul L,Vasychova F,Widell A,Roggendorf M

更新日期：1997-09-01 00:00:00

abstract：:Interleukin 6 (IL-6) is a pleiotropic cytokine with pivotal functions in the regulation of the biological responses of several target cells, including hepatocytes. Previous studies have shown that serum IL-6 levels are increased in hepatitis B patients. However, the role of IL-6 in modulating the anti-hepatitis B viru...

journal_title：Journal of medical virology

authors： Yang K,Guan S,Zhang H,Chen Z

更新日期：2019-05-01 00:00:00

abstract：:A total of 190 specimens from South Indian children aged 0-59 months with ocular anomalies consistent with suspected congenital rubella syndrome (CRS) were investigated. Twenty-six of the 65 infants (40%) were confirmed as CRS by detection of rubella specific IgM. Rubella RNA was detected in 41 samples from 26 infants...

journal_title：Journal of medical virology

authors： Rajasundari TA,Sundaresan P,Vijayalakshmi P,Brown DW,Jin L

更新日期：2008-03-01 00:00:00

abstract：:Hepatitis C Virus (HCV) NS3 protease is an attractive target for antiviral agent development because it is required for viral replication. Because a stable cell culture system or small animal model to study HCV replication is not readily available, we constructed an in vitro model allowing the investigation of NS3 tra...

journal_title：Journal of medical virology

authors： Heintges T,Encke J,zu Putlitz J,Wands JR

更新日期：2001-12-01 00:00:00

abstract：:Paired serum and saliva samples were tested by enzyme-linked immunosorbent assay (ELISA) and Western blot (WB) for the presence of human immunodeficiency virus (HIV) antibodies. The study group included 36 individuals known to be HIV seropositive and 14 healthy, seronegative controls. HIV antibodies were detected in a...

journal_title：Journal of medical virology

authors： Holmström P,Syrjänen S,Laine P,Valle SL,Suni J

更新日期：1990-04-01 00:00:00

abstract：:The aim of the study was to assess whether high-risk pregnant women have a higher prevalence of HEV during the perinatal period. This was a cross-sectional study of 428 patients: Group 1, 127 women with a high-risk pregnancy; Group 2, 97 asymptomatic people with reactivity to HCV or HBV; Group 3, 94 patients with clin...

journal_title：Journal of medical virology

authors： Baptista-González H,Trueba-Gómez R,Rosenfeld-Mann F,Roque-Álvarez E,Méndez-Sánchez N

更新日期：2017-11-01 00:00:00

abstract：:The genotypic inhibitory quotient (GIQ) is the ratio between drug concentration and the number of resistance mutations. However, as different resistance scores can be calculated for the same protease inhibitor, the ability of a GIQ to predict the virological outcome may vary depending on the resistance score used as t...

journal_title：Journal of medical virology

authors： Gianotti N,Galli L,Danise A,Hasson H,Boeri E,Lazzarin A,Castagna A

更新日期：2006-12-01 00:00:00

abstract：:G1P[8] rotaviruses are predominant in causing diarrheal infections in humans all over the world. This study reports the analysis of complete genomes of G1P[8] strains, two each recovered from Rotarix™ vaccine recipients and non-recipients hospitalized for acute gastroenteritis in Pune, western India. All four strains ...

journal_title：Journal of medical virology

authors： Pradhan GN,Chitambar SD

更新日期：2018-04-01 00:00:00

abstract：:The avalanche of genomic data generated from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus requires the development of tools to detect and monitor its mutations across the world. Here, we present a webtool, coronapp, dedicated to easily processing user-provided SARS-CoV-2 genomic sequences and...

journal_title：Journal of medical virology

authors： Mercatelli D,Triboli L,Fornasari E,Ray F,Giorgi FM

更新日期：2020-11-18 00:00:00

abstract：:The TD97 strain vaccine virus was prepared from the Tanabe strain measles virus by low-temperature passages in primary cell cultures and ultraviolet (UV) mutagenesis. The TD97 strain exhibited the following characteristics: highly temperature sensitive, neither multiplying nor forming any plaques at 40 degrees C in Ve...

journal_title：Journal of medical virology

authors： Suzuki K,Morita M,Katoh M,Kidokoro M,Saika S,Yoshizawa S,Hashizume S,Horiuchi K,Okabe N,Shinozaki T

更新日期：1990-11-01 00:00:00

abstract：:Studies have described clinical features of patients with coronavirus disease (COVID-19). However, limited data concerning the clinical characteristics of the Italian deaths are available. We aim to describe the clinical and epidemiological characteristics of 320 deceased from the Italian experience. We retrospectivel...

journal_title：Journal of medical virology

authors： Biagi A,Rossi L,Malagoli A,Zanni A,Sticozzi C,Comastri G,Gandolfi S,Villani GQ

更新日期：2020-11-01 00:00:00

abstract：:It remains unclear if China's current HIV antibody testing algorithm misses a substantial number of HIV infected individuals. Of 196 specimens with indeterminate or negative results on HIV western blot (WB) retrospectively examined by HIV-1 nucleic acid test (NAT), 67.57% (75/111) of indeterminate WB samples, and 16.4...

journal_title：Journal of medical virology

authors： Liu MQ,Zhu ZR,Kong WH,Tang L,Peng JS,Wang X,Xu J,Schilling RF,Cai T,Zhou W

更新日期：2016-08-01 00:00:00

abstract：:In order to elucidate the pathogenesis of variant B human herpesvirus 6 (HHV-6) infection in skin tissues, an A431 cell line was inoculated with variant B HHV-6. HHV-6 causes abortive infection in the A431 cells, because neither late antigen (OHV-3 antigen) nor progeny virus is produced. Maximum levels of HHV-6 antige...

journal_title：Journal of medical virology

authors： Yoshikawa T,Goshima F,Akimoto S,Ozaki T,Iwasaki T,Kurata T,Asano Y,Nishiyama Y

更新日期：2003-09-01 00:00:00

abstract：:Recently, several clusters of hepatitis A have been observed among hemophiliacs linked to factor VIII concentrates treated for virus inactivation solely with the solvent/detergent (S/D) method, a procedure that does not affect nonenveloped viruses such as the hepatitis A virus (HAV). A new outbreak of hepatitis A in s...

journal_title：Journal of medical virology

authors： Chudy M,Budek I,Keller-Stanislawski B,McCaustland KA,Neidhold S,Robertson BH,Nübling CM,Seitz R,Löwer J

更新日期：1999-02-01 00:00:00

abstract：:In this meta-analysis, we evaluated the diagnostic role of Epstein-Barr virus deoxyribonucleic acid detection and quantitation in the serum of pediatric and young adult patients with infectious mononucleosis. The primary outcome of this meta-analysis was the sensitivity and specificity of Epstein-Barr virus (EBV) deox...

journal_title：Journal of medical virology

authors： Jiang SY,Yang JW,Shao JB,Liao XL,Lu ZH,Jiang H

更新日期：2016-05-01 00:00:00

abstract：:Although many reports have already shown RSV outbreaks among hemato-oncology patients, genomic studies detecting similar RSV strains prior to an outbreak in the hospital are rare. In 2014, the University of the Ryukyus hospital hemato-oncology unit experienced, and successfully managed, a respiratory syncytial virus (...

journal_title：Journal of medical virology

authors： Nabeya D,Kinjo T,Parrott GL,Uehara A,Motooka D,Nakamura S,Nahar S,Nakachi S,Nakamatsu M,Maeshiro S,Haranaga S,Tateyama M,Tomoyose T,Masuzaki H,Horii T,Fujita J

更新日期：2017-08-01 00:00:00

abstract：:The presence of hepatitis GB virus C (GBV-C), also known as hepatitis G virus (HGV), and hepatitis C virus (HCV) were investigated in sera from 45 hemophiliacs from nine locations in Nicaragua using a nested polymerase chain reaction (PCR). Primers used to detect GBV-C and HCV derived from the helicase region and 5'UT...

journal_title：Journal of medical virology

authors： González-Pérez MA,Norder H,Bergström A,Lopéz E,Visoná KA,Magnius LO

更新日期：1997-06-01 00:00:00

abstract：:Recently, it was demonstrated that the Varicella-zoster virus (VZV) infection led to an activation of MAP kinases. The viral protein encoded by ORF61 is a major effector of JNK/SAPK and p38/MAPK phosphorylation. ORF61 shows homology to HSV-1 ICP0, a multifunctional protein that influences the activity of c-Jun in infe...

journal_title：Journal of medical virology

authors： Rahaus M,Desloges N,Wolff MH

更新日期：2005-07-01 00:00:00

abstract：:We have attempted to reactivate human herpesvirus 6 (HHV-6) by infection with HHV-7 using childhood exanthem subitum patients in vitro. Peripheral blood mononuclear cells (PBMCs) were collected from children who had a history of exanthem subitum(ES) by HHV-6 and were infected by human herpesvirus 7 (HHV-7) in vitro. T...

journal_title：Journal of medical virology

authors： Tanaka-Taya K,Kondo T,Nakagawa N,Inagi R,Miyoshi H,Sunagawa T,Okada S,Yamanishi K

更新日期：2000-03-01 00:00:00

abstract：:Guinea pigs infected with Argentine hemorrhagic fever virus (Junin) were treated with pooled, homologous convalescent sera. Use of 15,000 or 5,000 therapeutic units of immune sera prevented all signs of illness when administered within 24 hr of infection. We could also prevent illness and death in infected guinea pigs...

journal_title：Journal of medical virology

authors： Kenyon RH,Green DE,Eddy GA,Peters CJ

更新日期：1986-11-01 00:00:00

abstract：:A line of hepatitis C virus (HCV) transgenic mice was established previously that was mediated by Cre/loxP system using HCV cDNA, including core, E1, E2 and NS2 genes. Intravenous infection of a recombinant adenovirus that expresses Cre DNA recombinase (AxCANCre) induced HCV structural protein expression in the liver ...

journal_title：Journal of medical virology

authors： Wakita T,Katsume A,Kato J,Taya C,Yonekawa H,Kanegae Y,Saito I,Hayashi Y,Koike M,Miyamoto M,Hiasa Y,Kohara M

更新日期：2000-11-01 00:00:00

abstract：:Herpes simplex virus (HSV) establishes latency in neurons and recurrent infections in oral mucosa. This prospective study analyzes HSV prevalence in oral mucosal brush samples from men with known human papillomavirus (HPV) status. We hypothesized that HSV-1-infection could facilitate HPV persistence as a cofactor. Thi...

journal_title：Journal of medical virology

authors： Mäki J,Paavilainen H,Kero K,Hukkanen V,Syrjänen S

更新日期：2018-03-01 00:00:00

abstract：:Flow cytometric analysis of CD4(+) and CD8(+) T cells specific to human cytomegalovirus (CMV) was undertaken in seven patients with congenital CMV infection, six healthy infants who had acquired infection, and six CMV-seropositive adults. Intracellular cytokine assays showed that 0.03-2.23% of CD4(+) T cells in the he...

journal_title：Journal of medical virology

authors： Hayashi N,Kimura H,Morishima T,Tanaka N,Tsurumi T,Kuzushima K

更新日期：2003-10-01 00:00:00

abstract：:To recognize the period of exaggerated cytokine response in patients with coronavirus disease 2019 (COVID-19) pneumonia, and to describe the clinical outcomes of using tocilizumab as a treatment option. The data of 12 adult COVID-19 pneumonia patients who were followed in the inpatient clinics of Biruni University Med...

journal_title：Journal of medical virology

authors： Borku Uysal B,Ikitimur H,Yavuzer S,Ikitimur B,Uysal H,Islamoglu MS,Ozcan E,Aktepe E,Yavuzer H,Cengiz M

更新日期：2020-11-01 00:00:00

abstract：:During the 1976 Ebola virus outbreak in Sudan, the investigations team gained the impression that fewer haemorrhagic manifestations and few fatalities occurred during the later stages of the epidemic after the virus had undergone several generations in man. This impression was also noted in guinea pigs experimentally ...

journal_title：Journal of medical virology

authors： Bowen ET,Platt GS,Lloyd G,Raymond RT,Simpson DI

更新日期：1980-01-01 00:00:00

abstract：:Asymptomatic carriers have a major influence on the spreading of norovirus infections. The objective of this study was to examine the characteristics of patients and asymptomatic carriers affected by norovirus-related community gastroenteritis outbreaks. No significant difference between the two groups was observed in...

journal_title：Journal of medical virology

authors： Mori K,Konishi N,Suzuki Y,Harada S,Maeda M,Akase S,Obata H,Monma C,Nagano M,Kimoto K,Oda M,Somura Y,Hirai A,Shinkai T,Noda M,Sadamasu K

更新日期：2018-12-01 00:00:00

abstract：:In countries with a low prevalence of human T-lymphotropic virus (HTLV) infection, indeterminate HTLV serologies are a major problem in blood bank screening because of the uncertainties about infection in these cases. The recent discovery of two new types of simian T-lymphotropic viruses (STLV), which give an HTLV-ind...

journal_title：Journal of medical virology

authors： Vandamme AM,Van Laethem K,Liu HF,Van Brussel M,Delaporte E,de Castro Costa CM,Fleischer C,Taylor G,Bertazzoni U,Desmyter J,Goubau P

更新日期：1997-05-01 00:00:00

abstract：:The criterion standard for the diagnosis of occult hepatitis C virus (HCV) infection is detection of HCV-RNA in liver cells. However, because of the invasive nature of liver biopsy, other methods have been studied. The present study aimed to identify subjects with occult HCV-4 infection among healthy sexual partners o...

journal_title：Journal of medical virology

authors： El Shazly Y,Hemida K,Rafik M,Al Swaff R,Ali-Eldin ZA,GadAllah S

更新日期：2015-03-01 00:00:00