Expression of hepatitis B surface and core antigens and transforming growth factor-alpha in "oval cells" of the liver in patients with hepatocellular carcinoma.

abstract：:The objectives of this study were to evaluate the reliability of herpes simplex virus (HSV) PCR testing in cerebrospinal fluid (CSF) for the detection of herpes simplex encephalitis. This was done by examining retrospectively the clinical follow-up of a large group of patients tested routinely by HSV-PCR. In addition,...

journal_title：Journal of medical virology

authors： Puchhammer-Stöckl E,Presterl E,Croÿ C,Aberle S,Popow-Kraupp T,Kundi M,Hofmann H,Wenninger U,Gödl I

更新日期：2001-08-01 00:00:00

abstract：:Despite a significant decrease in acute hepatitis A in the last 2 decades in Italy, outbreaks were observed occurring mostly in southern Italy. In this study, Bayesian phylogenetic analysis was used to analyze the origin of these epidemics. With this aim, 5 different data sets of hepatitis A virus sequences were built...

journal_title：Journal of medical virology

authors： Cella E,Riva E,Angeletti S,Fogolari M,Blasi A,Scolamacchia V,Spoto S,Bazzardi R,Lai A,Sagnelli C,Sagnelli E,Ciccozzi M

更新日期：2018-09-01 00:00:00

abstract：:GB Virus C (GBV-C) is a non-pathogenic flavivirus, commonly found in HIV infected patients. Studies suggest a survival benefit of GBV-C viremia in HIV infection. Impact of GBV-C viremia was evaluated on clinical outcome in multidrug-resistant HIV. The OPTIMA study enrolled advanced multidrug-resistant HIV patients wit...

journal_title：Journal of medical virology

authors： Sahni H,Kirkwood K,Kyriakides TC,Stapleton J,Brown ST,Holodniy M,OPTIMA Study Team.

更新日期：2014-03-01 00:00:00

abstract：:A sensitive and specific nonradioactive in situ hybridization method capable of detecting single-copy integrated hepatitis B virus (HBV) DNA sequences in hepatocellular carcinoma (HCC) cell lines was developed. In situ hybridization of biotinylated HBV (adr, adw) DNA probes with nine different human HCC cell lines wer...

journal_title：Journal of medical virology

authors： Tay N,Chan SH,Ren EC

更新日期：1990-04-01 00:00:00

abstract：:It has been generally believed that the Epstein-Barr virus (EBV)-encoded small RNA 1 and 2 (EBER1 and EBER2) genes are conserved as two families that correlated with type 1 (B95-8) and type 2 (AG876 or P3HR-1) EBV strains. EBER polymorphism and its association with EBV-associated disease have not received much attenti...

journal_title：Journal of medical virology

authors： Wang Y,Zhang X,Chao Y,Jia Y,Xing X,Luo B

更新日期：2010-05-01 00:00:00

abstract：:Sex differences in the predictors for hepatocellular carcinoma (HCC) development after direct-acting antiviral (DAA) therapy was investigated. DAA therapy was given to 1438 (663 male, 775 female) patients. Sex differences in the HCC development rate and the factors contributing to HCC development after DAA therapy wer...

journal_title：Journal of medical virology

authors： Watanabe T,Tokumoto Y,Joko K,Michitaka K,Horiike N,Tanaka Y,Tada F,Kisaka Y,Nakanishi S,Yamauchi K,Yukimoto A,Nakamura Y,Hirooka M,Abe M,Hiasa Y

更新日期：2020-05-06 00:00:00

abstract：:Ultra violet (UV) light-inactivated measles virus was used for the lymphocyte proliferation assay, where it caused consistently adult human peripheral blood monolymphocytes (PBML) proliferation which was not dependent on the measles virus complement fixation titre in the donor's sera. When the cord blood lymphocytes f...

journal_title：Journal of medical virology

authors： Tu R

更新日期：1995-06-01 00:00:00

abstract：OBJECTIVE:The unprecedented demand for testing for the ongoing coronavirus disease-2019 (COVID-19) pandemic caused by SARS-CoV-2 has led to an acute shortage and limited availability of test reagents for which pooling of samples has been recommended in areas with low prevalence. Considering the possibility of dilution ...

journal_title：Journal of medical virology

authors： Mohanty S,Ravindra A,Gupta K,Hallur V,Behera B,Mahaptra A,Saha S,Ranjan J,Payal P,Mohanty M,Rath S,Mishra B

更新日期：2020-10-21 00:00:00

abstract：:An enzyme-linked immunosorbent assay (ELISA) test using polyvalent antigens and antisera was used to detect Coxsackie B virus-specific IgM responses in 329 patients admitted to the Coronary Care Unit, Wellington Hospital, New Zealand over a 12-month period. The sera of 30 of 153 (19.6%) patients with acute myocardial ...

journal_title：Journal of medical virology

authors： Lau RC

更新日期：1986-02-01 00:00:00

abstract：:Hepatitis E virus (HEV) is a feco-orally transmitted pathogen and one of the most common cause of acute hepatitis worldwide. Recent studies in developed countries suggested that a direct human-to-human contact such as for sexually transmitted diseases may play a significant role in the HEV spread. The aim of this stud...

journal_title：Journal of medical virology

authors： Greco L,Uceda Renteria SC,Guarneri D,Orlandi A,Zoccoli A,Benardon S,Cusini M,Lunghi G

更新日期：2018-08-01 00:00:00

abstract：:The aetiological agents responsible for, and the outcome of, acute liver failure were investigated prospectively in 44 children (29 males, 15 females) attending a tertiary health care facility in India. The children were between the ages of 2 months and 13 years. Studies for viral infections and other etiologies could...

journal_title：Journal of medical virology

authors： Arora NK,Nanda SK,Gulati S,Ansari IH,Chawla MK,Gupta SD,Panda SK

更新日期：1996-03-01 00:00:00

abstract：:The recent emergence of coronavirus disease 2019 (COVID-19) pandemic has reassessed the usefulness of historic convalescent plasma transfusion (CPT). This review was conducted to evaluate the effectiveness of CPT therapy in COVID-19 patients based on the publications reported till date. To our knowledge, this is the f...

journal_title：Journal of medical virology

authors： Rajendran K,Krishnasamy N,Rangarajan J,Rathinam J,Natarajan M,Ramachandran A

更新日期：2020-09-01 00:00:00

abstract：:Little information about immunity to respiratory syncytial virus (RSV) and disease pathogenesis in elderly persons exists. Humoral immunity to RSV was assessed in 41 young, 56 healthy elderly, and 49 frail elderly adults by measuring baseline RSV specific IgG by enzyme immunoassay (EIA) and microneutralization assay (...

journal_title：Journal of medical virology

authors： Falsey AR,Walsh EE,Looney RJ,Kolassa JE,Formica MA,Criddle MC,Hall WJ

更新日期：1999-10-01 00:00:00

abstract：:The incidence and the outcome of cytomegalovirus (CMV) infections were evaluated in 83 adult recipients of allogenic bone marrow transplantation. Virological and serological surveillance was performed weekly for 3 months posttransplant, and then every other week or every month until 1 year. CMV infection occurred in 4...

journal_title：Journal of medical virology

authors： Guyotat D,Gibert R,Chomel J,Archimbaud E,Bossard S,Maupas J,Fiere D,Aymard M

更新日期：1987-12-01 00:00:00

abstract：:Our studies of rotavirus challenge in adult volunteers enabled us to evaluate the relationship of pre-existing antirotavirus fecal IgA antibody to infection and illness and to investigate the local response to this infection. No relationship could be found between the pre-existing levels of fecal antirotavirus IgA ant...

journal_title：Journal of medical virology

authors： Bernstein DI,Ziegler JM,Ward RL

更新日期：1986-12-01 00:00:00

abstract：:To evaluate the variation over time of seroreactivity to human papillomavirus type 11 (HPV-11) according to disease outcome, we selected a sample of 42 condyloma acuminatum patients from a group of subjects enrolled in a placebo-controlled trial of three alpha-interferon preparations administered parenterally for the ...

journal_title：Journal of medical virology

authors： Bonnez W,Da Rin C,Rose RC,Tyring SK,Reichman RC

更新日期：1993-04-01 00:00:00

abstract：:The substitution of amino acid (aa) 70 of arginine for glutamine and/or that of aa91 of leucine for methionine in the core protein in patients infected with hepatitis C virus (HCV) genotype 1b is associated with a poor response to pegylated interferon and ribavirin. Factors influencing these substitutions were sought ...

journal_title：Journal of medical virology

authors： Kobayashi M,Akuta N,Suzuki F,Hosaka T,Sezaki H,Kobayashi M,Suzuki Y,Arase Y,Ikeda K,Watahiki S,Mineta R,Iwasaki S,Miyakawa Y,Kumada H

更新日期：2010-01-01 00:00:00

abstract：:Human rhinovirus (HRV), a single-stranded, positive-sense RNA virus, is associated with mild upper respiratory tract infections in children. The aim of this study was to carry out a molecular characterization and phylogeny-based classification of the circulating genotypes of HRV in hospitalized children with clinical ...

journal_title：Journal of medical virology

authors： Espínola EE,Russomando G,Aquino C,Basualdo W

更新日期：2013-09-01 00:00:00

abstract：:Enteroviruses (EVs) are RNA viruses that can cause many clinical syndromes including acute flaccid paralysis (AFP). Within the global polio laboratory network, EVs are categorized either as polioviruses or non-polio enteroviruses (NPEVs). Specific NPEVs have been described in polio-like residual paralytic events in AF...

journal_title：Journal of medical virology

authors： Tushabe P,Howard W,Bwogi J,Birungi M,Eliku JP,Kakooza P,Bukenya H,Namuwulya P,Gaizi J,Tibanagwa M,Kabaliisa T,Mulindwa J,Muhanguzi D,Suchard M,Gumede N,Bakamutumaho B

更新日期：2021-01-17 00:00:00

abstract：:Attachment of hepatitis B virus to a hepatoblastoma cell line (HepG2) was examined using a synthetic peptide corresponding to the pre-S1 (21-47) region of the envelope protein. Scatchard analysis revealed a single class binding site of Kd 104 +/- 27 nM/l and 5.4 +/- 1.2 x 10(5) sites per cell. Competition of HBV with ...

journal_title：Journal of medical virology

authors： Dash S,Rao KV,Panda SK

更新日期：1992-06-01 00:00:00

abstract：:Glycoproteins of enveloped viruses replicating in nonprimate mammalian cells carry α-1,3-galactose (α-Gal) glycans, and can bind to anti-Gal antibodies which are abundant in humans. The antibodies have protected humans and their ancestors for millions of years, because they inhibit replication of many kinds of microbe...

journal_title：Journal of medical virology

authors： Chen JM

更新日期：2020-07-18 00:00:00

abstract：:HCV strains belonging to genotype 4 may be gaining endemicity across Continental Europe but the extent of their spread in the United Kingdom is unknown. Sera referred from patients attending hospitals in England between 2004 through 2008 were characterised. A total of 243 sera carried HCV genotype 4. The most common s...

journal_title：Journal of medical virology

authors： Ngui SL,Brant L,Markov PV,Tung JP,Pybus OG,Teo CG,Ramsay ME

更新日期：2015-03-01 00:00:00

abstract：:Persistent infection with high-risk human papillomavirus (HPV) causes cervical preneoplasic lesions and invasive cervical cancer. This study evaluated the prevalence and distribution of HPV genotypes in cervical exfoliated cells from Uruguayan women. Five hundred sixty-eight cervical specimens were examined by PCR usi...

journal_title：Journal of medical virology

authors： Ramas V,Mirazo S,Bonilla S,Mendoza L,Lago O,Basiletti J,González J,Picconi MA,Arbiza J

更新日期：2013-05-01 00:00:00

abstract：:SARS-CoV-2 infection is causing a pandemic disease that is reflected in challenging public health problems worldwide. Human leukocyte antigen (HLA)-based epitope prediction and its association with disease outcomes provide an important base for treatment design. A bioinformatic prediction of T cell epitopes and their ...

journal_title：Journal of medical virology

authors： Romero-López JP,Carnalla-Cortés M,Pacheco-Olvera DL,Ocampo-Godínez JM,Oliva-Ramírez J,Moreno-Manjón J,Bernal-Alferes B,López-Olmedo N,García-Latorre E,Domínguez-López ML,Reyes-Sandoval A,Jiménez-Zamudio L

更新日期：2020-09-28 00:00:00

abstract：:Studies of hepatitis B virus (HBV) infection in non-human primates such as chimpanzees are no longer possible due to ethical considerations and the endangered status of chimpanzees since April 2007 in Japan. A human hepatocyte transplanted chimeric mouse was used to characterize HBV infectivity in serial stages of acu...

journal_title：Journal of medical virology

authors： Tabuchi A,Tanaka J,Katayama K,Mizui M,Matsukura H,Yugi H,Shimada T,Miyakawa Y,Yoshizawa H

更新日期：2008-12-01 00:00:00

abstract：:In early 2008, a sudden increase in oseltamivir (Tamiflu)-resistant influenza A H1N1 viruses was reported from several European countries. This resistant virus has spread globally and accounted for more than 95% of H1N1 viruses isolated in the following influenza season. A continuous close monitoring on the prevalence...

journal_title：Journal of medical virology

authors： Ngai KL,Lam WY,Lee N,Leung TF,Hui DS,Chan PK

更新日期：2010-08-01 00:00:00

abstract：:To compare characteristics and outcomes of patients who had COVID-19 with Mycoplasma pneumoniae immunoglobulin M (IgM) antibodies to those without M. pneumoniae antibodies. We retrospectively reviewed cases admitted over a 4-week period between 17 March 2020 and 14 April 2020 to the Hoboken University Medical Center, ...

journal_title：Journal of medical virology

authors： Amin D,McKitish K,Shah PS

更新日期：2021-02-01 00:00:00

abstract：:In total 1,525 blood serum samples were collected in October, 2013 in Russian Asia from people who reside in territories that are at high risk for emergence of influenza viruses with pandemic potential. Presence of antibodies to influenza viruses in the sera was tested in hemagglutination inhibition test. None of the ...

journal_title：Journal of medical virology

authors： Ilyicheva T,Abdurashitov M,Durymanov A,Susloparov I,Goncharova N,Kolosova N,Mikheev V,Ryzhikov A

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND AIM:Genotype 3b hepatitis C virus (HCV) infection represents approximately 50% of patients with genotype 3 in China. We compared the efficacy of sofosbuvir (SOF) plus ribavirin (RBV) in Chinese patients with genotype 3a and 3b HCV. METHODS:The analyzed data are from a phase 3, open-label study of SOF pl...

journal_title：Journal of medical virology

authors： Huang R,Rao H,Xie Q,Gao Z,Li W,Jiang D,Mo H,Massetto B,Stamm LM,Brainard DM,Wei L

更新日期：2019-07-01 00:00:00

abstract：:Neutralization of virus is likely to be necessary for development of an effective prophylactic vaccine against genital human papillomavirus (HPV) infection. Two New Zealand white rabbits were immunized with purified HPV type 11 (HPV 11) virions in Freund's adjuvant. An enzyme linked immunoassay (ELISA) was used to det...

journal_title：Journal of medical virology

authors： Bryan JT,Jansen KU,Lowe RS,Fife KH,McClowry T,Glass D,Brown DR

更新日期：1997-11-01 00:00:00