Rotavirus fecal IgA antibody response in adults challenged with human rotavirus.

abstract：:Interleukin 6 (IL-6) is a pleiotropic cytokine with pivotal functions in the regulation of the biological responses of several target cells, including hepatocytes. Previous studies have shown that serum IL-6 levels are increased in hepatitis B patients. However, the role of IL-6 in modulating the anti-hepatitis B viru...

journal_title：Journal of medical virology

authors： Yang K,Guan S,Zhang H,Chen Z

更新日期：2019-05-01 00:00:00

abstract：:Major differences exist between HIV-1 and HIV-2 in terms of epidemiology, pathogenicity, sensitivity to antiretrovirals. Determining the type of HIV infecting a patient is essential for management. The aim of this study was to evaluate the ability of simple/rapid tests to differentiate between HIV-1 and/or HIV-2 infec...

journal_title：Journal of medical virology

authors： Gautheret-Dejean A,Bocobza J,Brunet S,Damond F,Plantier JC,Barin F

更新日期：2015-12-01 00:00:00

abstract：:Critical cases of coronavirus disease 2019 (COVID-19) are associated with a high risk of mortality. It remains unclear why patients with the same critical condition have different outcomes. We aimed to explore relevant factors that may affect the prognosis of critical COVID-19 patients. Six critical COVID-19 inpatient...

journal_title：Journal of medical virology

authors： Wei LL,Wang WJ,Chen DX,Xu B

更新日期：2020-11-01 00:00:00

abstract：:The question of whether booster doses are required to maintain long-term protection against hepatitis B virus (HBV) after primary vaccination remains to be determined. Thus, the aim of this study was to evaluate the immune memory responses to hepatitis B surface antigen (HBsAg) challenge in vaccinated individuals thro...

journal_title：Journal of medical virology

authors： do Livramento A,Schultz J,Batista KZ,Treitinger A,de Cordova CM,Spada C

更新日期：2014-10-01 00:00:00

abstract：:Replication of HIV-1 inside host cells is dependent on both viral and host factors. MicroRNAs are small noncoding RNAs that regulate protein synthesis. MicroRNAs may control viral replication either by directly targeting the viral genome or indirectly through cellular proteins that are required during the viral lifecy...

journal_title：Journal of medical virology

authors： Dubey RC,Alam NB,Gaur R

更新日期：2020-12-24 00:00:00

abstract：:Chronic hepatitis B patients with low pre-treatment HBeAg (and HBV-DNA) levels are more likely to respond to interferon-alpha therapy. In retrospect, this low level of HBeAg may have been reached just before the start of therapy. Pre-treatment changes in HBeAg levels were studied in 121 patients undergoing interferon-...

journal_title：Journal of medical virology

authors： Heijtink RA,Janssen HL,Hop WC,Osterhaus AD,Schalm SW

更新日期：2001-03-01 00:00:00

abstract：:To investigate whether the administration of IL-12 is effective against influenza virus infection, mice were intranasally administered IL-12 for three consecutive days and then infected with a non-lethal dose of the influenza virus. The IL-12-treated mice were more resistant to the virus than control mice with respect...

journal_title：Journal of medical virology

authors： Ishikawa H,Ino S,Sasaki H,Fukui T,Kohda C,Tanaka K

更新日期：2016-09-01 00:00:00

abstract：:The seroprevalence of hepatitis A antibodies in travellers attending London Travel Clinics increases with age and screening may eliminate the need for vaccination at present for approximately 40% of adults. The duration of protection by current hepatitis A vaccine(s) is still to be established. ...

journal_title：Journal of medical virology

authors： Zuckerman JN,Powell L

更新日期：1994-12-01 00:00:00

abstract：:Serial serum samples from 20 untreated patients with chronic hepatitis C virus (HCV) infection were tested for HCV RNA by a nested polymerase chain reaction assay using primers from the highly conserved 5' noncoding region to determine the relationship between hepatitis C viremia and the activity of liver disease duri...

journal_title：Journal of medical virology

authors： Cheung RC,Chan RT,Lok AS

更新日期：1993-12-01 00:00:00

abstract：:Little information is available on the impact of direct-acting antiviral (DAA) therapy on changes in liver fibrosis and steatosis. Liver stiffness (LS) and controlled attenuation parameter (CAP) values were evaluated using transient elastography. The study subjects were 214 elderly patients infected with HCV genotype ...

journal_title：Journal of medical virology

authors： Ogasawara N,Kobayashi M,Akuta N,Kominami Y,Fujiyama S,Kawamura Y,Sezaki H,Hosaka T,Suzuki F,Saitoh S,Suzuki Y,Arase Y,Ikeda K,Kobayashi M,Kumada H

更新日期：2018-02-01 00:00:00

abstract：:Hepatitis A infections still represent a major global health concern. During the past years, a transition pattern of the hepatitis A epidemiology was noted in many parts of the world. In Tunisia, there is not a recent survey on age-specific hepatitis A virus seroprevalence. This study aimed to investigate the seroprev...

journal_title：Journal of medical virology

authors： Ayouni K,Kharroubi G,Mallekh R,Hammami W,Marouani R,Mhamdi M,Ben Salah A,Triki H,Bettaieb J

更新日期：2020-09-28 00:00:00

abstract：:Predictive factors of HCV relapse after treatment with DAAs are poorly understood. In this study, we aimed to assess whether the residual viral load positivity observed during or at the end of treatment (EOT) has an impact on viral outcome. Blood samples were collected from 337 patients with genotypes (GT) 1a, 1b, 2, ...

journal_title：Journal of medical virology

authors： Visco-Comandini U,Lapa D,Lionetti R,Taibi C,Loiacono L,Montalbano M,Capobianchi MR,D'Offizi G,Garbuglia AR

更新日期：2018-07-01 00:00:00

abstract：:Cytomegalovirus (CMV) is the most common congenital infection in humans and a leading cause of sensorineural hearing loss. Ganciclovir (6 mg/kg twice daily for 42 days) has been shown to reduce hearing deterioration and is used in clinical practice. Vaccines and passive administration of antibody are being evaluated i...

journal_title：Journal of medical virology

authors： Kadambari S,Atkinson C,Luck S,Macartney M,Conibear T,Harrison I,Booth C,Sharland M,Griffiths PD

更新日期：2017-03-01 00:00:00

abstract：:The objective of this study was to determine the use of immune-complex dissociated (ICD) p24 antigen detection for the diagnosis and prognosis of HIV-1 infection in Ugandan children. Plasma collected prospectively from children born to HIV-1 infected Ugandan women was stored and later analyzed for the presence of neut...

journal_title：Journal of medical virology

authors： Guay LA,Hom DL,Kabengera SR,Piwowar-Manning EM,Kataaha P,Ndugwa C,Marum LH,Kalyesubula I,Jackson JB

更新日期：2000-12-01 00:00:00

abstract：:Ideally, long-term lamivudine therapy should not induce tyrosine-methionine-aspartate-aspartate (YMDD) mutants (reverse transcription [rt]; rt M204I/V) in patients with chronic hepatitis B. There is little or no information on the clinical features of patients who do not develop such mutants. We analyzed 368 patients ...

journal_title：Journal of medical virology

authors： Hashimoto Y,Suzuki F,Hirakawa M,Kawamura Y,Yatsuji H,Sezaki H,Hosaka T,Akuta N,Kobayashi M,Saito S,Suzuki Y,Kobayashi M,Arase Y,Ikeda K,Kumada H

更新日期：2010-04-01 00:00:00

abstract：:The specificity and neutralizing activity of antibodies against the major herpes simplex virus type 1 (HSV-1) glycoproteins were tested in serum samples of patients with a history of HSV-1 infection. By preabsorption of sera to preparations of native and denatured HSV-1 proteins, followed by immunoblotting and microne...

journal_title：Journal of medical virology

authors： Eing BR,Kühn JE,Braun RW

更新日期：1989-01-01 00:00:00

abstract：:Among 39,656 voluntary blood donors in Okinawa Prefecture, Japan, 115 (0.29%) were repeatedly reactive for antibody to hepatitis C virus (anti-HCV) by second generation (2nd-gen) passive hemagglutination assay (PHA). Positive serum samples were tested for anti-HCV using three different enzyme immunosorbent assays (ELI...

journal_title：Journal of medical virology

authors： Sakugawa H,Nakasone H,Nakayoshi T,Kinjo F,Saito A,Yakabi S,Zukeran H,Miyagi Y,Taira R,Koja K

更新日期：1995-08-01 00:00:00

abstract：:A cohort of 127 nursing home residents aged 60-98 years were vaccinated during the winter of 1985-86 with the A-Chile 1/83 (C), A-Philippines 2/82 (P), and B-USSR (B) commercial influenza vaccines. Before vaccination 40%, 23%, and 69% were susceptible to influenza Ac, Ap, and B, respectively [hemagglutinin inhibition ...

journal_title：Journal of medical virology

authors： Keren G,Segev S,Morag A,Zakay-Rones Z,Barzilai A,Rubinstein E

更新日期：1988-05-01 00:00:00

abstract：:Despite prolonged undetectable plasma viral load some HIV-1 infected patients have been reported to develop resistance-associated mutations leading to treatment failure. The mechanisms for this phenomenon and the point of origin for residual viral evolution are still not elucidated. In order to quantify cell-associate...

journal_title：Journal of medical virology

authors： Kupfer B,Matz B,Däumer MP,Roden F,Rockstroh JK,Qurishi N,Spengler U,Kaiser R

更新日期：2007-10-01 00:00:00

abstract：:Genotype II.4 noroviruses (NoVs) are a leading cause of epidemic acute gastroenteritis in children and adults worldwide. The prevalence of different NoV genotypes causing outbreaks and sporadic cases of acute gastroenteritis in the region of Valencia, Spain, during a 4-year period (2008-11) was investigated. NoVs were...

journal_title：Journal of medical virology

authors： Carmona-Vicente N,Fernández-Jiménez M,Ribes JM,Téllez-Castillo CJ,Khodayar-Pardo P,Rodríguez-Diaz J,Buesa J

更新日期：2015-04-01 00:00:00

abstract：:The various strains of human polyomavirus BK (BKV) show a marked heterogeneity in the non-coding control region (NCCR), which includes the origin of replication and the regulatory region for early and late transcription. A new BKV strain (DDP, U91605) was identified by direct detection and sequencing of PCR products o...

journal_title：Journal of medical virology

authors： Degener AM,Pietropaolo V,Di Taranto C,Jin L,Ameglio F,Cordiali-Fei P,Trento E,Sinibaldi L,Orsi N

更新日期：1999-08-01 00:00:00

abstract：:Little information about immunity to respiratory syncytial virus (RSV) and disease pathogenesis in elderly persons exists. Humoral immunity to RSV was assessed in 41 young, 56 healthy elderly, and 49 frail elderly adults by measuring baseline RSV specific IgG by enzyme immunoassay (EIA) and microneutralization assay (...

journal_title：Journal of medical virology

authors： Falsey AR,Walsh EE,Looney RJ,Kolassa JE,Formica MA,Criddle MC,Hall WJ

更新日期：1999-10-01 00:00:00

abstract：:Monoclonal antibodies were used for detecting varicella-zoster virus (VZV) by immunofluorescence (IF) in clinical specimens inoculated on shell vial cultures. Vesicles of 74 patients with varicella or herpes zoster-like eruptions were tested by this method and by conventional cell culture. Further diagnostic tests wer...

journal_title：Journal of medical virology

authors： Schirm J,Meulenberg JJ,Pastoor GW,van Voorst Vader PC,Schröder FP

更新日期：1989-05-01 00:00:00

abstract：:A sensitive and reproducible real-time PCR assay based on TaqMan technology was developed for the detection and quantitation of hepatitis B virus (HBV) DNA in serum, and compared with an "in-house" qualitative PCR assay. HBV DNA was measured in 125 serum samples from 76 hepatitis B patients, consisting of 22 patients ...

journal_title：Journal of medical virology

authors： Chen RW,Piiparinen H,Seppänen M,Koskela P,Sarna S,Lappalainen M

更新日期：2001-10-01 00:00:00

abstract：:The quantification of human immunodeficiency virus type 1 (HIV-1) RNA or hepatitis C virus (HCV) RNA has been facilitated by adapting a spin column procedure for sample preparation and the use of chemiluminescent detection of polymerase chain reaction (PCR) products in microtiter plate format. All materials were comme...

journal_title：Journal of medical virology

authors： Lin HJ,Tanwandee T,Hollinger FB

更新日期：1997-01-01 00:00:00

abstract：:Human herpesvirus 6 (HHV6) is a beta-herpesvirus capable of infecting several cell types from different origins. HHV6 is the etiological agent of exantem subitum and has been associated with several diseases, all characterized by an inflammatory response triggered by chemokines. We show that strain U1102 of HHV6 is ab...

journal_title：Journal of medical virology

authors： Caruso A,Favilli F,Rotola A,Comar M,Horejsh D,Alessandri G,Grassi M,Di Luca D,Fiorentini S

更新日期：2003-07-01 00:00:00

abstract：:The discovery of acyclovir marked the beginning of an exciting era in antiviral research. Early studies on the novel mode of action explained the selectivity of the compound and the remarkably narrow spectrum of activity against a subset of the herpesviruses. Throughout the past decade many clinical trials have demons...

journal_title：Journal of medical virology

authors： Darby G

更新日期：1993-01-01 00:00:00

abstract：:In order to analyse the relationships between enteroviral replication and the myocardial damage at the onset of chronic cardiac infection, 2 mouse strains with different degrees of immunological competence (NMRI nu/nu, DBA/2) were infected by a myocarditic Coxsackie virus B3 (CVB3-M1) variant. At 31 days post-inoculat...

journal_title：Journal of medical virology

authors： Andréoletti L,Hober D,Becquart P,Belaich S,Copin MC,Lambert V,Wattré P

更新日期：1997-06-01 00:00:00

abstract：:Annual outbreaks of seasonal influenza cause a substantial health burden. The aim of this study was to compare patient demographic/clinical data in two influenza patient groups presenting to hospital; those requiring O2 or critical care admission and those requiring less intensive treatment. The study was conducted fr...

journal_title：Journal of medical virology

authors： Dominic C,Welch C,Melzer M

更新日期：2020-07-31 00:00:00

abstract：:A pathogenic role of precore-defective mutation in the onset of fulminant hepatitis B has been suggested. However, precore-defective mutants do not always cause fulminant hepatitis B and are not always isolated from affected patients. These findings strongly suggest the presence of some additional important mutations ...

journal_title：Journal of medical virology

authors： Kaneko M,Uchida T,Moriyama M,Arakawa Y,Shikata T,Gotoh K,Mima S

更新日期：1995-11-01 00:00:00