Rapid development of genotypic resistance to lamivudine when combined with zidovudine in pregnancy.

abstract：:The detection of hepatitis B virus (HBV) DNA plays a critical role in determining the level of viral replication in HBV-infected patients. However, how to select appropriate HBV DNA detection method, low-sensitivity (ls) and hypersensitivity (hs) remains unclear. In this study, hepatitis B surface antigen (HBsAg), hep...

journal_title：Journal of medical virology

authors： Liu C,Wu W,Shang S,Huang E,Xun Z,Lin J,Chen T,Yang B,Chen J,Ou Q

更新日期：2019-02-01 00:00:00

abstract：:Alfa-fetoprotein (AFP) is used as a marker of early hepatocarcinogenesis. However, the impact of hepatitis B virus surface antigen (HBsAg) on this relationship in patients with HBV infection is not clear. The present study evaluated the relation between HBsAg and AFP levels at the initial visit in 1,610 untreated HBV ...

journal_title：Journal of medical virology

authors： Akuta N,Suzuki F,Kobayashi M,Hara T,Sezaki H,Suzuki Y,Hosaka T,Kobayashi M,Saitoh S,Ikeda K,Kumada H

更新日期：2014-01-01 00:00:00

abstract：:Inosine triphosphatase (ITPA) gene variants can protect against ribavirin (RBV)-induced anemia in patients treated for chronic hepatitis C. The aim of this study was to determine the relationship between genetic variants of ITPA polymorphism, anemia, RBV dose reduction, and treatment response in hepatitis C virus (HCV...

journal_title：Journal of medical virology

authors： El Raziky M,Zayed NA,Abdel Baki A,Mansour SA,Shahin RMH

更新日期：2017-10-01 00:00:00

abstract：:Cells from a leiomyosarcoma tumor (LMS-1) from a patient with the acquired immunodeficiency syndrome (AIDS) were explanted, cultured in vitro, and studied by phase-contrast microscopy for morphologic and growth characteristics, immunostaining for cell markers, EBER in situ hybridization and polymerase chain reaction f...

journal_title：Journal of medical virology

authors： Jenson HB,Montalvo EA,McClain KL,Ench Y,Heard P,Christy BA,Dewalt-Hagan PJ,Moyer MP

更新日期：1999-01-01 00:00:00

abstract：:From 10(1) to 10(6) TCID50 (mean tissue culture infective doses) per ml HSV I and II can be quantitatively recorded from vaginal tampons. Tampons and sterile cotton swabs are equally sensitive in recovering HSV I and II. Direct cotton swab cultures of the cervix and cervicovaginal tampon cultures from the same patient...

journal_title：Journal of medical virology

authors： Ekwo EE,Myers MG

更新日期：1978-01-01 00:00:00

abstract：:Twenty marmosets, male Callithrix jacchus, were used during this study. Fifteen of the marmosets were inoculated with 5,000 TCID50 of the attenuated XJC13 strain of Junin virus by intramuscular route and five were left as uninoculated controls. Animals were observed for a 420-day period. In order to carry out virologi...

journal_title：Journal of medical virology

authors： Avila MM,Frigerio MJ,Weber EL,Rondinone S,Samoilovich SR,Laguens RP,de Guerrero LB,Weissenbacher MC

更新日期：1985-01-01 00:00:00

abstract：:Immunocompromised individuals were tested for the presence of the human polyomaviruses JC (JCV) and BK (BKV) by the polymerase chain reaction (PCR). The use of appropriate primers in a nested PCR allowed the detection of both viruses simultaneously. Viruses were differentiated by restriction fragment length analysis o...

journal_title：Journal of medical virology

authors： Schätzl HM,Sieger E,Jäger G,Nitschko H,Bader L,Ruckdeschel G,Jäger G

更新日期：1994-02-01 00:00:00

abstract：:A novel real-time PCR assay system was developed to quantify the cytomegalovirus (CMV) genome load. The real-time PCR assay could detect from 6 to over 10(6) copies of CMV-DNA with a wide linear range. The virus load of immunocompromised patients with symptomatic CMV infections was quantified and compared to that of a...

journal_title：Journal of medical virology

authors： Tanaka N,Kimura H,Iida K,Saito Y,Tsuge I,Yoshimi A,Matsuyama T,Morishima T

更新日期：2000-04-01 00:00:00

abstract：:To evaluate the variation over time of seroreactivity to human papillomavirus type 11 (HPV-11) according to disease outcome, we selected a sample of 42 condyloma acuminatum patients from a group of subjects enrolled in a placebo-controlled trial of three alpha-interferon preparations administered parenterally for the ...

journal_title：Journal of medical virology

authors： Bonnez W,Da Rin C,Rose RC,Tyring SK,Reichman RC

更新日期：1993-04-01 00:00:00

abstract：:Sexually transmitted disease (STD) remains a major public health challenge in developed countries, exacerbated by the advent of the HIV epidemic. The objectives of this study were to assess the prevalence of serological markers of syphilis, HIV-1/2, HTLV-I/II, HBV, and HCV infections among immigrant sex workers in Mad...

journal_title：Journal of medical virology

authors： Gutiérrez M,Tajada P,Alvarez A,De Julián R,Baquero M,Soriano V,Holguín A

更新日期：2004-12-01 00:00:00

abstract：:The objective of the study was to assess the genotypic and phenotypic properties of 18 viral strains from human immunodeficiency virus-1 (HIV-1) positive patients and to identify subtype C isolates for vaccine design strategies. All the isolates were non-syncytium-inducing (NSI) in both the primary and MT-2 cell cultu...

journal_title：Journal of medical virology

authors： Treurnicht FK,Smith TL,Engelbrecht S,Claassen M,Robson BA,Zeier M,van Rensburg EJ

更新日期：2002-10-01 00:00:00

abstract：:Human herpes virus type 6 (HHV-6) infection is widespread in healthy individuals. The only definite disease association is with exanthem subitum in infants though the virus has been linked with a variety of other diseases including interstitial pneumonitis in bone marrow allograft recipients. In order to investigate t...

journal_title：Journal of medical virology

authors： Pitalia AK,Liu-Yin JA,Freemont AJ,Morris DJ,Fitzmaurice RJ

更新日期：1993-10-01 00:00:00

abstract：:Antigenic drift of the hemagglutinin (HA) and neuraminidase (NA) proteins of the influenza virus cause a decrease in vaccine efficacy. Since the information about the evolution of these viruses in Saudi is deficient so we investigated the genetic diversity of circulating H1N1 viruses. Nasopharyngeal aspirates/swabs co...

journal_title：Journal of medical virology

authors： Naeem A,Elbakkouri K,Alfaiz A,Hamed ME,Alsaran H,AlOtaiby S,Enani M,Alosaimi B

更新日期：2020-03-11 00:00:00

abstract：:Recently a conventional method for the laboratory diagnosis of human cytomegalovirus (HCMV) infection was improved by using centrifugation culture to enhance viral adsorption and by detecting HCMV early antigen and DNA. Comparison of the sensitivity of three rapid methods using commercial diagnostic reagents for the d...

journal_title：Journal of medical virology

authors： Li SB,Fong CK

更新日期：1990-02-01 00:00:00

abstract：:Potential risk factors for the development of hepatocellular carcinoma were analysed in 40 Caucasian patients with this malignancy. A higher proportion (14 of 40; 35%) had evidence of hepatitis C virus (HCV) infection than had evidence of either hepatitis B virus (HBV) carriage (17.5%) or alcohol abuse (30%). In all 1...

journal_title：Journal of medical virology

authors： Garson JA,Wicki AN,Ring CJ,Joller H,Zala G,Schmid M,Buehler H

更新日期：1992-10-01 00:00:00

abstract：:Previous investigations of fomite transmission have focused on the presence of pathogens on inanimate objects in clinical settings. There has been limited investigation of fomite transmission in non-clinical pediatric settings where there is a high prevalence of respiratory virus infections. Over a 5 week period, this...

journal_title：Journal of medical virology

authors： Gralton J,McLaws ML,Rawlinson WD

更新日期：2015-06-01 00:00:00

abstract：:Human herpes virus 8 (HHV 8) is recognized as the necessary cause of Kaposi sarcoma (KS) and in the recent past the human papillomavirus (HPV) has been linked to the development of cutaneous basal cell and squamous cell carcinomas. In a cross sectional study investigating Beta-HPV infections in skin lesions, an unexpe...

journal_title：Journal of medical virology

authors： Murahwa AT,Muchemwa FC,Duri K,Borok MZ,Kanyera RB,Manhanzva MT,Mapingure MP,Stray-Pedersen B

更新日期：2014-09-01 00:00:00

abstract：:Using the RT-PCR with primers that anneal to the 5' and the 3' extremities of the genome segments of bunyaviruses and internal primers that anneal to the S segment of Simbu serogroup viruses in a nested PCR it was possible to amplify the Oropouche virus (ORO) genome from the sera of three patients. These results show ...

journal_title：Journal of medical virology

authors： Moreli ML,Aquino VH,Cruz AC,Figueiredo LT

更新日期：2002-01-01 00:00:00

abstract：:Human sapoviruses (SaVs) are a common cause of the acute gastroenteritis epidemic worldwide, and SaV outbreaks and infections have become more frequent in recent years. Since the end of December, 2015 to December, 2016, 2 gastroenteritis outbreaks occurred in 2 kindergarten classes (outbreaks A and B) in the Baoan dis...

journal_title：Journal of medical virology

authors： Wang Md J,Li PhD Y,Kong Md X,Li PhD H,Zhang Ba Q,Jin PhD M,Wang PhD Y,Duan PhD Z

更新日期：2018-11-01 00:00:00

abstract：:To investigate whether the administration of IL-12 is effective against influenza virus infection, mice were intranasally administered IL-12 for three consecutive days and then infected with a non-lethal dose of the influenza virus. The IL-12-treated mice were more resistant to the virus than control mice with respect...

journal_title：Journal of medical virology

authors： Ishikawa H,Ino S,Sasaki H,Fukui T,Kohda C,Tanaka K

更新日期：2016-09-01 00:00:00

abstract：:During the period 2007-2008 several epizootics of Yellow fever with dead of monkeys occurred in southeastern Brasil, Paraguay, and northeastern Argentina. In 2008 after a Yellow fever outbreak an exhaustive prevention campaign took place in Argentina using 17D live attenuated Yellow fever vaccine. This vaccine is cons...

journal_title：Journal of medical virology

authors： Pires-Marczeski FC,Martinez VP,Nemirovsky C,Padula PJ

更新日期：2011-12-01 00:00:00

abstract：:Hepatitis A infections still represent a major global health concern. During the past years, a transition pattern of the hepatitis A epidemiology was noted in many parts of the world. In Tunisia, there is not a recent survey on age-specific hepatitis A virus seroprevalence. This study aimed to investigate the seroprev...

journal_title：Journal of medical virology

authors： Ayouni K,Kharroubi G,Mallekh R,Hammami W,Marouani R,Mhamdi M,Ben Salah A,Triki H,Bettaieb J

更新日期：2020-09-28 00:00:00

abstract：BACKGROUND AND AIM:Genotype 3b hepatitis C virus (HCV) infection represents approximately 50% of patients with genotype 3 in China. We compared the efficacy of sofosbuvir (SOF) plus ribavirin (RBV) in Chinese patients with genotype 3a and 3b HCV. METHODS:The analyzed data are from a phase 3, open-label study of SOF pl...

journal_title：Journal of medical virology

authors： Huang R,Rao H,Xie Q,Gao Z,Li W,Jiang D,Mo H,Massetto B,Stamm LM,Brainard DM,Wei L

更新日期：2019-07-01 00:00:00

abstract：:Polyomavirus BK (BKV) is a common human polyomavirus that rarely causes clinical symptoms in immunocompetent individuals. However, BK virus reactivation occurs in 20-40% of kidney transplant patients and 1-10% of cases present with BK virus-associated nephropathy (BKVN) and reduced kidney allograft survival. In this s...

journal_title：Journal of medical virology

authors： Girmanova E,Brabcova I,Bandur S,Hribova P,Skibova J,Viklicky O

更新日期：2011-08-01 00:00:00

abstract：:Studies have shown that swine HEV (sHEV) and rabbit HEV (rHEV) can experimentally infect rabbits and swine, respectively. However, no published data have documented isolating sHEV strains from rabbits in natural environment so far. To clarify the possibility of natural cross-species transmission of sHEV to rabbits, th...

journal_title：Journal of medical virology

authors： Liu L,Wang L,Xia J,Zhang Y,Zeng H,Liu P,Zou Q,Wang L,Zhuang H

更新日期：2016-04-01 00:00:00

abstract：:Hepatitis E virus (HEV), a positive-strand RNA agent, has been associated with enterically transmitted non-A, non-B hepatitis in Asia, Africa, and Mexico. To evaluate the role of HEV in an outbreak of hepatitis in Pakistan, we used immune electron microscopy to detect 1) antibody to HEV, for evidence of infection, and...

journal_title：Journal of medical virology

authors： Ticehurst J,Popkin TJ,Bryan JP,Innis BL,Duncan JF,Ahmed A,Iqbal M,Malik I,Kapikian AZ,Legters LJ

更新日期：1992-02-01 00:00:00

abstract：:HIV diagnosis at the point-of-care or in resource-limited settings poses considerable challenges due to time and cost limitations. Currently, nucleic acid-based tests are the only reliable method for diagnosing recent infections during the window period post-infection and pre-seroconversion, but these tests are only s...

journal_title：Journal of medical virology

authors： Curtis KA,Rudolph DL,Owen SM

更新日期：2009-06-01 00:00:00

abstract：:Human herpesvirus 8 (HHV-8) is the etiologic agent of Kaposi's sarcoma (KS). Several studies indicate horizontal HHV-8 transmission among children in areas where KS is endemic, but few studies have assessed acquisition of HHV-8 by children in low seroprevalence areas. Antibody screening was carried out for HHV-8 and E...

journal_title：Journal of medical virology

authors： Martro E,Bulterys M,Stewart JA,Spira TJ,Cannon MJ,Thacher TD,Bruns R,Pellett PE,Dollard SC

更新日期：2004-01-01 00:00:00

abstract：:In October 1977 an outbreak of acute infectious diarrhea occurred in an infant home in the city of Sapporo, Japan. Of 34 residents aged two to 20 months, 26 (77%) suffered from diarrhea. In ten of these patients the diarrhea was accompanied by vomiting. Electron microscopic examinations revealed typical calicivirus pa...

journal_title：Journal of medical virology

authors： Chiba S,Sakuma Y,Kogasaka R,Akihara M,Horino K,Nakao T,Fukui S

更新日期：1979-01-01 00:00:00

abstract：:Following widespread outbreaks of oyster-associated gastroenteritis in Australia during 1978 in which Norwalk virus was implicated as the causative agent, collaborative studies were undertaken between laboratories in Australia and the United States to confirm the etiology. Immune electron microscopy (IEM) techniques w...

journal_title：Journal of medical virology

authors： Grohmann GS,Greenberg HB,Welch BM,Murphy AM

更新日期：1980-01-01 00:00:00