Seroprevalence of hepatitis A virus infection in Central-West of Tunisia.

Abstract:

:Hepatitis A infections still represent a major global health concern. During the past years, a transition pattern of the hepatitis A epidemiology was noted in many parts of the world. In Tunisia, there is not a recent survey on age-specific hepatitis A virus seroprevalence. This study aimed to investigate the seroprevalence of hepatitis A virus infection in Central-West Tunisia, representative of regions with lowest socioeconomic level in the country, before vaccine implementation. Sera obtained from the blood samples of subjects were screened for the detection of hepatitis A virus. The seroprevalence was evaluated by detection of total antibodies to hepatitis A virus using commercially available immunoassay kits. A total of 1379 subjects, aged 5-75 years (mean age: 29.0 ± 17.3 years) were studied. The global anti-hepatitis A virus seroplevalence was 84.7% (95% confidence interval: [82.6-86.5]). A higher hepatitis A virus seroprevalence was showed in subjects aged 10-14 years compared to those aged less than 10 years (50.0% vs. 31.0%). In subjects aged 20-29 years, a rapid increase in the hepatitis A virus prevalence was noted; it reached 97.0%. The seroprevalence of anti-hepatitis A virus differed by zone of residence (81.1% in rural area vs. 72.4% in urban area, p = .005) and increased significantly with lower level of education (p = .019). There was no statistical significant seroprevalence difference between male and female: 84.2% versus 85.2%, respectively. Our study confirm the transition pattern of the hepatitis A virus endemicity in Tunisia from high to intermediate and provide an evaluation of the hepatitis A virus epidemiological situation before vaccine implementation.

journal_name

J Med Virol

authors

Ayouni K,Kharroubi G,Mallekh R,Hammami W,Marouani R,Mhamdi M,Ben Salah A,Triki H,Bettaieb J

doi

10.1002/jmv.26563

subject

Has Abstract

pub_date

2020-09-28 00:00:00

eissn

0146-6615

issn

1096-9071

pub_type

杂志文章
  • Prevalence of sexually transmitted pathogens associated with HPV infection in cervical samples in a Mexican population.

    abstract::Cervical cancer development has been mainly associated with persistent human papillomavirus (HPV) infections. However, HPV infection is unlikely to be sufficient to cause cervical cancer, and the contribution of other sexually transmitted infections (STIs) could be the determining factor for cervical lesion-progressio...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24278

    authors: Magaña-Contreras M,Contreras-Paredes A,Chavez-Blanco A,Lizano M,De la Cruz-Hernandez Y,De la Cruz-Hernandez E

    更新日期:2015-12-01 00:00:00

  • Human metapneumovirus-associated hospital admissions over five consecutive epidemic seasons: evidence for alternating circulation of different genotypes.

    abstract::Human metapneumovirus (hMPV) is a pathogen of the respiratory tract with a worldwide distribution. The purpose of this study was to identify hMPV as the cause of acute respiratory diseases in children admitted at Spedali Civili, a public hospital in Brescia, Italy. Eight hundred forty-six nasopharyngeal aspirate sampl...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23213

    authors: Apostoli P,Zicari S,Lo Presti A,Ciccozzi M,Ciotti M,Caruso A,Fiorentini S

    更新日期:2012-03-01 00:00:00

  • Inactivation of hepatitis A virus by heat treatment in aqueous solution.

    abstract::Hepatitis A virus infections have been reported recently among hemophilic patients in Italy and Germany, leading to speculation that infectious hepatitis A virus (HAV) might have been present in some factor VIII concentrates. In both cases, the implicated factor concentrates had been treated by a solvent/detergent met...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890410113

    authors: Murphy P,Nowak T,Lemon SM,Hilfenhaus J

    更新日期:1993-09-01 00:00:00

  • Cell cycle perturbation in the hepatocytes of HCV core transgenic mice following common bile duct ligation is associated with enhanced p21 expression.

    abstract::Hepatitis C virus (HCV) core protein has been reported to alter the cell cycle in vitro, but the data remain inconclusive, and in vitro experiments do not represent precisely events that occur in vivo, which may involve hepatic inflammation or regeneration. A group of double-transgenic mice carrying tetracycline trans...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21403

    authors: Chang ML,Chen TH,Chang MY,Yeh CT

    更新日期:2009-03-01 00:00:00

  • Relative frequency of human rotavirus VP4 (P) genotypes recovered over a ten-year period from South African children with diarrhea.

    abstract::The relative frequency and distribution of the VP4 (P) genotypes of 227 human rotavirus field strains were investigated in South Africa. The stool samples were collected between 1984-1993 from infants and young children with diarrhea at Ga-Rankuwa Hospital, Pretoria, South Africa. The RNA was extracted from stools, he...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890470102

    authors: Mphahlele MJ,Steele AD

    更新日期:1995-09-01 00:00:00

  • Recent trends in hepatitis A incidence in Brazil.

    abstract::Hepatitis A incidence has been decreasing in Brazil since child vaccination was implemented in 2014. This trend was interrupted by an outbreak among adult male in São Paulo in 2017. This study was outlined to estimate whether the increase of hepatitis A cases among adult men in Brazil was restricted to São Paulo. Case...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25694

    authors: De Oliveira TM,Vieira NSG,Sepp TDS,Souto FJD

    更新日期:2020-08-01 00:00:00

  • Seroprevalence of Kaposi's sarcoma-associated herpesvirus among men who have sex with men in Japan.

    abstract::Kaposi's sarcoma-associated herpesvirus (KSHV), the etiologic agent of Kaposi's sarcoma, causes malignancies frequently in patients with acquired immunodeficiency syndrome. In the United States and Europe, KSHV infection is common among men who have sex with men. However, the seroprevalence of KSHV among men who have ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23558

    authors: Katano H,Yokomaku Y,Fukumoto H,Kanno T,Nakayama T,Shingae A,Sugiura W,Ichikawa S,Yasuoka A

    更新日期:2013-06-01 00:00:00

  • Clinical performance of the HPV DNA Array genotyping assay in detection of CIN2+ lesions with BS GP5+/6+ MPG Luminex tested cervical samples.

    abstract::Human papillomavirus (HPV) detection is used for screening of cervical cancer and genotype-specific persistence has shown to be mandatory for dysplasia development. Aim of this study was to evaluate the clinical performance of HPV DNA Array for cervical intraepithelial neoplasia 2+ (CIN2+)  lesion detection. HPV DNA A...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25583

    authors: Pesic A,Krings A,Hempel M,Preyer R,Kaufmann AM

    更新日期:2020-01-01 00:00:00

  • Distribution of genital wart human papillomavirus genotypes in China: a multi-center study.

    abstract::Although it is understood that low-risk human papillomavirus (HPV) genotypes are associated with genital warts, there have been very few published studies reporting the genotype-specific prevalence of HPV among Chinese population. The aim of the study was to assess the prevalence of HPV genotypes in genital warts acro...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/jmv.23646

    authors: Chang L,Ci P,Shi J,Zhai K,Feng X,Colombara D,Wang W,Qiao Y,Chen W,Wu Y

    更新日期:2013-10-01 00:00:00

  • The effect of being diagnosed with human papillomavirus infection on women's sexual lives.

    abstract:PROBLEM:Objective studies that use validated questionnaires are needed to evaluate the changes in the sexual functions of women diagnosed with human papillomavirus (HPV) infection. METHOD OF STUDY:The study comprised 80 sexually active women diagnosed with a high-risk HPV infection. These patients were divided into fo...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25623

    authors: Alay I,Kaya C,Karaca I,Yildiz S,Baghaki S,Cengiz H,Ekin M,Yasar L

    更新日期:2020-08-01 00:00:00

  • A simple method for detection of a novel coronavirus (SARS-CoV-2) using one-step RT-PCR followed by restriction fragment length polymorphism.

    abstract::A novel coronavirus associated with acute respiratory disease (named SARS-CoV-2) is recently identified in Wuhan city, China, spread rapidly worldwide. Early identification of this novel coronavirus by molecular tools is critical for surveillance and control of the epidemic outbreak. We aimed to establish a simple met...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26171

    authors: Son HA,Hang DTT,Thuan ND,Quyen LTB,Thuong LTH,Nga VT,Quang LB,Hung TT,Son NT,Linh NT,Nam LV,Van Ba N,Tien TV,Quyet D,Van Luong H,Su HX

    更新日期:2020-11-01 00:00:00

  • Characterization of immune complexes containing cytomegalovirus-specific IgM antibodies following a kidney graft.

    abstract::In order to demonstrate the viral specificity of IgM-containing immune complexes (IgM-CIC) detected by a C1q assay in renal allograft recipients developing a CMV infection, a technique is described allowing: 1) the dissociation of IgM-CIC by action of an acid buffer, and 2) the characterization of the viral specificit...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890330312

    authors: Basson J,Tardy JC,Aymard M

    更新日期:1991-03-01 00:00:00

  • Human parainfluenza virus types 1-4 in hospitalized children with acute lower respiratory infections in China.

    abstract::Human parainfluenza viruses (HPIVs) are an important cause of acute lower respiratory tract infections (ALRTIs). HPIV-4, a newly identified virus, has been associated with severe ALRTIs recently. A total of 771 nasopharyngeal aspirate samples were collected from hospitalized children between March 2010 and February 20...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24580

    authors: Xiao NG,Duan ZJ,Xie ZP,Zhong LL,Zeng SZ,Huang H,Gao HC,Zhang B

    更新日期:2016-12-01 00:00:00

  • Impact on disease mortality of clinical, biological, and virological characteristics at hospital admission and overtime in COVID-19 patients.

    abstract::Little is known on the association between clinical factors and coronavirus disease 2019 (COVID-19) more than 15 days after diagnosis. We conducted a multicentric prospective cohort of COVID-19 hospitalized patients to describe clinical, biological, and virological characteristics at hospital admission and over time, ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26601

    authors: Yazdanpanah Y,French COVID cohort investigators and study group.

    更新日期:2020-10-15 00:00:00

  • Phylogenetic characterization of enterovirus 68 strains in patients with respiratory syndromes in Italy.

    abstract::Enterovirus 68 (EV-D68) was associated with mild to severe respiratory infections. In the last 4 years, circulation of different EV-D68 strains has been documented worldwide. In this study, the phylogenetic characterization of nine EV-D68 strains identified in patients in the 2010-2012 period and 12 additional EV-D68 ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23821

    authors: Piralla A,Girello A,Grignani M,Gozalo-Margüello M,Marchi A,Marseglia G,Baldanti F

    更新日期:2014-09-01 00:00:00

  • Seroprevalence of hepatitis A virus antibodies in Turkish and Moroccan children in Rotterdam.

    abstract::Seasonal fluctuations in hepatitis A have been observed in the Netherlands related to Turkish and Moroccan children after visiting their home countries. This study determined the prevalence and associated factors of hepatitis A virus (HAV) antibodies in Turkish and Moroccan children in Rotterdam. A random sample was t...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.10576

    authors: Richardus JH,Vos D,Veldhuijzen IK,Groen J

    更新日期:2004-02-01 00:00:00

  • Prevalence of genital, oral, and anal HPV infection among STI patients in Italy.

    abstract::Human papillomavirus (HPV) is a carcinogenic agent responsible for tumor development in many sexually involved tissues. We present a survey on the prevalence of HPV infection in a risk population for sexually transmitted infections (STIs). The studied population was formed by 125 STI clinic attendees, who took part in...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24746

    authors: Ciccarese G,Herzum A,Rebora A,Drago F

    更新日期:2017-06-01 00:00:00

  • Identification of a novel human papillomavirus type 16 E1 gene variant with potentially reduced oncogenicity.

    abstract::The human papillomavirus (HPV) 16 genome has been studied extensively, although no study has focused on the E1 gene that is implicated in viral DNA replication. After analyzing the E1 region of HPV 16 genomes in 429 cervical samples, 11.2% were found to contain a 63 nucleotides duplication in this region. Sequence ana...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21304

    authors: Sabol I,Matovina M,Gasperov NM,Grce M

    更新日期:2008-12-01 00:00:00

  • Molecular analysis of HPV 16 E6I/E6II spliced mRNAs and correlation with the viral physical state and the grade of the cervical lesion.

    abstract::The presence of HPV 16 E6*I/E6*II spliced transcripts, in cervical lesions of different grade, was analyzed to characterize the transcription pattern. The presence and amount of spliced transcripts were correlated with DNA viral markers such as E2/E6 ratio and physical state. The detection of HPV 16 E6*I/E6*II mRNAs w...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21496

    authors: Cricca M,Venturoli S,Leo E,Costa S,Musiani M,Zerbini M

    更新日期:2009-07-01 00:00:00

  • Cloning, expression, and immunogenicity of the assembly protein of varicella-zoster virus and detection of the products of open reading frame 33.

    abstract::Herpesviruses produce assembly proteins (AP) that act as scaffolding proteins for the assembly of the viral capsids. The products of the assemblin gene, which encodes both maturational protease and AP, have been established for herpes simplex virus type 1 (HSV-1) and human cytomegalovirus (CMV). We cloned an inframe O...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Garcia-Valcarcel M,Fowler WJ,Harper DR,Jeffries DJ,Layton GT

    更新日期:1997-12-01 00:00:00

  • Hepatitis C infection, Cognition, and inflammation in an Egyptian sample.

    abstract::Chronic hepatitis C (HCV) infection is associated with cognitive impairments which might be mediated through a secondary inflammatory cascade. Egypt has an unusually high prevalence of HCV monoinfections and is an ideal site for the study of the isolated effects of HCV infection. Therefore, in a hospital-based cross-s...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21879

    authors: Farag NH,Rashed HA,Hassan M,Darweesh A,Shehata M,Hassanein T,Mills PJ

    更新日期:2011-02-01 00:00:00

  • Effect of antiviral therapy on the immunohistochemical expression of bcl-xL and bax protein in patients with HBeAg-negative chronic hepatitis B.

    abstract::The effect of antiviral treatment on apoptosis in chronic hepatitis B (CHB) has not been clarified. We evaluated the hepatic immunohistochemical expression of the pro-apoptotic bax and the antiapoptotic bcl-xL protein in HBeAg-negative CHB patients before and after treatment. In our study we included 72 paired biopsie...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21780

    authors: Cholongitas E,Papatheodoridis GV,Manesis EK,Petraki K,Tiniakos D,Hadziyannis SJ

    更新日期:2011-07-01 00:00:00

  • Genotype-specific effects on left ventricular function in parvovirus B19-positive patients with dilated cardiomyopathy.

    abstract::Genotype-specific effects of parvovirus B19 (B19V) infections on left ventricular function in patients with dilated cardiomyopathy (DCM) have not been investigated so far. In this prospective clinical study, the prevalences of B19V genotypes in endomyocardial biopsies from patients presenting with inflammatory heart d...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.22187

    authors: Ruppert V,Meyer T,Balbach A,Richter A,Müller HH,Maisch B,Pankuweit S,German Heart Failure Network.

    更新日期:2011-10-01 00:00:00

  • Selection of drug-resistant HIV-1 during the early phase of viral decay is uncommon in treatment-naïve patients initiated on a three- or four-drug antiretroviral regimen including lamivudine.

    abstract::Therapy failure due to drug resistance development is a common phenomenon in HIV-infected patients. However, when the drug pressure leads to the earliest selection of drug-resistant HIV-1 populations is still unclear. In this study, the extent to which selection of the HIV-1 reverse transcriptase M184I/V mutations occ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21363

    authors: Bergroth T,Ekici H,Gisslén M,Loes SK,Goh LE,Freedman A,Lampe F,Johnson MA,Sönnerborg A

    更新日期:2009-01-01 00:00:00

  • MxA protein in capillary blood of children with viral infections.

    abstract::Capillary blood of febrile children was lysed by using a lysis buffer containing ascorbic acid. MxA quantitation was performed by an immunochemiluminescent assay. The MxA values were significantly higher in capillary blood of infants with viral infections due to adenovirus (n = 5), rotavirus (n = 15), or respiratory s...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Chieux V,Hober D,Chehadeh W,Harvey J,Alm G,Cousin J,Ducoulombier H,Wattre P

    更新日期:1999-12-01 00:00:00

  • Distribution of BK polyomavirus genotypes in Tunisian renal transplant recipients.

    abstract::BK polyomavirus (BKV) is a ubiquitous virus in humans that remains latent in the urogenital tract after a primary infection during childhood. The virus, which is reactivated frequently and excreted in urine, can cause nephropathy in renal transplant recipients. BKV sequences are classified into four subtypes (I-IV). S...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.22035

    authors: Boukoum H,Nahdi I,Foulongne V,Zallema D,Aloui S,Achour A,Segondy M,Aouni M

    更新日期:2011-04-01 00:00:00

  • Detection of hepatitis C virus RNA genome in liver tissue by nonisotopic in situ hybridization.

    abstract::A rapid technique for the detection of hepatitis C virus (HCV) RNA in liver section using nonisotopic in situ hybridization was described. Only 3 of the 10 patients seropositive for antibody to HCV and HCV RNA had detectable HCV RNA in the hepatocytes (1%, 2%, and 15% of cells positive). No specific signal was detecte...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890420313

    authors: Lau JY,Davis GL

    更新日期:1994-03-01 00:00:00

  • Reconnaissance of the candidate genes involved in the pathogenesis of human immunodeficiency virus and targeted by antiretroviral therapy.

    abstract::The expression levels of many genes change after treatment of human immunodeficiency virus (HIV)-infected subjects by antiretroviral drugs. High-throughput analysis of tremendous datasets led to the discovery of genes that are implicated in the treatment pathways. In this study, we performed a gene-enrichment analysis...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25549

    authors: Mozhgani SH,Zarei Ghobadi M,Behnam Rad M,Farzanehpour M,Behzadian F

    更新日期:2019-12-01 00:00:00

  • Low incidence and high titers of antibodies to hepatitis B virus X-protein in sera of Chinese patients with hepatocellular carcinoma.

    abstract::Sera of patients from China with hepatocellular carcinoma (HCC) were tested for the presence of HBc/HBe- and HBx antibodies by immunoblotting using recombinant MS2 or beta gal fusion proteins as substrate. Antibodies against HBx were detected in four out of 68 HBsAg positive and in one out of three HBsAg negative sera...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890250310

    authors: Liang XH,Stemler M,Will H,Braun R,Tang ZY,Schröder CH

    更新日期:1988-07-01 00:00:00

  • Polymerase chain reaction assay for hepatitis C virus RNA using a single tube for reverse transcription and serial rounds of amplification with nested primer pairs.

    abstract::A procedure is described for the detection of hepatitis C virus (HCV) RNA in blood by means of the polymerase chain reaction (PCR) in which the reverse transcription step and two rounds of amplification are carried out in a single tube. This results in fewer manipulations, reduced risk of contamination, and economy of...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890380312

    authors: Lin HJ,Shi N,Mizokami M,Hollinger FB

    更新日期:1992-11-01 00:00:00