ITPA gene polymorphism (94C>A) effects on ribavirin-induced anemia during therapy in Egyptian patients with chronic hepatitis C.

abstract：:The immunogenicity of the Russian cold-adapted (ca) donor stains, A/Leningrad (Len)/134/17/57 and A/Leningrad/134/47/57, and the US strain A/Ann Arbor (AA)/6/60-ca, were compared in BALB/c mice with their respective wild-type parental viruses. Each ca donor strain was less immunogenic than its wild-type parent. The va...

journal_title：Journal of medical virology

authors： Wareing MD,Watson JM,Brooks MJ,Tannock GA

更新日期：2001-09-01 00:00:00

abstract：:Respiratory syncytial (RSV) and parainfluenza (PIV) viruses are primary causes of acute bronchiolitis and wheezing illnesses in infants and young children. To further understand inflammation in the airways following infection, we tested for the presence of matrix metalloproteinases (MMP) and natural tissue inhibitors ...

journal_title：Journal of medical virology

authors： Elliott MB,Welliver RC Sr,Laughlin TS,Pryharski KS,LaPierre NA,Chen T,Souza V,Terio NB,Hancock GE

更新日期：2007-04-01 00:00:00

abstract：:Long-term treatment with retrotranscriptase (RT) inhibitors eventually leads to the development of drug resistance. Drug-related mutations occur naturally and these can be found in hepatitis B virus (HBV) carriers who have never received antiviral therapy. HBsAg are overlapped with RT domain, thus nucleot(s)ide analog...

journal_title：Journal of medical virology

authors： Fernández-Galindo DA,Sánchez-Ávila F,Bobadilla-Morales L,Gómez-Quiróz P,Bueno-Topete M,Armendáriz-Borunda J,Sánchez-Orozco LV

更新日期：2015-06-01 00:00:00

abstract：:We designed experiments to assess the effects of binding of the HSV-2 Fc receptor (FcR) to purified rabbit nonimmune IgG and purified Fc. Purified Fc (75 micrograms) or nonimmune IgG (100 micrograms) when bound to HSV-2 did not reduce infectivity but did protect the virions against thermal inactivation at 37 degrees C...

journal_title：Journal of medical virology

authors： Dowler KW,Veltri RW

更新日期：1984-01-01 00:00:00

abstract：:Little information is available on the impact of direct-acting antiviral (DAA) therapy on changes in liver fibrosis and steatosis. Liver stiffness (LS) and controlled attenuation parameter (CAP) values were evaluated using transient elastography. The study subjects were 214 elderly patients infected with HCV genotype ...

journal_title：Journal of medical virology

authors： Ogasawara N,Kobayashi M,Akuta N,Kominami Y,Fujiyama S,Kawamura Y,Sezaki H,Hosaka T,Suzuki F,Saitoh S,Suzuki Y,Arase Y,Ikeda K,Kobayashi M,Kumada H

更新日期：2018-02-01 00:00:00

abstract：:Interferon (IFN) alfa has been used widely for the treatment of chronic hepatitis C virus (HCV) infections but only a small number of patients treated have shown a sustained biochemical and virological response. Anti-envelope E1 and E2 antibody titers were assessed retrospectively before, during, and after treatment w...

journal_title：Journal of medical virology

authors： Depraetere S,Van Kerschaever E,Van Vlierberghe H,Elewaut A,Brouwer JT,Niesters HG,Schalm SW,Maertens G,Leroux-Roels G

更新日期：2000-02-01 00:00:00

abstract：:West Nile virus (WNV) activity has fluctuated in the south-central United States since its introduction. Seasonal outbreaks are common, with three in Oklahoma during 2003, 2007, and 2012. Morbidity and mortality rates vary during each outbreak. Long-term neurologic sequelae in association with West Nile virus disease ...

journal_title：Journal of medical virology

authors： Johnson MG,Adams J,McDonald-Hamm C,Wendelboe A,Bradley KK

更新日期：2015-10-01 00:00:00

abstract：:During the 1998-1999 influenza season, two distinct influenza B virus Yamagata group strains were isolated from the patients of a private clinic. Each responded differently to monoclonal antibodies (Mabs) 5H4 and 8B3 on staining, and hemagglutination inhibition and neutralizing tests. When the analysis of nucleotide s...

journal_title：Journal of medical virology

authors： Nakagawa N,Kubota R,Morikawa S,Nakagawa T,Baba K,Okuno Y

更新日期：2001-12-01 00:00:00

abstract：:Respiratory tract infections are a principal cause of illness and mortality in children worldwide and mostly caused by viruses. In this study, the epidemiology of 11 respiratory RNA viruses was investigated in a cohort of hospitalized children at a tertiary referral center in Riyadh from February 2008 to March 2009 us...

journal_title：Journal of medical virology

authors： Amer HM,Alshaman MS,Farrag MA,Hamad ME,Alsaadi MM,Almajhdi FN

更新日期：2016-06-01 00:00:00

abstract：:In 2000, we monitored the course and persistence of human papillomavirus (HPV) infection in 54 women who were HPV positive and free of any cytological disease using HPV-DNA genotyping with a linear array assay (baseline). The impact of HPV infection on development of cervical cytological abnormality (dyskaryosis) was ...

journal_title：Journal of medical virology

authors： Cuschieri KS,Whitley MJ,Cubie HA

更新日期：2004-05-01 00:00:00

abstract：:Monitoring of alphatorquevirus (torque teno virus [TTV]) DNA in plasma may prove to be useful to assess the net state of immune competence following allogeneic hematopoietic stem cell transplantation (allo-HSCT). There are scarce data published on the prevalence of beta (torque teno mini virus [TTMV]) and gammatorquev...

journal_title：Journal of medical virology

authors： Giménez E,Monzó C,Albert E,Fuentes-Trillo A,Seda E,Piñana JL,Hernández Boluda JC,Solano C,Chaves J,Navarro D

更新日期：2020-11-11 00:00:00

abstract：:Parainfluenza virus type 3 (Para 3) is an important childhood pathogen causing a significant amount of bronchiolitis and pneumonia in infants. Virus data were analysed over a twelve-year period (1978-1989), and a peak incidence of infection was observed in spring as in Houston, USA, unlike in the United Kingdom where ...

journal_title：Journal of medical virology

authors： de Silva LM,Cloonan MJ

更新日期：1991-09-01 00:00:00

abstract：:Patients attending the genitourinary medicine clinic at Watford General Hospital, UK, were examined for clinical signs of genital herpes infection. Genital swabs were taken from 194 patients (126 female, 68 male) who presented with genital ulceration or symptoms which were suggestive of genital herpes infection. Swabs...

journal_title：Journal of medical virology

authors： Slomka MJ,Emery L,Munday PE,Moulsdale M,Brown DW

更新日期：1998-06-01 00:00:00

abstract：:Using the RT-PCR with primers that anneal to the 5' and the 3' extremities of the genome segments of bunyaviruses and internal primers that anneal to the S segment of Simbu serogroup viruses in a nested PCR it was possible to amplify the Oropouche virus (ORO) genome from the sera of three patients. These results show ...

journal_title：Journal of medical virology

authors： Moreli ML,Aquino VH,Cruz AC,Figueiredo LT

更新日期：2002-01-01 00:00:00

abstract：:From 10(1) to 10(6) TCID50 (mean tissue culture infective doses) per ml HSV I and II can be quantitatively recorded from vaginal tampons. Tampons and sterile cotton swabs are equally sensitive in recovering HSV I and II. Direct cotton swab cultures of the cervix and cervicovaginal tampon cultures from the same patient...

journal_title：Journal of medical virology

authors： Ekwo EE,Myers MG

更新日期：1978-01-01 00:00:00

abstract：:Hepatitis C Virus (HCV) genotype 4 predominates in Middle East and Central Africa countries. Recently, it has become also prevalent in Southern European countries where it is thought to have been introduced through immigration and the movement of intravenous drug users. In Italy, the prevalence of genotype 4 is partic...

journal_title：Journal of medical virology

authors： Ciccozzi M,Equestre M,Costantino A,Marascio N,Quirino A,Lo Presti A,Cella E,Bruni R,Liberto MC,Focà A,Pisani G,Zehender G,Ciccaglione AR

更新日期：2012-10-01 00:00:00

abstract：:Hepatitis E virus (HEV) infection has become a global concern with high mortality rates among pregnant women, especially those in their third trimester of pregnancy. Estrogen plays an important role in mediating the body, regulating physiological and pathological processes. Estrogen is activated by binding to estrogen...

journal_title：Journal of medical virology

authors： Gong S,Hao X,Bi Y,Yang C,Wang W,Mickael HK,Zhang Y,Chen S,Qian Z,Huang F,Wei D,Yu W

更新日期：2020-10-31 00:00:00

abstract：:KI is a novel polyomavirus identified in the respiratory secretions of children with acute respiratory symptoms. Whether this reflects a causal role of the virus in the human respiratory disease remains to be established. To investigate the presence of KIV in the respiratory tissue, we examined 20 fresh lung cancer sp...

journal_title：Journal of medical virology

authors： Babakir-Mina M,Ciccozzi M,Campitelli L,Aquaro S,Lo Coco A,Perno CF,Ciotti M

更新日期：2009-03-01 00:00:00

abstract：:The human cytomegalovirus (HCMV), a member of the Herpesviridae, is the most frequent cause of congenital virus infections and a major cause of morbidity and mortality in immunocompromised patients. Due to the lack of an appropriate animal model, insight into the pathogenesis of HCMV infections originates primarily fr...

journal_title：Journal of medical virology

authors： Bissinger AL,Sinzger C,Kaiserling E,Jahn G

更新日期：2002-06-01 00:00:00

abstract：:Men who have sex with men (MSM) are an important risk group for human immunodeficiency virus (HIV) and at high-risk of herpesvirus infection. However, limited information on epidemiologic patterns of HHV8 and HSV2 among MSM is available in mainland China. A cross-sectional study of 486 participants was performed in Sh...

journal_title：Journal of medical virology

authors： Liu Z,Fang Q,Zuo J,Wang J,Chen Y,Minhas V,Wood C,He N,Zhang T

更新日期：2017-05-01 00:00:00

abstract：:Five methods were evaluated for the detection of adenovirus directly from nasopharyngeal aspirates (NPA), including conventional and rapid virus culture, two antigen detection tests, and the polymerase chain reaction (PCR). NPA specimens were obtained from 269 military conscripts suffering from an acute respiratory in...

journal_title：Journal of medical virology

authors： Räty R,Kleemola M,Melén K,Stenvik M,Julkunen I

更新日期：1999-09-01 00:00:00

abstract：:Coronavirus disease-2019 (COVID-19) infection and its severity can be explained by the concentration of glycosylated severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) viral particles in the lung epithelium, the concentration of glycosylated angiotensin-converting enzyme receptor 2 (ACE2) in the lung epithel...

journal_title：Journal of medical virology

authors： Brufsky A

更新日期：2020-07-01 00:00:00

abstract：:The rapid emergence of coronavirus disease 2019 (COVID-19) has necessitated the implementation of diverse pandemic control strategies throughout the world. To effectively control the spread of this disease, it is essential that it be diagnosed at an early stage so that patients can be reliably quarantined such that di...

journal_title：Journal of medical virology

authors： Zheng Z,Yao Z,Wu K,Zheng J

更新日期：2020-11-01 00:00:00

abstract：:The worldwide infection rate of herpesvirus is high, but the detailed prevalence in China, especially the central area, remains unclear. In the present study, the prevalence of herpes simplex virus (HSV), Epstein-Barr virus (EBV), and human cytomegalovirus (HCMV) was investigated in 303 healthy adults in Wuhan, a repr...

journal_title：Journal of medical virology

authors： Wen L,Qiu Y,Cheng S,Jiang X,Ma YP,Fang W,Wang W,Cui J,Ruan Q,Zhao F,Hu F,Luo MH

更新日期：2018-03-01 00:00:00

abstract：:The purpose of this study was to evaluate the use of dried blood spots stored on filter paper as a means to provide specimens for virologic surveillance for measles virus (MV) in situations when the reverse cold chain is not available. Two single-step RT-PCR assays were evaluated for sensitivity of detection of MV nuc...

journal_title：Journal of medical virology

authors： Katz RS,Premenko-Lanier M,McChesney MB,Rota PA,Bellini WJ

更新日期：2002-08-01 00:00:00

abstract：:Individuals infected with HIV have higher circulating Epstein-Barr virus (EBV) DNA load compared to healthy carriers. This study investigated whether level of spontaneous immunoglobulin secreting cells, one of the major hallmarks of HIV infection, is associated with an increase of EBV DNA load in PBMCs and the spontan...

journal_title：Journal of medical virology

authors： Ouedraogo DE,Tuaillon E,Rubbo PA,Bollore K,Foulongne V,Reynes J,Vendrell JP

更新日期：2014-01-01 00:00:00

abstract：:Shedding of herpes simplex virus type 1 (HSV-1) into saliva was studied in 83 patients with orofacial fractures. Infectious virus was isolated from 14 of 83 patients (16.8%) with no detectable herpetic lesion during hospitalization. Of the 83 patients, 44 (53%) had HSV-1 specific antibody. Virus shedding into saliva w...

journal_title：Journal of medical virology

authors： Kameyama T,Futami M,Nakayoshi N,Sujaku C,Yamamoto S

更新日期：1989-06-01 00:00:00

abstract：:HIV-1 infections due to non-B subtypes are increasing rapidly in number and spreading across Europe. The genetic nature of HIV-1 non-B variants containing subtype G sequences at the protease (PR)-coding region are described from 48 unrelated subjects living in Spain. Phylogenetic analyses of the HIV-1 reverse transcri...

journal_title：Journal of medical virology

authors： Holguín A,Alvarez A,Soriano V

更新日期：2005-03-01 00:00:00

abstract：:Immune correlates of protection against human cytomegalovirus (HCMV) infection are still debated. This study aimed to investigate which arm of the immune response plays a major role in protection against HCMV infection in kidney transplant recipients (n = 40) and heart transplant recipients (n = 12). Overall, patients...

journal_title：Journal of medical virology

authors： Lilleri D,Zelini P,Fornara C,Zavaglio F,Rampino T,Perez L,Gabanti E,Gerna G

更新日期：2018-10-01 00:00:00

abstract：:Co-infection with hepatitis delta virus (HDV) and hepatitis B virus (HBV) has been shown to be associated with a more severe form of acute and chronic hepatitis. Cloning and expression of recombinant HDV antigen (rHDAg) in Escherichiacoli are described. Using purified rHDAg, a cost-effective indirect anti-HDV enzyme-l...

journal_title：Journal of medical virology

authors： Shen L,Gu Y,Sun L,Yang Y,Wang F,Li Y,Bi S

更新日期：2012-03-01 00:00:00