Characterization of natural Epstein-Barr virus infection and replication in smooth muscle cells from a leiomyosarcoma.

abstract：:Puumala and Tula viruses are hantaviruses found in Europe and are associated with the rodents Clethrionomys glareolus and Microtus arvalis, respectively. Puumala virus is associated with the human disease nephropathia epidemica. In Austria, ten clinically diagnosed cases of nephropathia epidemica, presumably caused by...

journal_title：Journal of medical virology

authors： Bowen MD,Gelbmann W,Ksiazek TG,Nichol ST,Nowotny N

更新日期：1997-10-01 00:00:00

abstract：:Management of patients infected with high-risk HPV (hrHPV) despite normal colposcopy following abnormal cytology remains a clinical challenge. The aim of this study was to evaluate if, in that specific population, initial HPV 16 and HPV 18 viral loads are predictive of infection clearance over a 24-month follow-up. A ...

journal_title：Journal of medical virology

authors： Carcopino X,Henry M,Mancini J,Giusiano S,Boubli L,Olive D,Tamalet C

更新日期：2012-06-01 00:00:00

abstract：:To elucidate the relationship between the clinical severity of chronic liver disease and the precore mutations in hepatitis B e antigen (HBeAg)-negative hepatitis B virus (HBV) carriers, mutations were investigated in the precore region of HBV DNA in 20 chronic hepatitis B patients who seroconverted either spontaneous...

journal_title：Journal of medical virology

authors： Karasawa T,Aizawa Y,Zeniya M,Kuramoto A,Shirasawa T,Toda G

更新日期：1995-04-01 00:00:00

abstract：:Hepatitis E virus (HEV) infection has become a global concern with high mortality rates among pregnant women, especially those in their third trimester of pregnancy. Estrogen plays an important role in mediating the body, regulating physiological and pathological processes. Estrogen is activated by binding to estrogen...

journal_title：Journal of medical virology

authors： Gong S,Hao X,Bi Y,Yang C,Wang W,Mickael HK,Zhang Y,Chen S,Qian Z,Huang F,Wei D,Yu W

更新日期：2020-10-31 00:00:00

abstract：:Investigation of varicella-zoster virus (VZV) is important epidemiologically, and determination of its prevalence rate in human trigeminal ganglia is important to provide surveillance data. To date, studies on VZV detection in trigeminal ganglia have used specimens obtained from a relatively limited number of cadavers...

journal_title：Journal of medical virology

authors： Inoue H,Motani-Saitoh H,Sakurada K,Ikegaya H,Yajima D,Hayakawa M,Sato Y,Otsuka K,Kobayashi K,Nagasawa S,Iwase H

更新日期：2010-02-01 00:00:00

abstract：:At present eight hepatitis B virus (HBV) genotypes have been characterized: A to H. The most common genotype in Northern Europe is genotype A. So far there is no record of the specific HBV genotype distribution in Iceland. Iceland has a small population whose homogeneity has changed due to increasing migration during ...

journal_title：Journal of medical virology

authors： Björnsdottir TB,Stanzeit B,Sällberg M,Löve A,Hultgren C

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Human metapneumovirus (hMPV) is a recently detected virus, which can cause mild to severe respiratory tract infections. Through this study, we aimed to detail the outcomes of hMPV infections. MATERIALS/METHODS:Between January 2012 and November 2017, patients who had hMPV detected in nasopharyngeal or bronch...

journal_title：Journal of medical virology

authors： Keske Ş,Gümüş T,Köymen T,Sandıkçı S,Tabak L,Ergönül Ö

更新日期：2019-06-01 00:00:00

abstract：:False negativity in a commercial anti-HIV kit (IMx HIV-1/HIV-2 3rd Generation Plus (code 8B32) was investigated, and the kit that superseded it (IMx HIV-1/HIV-2 III Plus, code 8C98) was evaluated. In a comparison on 574 freshly collected anti-HIV-1-positive specimens, 97.2% were more reactive in 8C98 than in 8B32; 35....

journal_title：Journal of medical virology

authors： Parry JV,Perry KR,Harbour S,Burgess C,Mortimer PP,Blackburn NK,Martin D

更新日期：1998-10-01 00:00:00

abstract：:Human bocavirus (HBoV) is known to be associated with a variety of clinical manifestation including acute gastroenteritis (AGE). Despite their global prevalence, no data is available on the epidemiology of HBoV associated with AGE in South Africa (SA). Between April 2009 and April 2015, 3765 stool specimens were colle...

journal_title：Journal of medical virology

authors： Netshikweta R,Chidamba L,Nadan S,Taylor MB,Page NA

更新日期：2020-08-01 00:00:00

abstract：:The purpose of this study was to evaluate the use of dried blood spots stored on filter paper as a means to provide specimens for virologic surveillance for measles virus (MV) in situations when the reverse cold chain is not available. Two single-step RT-PCR assays were evaluated for sensitivity of detection of MV nuc...

journal_title：Journal of medical virology

authors： Katz RS,Premenko-Lanier M,McChesney MB,Rota PA,Bellini WJ

更新日期：2002-08-01 00:00:00

abstract：:Complete coding regions were sequenced for two new enterovirus genomes: EV-B93 previously identified by VP1 sequencing, derived from a child with acute flaccid paralysis in the Democratic Republic of Congo; and EV-C95 from a French soldier with acute gastroenteritis in Djibouti. The EV-B93 P1 had more than 30% nucleot...

journal_title：Journal of medical virology

authors： Junttila N,Lévêque N,Magnius LO,Kabue JP,Muyembe-Tamfum JJ,Maslin J,Lina B,Norder H

更新日期：2015-03-01 00:00:00

abstract：:Interleukin 6 (IL-6) is a pleiotropic cytokine with pivotal functions in the regulation of the biological responses of several target cells, including hepatocytes. Previous studies have shown that serum IL-6 levels are increased in hepatitis B patients. However, the role of IL-6 in modulating the anti-hepatitis B viru...

journal_title：Journal of medical virology

authors： Yang K,Guan S,Zhang H,Chen Z

更新日期：2019-05-01 00:00:00

abstract：:Co-infection with hepatitis delta virus (HDV) and hepatitis B virus (HBV) has been shown to be associated with a more severe form of acute and chronic hepatitis. Cloning and expression of recombinant HDV antigen (rHDAg) in Escherichiacoli are described. Using purified rHDAg, a cost-effective indirect anti-HDV enzyme-l...

journal_title：Journal of medical virology

authors： Shen L,Gu Y,Sun L,Yang Y,Wang F,Li Y,Bi S

更新日期：2012-03-01 00:00:00

abstract：:Early estimates of the prevalence of TTV viremia in healthy adults of developed countries were in the order of 1--10 %, while similar estimates in Third World countries were considerably higher. Using three different PCRs, TTV-related DNA was detected in serum from 180 out of the 201 Norwegian blood donors tested, ind...

journal_title：Journal of medical virology

authors： Huang LY,Oystein Jonassen T,Hungnes O,Grinde B

更新日期：2001-07-01 00:00:00

abstract：:Human parvovirus B19 commonly infects children, causing erythema infectiosum (fifth disease). However, there is a significant adult population which has not been exposed to the virus and, consequently, does not have protective antibody. Recent reports have associated B19 infection during pregnancy with fetal death, al...

journal_title：Journal of medical virology

authors： Clewley JP,Cohen BJ,Field AM

更新日期：1987-12-01 00:00:00

abstract：:Hepatitis B virus (HBV) genotypes impact treatment outcomes and disease progression. The current genotyping methods have limitations in patients with low HBV viral load. In this study, a more sensitive assay has been developed for determining the HBV genotype in HBV DNA suppressed patients. Fifty-five serum samples fr...

journal_title：Journal of medical virology

authors： Liu Y,May L,Liu X,Martin R,Svarovskaia E,Gaggar A,Mo H,Feierbach B

更新日期：2020-07-01 00:00:00

abstract：:The putative interferon sensitivity determining region (ISDR) in the NS5a region of the hepatitis C virus (HCV) was analyzed in 13 interferon alpha (IFN-alpha) treated patients representing genotypes 1a, 1b, and 2b. These patients had previously been followed longitudinally during treatment with respect to viral load ...

journal_title：Journal of medical virology

authors： Odeberg J,Yun Z,Sönnerborg A,Weiland O,Lundeberg J

更新日期：1998-09-01 00:00:00

abstract：:The various strains of human polyomavirus BK (BKV) show a marked heterogeneity in the non-coding control region (NCCR), which includes the origin of replication and the regulatory region for early and late transcription. A new BKV strain (DDP, U91605) was identified by direct detection and sequencing of PCR products o...

journal_title：Journal of medical virology

authors： Degener AM,Pietropaolo V,Di Taranto C,Jin L,Ameglio F,Cordiali-Fei P,Trento E,Sinibaldi L,Orsi N

更新日期：1999-08-01 00:00:00

abstract：:The human cytomegalovirus (HCMV), a member of the Herpesviridae, is the most frequent cause of congenital virus infections and a major cause of morbidity and mortality in immunocompromised patients. Due to the lack of an appropriate animal model, insight into the pathogenesis of HCMV infections originates primarily fr...

journal_title：Journal of medical virology

authors： Bissinger AL,Sinzger C,Kaiserling E,Jahn G

更新日期：2002-06-01 00:00:00

abstract：:A total of 82 samples from patients with cervical cancer (Group 1) and 50 samples from patients with other genital diseases (Group 2) were collected in Gansu, China. All 132 samples were tested for HPV DNA with a typing kit that can detect 21 types of HPV, and also tested for neutralizing antibodies against HPV-16, -1...

journal_title：Journal of medical virology

authors： Wu X,Zhang C,Feng S,Liu C,Li Y,Yang Y,Gao J,Li H,Meng S,Li L,Zhang Y,Hu X,Wu X,Lin L,Li X,Wang Y

更新日期：2009-04-01 00:00:00

abstract：:No data on antiviral response of HBV genotypes E-H are available so far although these HBV genotypes contribute significantly to the global HBV burden. Of 49 patients with HBV genotypes E-H, 23 received interferon (IFN)-alpha, 12 nucleos(t)ide analogues and 14 patients were untreated. HBV genotype was determined by di...

journal_title：Journal of medical virology

authors： Erhardt A,Göbel T,Ludwig A,Lau GK,Marcellin P,van Bömmel F,Heinzel-Pleines U,Adams O,Häussinger D

更新日期：2009-10-01 00:00:00

abstract：:Human herpes virus type 6 (HHV-6) infection is widespread in healthy individuals. The only definite disease association is with exanthem subitum in infants though the virus has been linked with a variety of other diseases including interstitial pneumonitis in bone marrow allograft recipients. In order to investigate t...

journal_title：Journal of medical virology

authors： Pitalia AK,Liu-Yin JA,Freemont AJ,Morris DJ,Fitzmaurice RJ

更新日期：1993-10-01 00:00:00

abstract：:The study characterized the virological patterns and the resistance-associated substitutions (RASs) in patients with failure to IFN-free regimens enrolled in the real-life setting. All 87 consecutive HCV patients with failed IFN-free regimens, observed at the laboratory of the University of Campania, were enrolled. Al...

journal_title：Journal of medical virology

authors： Starace M,Minichini C,De Pascalis S,Macera M,Occhiello L,Messina V,Sangiovanni V,Adinolfi LE,Claar E,Precone D,Stornaiuolo G,Stanzione M,Ascione T,Caroprese M,Zampino R,Parrilli G,Gentile I,Brancaccio G,Iovinella V,

更新日期：2018-05-01 00:00:00

abstract：:Knowledge of the current epidemiology of chronic liver disease in Italy is mostly obsolete and fragmentary for the lack of up-to-date consistent data. In 2001, a 6-month prevalence study was undertaken in 79 hospitals to assess the characteristics of chronic liver disease in Italy. Both prevalent and incident cases we...

journal_title：Journal of medical virology

authors： Sagnelli E,Stroffolini T,Mele A,Almasio P,Coppola N,Ferrigno L,Scolastico C,Onofrio M,Imparato M,Filippini P

更新日期：2005-04-01 00:00:00

abstract：:Saffold viruses (SAFV) have been discovered recently and they are classified into Theilovirus species in genus Cardiovirus in the Picornaviridae family. SAFV, especially those belonging to the genotype 2, have been difficult to propagate in laboratory cell lines. This study describes the successful isolation of an eff...

journal_title：Journal of medical virology

authors： Blomqvist S,Lappalainen M,Paananen A,Ylipaasto P,Roivainen M

更新日期：2012-09-01 00:00:00

abstract：:Capillary blood of febrile children was lysed by using a lysis buffer containing ascorbic acid. MxA quantitation was performed by an immunochemiluminescent assay. The MxA values were significantly higher in capillary blood of infants with viral infections due to adenovirus (n = 5), rotavirus (n = 15), or respiratory s...

journal_title：Journal of medical virology

authors： Chieux V,Hober D,Chehadeh W,Harvey J,Alm G,Cousin J,Ducoulombier H,Wattre P

更新日期：1999-12-01 00:00:00

abstract：:In this meta-analysis, we evaluated the diagnostic role of Epstein-Barr virus deoxyribonucleic acid detection and quantitation in the serum of pediatric and young adult patients with infectious mononucleosis. The primary outcome of this meta-analysis was the sensitivity and specificity of Epstein-Barr virus (EBV) deox...

journal_title：Journal of medical virology

authors： Jiang SY,Yang JW,Shao JB,Liao XL,Lu ZH,Jiang H

更新日期：2016-05-01 00:00:00

abstract：:Variation at the IL-28B locus was recently reported to be a significant predictive factor of viral response to pegylated-interferon plus ribavirin combination therapy against chronic hepatitis C. Predictive factors for the effect of therapy, including IL-28B polymorphism rs8099917 and viral and clinical factors were i...

journal_title：Journal of medical virology

authors： Hashimoto Y,Ochi H,Abe H,Hayashida Y,Tsuge M,Mitsui F,Hiraga N,Imamura M,Takahashi S,Nelson Hayes C,Ohishi W,Kubo M,Tsunoda T,Kamatani N,Nakamura Y,Chayama K

更新日期：2011-06-01 00:00:00

abstract：:Sapovirus, a member of the family Caliciviridae is one of the major causative agents of viral gastroenteritis affecting all age group. Sapovirus was detected in 25 of 917 stool specimens from infants and children with acute gastroenteritis in a Children Hospital in Dhaka City, Bangladesh during 2004-2005. All fecal sp...

journal_title：Journal of medical virology

authors： Dey SK,Phan TG,Nguyen TA,Nishio O,Salim AF,Yagyu F,Okitsu S,Ushijima H

更新日期：2007-05-01 00:00:00

abstract：:The effect of HHV-6 strain A infection on the expression of Epstein-Barr virus- (EBV-) encoded growth transformation-associated genes in two EBV-positive Burkitt lymphoma cell lines, Akata and P3HR-3, was investigated. The results indicate that HHV-6A upregulates the expression of the latent membrane protein LMP-1 in ...

journal_title：Journal of medical virology

authors： Cuomo L,Trivedi P,de Grazia U,Calogero A,D'Onofrio M,Yang W,Frati L,Faggioni A,Rymo L,Ragona G

更新日期：1998-07-01 00:00:00