Induction of interleukin 6 impairs the anti-HBV efficiency of IFN-α in human hepatocytes through upregulation of SOCS3.

abstract：:Serial blood and faecal samples were collected from patients and family contacts during an outbreak of hepatitis A in a village and tested by a solid-phase competitive type radioimmunoassay for hepatitis A antigen and hepatitis A antibody. The amount and duration of excretion of hepatitis A antigen was correlated with...

journal_title：Journal of medical virology

authors： Frösner GG,Overby LR,Flehmig B,Gerth HJ,Haas H,Decker RH,Ling CM,Zuckerman AJ,Frösner HR

更新日期：1977-01-01 00:00:00

abstract：:Noroviruses (NoVs) are a leading cause of acute gastroenteritis outbreaks and sporadic cases of diarrhea in industrialized countries. To study the prevalence and genetic diversity of NoVs in Guatemala, stool specimens were collected from hospitalized and ambulatory patients presenting with diarrhea (≥3 loose or liquid...

journal_title：Journal of medical virology

authors： Estévez A,Arvelo W,Hall AJ,López MR,López B,Reyes L,Moir JC,Gregoricus N,Vinjé J,Parashar UD,Lindblade KA

更新日期：2013-07-01 00:00:00

abstract：:In order to shed light on the mode of HTLV-I infection by mother-to-child transmission, we examined sera of school children in a highly endemic town on two separate occasions at a 6-year interval. The carrier rates in ages 15-17, 8.7 and 2.1%, were significantly higher than that in ages 6-8, 1.7 and 0.4%, in studies. ...

journal_title：Journal of medical virology

authors： Sugiyama H,Doi H,Yamaguchi K,Tsuji Y,Miyamoto T,Hino S

更新日期：1986-11-01 00:00:00

abstract：:Rhinovirus (RV) is a common respiratory viral infection linked to worsening of chronic respiratory diseases including cystic fibrosis (CF) and asthma. RV was tested by RT-PCR in samples (n = 465) collected from the upper (nasal swab, oropharyngeal suction, and sputum) and lower (bronchoalveolar washings) respiratory t...

journal_title：Journal of medical virology

authors： Stelzer-Braid S,Liu N,Doumit M,D'Cunha R,Belessis Y,Jaffe A,Rawlinson WD

更新日期：2017-08-01 00:00:00

abstract：:Hantaviruses is an emerging infectious disease. Although HCPS has been reported in several regions of Brazil, more cases of HCPS have recently been reported in Minas Gerais than in any other state. In 2009, we analyzed 27 samples presenting antibodies against hantaviruses. These samples originated from 688 symptomatic...

journal_title：Journal of medical virology

authors： de Araujo J,Duré AI,Negrão R,Ometto T,Thomazelli LM,Durigon EL

更新日期：2015-05-01 00:00:00

abstract：:BK polyomavirus (BKV) is a ubiquitous virus in humans that remains latent in the urogenital tract after a primary infection during childhood. The virus, which is reactivated frequently and excreted in urine, can cause nephropathy in renal transplant recipients. BKV sequences are classified into four subtypes (I-IV). S...

journal_title：Journal of medical virology

authors： Boukoum H,Nahdi I,Foulongne V,Zallema D,Aloui S,Achour A,Segondy M,Aouni M

更新日期：2011-04-01 00:00:00

abstract：:In total 1,525 blood serum samples were collected in October, 2013 in Russian Asia from people who reside in territories that are at high risk for emergence of influenza viruses with pandemic potential. Presence of antibodies to influenza viruses in the sera was tested in hemagglutination inhibition test. None of the ...

journal_title：Journal of medical virology

authors： Ilyicheva T,Abdurashitov M,Durymanov A,Susloparov I,Goncharova N,Kolosova N,Mikheev V,Ryzhikov A

更新日期：2016-01-01 00:00:00

abstract：:A solid-phase radioimmunoassay (RIA) for the detection of hepatitis B e antigen (HBeAg) and antibody (anti-HBe) was developed. The RIA was approximately 1,000-fold more sensitive than rheophoresis for HBeAg, and approximately 6,000-fold more sensitive than rheophoresis for anti-HBe. Generally, less than one-fifth of h...

journal_title：Journal of medical virology

authors： Mushahwar IK,Overby LR,Frosner G,Deinhardt F,Ling CM

更新日期：1978-01-01 00:00:00

abstract：:Thirty-two cerebrospinal fluid (CSF) samples from eighteen patients with confirmed herpes simplex encephalitis (HSE) were assayed by an indirect enzyme-linked immunosorbent assay (ELISA) for the presence of viral antigens. The results are expressed as an antigen ratio distinguishing between herpes simplex virus (HSV) ...

journal_title：Journal of medical virology

authors： Bos CA,Olding-Stenkvist E,Wilterdink JB,Scheffer AJ

更新日期：1987-02-01 00:00:00

abstract：:Hepatitis C virus (HCV) particles can be classified into two major fractions according to their floating density in serum. However, the genomic heterogeneity of each fraction and the relationship between this viral characteristic and interferon (IFN) response in patients with chronic hepatitis are not known. In this s...

journal_title：Journal of medical virology

authors： Sakai A,Kaneko S,Matsushita E,Kobayashi K

更新日期：1998-05-01 00:00:00

abstract：:To investigate whether the administration of IL-12 is effective against influenza virus infection, mice were intranasally administered IL-12 for three consecutive days and then infected with a non-lethal dose of the influenza virus. The IL-12-treated mice were more resistant to the virus than control mice with respect...

journal_title：Journal of medical virology

authors： Ishikawa H,Ino S,Sasaki H,Fukui T,Kohda C,Tanaka K

更新日期：2016-09-01 00:00:00

abstract：:GB virus-B (GBV-B) is the virus most closely related to hepatitis C virus (HCV). Thus, we have used GBV-B infection of tamarins, which develop acute hepatitis following experimental infection, as a surrogate model to study protective immunity. As challenge virus, we first produced a GBV-B pool from an infected tamarin...

journal_title：Journal of medical virology

authors： Bukh J,Engle RE,Govindarajan S,Purcell RH

更新日期：2008-01-01 00:00:00

abstract：:Dengue virus (DV) infection can result in either a mild febrile illness known as dengue fever (DF) or a life-threatening disease called dengue hemorrhagic fever (DHF). DHF is more prevalent in patients undergoing secondary DV infection. This observation has led to the hypothesis that DHF may be the result of immune re...

journal_title：Journal of medical virology

authors： Spain-Santana TA,Marglin S,Ennis FA,Rothman AL

更新日期：2001-10-01 00:00:00

abstract：:With multiple virus epicenters, COVID-19 has been declared a pandemic by the World Health Organization. Consequently, many countries have implemented different policies to manage this crisis including curfew and lockdown. However, the efficacy of individual policies remains unclear with respect to COVID-19 case develo...

journal_title：Journal of medical virology

authors： Khosrawipour V,Lau H,Khosrawipour T,Kocbach P,Ichii H,Bania J,Mikolajczyk A

更新日期：2020-07-01 00:00:00

abstract：:The relationships between host immune factors and HIV-1 disease progression are still in dispute. The RANTES SNPs exhibit distinct ethnic distribution and are associated with different effects on the course of HIV infection. Therefore, impact of RANTES gene polymorphism on HIV-1 transmission and progression needs to b...

journal_title：Journal of medical virology

authors： Rathore A,Chatterjee A,Sivarama P,Yamamoto N,Singhal PK,Dhole TN

更新日期：2008-07-01 00:00:00

abstract：:Elevated telomerase activity is observed in about 90% of human cancers. This activity correlates strictly with human telomerase reverse transcriptase (hTERT). Previously, it was shown that the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) induced telomerase activity in nasopharyngeal carcinoma cells. In ...

journal_title：Journal of medical virology

authors： Ding L,Li L,Yang J,Zhou S,Li W,Tang M,Shi Y,Yi W,Cao Y

更新日期：2007-08-01 00:00:00

abstract：:Influenza A/H3N2 viruses are associated with severe epidemics. Antiviral resistance and continued antigenic drift are the major concerns regarding prophylaxis and treatment of influenza. The objectives of this study were to investigate the prevalence and frequency of antiviral drug resistance in influenza A/H3N2 virus...

journal_title：Journal of medical virology

authors： Cai J,Wang X,Zhao B,Yao W,Wang X,Zhu Q,Zeng M

更新日期：2014-06-01 00:00:00

abstract：:In eight patients with biopsy-confirmed chronic active hepatitis (CAH), hepatitis B e antigen (HBeAg) levels and DNA polymerase (DNA-P) activity were assayed three times a week for six weeks and once a week for another six weeks. HBeAg levels were rather constant, whereas DNA-P activity fluctuated. No correlation was ...

journal_title：Journal of medical virology

authors： Heijtink RA,van der Waart M,Weimar W,Schalm SW,Masurel N

更新日期：1980-01-01 00:00:00

abstract：:Platelet distribution width (PDW) is a readily available blood test involving calculations performed by automated blood analyzers. Crimean-Congo hemorrhagic fever (CCHF) may exhibit a severe profile with fatal hemorrhaging or else present with a mild clinical process. The purpose of our study was to investigate the im...

journal_title：Journal of medical virology

authors： Yilmaz H,Yilmaz G,Menteşe A,Kostakoğlu U,Karahan SC,Köksal İ

更新日期：2016-11-01 00:00:00

abstract：:Human metapneumovirus (hMPV) is considered an important cause of acute respiratory infections. hMPV can cause morbidity in hematopoietic stem cell transplant recipients and recent research has demonstrated that it is an important virus in patients admitted to hospital with respiratory infections and suspected of havin...

journal_title：Journal of medical virology

authors： Souza JS,Watanabe A,Carraro E,Granato C,Bellei N

更新日期：2013-03-01 00:00:00

abstract：:Human parechoviruses (HPeVs) are prevalent in young children; however, their effects are incompletely understood. We investigated the prevalence, genotype distribution, and phylogeny of HPeVs in individuals with diarrhea (n = 430) and healthy controls (n = 93) by the analysis of stool specimens collected from July 201...

journal_title：Journal of medical virology

authors： Chen X,Shi T,Huang J,Xiao G,Huang J,Xiong Y,Li X,Chen H,Zheng X,Yu S,Chen Q

更新日期：2018-09-01 00:00:00

abstract：:To characterize the state of dual infection with hepatitis B virus (HBV) and hepatitis C virus (HCV), HBV-DNA and HCV-RNA levels were determined by spot hybridization or polymerase chain reaction in the sera of patients who were positive for both hepatitis B surface antigen and HCV antibody. Among 27 patients who show...

journal_title：Journal of medical virology

authors： Koike K,Yasuda K,Yotsuyanagi H,Moriya K,Hino K,Kurokawa K,Iino S

更新日期：1995-02-01 00:00:00

abstract：:Influenza A(H1N1)pdm09 virus pandemic struck India in 2009 and continues to cause outbreaks in its post-pandemic phase. Diminutive information is available about influenza A(H1N1)pdm09 from central India. This observational study presents epidemiological and molecular findings for the period of 6 years. Throat swab sa...

journal_title：Journal of medical virology

authors： Sahu M,Singh N,Shukla MK,Potdar VA,Sharma RK,Sahare LK,Ukey MJ,Barde PV

更新日期：2018-03-01 00:00:00

abstract：:In the ongoing coronavirus disease 2019 (COVID-19) pandemic, one potential cause of concern is that some discharged COVID-19 patients are testing positive again for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA. To better understand what is happening and to provide public health policy planners and ...

journal_title：Journal of medical virology

authors： Han Z,Battaglia F,Terlecky SR

更新日期：2020-07-01 00:00:00

abstract：:This investigation is in continuation with the earlier studies on diarrhea epidemic due to rotavirus, that occurred at Jawhar western India, among tribal children during Dec 2000-Jan 2001 published by National Institute of Virology, Pune. Three rotavirus strains were isolated in cell culture from fecal specimens of af...

journal_title：Journal of medical virology

authors： Awachat PS,Kelkar SD

更新日期：2005-09-01 00:00:00

abstract：:To investigate the genetic diversity, time origin, and evolutionary history of the 2019-nCoV outbreak in China and Thailand, a total of 12 genome sequences of the virus with known sampling date (24 December 2019 and 13 January 2020) and geographic location (primarily Wuhan city, Hubei Province, China, but also Bangkok...

journal_title：Journal of medical virology

authors： Li X,Zai J,Wang X,Li Y

更新日期：2020-04-01 00:00:00

abstract：:The plaque reduction neutralization test (PRNT) has been used routinely in serological studies with such arenaviruses as Junin, Machupo, and Parana. However, difficulties have been encountered in using the PRNT for LCM virus, while conflicting views have been expressed about the reliability and efficacy of the test wi...

journal_title：Journal of medical virology

authors： Tomori O,Johnson KM,Kiley MP,Elliott LH

更新日期：1987-05-01 00:00:00

abstract：:The burden of herpes zoster may be related to patients' immunity, although this has not been studied extensively. This hypothesis was tested in a matched case-control study of patients with herpes zoster who sought treatment at one of seven university hospitals in Korea from January 1, 2007, to December 31, 2010. Pati...

journal_title：Journal of medical virology

authors： Choi WS,Kwon SS,Lee J,Choi SM,Lee JS,Eom JS,Sohn JW,Choeng HJ

更新日期：2014-03-01 00:00:00

abstract：:Recently, several clusters of hepatitis A have been observed among hemophiliacs linked to factor VIII concentrates treated for virus inactivation solely with the solvent/detergent (S/D) method, a procedure that does not affect nonenveloped viruses such as the hepatitis A virus (HAV). A new outbreak of hepatitis A in s...

journal_title：Journal of medical virology

authors： Chudy M,Budek I,Keller-Stanislawski B,McCaustland KA,Neidhold S,Robertson BH,Nübling CM,Seitz R,Löwer J

更新日期：1999-02-01 00:00:00

abstract：:Hepatitis E is endemic in India. It was recently noted that although all the Indian human hepatitis E virus (HEV) isolates (1976-2001) were placed in genotype I, the swine HEV recovered from western India (2000) belonged to genotype IV. This was in contrast to reports from the United States and Taiwan wherein both hum...

journal_title：Journal of medical virology

authors： Arankalle VA,Chobe LP,Walimbe AM,Yergolkar PN,Jacob GP

更新日期：2003-03-01 00:00:00