MxA protein in capillary blood of children with viral infections.

Abstract:

:Capillary blood of febrile children was lysed by using a lysis buffer containing ascorbic acid. MxA quantitation was performed by an immunochemiluminescent assay. The MxA values were significantly higher in capillary blood of infants with viral infections due to adenovirus (n = 5), rotavirus (n = 15), or respiratory syncytial virus (n = 28), than in capillary whole blood from infants with bacterial infections (n = 6) and healthy control patients (n = 20). A strong correlation was found between the MxA values in capillary whole blood and peripheral whole blood (r' = 0.86, P < 0.0001, n = 48). The MxA values found at these two sites were compared with the levels of IFN-alpha obtained by a dissociation enhanced lanthanide fluoroimmunoassay. A correlation between these two values was found. The results show that the combination of collection of blood by finger prick and specific immunochemiluminescent assay for MxA protein measurement may be of value for the diagnosis of viral infections in children.

journal_name

J Med Virol

authors

Chieux V,Hober D,Chehadeh W,Harvey J,Alm G,Cousin J,Ducoulombier H,Wattre P

keywords:

subject

Has Abstract

pub_date

1999-12-01 00:00:00

pages

547-51

issue

4

eissn

0146-6615

issn

1096-9071

pii

10.1002/(SICI)1096-9071(199912)59:4<547::AID-JMV20

journal_volume

59

pub_type

杂志文章
  • DNA of mouse mammary tumor virus-like virus is present in human tumors influenced by hormones.

    abstract::Mouse mammary tumor virus (MMTV) is a hormonally regulated, oncogenic virus of mice. MMTV-like virus DNA has previously been detected in human breast cancers, liver disease, and liver cancers. It is hypothesized that local hormonal effects might be of primary importance in determining MMTV-like virus detection in huma...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21754

    authors: Johal H,Faedo M,Faltas J,Lau A,Mousina R,Cozzi P,Defazio A,Rawlinson WD

    更新日期:2010-05-01 00:00:00

  • Rapid detection of varicella-zoster virus in clinical specimens using monoclonal antibodies on shell vials and smears.

    abstract::Monoclonal antibodies were used for detecting varicella-zoster virus (VZV) by immunofluorescence (IF) in clinical specimens inoculated on shell vial cultures. Vesicles of 74 patients with varicella or herpes zoster-like eruptions were tested by this method and by conventional cell culture. Further diagnostic tests wer...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890280102

    authors: Schirm J,Meulenberg JJ,Pastoor GW,van Voorst Vader PC,Schröder FP

    更新日期:1989-05-01 00:00:00

  • ACE2, TMPRSS2, and Furin variants and SARS-CoV-2 infection in Madrid, Spain.

    abstract::It has been suggested that some individuals may present genetic susceptibility to SARS-CoV-2 infection, with particular research interest in variants of the ACE2 and TMPRSS2 genes, involved in viral penetration into cells, in different populations and geographic regions, although insufficient information is currently ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26319

    authors: Torre-Fuentes L,Matías-Guiu J,Hernández-Lorenzo L,Montero-Escribano P,Pytel V,Porta-Etessam J,Gómez-Pinedo U,Matías-Guiu JA

    更新日期:2021-02-01 00:00:00

  • Human bocavirus isolated from children with acute respiratory tract infections in Korea, 2010-2011.

    abstract::Human bocavirus (HBoV) was first recognized in respiratory samples in 2005. The clinical importance of HBoV infection remains unclear. This report describes the clinical features and molecular phylogeny of HBoV isolates in children with acute respiratory infections. Nasopharyngeal aspirates were obtained from 1,528 ch...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23880

    authors: Ahn JG,Choi SY,Kim DS,Kim KH

    更新日期:2014-12-01 00:00:00

  • Temporal distribution of human rotavirus serotypes 1,2,3, and 4 in Venezuelan children with gastroenteritis during 1979-1989.

    abstract::The temporal distribution and clinical severity of rotavirus VP7 serotypes 1, 2, 3, and 4 recovered from 427 Venezuelan children with acute gastroenteritis over a period of 11 years were studied. Rotavirus VP7 serotype was established by ELISA serotyping in 298 (69.78%) of the specimens while the serotype of the remai...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890340202

    authors: White L,García D,Boher Y,Blanco M,Pérez M,Romer H,Flores J,Pérez-Schael I

    更新日期:1991-06-01 00:00:00

  • Human herpesvirus-6 (HHV-6)-associated necrotizing encephalitis in Griscelli's syndrome.

    abstract::We report a male caucasian German pediatric patient of no Arab or Mediterranean ancestry with virus associated CNS lesions in Griscelli's syndrome (GS; McKusick No. 214450). The boy presented with recurrent infections, and meningitis with subsequent progressive signs of increased intracranial pressure leading to death...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9071(199711)53:3<306::aid-jmv21

    authors: Wagner M,Müller-Berghaus J,Schroeder R,Sollberg S,Luka J,Leyssens N,Schneider B,Krueger GR

    更新日期:1997-11-01 00:00:00

  • Clinical manifestations of death with severe fever and thrombocytopenia syndrome: A meta-analysis and systematic review.

    abstract::Severe hemorrhagic fever disease is caused by severe fever with thrombocytopenia syndrome virus (SFTSV) infection, which belongs to the Phlebovirus genus in the Bunyaviridae family. A comprehensive literature search of PubMed, Web of Science, Embase, Cochrane Library, Chinese National Knowledge Infrastructure database...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26518

    authors: Wang X,Ren X,Ge Z,Cui S,Wang L,Chen Z,Tian D

    更新日期:2020-09-15 00:00:00

  • Prevalence of WU and KI polyomaviruses in plasma, urine, and respiratory samples from renal transplant patients.

    abstract::WU and KI polyomaviruses (WUPyV, KIPyV) have been detected in respiratory, blood, stool, and lymphoid tissue, but not in urine samples. PCR based detection revealed higher frequency in immunocompromised individuals. In this study the prevalence of WUPyV and KIPyV was analyzed in respiratory, urine, and blood samples f...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.22083

    authors: Csoma E,Mészáros B,Asztalos L,Kónya J,Gergely L

    更新日期:2011-07-01 00:00:00

  • Quantitative analysis of HBV DNA level and HBeAg titer in hepatitis B surface antigen positive mothers and their babies: HBeAg passage through the placenta and the rate of decay in babies.

    abstract::It is well documented that perinatal transmission is the major cause of chronic HBV infection in China. However, the mechanisms of HBV perinatal transmission are not defined clearly. It is not known whether hepatitis B e antigen can cross the human placenta, and the rate of HBeAg decay in babies with and without HBV b...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.10493

    authors: Wang Z,Zhang J,Yang H,Li X,Wen S,Guo Y,Sun J,Hou J

    更新日期:2003-11-01 00:00:00

  • Dynamic study of HBsAg and HBeAg in saliva samples from patients with hepatitis B infection: diagnostic and epidemiological significance.

    abstract::Analysis of 505 cases history of patients among men with viral hepatitis demonstrates that HBV infected patients represent 68.9% of the total and that a non-parenteral rate of transmission is the most likely means of hepatitis B infection. Saliva and serum testing for the presence of specific HBV markers (HBsAg, HBeAg...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/1096-9071(200008)61:4<433::aid-jmv4>3.0.co

    authors: Zhevachevsky NG,Nomokonova NY,Beklemishev AB,Belov GF

    更新日期:2000-08-01 00:00:00

  • Detection of human papillomavirus in esophageal carcinoma.

    abstract::The aim of the study was to assess the prevalence of human papillomavirus (HPV) in the esophagus in the coastal region of Eastern Guangdong, Southern China, an area with a high incidence of esophageal carcinoma. Fresh surgical resection esophageal specimens were obtained from 176 esophageal carcinoma patients admitted...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.10219

    authors: Shen ZY,Hu SP,Lu LC,Tang CZ,Kuang ZS,Zhong SP,Zeng Y

    更新日期:2002-11-01 00:00:00

  • Human herpesvirus-6 modulates RANTES production in primary human endothelial cell cultures.

    abstract::Human herpesvirus 6 (HHV6) is a beta-herpesvirus capable of infecting several cell types from different origins. HHV6 is the etiological agent of exantem subitum and has been associated with several diseases, all characterized by an inflammatory response triggered by chemokines. We show that strain U1102 of HHV6 is ab...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.10416

    authors: Caruso A,Favilli F,Rotola A,Comar M,Horejsh D,Alessandri G,Grassi M,Di Luca D,Fiorentini S

    更新日期:2003-07-01 00:00:00

  • HCV RNA in patients with chronic hepatitis C treated with interferon-alpha.

    abstract::In order to assess the efficacy of interferon-alpha on hepatitis C viral RNA in patients with chronic hepatitis C, we analyzed the levels of HCV RNA in sera and liver tissues of 16 patients pre- and posttreatment using a semiquantitative polymerase chain reaction method. Fifteen of 16 patients were positive for anti-H...

    journal_title:Journal of medical virology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1002/jmv.1890400114

    authors: Liang TJ,Rustgi V,Galun E,Blum HE

    更新日期:1993-05-01 00:00:00

  • Association of hepatitis E virus with an outbreak of hepatitis in Pakistan: serologic responses and pattern of virus excretion.

    abstract::Hepatitis E virus (HEV), a positive-strand RNA agent, has been associated with enterically transmitted non-A, non-B hepatitis in Asia, Africa, and Mexico. To evaluate the role of HEV in an outbreak of hepatitis in Pakistan, we used immune electron microscopy to detect 1) antibody to HEV, for evidence of infection, and...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890360205

    authors: Ticehurst J,Popkin TJ,Bryan JP,Innis BL,Duncan JF,Ahmed A,Iqbal M,Malik I,Kapikian AZ,Legters LJ

    更新日期:1992-02-01 00:00:00

  • Coxsackievirus B1 reveals strain specific differences in plasmacytoid dendritic cell mediated immunogenicity.

    abstract::Enterovirus infections are usually mild but can also cause severe illnesses and play a role in chronic diseases, such as cardiomyopathies and type 1 diabetes. Host response to the invading virus can markedly modulate the course of the infection, and this response varies between individuals due to the polymorphism of i...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23903

    authors: Hämäläinen S,Nurminen N,Ahlfors H,Oikarinen S,Sioofy-Khojine AB,Frisk G,Oberste MS,Lahesmaa R,Pesu M,Hyöty H

    更新日期:2014-08-01 00:00:00

  • Significance of postnatal mother-to-child transmission of human T-lymphotropic virus type-I on the development of adult T-cell leukemia/lymphoma.

    abstract::In order to shed light on the mode of HTLV-I infection by mother-to-child transmission, we examined sera of school children in a highly endemic town on two separate occasions at a 6-year interval. The carrier rates in ages 15-17, 8.7 and 2.1%, were significantly higher than that in ages 6-8, 1.7 and 0.4%, in studies. ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890200307

    authors: Sugiyama H,Doi H,Yamaguchi K,Tsuji Y,Miyamoto T,Hino S

    更新日期:1986-11-01 00:00:00

  • Polymerase chain reaction assay for hepatitis C virus RNA using a single tube for reverse transcription and serial rounds of amplification with nested primer pairs.

    abstract::A procedure is described for the detection of hepatitis C virus (HCV) RNA in blood by means of the polymerase chain reaction (PCR) in which the reverse transcription step and two rounds of amplification are carried out in a single tube. This results in fewer manipulations, reduced risk of contamination, and economy of...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890380312

    authors: Lin HJ,Shi N,Mizokami M,Hollinger FB

    更新日期:1992-11-01 00:00:00

  • Detection of human cytomegalovirus early and late antigen and DNA production in cell culture and the effects of dimethyl sulfoxide, dexamethasone, and DNA inhibitors on early antigen induction.

    abstract::Recently a conventional method for the laboratory diagnosis of human cytomegalovirus (HCMV) infection was improved by using centrifugation culture to enhance viral adsorption and by detecting HCMV early antigen and DNA. Comparison of the sensitivity of three rapid methods using commercial diagnostic reagents for the d...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890300204

    authors: Li SB,Fong CK

    更新日期:1990-02-01 00:00:00

  • Expression profiles of genes associated with viral entry in HCV-infected human liver.

    abstract::Recent studies have demonstrated that several cellular factors are involved in entry of hepatitis C virus (HCV) into host cells. Detailed gene expression profiles of these factors in HCV-infected livers have not been reported for humans. Transcriptional levels of LDL receptor (LDLR), CD81, scavenger receptor class B t...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.22042

    authors: Nakamuta M,Fujino T,Yada R,Aoyagi Y,Yasutake K,Kohjima M,Fukuizumi K,Yoshimoto T,Harada N,Yada M,Kato M,Kotoh K,Taketomi A,Maehara Y,Nakashima M,Enjoji M

    更新日期:2011-05-01 00:00:00

  • Emergence of adamantane-resistant influenza A(H3N2) viruses in Hong Kong between 1997 and 2006.

    abstract::Resistance to adamantanes for treating influenza A(H3N2) has increased dramatically, worldwide, over the past 5 years. A comprehensive 10-year data set on the rise of adamantane-resistance in Hong Kong is reported. Nucleotide sequences encoding the M2-ion channel of influenza A(H3N2) were obtained from 281 H3N2 isolat...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21155

    authors: Tang JW,Ngai KL,Wong JC,Lam WY,Chan PK

    更新日期:2008-05-01 00:00:00

  • A new cluster of hepatitis A infection in hemophiliacs traced to a contaminated plasma pool.

    abstract::Recently, several clusters of hepatitis A have been observed among hemophiliacs linked to factor VIII concentrates treated for virus inactivation solely with the solvent/detergent (S/D) method, a procedure that does not affect nonenveloped viruses such as the hepatitis A virus (HAV). A new outbreak of hepatitis A in s...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9071(199902)57:2<91::aid-jmv1>3

    authors: Chudy M,Budek I,Keller-Stanislawski B,McCaustland KA,Neidhold S,Robertson BH,Nübling CM,Seitz R,Löwer J

    更新日期:1999-02-01 00:00:00

  • Hepatitis C virus infection of mononuclear cells from peripheral blood and liver infiltrates in chronically infected patients.

    abstract::The mechanisms underlying chronicity of hepatitis C virus (HCV) infection are poorly understood, but the importance of impaired viral clearance by the immune system has been suggested. The prevalence of HCV infection of peripheral blood mononuclear cells (PBMC) was in investigated in 34 persistently infected patients ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890470112

    authors: Zignego AL,De Carli M,Monti M,Careccia G,La Villa G,Giannini C,D'Elios MM,Del Prete G,Gentilini P

    更新日期:1995-09-01 00:00:00

  • Colposcopy, punch biopsy, in situ DNA hybridization, and the polymerase chain reaction in searching for genital human papillomavirus (HPV) infections in women with normal PAP smears.

    abstract::To assess the prevalence of HPV infection in the genital tracts of women with normal PAP smears, a random series of 109 women was reexamined using colposcopy, a further PAP smear, and punch biopsies taken from the cervix (in 33 cases), vagina (212 cases), and anus (20 cases). The biopsy material was examined using rou...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890310404

    authors: Syrjänen S,Saastamoinen J,Chang FJ,Ji HX,Syrjänen K

    更新日期:1990-08-01 00:00:00

  • Evaluation of an immunochromatography method for rapid detection of noroviruses in clinical specimens in Thailand.

    abstract::Norovirus (NoV) is a causative agent of gastroenteritis in children and adults worldwide. Although reverse transcription-polymerase chain reaction (RT-PCR) has been accepted as the standard method for diagnosis of NoV infection, it requires well-trained personnel and sophisticated equipments. Performance of a commerci...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21916

    authors: Thongprachum A,Khamrin P,Chaimongkol N,Malasao R,Okitsu S,Mizuguchi M,Maneekarn N,Ushijima H

    更新日期:2010-12-01 00:00:00

  • Evaluation of HTLV-1 HBZ and proviral load, together with host IFN λ3, in pathogenesis of HAM/TSP.

    abstract::Human T-cell lymphotropic virus 1 (HTLV-1) is associated with two progressive diseases: HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukemia/lymphoma (ATLL). Although HTLV-1 proviral load (PVL) has been introduced as a risk factor for these diseases' progression, it is not suff...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24721

    authors: Mozhgani SH,Jaberi N,Rezaee SA,Bustani R,Jazayeri SM,Akbarin MM,Milani S,Tarokhian H,Norouzi M

    更新日期:2017-06-01 00:00:00

  • Establishing diagnostic criteria for occult hepatitis B virus infections in community based populations.

    abstract::Present diagnostic criteria for occult hepatitis B virus (HBV) infection requires blood or liver samples to test positive for at least two HBV DNA targets in hepatitis B surface antigen (HBsAg) negative individuals. These criteria were derived from studies involving referred or selected patient populations. The object...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23813

    authors: Minuk GY,Huynh C,Uhanova J,Osiowy C

    更新日期:2014-01-01 00:00:00

  • Differential IgG avidity to rubella virus structural proteins.

    abstract::Avidity maturation of IgG antibody responses directed against the structural proteins of rubella virus (E1, E2, and C) as well as whole rubella virus (RV) was assessed at sequential time intervals in 7 individuals following serologically confirmed wild rubella infection. Individual structural proteins were purified fr...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890360310

    authors: Mauracher CA,Mitchell LA,Tingle AJ

    更新日期:1992-03-01 00:00:00

  • Detection and typing of human papillomavirus in biopsy and cytological specimens by polymerase chain reaction and restriction enzyme analysis: a method suitable for semiautomation.

    abstract::Screening for high-risk human papillomavirus (HPV) types allows the detection of women at a high risk of cervical squamous carcinomas, thereby defining a subset of patients targeted for more intensive screening and follow-up. Thirty-four cervical biopsy specimens and isolated cells from cervical smears of normal women...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(SICI)1096-9071(199602)48:2<161::AID-JMV8>

    authors: Adams V,Moll C,Schmid M,Rodrigues C,Moos R,Briner J

    更新日期:1996-02-01 00:00:00

  • Reactivation of human herpesvirus 6 by infection of human herpesvirus 7.

    abstract::We have attempted to reactivate human herpesvirus 6 (HHV-6) by infection with HHV-7 using childhood exanthem subitum patients in vitro. Peripheral blood mononuclear cells (PBMCs) were collected from children who had a history of exanthem subitum(ES) by HHV-6 and were infected by human herpesvirus 7 (HHV-7) in vitro. T...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9071(200003)60:3<284::aid-jmv6>

    authors: Tanaka-Taya K,Kondo T,Nakagawa N,Inagi R,Miyoshi H,Sunagawa T,Okada S,Yamanishi K

    更新日期:2000-03-01 00:00:00

  • HIV-1 variability and progression to AIDS: a longitudinal study.

    abstract::HIV-1 replicative activity and its relation to the clinical and immunological evolution of infection was studied in a group of 150 HIV-1 seropositive Italian i.v. drug abusers over a 1 year period. HIV-1 was isolated from 90 (60%) subjects; two groups of isolates were distinguished, according to replicative activity "...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890320411

    authors: Fiore JR,Calabró ML,Angarano G,De Rossi A,Fico C,Pastore G,Bianchi LC

    更新日期:1990-12-01 00:00:00