HCV RNA in patients with chronic hepatitis C treated with interferon-alpha.

abstract：:Antibodies to herpes simplex virus and Epstein-Barr virus were sought in the sera of 33 patients with endoscopically proved duodenal ulcer and 33 healthy controls. Neither the prevalence nor the antibody levels to both viruses were significantly different between the two groups. These results suggest that herpes virus...

journal_title：Journal of medical virology

authors： Kottaridis SD,Mihas TA,Goula I,Mihas AA

更新日期：1989-11-01 00:00:00

abstract：:Regulatory T cells (T(reg)) provide a balance to immune T cell activation thereby protecting the body from pathogen-induced immunopathology. Several persistent viruses induce T(reg) that subvert protective immune mechanisms and promote viral persistence. Epstein-Barr virus (EBV) generally infects children subclinicall...

journal_title：Journal of medical virology

authors： Wingate PJ,McAulay KA,Anthony IC,Crawford DH

更新日期：2009-05-01 00:00:00

abstract：:At present eight hepatitis B virus (HBV) genotypes have been characterized: A to H. The most common genotype in Northern Europe is genotype A. So far there is no record of the specific HBV genotype distribution in Iceland. Iceland has a small population whose homogeneity has changed due to increasing migration during ...

journal_title：Journal of medical virology

authors： Björnsdottir TB,Stanzeit B,Sällberg M,Löve A,Hultgren C

更新日期：2005-12-01 00:00:00

abstract：:Analysis of the HIV-1 V3 quasispecies present in an individual at the time of seroconversion was carried out. The polymerase chain reaction (PCR) was used to amplify proviral HIV-1 DNA extracted from peripheral blood mononuclear cells from a patient who was viraemic (p24 = 15 pg/ml) and had an equivocal HIV-1 antibody...

journal_title：Journal of medical virology

authors： Ait-Khaled M,Emery VC

更新日期：1993-12-01 00:00:00

abstract：:It has been reported that low-plasma cytomegalovirus (CMV) DNA loads are associated with an increased risk of overall mortality in allogeneic hematopoietic stem cell transplantation (allo-HSCT). Utilizing a conservative strategy for initiation of preemptive antiviral therapy (>1500 IU/mL), we characterized the virolog...

journal_title：Journal of medical virology

authors： Talaya A,Giménez E,Piñana JL,Albert E,Hernández-Boluda JC,Pérez A,Torres I,Solano C,Navarro D

更新日期：2019-06-01 00:00:00

abstract：:The study characterized the virological patterns and the resistance-associated substitutions (RASs) in patients with failure to IFN-free regimens enrolled in the real-life setting. All 87 consecutive HCV patients with failed IFN-free regimens, observed at the laboratory of the University of Campania, were enrolled. Al...

journal_title：Journal of medical virology

authors： Starace M,Minichini C,De Pascalis S,Macera M,Occhiello L,Messina V,Sangiovanni V,Adinolfi LE,Claar E,Precone D,Stornaiuolo G,Stanzione M,Ascione T,Caroprese M,Zampino R,Parrilli G,Gentile I,Brancaccio G,Iovinella V,

更新日期：2018-05-01 00:00:00

abstract：:Recent studies have suggested a pathogenic role of human parvovirus B19 (B19) in the development of acute fulminant liver failure in children. The hypothesis was based on the detection of B19 DNA in 8 of 10 explanted livers of children requiring liver transplantation. In the present study, explanted livers from 43 adu...

journal_title：Journal of medical virology

authors： Eis-Hübinger AM,Reber U,Abdul-Nour T,Glatzel U,Lauschke H,Pütz U

更新日期：2001-10-01 00:00:00

abstract：:A viable virus could not be recovered from a mutant murine cytomegalovirus (MCMV) BAC in which the M34 ORF had been deleted (BACDeltaM34). In contrast, an M34 mutant virus (RcM34), in which the M34 ORF was interrupted by transposon insertion at nt 44,827 of the Smith MCMV BAC, was attenuated in replication both in tis...

journal_title：Journal of medical virology

authors： Baluchova K,Kirby M,Ahasan MM,Sweet C

更新日期：2008-07-01 00:00:00

abstract：:Genotype 1F was likely localized geographically to China as it has not been reported elsewhere. In this study, whole genome sequences of two rubella 1F virus isolates were completed. Both viruses contained 9,761 nt with a single nucleotide deletion in the intergenic region, compared to the NCBI rubella reference seque...

journal_title：Journal of medical virology

authors： Zhu Z,Chen MH,Abernathy E,Zhou S,Wang C,Icenogle J,Xu W

更新日期：2014-12-01 00:00:00

abstract：:The prevalence of delta agent among 120 Chinese patients with HBsAg-positive chronic active and hepatocellular carcinoma from Taiwan and Los Angeles were studied by serological assay for antibody to delta antigen and immunoperoxidase staining for delta antigen in the liver biopsies. Of 120 patients, only four with chr...

journal_title：Journal of medical virology

authors： Govindarajan S,Lee SD,Tong MJ,Tsai YT,Lo KJ

更新日期：1984-01-01 00:00:00

abstract：:Comparison of RT-PCR assays established in house at various places revealed that laboratories could differ in sensitivity by as much as 1,000-fold in terms of the ability to detect measles virus sequences in clinical samples. The study indicates that PCR findings, positive or negative, are questionable if they are not...

journal_title：Journal of medical virology

authors： Afzal MA,Osterhaus AD,Cosby SL,Jin L,Beeler J,Takeuchi K,Kawashima H

更新日期：2003-05-01 00:00:00

abstract：:Total RNA from normal adult woodchucks was analyzed using membrane arrays containing human cDNA clones, and the gene expression patterns were compared to human liver. Various hybridization and wash conditions were examined. In both the woodchuck and human livers, 352 genes were identified as highly expressed (Z-scores...

journal_title：Journal of medical virology

authors： Rinaudo JA,Gerin JL

更新日期：2004-10-01 00:00:00

abstract：:Ultra violet (UV) light-inactivated measles virus was used for the lymphocyte proliferation assay, where it caused consistently adult human peripheral blood monolymphocytes (PBML) proliferation which was not dependent on the measles virus complement fixation titre in the donor's sera. When the cord blood lymphocytes f...

journal_title：Journal of medical virology

authors： Tu R

更新日期：1995-06-01 00:00:00

abstract：:The 30-base pair (bp) deletion of the cytoplasmic carboxy-terminal domain of the latent membrane protein 1 (LMP-1) gene was analyzed in 37 frozen tissues from patients with Epstein-Barr virus (EBV)-related gastric cancer and 18 throat washings from healthy adults in southern Japan. The 30-bp deletion was identified in...

journal_title：Journal of medical virology

authors： Mori S,Itoh T,Tokunaga M,Eizuru Y

更新日期：1999-02-01 00:00:00

abstract：:The evaluation of new therapeutic resources against coronavirus disease 2019 (COVID-19) represents a priority in clinical research considering the minimal options currently available. To evaluate the adjuvant use of systemic oxygen-ozone administration in the early control of disease progression in patients with COVID...

journal_title：Journal of medical virology

authors： Araimo F,Imperiale C,Tordiglione P,Ceccarelli G,Borrazzo C,Alessandri F,Santinelli L,Innocenti GP,Pinacchio C,Mauro V,Recchia GE,Zancla S,Calò A,Poscia R,Ruberto F,d'Ettorre G,Bilotta F,Mastroianni C,Pugliese F

更新日期：2020-10-28 00:00:00

abstract：:Human parechoviruses (HPeV) are associated with central nervous system (CNS) infections and sepsis-like illnesses. However, data from China are not available. The aim of this study was to determine the prevalence, age, and seasonal distributions and genotypes of HPeV infections in children with CNS related disease in ...

journal_title：Journal of medical virology

authors： Zhong H,Lin Y,Su L,Cao L,Xu M,Xu J

更新日期：2013-02-01 00:00:00

abstract：:Chikungunya fever is a viral disease transmitted to humans by the bite of infected mosquitoes. The disease is characterized by fever, headache, rash, severe joint, and muscle pain. To evaluate the disease burden in the population and the effectiveness of public health measures, periodic seroprevalence surveys are esse...

journal_title：Journal of medical virology

authors： Shilpa C,Kavitha K,Sudheesh N,Sabeena S,Prasad V,Hindol M,Arunkumar G

更新日期：2020-01-01 00:00:00

abstract：:Rapid diagnosis of human herpesvirus primary infections or reactivations is facilitated by quantitative PCRs. Quantitative PCR assays with a standard thermal cycling profile permitting simultaneous detection of herpes simplex virus (HSV), varicella zoster virus (VZV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), a...

journal_title：Journal of medical virology

authors： Engelmann I,Petzold DR,Kosinska A,Hepkema BG,Schulz TF,Heim A

更新日期：2008-03-01 00:00:00

abstract：:Paired sera, saliva and cervicovaginal secretions from 17 HTLV-I-infected women (19-75 yr) were tested for total IgA and IgG, for IgA and IgG to the immunodominant region gp46/175-Pro-199, for serum IgG to the neutralizing domains gp46/ 190-Pro-199 and gp46/190-Ser-199, or for tax-rex proviral HTLV-DNA. Serum antibodi...

journal_title：Journal of medical virology

authors： Bélec L,Georges-Courbot MC,Georges A,Mohamed AS,Londos-Gagliardi D,Hallouin MC,Hocini H,Guillemain B

更新日期：1996-09-01 00:00:00

abstract：:In this meta-analysis, we evaluated the diagnostic role of Epstein-Barr virus deoxyribonucleic acid detection and quantitation in the serum of pediatric and young adult patients with infectious mononucleosis. The primary outcome of this meta-analysis was the sensitivity and specificity of Epstein-Barr virus (EBV) deox...

journal_title：Journal of medical virology

authors： Jiang SY,Yang JW,Shao JB,Liao XL,Lu ZH,Jiang H

更新日期：2016-05-01 00:00:00

abstract：:The epidemiology of HTLV-I infection in female prostitutes was studied in a survey of 395 prostitutes from Callao, Peru (the port city of Lima), 72 prostitutes from Iquitos, Peru (another port city on the Amazon River), and 510 prenatal clinic patients from Lima. Prostitutes reported a mean of 8.8 years (range, 1-39 y...

journal_title：Journal of medical virology

authors： Wignall FS,Hyams KC,Phillips IA,Escamilla J,Tejada A,Li O,Lopez F,Chauca G,Sanchez S,Roberts CR

更新日期：1992-09-01 00:00:00

abstract：:Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG dinucleotides within the context of certain flanking bases (CpG motifs) have been shown to induce potent innate and adaptive immune responses. Vaginal delivery of CpG ODN alone protects mice from vaginal herpes simplex virus type-2 (HSV-2) challenge. He...

journal_title：Journal of medical virology

authors： Sajic D,Ashkar AA,Patrick AJ,McCluskie MJ,Davis HL,Levine KL,Holl R,Rosenthal KL

更新日期：2003-12-01 00:00:00

abstract：:A single rotavirus strain causing asymptomatic infections as well as severe gastrointestinal disease has been described in the neonatal nurseries of the Christian Medical College, Vellore. In this study, quantitative real-time RT-PCR was used to determine the association of viral load with the presence of gastrointest...

journal_title：Journal of medical virology

authors： Ramani S,Sankaran P,Arumugam R,Sarkar R,Banerjee I,Mohanty I,Jana AK,Kuruvilla KA,Kang G

更新日期：2010-10-01 00:00:00

abstract：:We developed approaches using antisense RNA to inhibit hepatitis C virus (HCV) RNA translation and HCV core protein expression. An HCV genotype 1b cDNA comprising nt 1-1321 or a fusion construct consisting of HCV (nt 1-584) and luciferase cDNAs were inserted downstream of T7 and CMV promoter sequences and used to gene...

journal_title：Journal of medical virology

authors： Wakita T,Moradpour D,Tokushihge K,Wands JR

更新日期：1999-03-01 00:00:00

abstract：:Rotavirus is the most common etiological cause of acute viral gastroenteritis in infants and young children worldwide, yet its role in the adult population is less well understood. We have recently identified rotavirus as the causative agent of severe diarrhea in adults, specifically in two gastroenteritis outbreaks i...

journal_title：Journal of medical virology

authors： Feeney SA,Mitchell SJ,Mitchell F,Wyatt DE,Fairley D,McCaughey C,Coyle PV,O'Neill HJ

更新日期：2006-08-01 00:00:00

abstract：:Thirty susceptible rhesus monkeys were inoculated with cell-free varicella-zoster virus strain OKA or strain KMcC. Both wild and attenuated strains were used. No clinical signs characteristic of human varicella were seen in any of the animals. Virus was not isolated from throat swabs, blood, or cerebrospinal fluid. An...

journal_title：Journal of medical virology

authors： Asano Y,Albrecht P,Behr DE,Neff BJ,Vickers JH,Rastogi SC

更新日期：1984-01-01 00:00:00

abstract：:Currently, data examining nationally representative prevalence and trends of HBV or HCV among specific subgroups of pregnant women in the US are unavailable. We conducted a cross-sectional analysis of hospitalizations for liveborn singleton deliveries from 1998 to 2011 using data from the Nationwide Inpatient Sample. ...

journal_title：Journal of medical virology

authors： Salemi JL,Spooner KK,Mejia de Grubb MC,Aggarwal A,Matas JL,Salihu HM

更新日期：2017-06-01 00:00:00

abstract：:Self-limited involvement of the central nervous system (CNS) is a relatively common complication of primary infection with human herpesvirus six (HHV-6) in normal children. We describe an HIV-infected infant who developed fulminant encephalitis as a complication of HHV-6 infection. Immunohistochemical staining of CNS ...

journal_title：Journal of medical virology

authors： Knox KK,Harrington DP,Carrigan DR

更新日期：1995-03-01 00:00:00

abstract：:A viral surveillance system in Nashville detected an outbreak of influenza B that occurred between January and March 1986. Paired sera from 32 individuals with culture-documented influenza B illness were tested using three serologic assays. Enzyme-linked immunosorbent assay (ELISA) using purified hemagglutinin-neurami...

journal_title：Journal of medical virology

authors： King JC Jr,Haugh CJ,Dupont WD,Thompson JM,Wright PF,Edwards KM

更新日期：1988-07-01 00:00:00

abstract：:The prevalence of coinfection and superinfection with the delta agent was studied in 2,645 hepatitis B surface antigen (HBsAg)-positive subjects from six countries and nine islands in the Western Pacific region. The study group comprised 262 patients with acute hepatitis B and 2,383 chronic carriers of HBsAg, of whom ...

journal_title：Journal of medical virology

authors： Dimitrakakis M,Crowe S,Gust I

更新日期：1986-04-01 00:00:00