Abstract：
:A viral surveillance system in Nashville detected an outbreak of influenza B that occurred between January and March 1986. Paired sera from 32 individuals with culture-documented influenza B illness were tested using three serologic assays. Enzyme-linked immunosorbent assay (ELISA) using purified hemagglutinin-neuraminidase and plaque neutralization detected a seroresponse in 69% and 66% of these individuals, respectively. These assays were superior to hemagglutination inhibition, which detected a 41% seroresponse. ELISA was perferred because of cost and ease of performance. A group of 286 individuals, aged 1-65 years, was studied more extensively including serologic assessment before and after the influenza B outbreak. Historical information and viral throat cultures were obtained from those with influenza-like illness during the epidemic. An influenza B infection rate (seroresponse and/or positive culture) of 31% and illness rate (infection with flu-like symptoms during the epidemic period) of 13% was demonstrated using these methods. Pre-epidemic mean serum ELISA IgG titers were lower in those with, versus those without, evidence of subsequent influenza B illness (1,541 vs. 4,311, P = .0026). Children less than or equal to 15 years of age were infected more frequently than adults (44% vs. 28%, P = .04). Fever greater than or equal to 101 degrees F was reported more frequently with influenza B than non-B illness (43% vs. 18%, P = .03). These data are useful in preparing for future epidemiologic studies of influenza B and demonstrate the value of and need for standardization of ELISA as a serologic assay for influenza B.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
King JC Jr,Haugh CJ,Dupont WD,Thompson JM,Wright PF,Edwards KMdoi
10.1002/jmv.1890250313subject
Has Abstractpub_date
1988-07-01 00:00:00pages
361-8issue
3eissn
0146-6615issn
1096-9071journal_volume
25pub_type
临床试验,杂志文章abstract：:Although hepatitis E virus (HEV) infection is a zoonosis, there is, currently, no standardized assay for quantitatively measuring anti-HEV antibody levels in HEV animal reservoirs. In this study, anti-HEV antibody positive serum from a rabbit (RS26) was calibrated by dose-response parallel line assay using the World H...
journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.24651
更新日期：2017-03-01 00:00:00
abstract：:Hantaviruses is an emerging infectious disease. Although HCPS has been reported in several regions of Brazil, more cases of HCPS have recently been reported in Minas Gerais than in any other state. In 2009, we analyzed 27 samples presenting antibodies against hantaviruses. These samples originated from 688 symptomatic...
journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.24118
更新日期：2015-05-01 00:00:00
abstract：:The multiplication of HSV-1 and HSV-2 strains in the heart and the corresponding dorsal root ganglia (DRG) was examined in experimentally infected mice. Infectious HSV-1 was recovered from the heart between the second and fourth day after inoculation and 3 days later from the DRG. Both the heart and DRG yielded infect...
journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.1890070211
更新日期：1981-01-01 00:00:00
abstract：:The effect of protamine, atropine, selenocystamine, taxifolin, and catechin on the infectivity and antigenicity of the cell culture-adapted hepatitis A virus (HAV) strain CF 53 was studied. The toxicity on uninfected PLC/PRF/5 cells was examined for each antiviral compound by morphological and biochemical methods, in ...
journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.1890220108
更新日期：1987-05-01 00:00:00
abstract：:A small percentage of renal patients become infected with the BK polyomavirus (BKV), a pathogenic virus that causes BKV-associated nephropathy (BKVN), after kidney transplantation. This study presents a simple, rapid, high-throughput method for BKV genotyping using high-resolution melt analysis (HRMA). Using this nove...
journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.22239
更新日期：2011-12-01 00:00:00
abstract：:In the nine years since the Global Advisory Group of the Expanded Programme on Immunisation (WHO) set 1997 as the target for integrating hepatitis B vaccination into national immunisation programmes worldwide, 129 countries have included hepatitis B vaccine as part of their routine infant or adolescent immunisation pr...
journal_title：Journal of medical virology
pub_type： 杂志文章,评审
doi：10.1002/jmv.10091
更新日期：2002-07-01 00:00:00
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journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.21306
更新日期：2008-11-01 00:00:00
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journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.1890350107
更新日期：1991-09-01 00:00:00
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journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.21095
更新日期：2008-03-01 00:00:00
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journal_title：Journal of medical virology
pub_type： 信件
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更新日期：2020-11-03 00:00:00
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journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.20830
更新日期：2007-04-01 00:00:00
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journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.23415
更新日期：2013-02-01 00:00:00
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journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.21379
更新日期：2009-02-01 00:00:00
abstract：:Because in situ/filter hybridisation is not sensitive enough and because classical polymerase chain reaction (PCR) protocols are generally not sufficiently reproducible and specific, there is little accurate information on the prevalence of human papillomaviruses (HPV) 16, 18, and 33 infections in women without dyskar...
journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.1890360409
更新日期：1992-04-01 00:00:00
abstract：:Herpes simplex virus (HSV) establishes latency in neurons and recurrent infections in oral mucosa. This prospective study analyzes HSV prevalence in oral mucosal brush samples from men with known human papillomavirus (HPV) status. We hypothesized that HSV-1-infection could facilitate HPV persistence as a cofactor. Thi...
journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.24965
更新日期：2018-03-01 00:00:00
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journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.26013
更新日期：2020-05-15 00:00:00
abstract：:The genotypes and subtypes of 205 HBV isolates collected during 1989-2002 in Estonia and 14 other regions of the former USSR were determined by sequencing and phylogenetic analysis of the S gene. The in Europe prevailing genotypes, A and D, were also circulating in the whole territory of the former USSR including Esto...
journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.20169
更新日期：2004-10-01 00:00:00
abstract：:Knowledge of the precise timing of SARS-CoV-2 infection may be of clinical and epidemiological relevance. The presence of low-avidity IgGs has conventionally been considered an indicator of recent infection. Here, we carried out qualitative assessment of SARS-CoV-2-specific antibody avidity using an urea (6M) dissocia...
journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.26344
更新日期：2021-02-01 00:00:00
abstract：:A total of 82 samples from patients with cervical cancer (Group 1) and 50 samples from patients with other genital diseases (Group 2) were collected in Gansu, China. All 132 samples were tested for HPV DNA with a typing kit that can detect 21 types of HPV, and also tested for neutralizing antibodies against HPV-16, -1...
journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.21435
更新日期：2009-04-01 00:00:00
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journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.26467
更新日期：2021-02-01 00:00:00
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journal_title：Journal of medical virology
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
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journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.1890020102
更新日期：1978-01-01 00:00:00
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journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/(sici)1096-9071(199708)52:4<413::aid-jmv12
更新日期：1997-08-01 00:00:00
abstract：:BKPyV replication is a risk factor for the development of polyomavirus-associated nephropathy in kidney transplant recipients. Here, the case of a 42 years old Caucasian patient is described who developed a kidney allograft failure because of uncontrolled BKPyV replication 7 months after transplant despite a strong re...
journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.25458
更新日期：2019-09-01 00:00:00
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journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.25694
更新日期：2020-08-01 00:00:00
abstract：:Although there is a low prevalence rate (around 1% of the population) of infection with hepatitis B virus (HBV) and hepatitis C virus (HCV) in Chile, little is known about the diversity and molecular characteristics of the circulating viruses. In the present study, 40 HBV and 57 HCV samples from Santiago City, Chile, ...
journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.21607
更新日期：2009-11-01 00:00:00
abstract：:A multiplex polymerase chain reaction (PCR) assay that is capable of detecting and typing six serotypes of respiratory adenovirus (Ad) was developed, using multiple sets of type-specific primers. The detection of each different serotype depended on distinguishing different numbers and sizes of amplification products o...
journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.2174
更新日期：2002-04-01 00:00:00
abstract：:A rapid technique for the detection of hepatitis C virus (HCV) RNA in liver section using nonisotopic in situ hybridization was described. Only 3 of the 10 patients seropositive for antibody to HCV and HCV RNA had detectable HCV RNA in the hepatocytes (1%, 2%, and 15% of cells positive). No specific signal was detecte...
journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.1890420313
更新日期：1994-03-01 00:00:00
abstract：:Although a T-cell response in human cytomegalovirus (HCMV)-immune individuals exists against the most abundantly expressed protein pp65 of the virus matrix, less is known about the determinants that evoke this response. The aim of the study was to identify regions within HCMV pp65 (ppUL83) that contain sequences for t...
journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/(sici)1096-9071(199705)52:1<68::aid-jmv11>
更新日期：1997-05-01 00:00:00
abstract：:A combined hepatitis A and B vaccine is available since 1996. Two separate open-label primary studies evaluated the immunogenicity and safety of this hepatitis A and B vaccine (720 EI.U of HAV and 20 µg of HBsAg) in 306 healthy subjects aged 17-43 years who received three doses of the vaccine following a 0, 1, and 6 m...
journal_title：Journal of medical virology
pub_type： 杂志文章
doi：10.1002/jmv.22264
更新日期：2012-01-01 00:00:00
