Detection of hepatitis C virus RNA genome in liver tissue by nonisotopic in situ hybridization.

abstract：:Heterogeneity of hepatitis C viral (HCV) genomes of several isolates from different countries has been reported, but there is little information on HCV isolates for the Federal Republic of Germany. Therefore, the nucleotide (nt) and deduced amino acid (aa) sequences of interesting parts of the viral genome derived fro...

journal_title：Journal of medical virology

authors： Müller HM,Pfaff E,Goeser T,Theilmann L

更新日期：1993-08-01 00:00:00

abstract：:Virological studies were carried out on 3 to 36-month-old patients admitted to the Children's Hospital of the University of Modena with febrile syndrome from September 1990 to February 1991. Virological tests were carried out for human herpesvirus-6 (HHV-6), Epstein-Barr virus (EBV), cytomegalovirus (CMV), herpes simp...

journal_title：Journal of medical virology

authors： Portolani M,Cermelli C,Moroni A,Bertolani MF,Di Luca D,Cassai E,Sabbatini AM

更新日期：1993-02-01 00:00:00

abstract：:To elucidate the role of host immune status in the evolution and complexity of hepatitis C virus (HCV) quasispecies, three chronic HCV-infected patients who underwent bone marrow transplantation (BMT) were studied. The three transplanted patients' sera were sampled at pre-BMT, 3 months after BMT, and 12 months after B...

journal_title：Journal of medical virology

authors： Ni YH,Chang MH,Chen PJ,Hsu HY,Lu TW,Lin KH,Lin DT

更新日期：1999-06-01 00:00:00

abstract：:The seroprevalences of hepatitis B virus (HBV) and hepatitis C virus (HCV) markers were evaluated in a random sample of 803 children attending school in Ashanti-Akim North district in Ghana in order to gain a better understanding of transmission patterns of these viruses, particularly horizontal transmission of HBV. T...

journal_title：Journal of medical virology

authors： Martinson FE,Weigle KA,Mushahwar IK,Weber DJ,Royce R,Lemon SM

更新日期：1996-03-01 00:00:00

abstract：:The presence of the E2 region of HPV 16 was determined by the polymerase chain reaction in biopsy samples with different histopathological diagnoses. The absence of the E2 gene was observed in 17 of 30 cases examined. The E2 deletions were not confined exclusively to invasive carcinomas or to integrated viral forms. I...

journal_title：Journal of medical virology

authors： Krajinovic M,Lazic J,Stanimirovic B,Diklic V,Savic A

更新日期：1993-09-01 00:00:00

abstract：:Recent studies have suggested a pathogenic role of human parvovirus B19 (B19) in the development of acute fulminant liver failure in children. The hypothesis was based on the detection of B19 DNA in 8 of 10 explanted livers of children requiring liver transplantation. In the present study, explanted livers from 43 adu...

journal_title：Journal of medical virology

authors： Eis-Hübinger AM,Reber U,Abdul-Nour T,Glatzel U,Lauschke H,Pütz U

更新日期：2001-10-01 00:00:00

abstract：:Hepatitis C virus (HCV) virions have been shown to be bound to antibodies in patients with chronic HCV infection. The sera from patients infected with genotype 1b HCV contained more antibody-free virions than those from patients with genotype 2a/2b HCV. When compared at the same levels of serum HCV RNA, free virion ti...

journal_title：Journal of medical virology

authors： Kimura Y,Hayashida K,Ishibashi H,Niho Y,Yanagi Y

更新日期：2000-05-01 00:00:00

abstract：:HIV-1 drug resistance mutations (DRMs) and substitutions were assessed after the failure of the first line non-nucleoside reverse transcriptase inhibitors (NNRTIs) + 2 nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) treatment regimens (efavirenz [EFV] + lamivudine[3TC] + zidovudine [ZDV] vs. EFV + 3TC +...

journal_title：Journal of medical virology

authors： Avi R,Pauskar M,Karki T,Kallas E,Jõgeda EL,Margus T,Huik K,Lutsar I

更新日期：2016-03-01 00:00:00

abstract：:Immune-specific IFN (IFN) is produced by the peripheral blood mononuclear leukocytes (PBML) of greater than 95% of HSV-seropositive humans with infrequent recurrences of herpes labialis [Green, Yeh, and Overall, 1981]. However, herpes virus-induced immune-specific IFN was produced by PBML from only 33 of 48 (68.8%) pe...

journal_title：Journal of medical virology

authors： Green JA,Weiss PN,Yeh TJ,Spruance SL

更新日期：1985-07-01 00:00:00

abstract：:A novel coronavirus associated with acute respiratory disease (named SARS-CoV-2) is recently identified in Wuhan city, China, spread rapidly worldwide. Early identification of this novel coronavirus by molecular tools is critical for surveillance and control of the epidemic outbreak. We aimed to establish a simple met...

journal_title：Journal of medical virology

authors： Son HA,Hang DTT,Thuan ND,Quyen LTB,Thuong LTH,Nga VT,Quang LB,Hung TT,Son NT,Linh NT,Nam LV,Van Ba N,Tien TV,Quyet D,Van Luong H,Su HX

更新日期：2020-11-01 00:00:00

abstract：:Human metapneumovirus (hMPV) is considered an important cause of acute respiratory infections. hMPV can cause morbidity in hematopoietic stem cell transplant recipients and recent research has demonstrated that it is an important virus in patients admitted to hospital with respiratory infections and suspected of havin...

journal_title：Journal of medical virology

authors： Souza JS,Watanabe A,Carraro E,Granato C,Bellei N

更新日期：2013-03-01 00:00:00

abstract：:Amphotropic murine leukemia virus (MLV) replicates in cells from various mammalian species including humans and is a potential contaminant in MLV vector preparations for human gene transfer studies. In general, MLV replication depends on the expression of viral genes under the control of 75 bp enhancer elements in the...

journal_title：Journal of medical virology

authors： Reuss FU,Berdel B,Heber R,Bantel-Schaal U

更新日期：2002-10-01 00:00:00

abstract：:There is an obvious concern globally regarding the fact about the emerging coronavirus 2019 novel coronavirus (2019-nCoV) as a worldwide public health threat. As the outbreak of COVID-19 causes by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) progresses within China and beyond, rapidly available epi...

journal_title：Journal of medical virology

authors： Dey SK,Rahman MM,Siddiqi UR,Howlader A

更新日期：2020-06-01 00:00:00

abstract：:This study describes two measles outbreaks--one in Cape Town, South Africa in November 2002, and the other in Luanda, Angola in March 2003. The outbreaks were notable because they were caused by closely related genotype B2 viruses. This genotype was first described in an outbreak in Libreville, Gabon in the 1980s and ...

journal_title：Journal of medical virology

authors： Smit SB,Hardie D,Tiemessen CT

更新日期：2005-12-01 00:00:00

abstract：:A sensitive and specific nonradioactive in situ hybridization method capable of detecting single-copy integrated hepatitis B virus (HBV) DNA sequences in hepatocellular carcinoma (HCC) cell lines was developed. In situ hybridization of biotinylated HBV (adr, adw) DNA probes with nine different human HCC cell lines wer...

journal_title：Journal of medical virology

authors： Tay N,Chan SH,Ren EC

更新日期：1990-04-01 00:00:00

abstract：:A highly sensitive one-step real-time RT-PCR method using a minor-groove-binding (MGB) probe was developed for detection and quantitation of severe febrile with thrombocytopenia syndrome virus (SFTSV). The assay could discriminate SFTSV infection from other related viral diseases in human with a minimum detection limi...

journal_title：Journal of medical virology

authors： Li Z,Cui L,Zhou M,Qi X,Bao C,Hu J,Shan J,Wu B,Wang S,Guo X,Jiao Y,Tang F,Wang H

更新日期：2013-02-01 00:00:00

abstract：:A total of 402 fecal specimens collected during July 2003-June 2004 from infants and children with acute gastroenteritis, encompassing five localities (Maizuru, Tokyo, Sapporo, Saga, and Osaka) of Japan, were tested for the presence of norovirus by RT-PCR. It was found that 58 (14.4%) fecal specimens were positive for...

journal_title：Journal of medical virology

authors： Phan TG,Kuroiwa T,Kaneshi K,Ueda Y,Nakaya S,Nishimura S,Yamamoto A,Sugita K,Nishimura T,Yagyu F,Okitsu S,Müller WE,Maneekarn N,Ushijima H

更新日期：2006-07-01 00:00:00

abstract：:A cohort of 127 nursing home residents aged 60-98 years were vaccinated during the winter of 1985-86 with the A-Chile 1/83 (C), A-Philippines 2/82 (P), and B-USSR (B) commercial influenza vaccines. Before vaccination 40%, 23%, and 69% were susceptible to influenza Ac, Ap, and B, respectively [hemagglutinin inhibition ...

journal_title：Journal of medical virology

authors： Keren G,Segev S,Morag A,Zakay-Rones Z,Barzilai A,Rubinstein E

更新日期：1988-05-01 00:00:00

abstract：:Hepatitis A virus infections have been reported recently among hemophilic patients in Italy and Germany, leading to speculation that infectious hepatitis A virus (HAV) might have been present in some factor VIII concentrates. In both cases, the implicated factor concentrates had been treated by a solvent/detergent met...

journal_title：Journal of medical virology

authors： Murphy P,Nowak T,Lemon SM,Hilfenhaus J

更新日期：1993-09-01 00:00:00

abstract：:An attempt was made to identify factors influencing the cumulative probability of an increased alanine aminotransferase (ALT) level and hepatocarcinogenesis in hepatitis C patients with a normal ALT level initially. A total of 398 consecutive patients with a normal ALT level initially for 6 months or more and follow-u...

journal_title：Journal of medical virology

authors： Kumada T,Toyoda H,Kiriyama S,Sone Y,Tanikawa M,Hisanaga Y,Kanamori A,Atsumi H,Takagi M,Nakano S,Arakawa T,Fujimori M

更新日期：2009-03-01 00:00:00

abstract：:Human herpesvirus 6 (HHV-6) and human immunodeficiency virus type 1 (HIV-1) may interact during transplacental transmission of HIV-1. The placental syncytiotrophoblast layer serves as the first line of defense of the fetus against viruses. Patterns of replication of HHV-6 variant A (HHV-6A) and HIV-1 were analyzed in ...

journal_title：Journal of medical virology

authors： Csoma E,Bácsi A,Liu X,Szabó J,Ebbesen P,Beck Z,Kónya J,Andirkó I,Nagy E,Tóth FD

更新日期：2002-05-01 00:00:00

abstract：:Human herpesvirus 6 (HHV6) is a beta-herpesvirus capable of infecting several cell types from different origins. HHV6 is the etiological agent of exantem subitum and has been associated with several diseases, all characterized by an inflammatory response triggered by chemokines. We show that strain U1102 of HHV6 is ab...

journal_title：Journal of medical virology

authors： Caruso A,Favilli F,Rotola A,Comar M,Horejsh D,Alessandri G,Grassi M,Di Luca D,Fiorentini S

更新日期：2003-07-01 00:00:00

abstract：:Herpes simplex virus (HSV)-specific IgG and IgA antibody response in patients with HSV infection and in healthy adults was studied by the immunoperoxidase antibody-membrane antigen (IPAMA) technique. In all HSV infections in which specific IgM antibodies were detected by enzyme-linked immunosorbent assay (ELISA), a si...

journal_title：Journal of medical virology

authors： Hadar T,Sarov I

更新日期：1984-01-01 00:00:00

abstract：:We read with great interest the recent issue,1 which raised the concern about the co-circulation of dengue during the COVID-19 pandemic. This article is protected by copyright. All rights reserved. ...

journal_title：Journal of medical virology

authors： Lin SF,Lai CC,Chao CM,Tang HJ

更新日期：2020-11-03 00:00:00

abstract：:The live varicella vaccine has been recommended for use in immunocompromised subjects and in adults who are susceptible to chickenpox. However, we do not know how humoral and cell-mediated immune responses induced after vaccination differed from those obtained after natural infection. To answer this, 45 previously inf...

journal_title：Journal of medical virology

authors： Ndumbe PM,Cradock-Watson J,Levinsky RJ

更新日期：1988-06-01 00:00:00

abstract：:Rabbit antibodies produced by immunization with complete hepatitis A virions (HAV) recognized all the viral structural proteins and neutralized HAV infectivity in cell culture. Rabbit antibodies to chromatographically purified individual viral proteins and to synthetic peptides representing epitopes on the structural ...

journal_title：Journal of medical virology

authors： Gauss-Müller V,Deinhardt F

更新日期：1988-02-01 00:00:00

abstract：:HIV is among the most generically variable of human pathogens. A comprehensive and detailed description of HIV strains in the pandemic is an important foundation for diagnosis, treatment, and prevention. The current sequence database for HIV includes almost 800 complete genome sequences, documenting HIV-1 groups M, O,...

journal_title：Journal of medical virology

authors： McCutchan FE

更新日期：2006-01-01 00:00:00

abstract：:A method for the absorption of false radioimmunoassay (RIA) IgM titres against herpes simplex virus (HSV) and cytomegalovirus (CMV) is presented. The serum specimens were absorbed by a mixture of protein A-Sepharose and protein A-Sepharose saturated with normal human gamma globulin (PAS/IgG). The detection of rheumato...

journal_title：Journal of medical virology

authors： Torfason EG,Diderholm H

更新日期：1982-01-01 00:00:00

abstract：:A line of hepatitis C virus (HCV) transgenic mice was established previously that was mediated by Cre/loxP system using HCV cDNA, including core, E1, E2 and NS2 genes. Intravenous infection of a recombinant adenovirus that expresses Cre DNA recombinase (AxCANCre) induced HCV structural protein expression in the liver ...

journal_title：Journal of medical virology

authors： Wakita T,Katsume A,Kato J,Taya C,Yonekawa H,Kanegae Y,Saito I,Hayashi Y,Koike M,Miyamoto M,Hiasa Y,Kohara M

更新日期：2000-11-01 00:00:00

abstract：:Despite a significant decrease in acute hepatitis A in the last 2 decades in Italy, outbreaks were observed occurring mostly in southern Italy. In this study, Bayesian phylogenetic analysis was used to analyze the origin of these epidemics. With this aim, 5 different data sets of hepatitis A virus sequences were built...

journal_title：Journal of medical virology

authors： Cella E,Riva E,Angeletti S,Fogolari M,Blasi A,Scolamacchia V,Spoto S,Bazzardi R,Lai A,Sagnelli C,Sagnelli E,Ciccozzi M

更新日期：2018-09-01 00:00:00