Human cytomegalovirus as a direct pathogen: correlation of multiorgan involvement and cell distribution with clinical and pathological findings in a case of congenital inclusion disease.

abstract：:Human metapneumovirus, with two known genotypes named A and B, is associated with mild respiratory symptoms to severe LRTI in children, high-risk adults and the elderly. Rapid and reliable methods of hMPV detection in clinical samples are essential to implement appropriate care, to better understand the pathology of h...

journal_title：Journal of medical virology

authors： Manoha C,Bour JB,Pitoiset C,Darniot M,Aho S,Pothier P

更新日期：2008-01-01 00:00:00

abstract：:Stool specimens from 334 infants and young children hospitalized with diarrhea in the General Hospital, Kuala Lumpur, Malaysia between August and November, 1987 were analyzed for the presence of rotavirus double-stranded (ds) RNA by polyacrylamide gel electrophoresis. Of the 334 specimens analyzed, 32 (9.6%) were posi...

journal_title：Journal of medical virology

authors： Rasool NB,Hamzah M,Jegathesan M,Wong YH,Qian Y,Green KY

更新日期：1994-07-01 00:00:00

abstract：:The prevalence of picobirnaviruses (PBVs) in human stools was investigated by polyacrylamide gel electrophoresis (PAGE) analysis of 832 faecal specimens collected between 1982 and 1993 from patients in various clinical groups. Similar prevalences (9-13%) were detected in patients with or without gastroenteritis and th...

journal_title：Journal of medical virology

authors： Gallimore CI,Appleton H,Lewis D,Green J,Brown DW

更新日期：1995-02-01 00:00:00

abstract：:In order to determine whether peripheral blood mononuclear cells (PBMC) contain proviral DNA or double-stranded replicative forms of TT virus (TTV) and to define which cell subset harbors TTV, we analyzed 126 PBMC DNA samples by PCR, using the NG059/NG061/NG063 and the T801/T935 primer sets. TTV sequences were detecte...

journal_title：Journal of medical virology

authors： Yu Q,Shiramizu B,Nerurkar VR,Hu N,Shikuma CM,Melish ME,Cascio K,Imrie A,Lu Y,Yanagihara R

更新日期：2002-02-01 00:00:00

abstract：:We developed an immunoperoxidase staining test to detect structural antigens of BK virus (BKV) in Vero cell cultures. This test was used to examine the neutralizing activity of human and immunized animal sera. It was shown that sera positive for BKV antibodies measured by hemagglutination inhibition test and enzyme-li...

journal_title：Journal of medical virology

authors： Flaegstad T,Traavik T,Christie KE,Joergensen J

更新日期：1986-07-01 00:00:00

abstract：:As with hepatitis B vaccines, the recently developed hepatitis A vaccine is suitable not only for individual protection, but also for public health control measures. For introduction into routine immunisation programmes, however, hepatitis A vaccine should preferably be combined with other already established vaccines...

journal_title：Journal of medical virology

authors： Ambrosch F,Wiedermann G,André FE,Delem A,Gregor H,Hofmann H,D'Hondt E,Kundi M,Wynen J,Kunz C

更新日期：1994-12-01 00:00:00

abstract：:Varicella-zoster virus (VZV)-specific cell-mediated immunity (CMI) is critical for preventing and controlling the onset of herpes zoster (HZ). To assess VZV CMI, an interferon-γ (IFN-γ) enzyme-linked immunosorbent assay (ELISA) was validated by examining the influence of VZV-specific antigen content, incubation time, ...

journal_title：Journal of medical virology

authors： Yang P,Chen Z,Zhang J,Li W,Zhu C,Qiu P,Quan Y,Cui X,Yuan L,Jiang C

更新日期：2019-05-01 00:00:00

abstract：:To determine the influence of ageing per se as well as of priming histories on the antibody response to influenza vaccination, haemagglutination inhibition (HI), ELISA IgG, IgA, IgM and neutralizing antibody titres were studied in 43 healthy young subjects (mean age 23 years) and 55 healthy elderly people (mean age 79...

journal_title：Journal of medical virology

authors： Remarque EJ,de Bruijn IA,Boersma WJ,Masurel N,Ligthart GJ

更新日期：1998-05-01 00:00:00

abstract：:Rotavirus A (RVA) is the leading cause of acute viral gastroenteritis in children under 5 years of age worldwide. G9P[8] is a common RVA genotype that has been persistently prevalent in Jiangsu, China. To determine the genetic diversity of G9P[8] RVAs, 7 representative G9P[8] strains collected from Suzhou Children's H...

journal_title：Journal of medical virology

authors： Xu C,Fu J,Ai J,Zhang J,Liu C,Huo X,Bao C,Zhu Y

更新日期：2018-09-01 00:00:00

abstract：:Critical cases of coronavirus disease 2019 (COVID-19) are associated with a high risk of mortality. It remains unclear why patients with the same critical condition have different outcomes. We aimed to explore relevant factors that may affect the prognosis of critical COVID-19 patients. Six critical COVID-19 inpatient...

journal_title：Journal of medical virology

authors： Wei LL,Wang WJ,Chen DX,Xu B

更新日期：2020-11-01 00:00:00

abstract：:Amphotropic murine leukemia virus (MLV) replicates in cells from various mammalian species including humans and is a potential contaminant in MLV vector preparations for human gene transfer studies. In general, MLV replication depends on the expression of viral genes under the control of 75 bp enhancer elements in the...

journal_title：Journal of medical virology

authors： Reuss FU,Berdel B,Heber R,Bantel-Schaal U

更新日期：2002-10-01 00:00:00

abstract：:The resurgence of Chikungunya virus (CHIKV) in the form of unprecedented and explosive epidemics in India and the Indian Ocean islands after a gap of 32 years is a major public health concern. Currently, there is no specific therapy available to treat CHIKV infection. In the present study, the in vitro prophylactic an...

journal_title：Journal of medical virology

authors： Khan M,Santhosh SR,Tiwari M,Lakshmana Rao PV,Parida M

更新日期：2010-05-01 00:00:00

abstract：:There are few data describing the comprehensive identification in and influence of newly identified respiratory viruses on asthma exacerbations. Most studies focus on inpatients. In this preliminary study, the point prevalence and the associations of picornavirus species described recently and human bocavirus (HBoV) w...

journal_title：Journal of medical virology

authors： Arden KE,Chang AB,Lambert SB,Nissen MD,Sloots TP,Mackay IM

更新日期：2010-08-01 00:00:00

abstract：:The infectivity titer of a standard stock of the SAR-55 strain of hepatitis E virus (HEV) was determined in cynomolgus macaques (Macaca fascicularis) and the effect of dose on the course of the infection was examined by weekly monitoring of alanine aminotransferase (ALT) and anti-HEV levels. Antibody to HEV (anti-HEV)...

journal_title：Journal of medical virology

authors： Tsarev SA,Tsareva TS,Emerson SU,Yarbough PO,Legters LJ,Moskal T,Purcell RH

更新日期：1994-06-01 00:00:00

abstract：:From the Pacific Republic of Kiribati, 90/130 (69%) of hepatitis B-infected individuals carry antibodies to hepatitis delta virus. The prevalence of delta infection varied between geographically isolated subgroups in the population and delta antibodies were found more frequently in subjects over the age of 10. It is u...

journal_title：Journal of medical virology

authors： Tibbs CJ

更新日期：1989-10-01 00:00:00

abstract：:In early 2008, a sudden increase in oseltamivir (Tamiflu)-resistant influenza A H1N1 viruses was reported from several European countries. This resistant virus has spread globally and accounted for more than 95% of H1N1 viruses isolated in the following influenza season. A continuous close monitoring on the prevalence...

journal_title：Journal of medical virology

authors： Ngai KL,Lam WY,Lee N,Leung TF,Hui DS,Chan PK

更新日期：2010-08-01 00:00:00

abstract：:Hepatitis A virus (HAV) is usually transmitted by an oral-fecal route and is prevalent not only in developing countries but also in developed countries. In the present study, the phylogenetic characterization of the VP1/2A junction region (321 nucleotides) of China HAV isolates was examined. Anti-HAV IgM-positive seru...

journal_title：Journal of medical virology

authors： Cao J,Bi S,Meng Q,Shen L,Zheng H,Zhang Y

更新日期：2011-07-01 00:00:00

abstract：:Chronic hepatitis B virus (HBV) infection is the result of an inadequate immune response towards the virus. Dendritic cells (DCs), as the most efficient professional antigen-presenting cells (APCs), possess the strongest antigen presenting the effect in the body and can stimulate the initial T cell activation and prol...

journal_title：Journal of medical virology

authors： Sun HH,Zhou DF,Zhou JY

更新日期：2016-01-01 00:00:00

abstract：:The objective of the study was to assess the genotypic and phenotypic properties of 18 viral strains from human immunodeficiency virus-1 (HIV-1) positive patients and to identify subtype C isolates for vaccine design strategies. All the isolates were non-syncytium-inducing (NSI) in both the primary and MT-2 cell cultu...

journal_title：Journal of medical virology

authors： Treurnicht FK,Smith TL,Engelbrecht S,Claassen M,Robson BA,Zeier M,van Rensburg EJ

更新日期：2002-10-01 00:00:00

abstract：:Serial determinations of titers of binding antibodies to single stranded DNA were performed over a period of three years in 43 type B hepatitis patients with persisting HBsAg who had either developed chronic hepatitis or were asymptomatic carriers. Patients with histopathological diagnosis of chronic active or chronic...

journal_title：Journal of medical virology

authors： Villarejos VM,Serra J,Visoná KA,Eduarte CE

更新日期：1979-01-01 00:00:00

abstract：:A viral surveillance system in Nashville detected an outbreak of influenza B that occurred between January and March 1986. Paired sera from 32 individuals with culture-documented influenza B illness were tested using three serologic assays. Enzyme-linked immunosorbent assay (ELISA) using purified hemagglutinin-neurami...

journal_title：Journal of medical virology

authors： King JC Jr,Haugh CJ,Dupont WD,Thompson JM,Wright PF,Edwards KM

更新日期：1988-07-01 00:00:00

abstract：:Polyomavirus infection occurring during childhood is followed by a lifelong latency in immunocompetent subjects. The major site of polyomavirus persistence are the uroepithelial cells which leads to oral transmission. It has recently been hypothesized that tonsils could be a possible reservoir. The role of tonsil, ade...

journal_title：Journal of medical virology

authors： Comar M,Zanotta N,Bovenzi M,Campello C

更新日期：2010-07-01 00:00:00

abstract：:Plenty of serologic tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been developed so far, thus documenting the importance of evaluating the relevant features of the immune response to this viral agent. The performance of these assays is currently under investigation. Amongst them, LIAISON®...

journal_title：Journal of medical virology

authors： Criscuolo E,Diotti RA,Strollo M,Rolla S,Ambrosi A,Locatelli M,Burioni R,Mancini N,Clementi M,Clementi N

更新日期：2020-10-16 00:00:00

abstract：:Noroviruses are an important cause of acute gastroenteritis. Increasing data showed that the GII-4 strains are predominant worldwide and new GII-4 variants emerge every 1-2 years causing major epidemics. Surveillance of gastroenteritis in hospitalized children under 5 years of age in China is described. Among 1,110 sp...

journal_title：Journal of medical virology

authors： Jin M,Xie HP,Duan ZJ,Liu N,Zhang Q,Wu BS,Li HY,Cheng WX,Yang SH,Yu JM,Xu ZQ,Cui SX,Zhu L,Tan M,Jiang X,Fang ZY

更新日期：2008-11-01 00:00:00

abstract：:Avidity maturation of IgG antibody responses directed against the structural proteins of rubella virus (E1, E2, and C) as well as whole rubella virus (RV) was assessed at sequential time intervals in 7 individuals following serologically confirmed wild rubella infection. Individual structural proteins were purified fr...

journal_title：Journal of medical virology

authors： Mauracher CA,Mitchell LA,Tingle AJ

更新日期：1992-03-01 00:00:00

abstract：:The nucleotide sequences of the precore/core and X open reading frames (ORFs) of hepatitis B virus (HBV) were studied in four subjects who were serologically negative for anti-hepatitis B core antibody. These subjects were positive for serum hepatitis B surface antigen and were considered to be asymptomatic HBV carrie...

journal_title：Journal of medical virology

authors： Gotoh K,Mima S,Uchida T,Shikata T,Yoshizawa K,Irie M,Mizui M

更新日期：1995-07-01 00:00:00

abstract：:An outbreak of dengue type 2 occurred in North Queensland, Australia, between December 1996 and April 1997. Culture of serum in the Aedes albopictus C6/36 cell line with detection using immunofluorescent staining was compared with a culture-amplified detection system using an immunoperoxidase staining method in a micr...

journal_title：Journal of medical virology

authors： Gleeson F,McBride J,Norton R

更新日期：1999-02-01 00:00:00

abstract：:As the coronavirus disease 2019 pandemic keep tackling global public health systems worldwide. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) genome keeps mutating. In that regard, the recent emergence of the B.1.1.7 lineage in the UK has called the attention of global authorities. One point of concer...

journal_title：Journal of medical virology

authors： Ramírez JD,Muñoz M,Patiño LH,Ballesteros N,Paniz-Mondolfi A

更新日期：2021-01-28 00:00:00

abstract：:In most developing countries, hepatitis B prevention is carried out early in life. In these countries, mobile immunization teams have a limited number of sessions to devote to each rural community; simultaneous administration of multiple antigens is thus normal practice. We compared the immune responses of Senegalese ...

journal_title：Journal of medical virology

authors： Yvonnet B,Coursaget P,Deubel V,Diop-Mar I,Digoutte JP,Chiron JP

更新日期：1986-08-01 00:00:00

abstract：INTRODUCTION:Although the effectiveness of direct-acting antivirals (DAAs) for the treatment of chronic hepatitis C virus (HCV) has been reported in real-world settings, predictive factors of treatment failure are lacking. Therefore, we sought to explore the baseline predictors of treatment response to DAAs. METHODS:T...

journal_title：Journal of medical virology

authors： Ridruejo E,Piñero F,Mendizabal M,Cheinquer H,Wolff FH,Anders M,Reggiardo V,Ameigeiras B,Palazzo A,Alonso C,Schinoni MI,Zuain MGV,Tanno F,Figueroa S,Santos L,Peralta M,Soza A,Vistarini C,Adrover R,Fernández N,Perez

更新日期：2020-08-04 00:00:00