Abstract:
:As the coronavirus disease 2019 pandemic keep tackling global public health systems worldwide. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) genome keeps mutating. In that regard, the recent emergence of the B.1.1.7 lineage in the UK has called the attention of global authorities. One point of concern is that if this lineage can be detected by traditional molecular schemes for SARS-CoV-2 detection. Herein, we showed that this lineage does not affect the Berlin-Charité protocol but can challenge the available commercial kits directed to the Spike (S) gene. All efforts should be made to continue to monitor SARS-CoV-2 genomes for potential variants that can impair diagnostic testing and lead to false negative results.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Ramírez JD,Muñoz M,Patiño LH,Ballesteros N,Paniz-Mondolfi Adoi
10.1002/jmv.26823subject
Has Abstractpub_date
2021-01-28 00:00:00eissn
0146-6615issn
1096-9071pub_type
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