The role of DCs in the immunopathogenesis of chronic HBV infection and the methods of inducing DCs maturation.

abstract：:Cytomegalovirus (CMV) has been implicated in vascular pathologies and may warrant inclusion in cardiovascular predictive algorithms. We addressed this in healthy older adults and renal transplant recipients (RTR) as they retain a high burden of CMV. RTR (n  =  45) stable more than 2 years after transplantation and 58 ...

journal_title：Journal of medical virology

authors： Affandi JS,Lee S,Chih H,Brook E,Waters S,Howson P,Reid CM,Irish A,Price P

更新日期：2020-02-04 00:00:00

abstract：:The effectiveness of a daily continuous infusion of interferon-alpha was evaluated in 12 patients (10 males, 2 females; mean age of 33 years, range 19-62) with biopsy-proven chronic active hepatitis C. Nine million units (MU) of recombinant interferon-alpha 2A (rIFN-alpha 2A) were administered by continuous subcutaneo...

journal_title：Journal of medical virology

authors： Carreño V,Tapia L,Ryff JC,Quiroga JA,Castillo I

更新日期：1992-07-01 00:00:00

abstract：:A method for the absorption of false radioimmunoassay (RIA) IgM titres against herpes simplex virus (HSV) and cytomegalovirus (CMV) is presented. The serum specimens were absorbed by a mixture of protein A-Sepharose and protein A-Sepharose saturated with normal human gamma globulin (PAS/IgG). The detection of rheumato...

journal_title：Journal of medical virology

authors： Torfason EG,Diderholm H

更新日期：1982-01-01 00:00:00

abstract：:Rotavirus infection is associated both in vivo and in vitro with a series of subcellular pathological alterations leading to cell lysis. It has been suggested that these modifications can play a key role in the pathogenesis of rotavirus-associated diarrheal disease. We describe the effects of SA-11 rotavirus infection...

journal_title：Journal of medical virology

authors： Superti F,Ammendolia MG,Tinari A,Bucci B,Giammarioli AM,Rainaldi G,Rivabene R,Donelli G

更新日期：1996-12-01 00:00:00

abstract：:An efficient method for cloning subgenomic fragments of the hepatitis B virus (HBV) was developed, utilizing its abundant single-stranded replicative intermediates. The total genomic DNA obtained from the liver tissue of patients with chronic HBV infection was treated by using the Klenow fragment of E. coli DNA polyme...

journal_title：Journal of medical virology

authors： Kajino K,Ohta Y,Miyamura T,Saito I

更新日期：1991-01-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) is the leading cause of congenital infection and an opportunistic pathogen capable of establishing lifelong latency. In the present study, we aimed to investigate the distribution of glycoprotein B, H, and N in infants of Shanghai and correlate the genotype with active and latent HCMV infe...

journal_title：Journal of medical virology

authors： Dong N,Cao L,Su L,Lu L,Dong Z,Xu M,Xu J

更新日期：2020-06-21 00:00:00

abstract：:This study aimed to examine the application of hepatitis B surface antigen (HBsAg) confirmatory testing when diagnosing hepatitis B infection among young persons in Taiwan with a low prevalence rate of hepatitis B infection. HBsAg status, the presence of antibodies against HBsAg (anti-HBs), and the presence of antibod...

journal_title：Journal of medical virology

authors： Chu FY,Su FH,Cheng SH,Lin YS,Li CY,Chien CC,Lin YC,Chiang SY

更新日期：2011-09-01 00:00:00

abstract：:Infectivity of certain enteric viruses including rotavirus is profoundly affected by proteolytic enzymes. To test whether cystic fibrosis patients, possessing chronically decreased levels of pancreatic enzymes, show altered susceptibility to gastroenteritis viruses, we examined sera from patients and controls for anti...

journal_title：Journal of medical virology

authors： Cukor G,Blacklow NR,Braverman LE

更新日期：1982-01-01 00:00:00

abstract：:Hepatitis B e antigen (HBeAg)-negative chronic hepatitis B results from infection with hepatitis B virus mutants unable to produce HBeAg. It accounts for 7-30% of patients with chronic hepatitis B virus (HBV) worldwide, with the highest rates reported for Mediterranean Europe and Asia. Interferon (IFN) is currently th...

journal_title：Journal of medical virology

authors： Rizzetto M

更新日期：2002-04-01 00:00:00

abstract：:Variation at the IL-28B locus was recently reported to be a significant predictive factor of viral response to pegylated-interferon plus ribavirin combination therapy against chronic hepatitis C. Predictive factors for the effect of therapy, including IL-28B polymorphism rs8099917 and viral and clinical factors were i...

journal_title：Journal of medical virology

authors： Hashimoto Y,Ochi H,Abe H,Hayashida Y,Tsuge M,Mitsui F,Hiraga N,Imamura M,Takahashi S,Nelson Hayes C,Ohishi W,Kubo M,Tsunoda T,Kamatani N,Nakamura Y,Chayama K

更新日期：2011-06-01 00:00:00

abstract：:Kaposi's sarcoma-associated herpesvirus (KSHV), the etiologic agent of Kaposi's sarcoma, causes malignancies frequently in patients with acquired immunodeficiency syndrome. In the United States and Europe, KSHV infection is common among men who have sex with men. However, the seroprevalence of KSHV among men who have ...

journal_title：Journal of medical virology

authors： Katano H,Yokomaku Y,Fukumoto H,Kanno T,Nakayama T,Shingae A,Sugiura W,Ichikawa S,Yasuoka A

更新日期：2013-06-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV) associated malignant tumor. Recently, cidofovir, an anti-viral drug which is an acyclic nucleoside analogue, has been reported to have an anti-tumor potential. Two patients with NPC, who had previously received multi-round therapy, were treated with cidofov...

journal_title：Journal of medical virology

authors： Yoshizaki T,Wakisaka N,Kondo S,Murono S,Shimizu Y,Nakashima M,Tsuji A,Furukawa M

更新日期：2008-05-01 00:00:00

abstract：:Polymorphisms upstream interleukin (IL)-28B gene and serum levels of interferon gamma inducible protein-10 (IP-10) are associated with spontaneous and treatment-induced hepatitis C virus (HCV) clearance. Patients with seronegative occult HCV infection are anti-HCV and serum HCV-RNA negative but have viral RNA in liver...

journal_title：Journal of medical virology

authors： Bartolomé J,Castillo I,Quiroga JA,Carreño V

更新日期：2016-02-01 00:00:00

abstract：:Herpes zoster is a common infectious disease that can result in significant acute and chronic morbidity. The safety and efficacy of once-daily oral valomaciclovir (EPB-348) was evaluated for non-inferiority to 3-times daily valacyclovir, an approved therapy. In this study, 373 immunocompetent adults with onset of a he...

journal_title：Journal of medical virology

authors： Tyring SK,Plunkett S,Scribner AR,Broker RE,Herrod JN,Handke LT,Wise JM,Martin PA,Valomaciclovir Zoster Study Group.

更新日期：2012-08-01 00:00:00

abstract：:The impact of cytomegalovirus (CMV) infection of the genital tract during pregnancy on adverse pregnancy outcomes is not understood fully. A real-time PCR assay was used to determine vaginal shedding of CMV in 993 healthy pregnant Japanese women and the results were compared with the outcome of pregnancy. CMV DNA was ...

journal_title：Journal of medical virology

authors： Tanaka K,Yamada H,Minami M,Kataoka S,Numazaki K,Minakami H,Tsutsumi H

更新日期：2006-06-01 00:00:00

abstract：:Human herpesvirus 6 (HHV-6) prototype isolate GS is a newly identified lymphotropic herpesvirus and several subsequent herpes isolates were recognized as HHV-6 by their hybridization to a HHV-6(GS) DNA probe pZVH14. DNA restriction analysis and in vitro tropism studies show that HHV-6 isolates can be divided into two ...

journal_title：Journal of medical virology

authors： Chandran B,Tirawatnapong S,Pfeiffer B,Ablashi DV

更新日期：1992-08-01 00:00:00

abstract：:Enterovirus 71 H (E71 H), an isolate from an adult patient with hand-food-mouth disease (HFMD) in China, was serologically similar to the prototype strain E71 BrCr, which was isolated from a patient with aseptic meningitis. The study further analyzed the similarity of E71 H to E71 BrCr at the 5'-noncoding region (NCR)...

journal_title：Journal of medical virology

authors： Zheng ZM,He PJ,Caueffield D,Neumann M,Specter S,Baker CC,Bankowski MJ

更新日期：1995-10-01 00:00:00

abstract：:HPV infection is a "necessary cause" of cervical cancer and it is sexually transmitted. Due to upcoming mass vaccination investigation on risk factors for infection is the basis to implement prophylactic strategy even in older women. The aim of the study was to evaluate predictors of high-risk (HR) HPV infection in ad...

journal_title：Journal of medical virology

authors： Cercato MC,Mariani L,Vocaturo A,Carrone A,Terrenato I,Morano G,Benevolo M,Rollo F,Germelli C,Paolini F,Venuti A

更新日期：2010-11-01 00:00:00

abstract：:Epstein-Barr virus (EBV)-associated post-transplant lymphoproliferative disease (PTLD) arises in up to 10% of organ transplant recipients and is fatal in ∼50% of cases. PTLD can be modeled in SCID mice using EBV+ve human B lymphoblastoid cell lines (BLCLs), and the current study investigated intraperitoneal (ip) inocu...

journal_title：Journal of medical virology

authors： Johannessen I,Bieleski L,Urquhart G,Watson SL,Wingate P,Haque T,Crawford DH

更新日期：2011-09-01 00:00:00

abstract：:Norovirus (NoV) is a causative agent of gastroenteritis in children and adults worldwide. Although reverse transcription-polymerase chain reaction (RT-PCR) has been accepted as the standard method for diagnosis of NoV infection, it requires well-trained personnel and sophisticated equipments. Performance of a commerci...

journal_title：Journal of medical virology

authors： Thongprachum A,Khamrin P,Chaimongkol N,Malasao R,Okitsu S,Mizuguchi M,Maneekarn N,Ushijima H

更新日期：2010-12-01 00:00:00

abstract：:Coinfections with multiple types of human papillomavirus (HPV) occur in cervical adenocarcinoma (ADC). However, it remains unclear the clustering patterns of multiple types in HPV coinfections and relevant factors in ADC. A total of 718 paraffin-embedded ADC specimens were collected in China and tested for HPV genotyp...

journal_title：Journal of medical virology

authors： Dong L,Li T,Li L,Wang MZ,Wu Z,Cui J,Liu B,Zhang X,Qiao Y,Chen W

更新日期：2019-11-01 00:00:00

abstract：:Elevated telomerase activity is observed in about 90% of human cancers. This activity correlates strictly with human telomerase reverse transcriptase (hTERT). Previously, it was shown that the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) induced telomerase activity in nasopharyngeal carcinoma cells. In ...

journal_title：Journal of medical virology

authors： Ding L,Li L,Yang J,Zhou S,Li W,Tang M,Shi Y,Yi W,Cao Y

更新日期：2007-08-01 00:00:00

abstract：:Capillary blood of febrile children was lysed by using a lysis buffer containing ascorbic acid. MxA quantitation was performed by an immunochemiluminescent assay. The MxA values were significantly higher in capillary blood of infants with viral infections due to adenovirus (n = 5), rotavirus (n = 15), or respiratory s...

journal_title：Journal of medical virology

authors： Chieux V,Hober D,Chehadeh W,Harvey J,Alm G,Cousin J,Ducoulombier H,Wattre P

更新日期：1999-12-01 00:00:00

abstract：:This investigation is in continuation with the earlier studies on diarrhea epidemic due to rotavirus, that occurred at Jawhar western India, among tribal children during Dec 2000-Jan 2001 published by National Institute of Virology, Pune. Three rotavirus strains were isolated in cell culture from fecal specimens of af...

journal_title：Journal of medical virology

authors： Awachat PS,Kelkar SD

更新日期：2005-09-01 00:00:00

abstract：:Primary infection, seroconversion, and transmitted drug resistance (TDR) during pregnancy may influence the risk of mother-to-child-transmission (MTCT) of HIV-1 infection. This study estimated recent seroconversion, TDR rates, HIV-1 subtypes and pregnancy outcomes among 95 recently diagnosed, antiretroviral (ARV)-naïv...

journal_title：Journal of medical virology

authors： Lima YA,Cardoso LP,Reis MN,Stefani MM

更新日期：2016-11-01 00:00:00

abstract：:GB virus C/hepatitis G virus (GBV-C/HGV) is related distantly to hepatitis C virus (HCV). HCV has a hypervariable region (HVR), and exists as quasispecies in vivo. Although GBV-C/HGV also has replaceable amino acids in the presumed antigenic region, the existence and fluctuation of population of heterogeneous virus ha...

journal_title：Journal of medical virology

authors： Kato T,Mizokami M,Nakano T,Orito E,Ohba K,Kondo Y,Tanaka Y,Ueda R,Mukaide M,Fujita K,Yasuda K,Iino S

更新日期：1998-06-01 00:00:00

abstract：:It has been generally believed that the Epstein-Barr virus (EBV)-encoded small RNA 1 and 2 (EBER1 and EBER2) genes are conserved as two families that correlated with type 1 (B95-8) and type 2 (AG876 or P3HR-1) EBV strains. EBER polymorphism and its association with EBV-associated disease have not received much attenti...

journal_title：Journal of medical virology

authors： Wang Y,Zhang X,Chao Y,Jia Y,Xing X,Luo B

更新日期：2010-05-01 00:00:00

abstract：:The prevalence of picobirnaviruses (PBVs) in human stools was investigated by polyacrylamide gel electrophoresis (PAGE) analysis of 832 faecal specimens collected between 1982 and 1993 from patients in various clinical groups. Similar prevalences (9-13%) were detected in patients with or without gastroenteritis and th...

journal_title：Journal of medical virology

authors： Gallimore CI,Appleton H,Lewis D,Green J,Brown DW

更新日期：1995-02-01 00:00:00

abstract：:The human papillomavirus (HPV) 16 genome has been studied extensively, although no study has focused on the E1 gene that is implicated in viral DNA replication. After analyzing the E1 region of HPV 16 genomes in 429 cervical samples, 11.2% were found to contain a 63 nucleotides duplication in this region. Sequence ana...

journal_title：Journal of medical virology

authors： Sabol I,Matovina M,Gasperov NM,Grce M

更新日期：2008-12-01 00:00:00

abstract：:The aetiological agents responsible for, and the outcome of, acute liver failure were investigated prospectively in 44 children (29 males, 15 females) attending a tertiary health care facility in India. The children were between the ages of 2 months and 13 years. Studies for viral infections and other etiologies could...

journal_title：Journal of medical virology

authors： Arora NK,Nanda SK,Gulati S,Ansari IH,Chawla MK,Gupta SD,Panda SK

更新日期：1996-03-01 00:00:00