Abstract:
:Infectivity of certain enteric viruses including rotavirus is profoundly affected by proteolytic enzymes. To test whether cystic fibrosis patients, possessing chronically decreased levels of pancreatic enzymes, show altered susceptibility to gastroenteritis viruses, we examined sera from patients and controls for antibodies to two major pathogens. In cystic fibrosis patients, normal rotavirus antibody levels were found and Norwalk virus antibody prevalence was unchanged.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Cukor G,Blacklow NR,Braverman LEdoi
10.1002/jmv.1890090302subject
Has Abstractpub_date
1982-01-01 00:00:00pages
161-4issue
3eissn
0146-6615issn
1096-9071journal_volume
9pub_type
杂志文章abstract::Hepatitis C virus (HCV) exposure in blood donors is determined serologically by the detection of anti-HCV antibodies in serum or plasma. However, a "window" period of 30-70 days after exposure exists where specific antibodies to HCV antigens are not detected. The use of nucleic acid testing for the detection of HCV RN...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20716
更新日期:2006-11-01 00:00:00
abstract::HCV strains belonging to genotype 4 may be gaining endemicity across Continental Europe but the extent of their spread in the United Kingdom is unknown. Sera referred from patients attending hospitals in England between 2004 through 2008 were characterised. A total of 243 sera carried HCV genotype 4. The most common s...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24069
更新日期:2015-03-01 00:00:00
abstract::Investigation of varicella-zoster virus (VZV) is important epidemiologically, and determination of its prevalence rate in human trigeminal ganglia is important to provide surveillance data. To date, studies on VZV detection in trigeminal ganglia have used specimens obtained from a relatively limited number of cadavers...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21687
更新日期:2010-02-01 00:00:00
abstract::The human parvovirus B19 (B19) usually causes a subclinical infection in immunocompetent individuals. Whereas immunocompromised individuals such as patients infected with HIV are at risk of persistent anemia due to B19 infection. Only few studies have been carried out on distribution and molecular epidemiology of B19 ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24169
更新日期:2015-07-01 00:00:00
abstract::Little is known on the association between clinical factors and coronavirus disease 2019 (COVID-19) more than 15 days after diagnosis. We conducted a multicentric prospective cohort of COVID-19 hospitalized patients to describe clinical, biological, and virological characteristics at hospital admission and over time, ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.26601
更新日期:2020-10-15 00:00:00
abstract::We studied the role of sexual transmission in the epidemiology of HCV by a cross-sectional study comparing prostitutes and HCV seropositive and seronegative sexual clients recruited from the bordellos of the docks of Santos, São Paulo State. The average age in the prostitute group was 27.2 years. The median time spent...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:1997-04-01 00:00:00
abstract::Antibodies to herpes simplex virus and Epstein-Barr virus were sought in the sera of 33 patients with endoscopically proved duodenal ulcer and 33 healthy controls. Neither the prevalence nor the antibody levels to both viruses were significantly different between the two groups. These results suggest that herpes virus...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890290314
更新日期:1989-11-01 00:00:00
abstract::GB virus C (GBV-C) is related to hepatitis C virus (HCV) and has a similar genomic structure. Some predictors for the efficacy of interferon (IFN) therapy on HCV have been reported: genotype, viral load, IFN dose, and the amino acid substitutions in the NS5A region, designated as the interferon sensitivity determining...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9071(199904)57:4<376::aid-jmv9>
更新日期:1999-04-01 00:00:00
abstract::There are contradictory reports regarding the effects of inhalation anesthetics on the immune system. Measurable immune responses have been studied in vitro, but little is known about the in vivo effects in the intact organism. We used an attenuated, non-neuroinvasive, nonlethal strain of the encephalitic West Nile vi...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.2184
更新日期:2002-04-01 00:00:00
abstract::The efficacy of interferon therapy for hepatitis C virus (HCV) infection improved remarkably. However, virologic relapse occurs in a substantial proportion of patients with virologic response (defined as an HCV RNA level below 50 IU/ml at the end-of-treatment). A highly sensitive RT-nested PCR assay capable of detecti...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20908
更新日期:2007-08-01 00:00:00
abstract::The genotypes and subtypes of 205 HBV isolates collected during 1989-2002 in Estonia and 14 other regions of the former USSR were determined by sequencing and phylogenetic analysis of the S gene. The in Europe prevailing genotypes, A and D, were also circulating in the whole territory of the former USSR including Esto...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20169
更新日期:2004-10-01 00:00:00
abstract::Taiwan was a hyperendemic area for hepatitis A and B viruses (HAV and HBV) infection before late 1980s. To study the seroprevalence of hepatitis A, B, C, and E viruses (HCV and HEV) infection among preschool children in Taiwan, a community-based survey was carried out in 54 kindergartens in 10 urban areas, 10 rural ar...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20517
更新日期:2006-01-01 00:00:00
abstract::Infection with oncogenic human papillomavirus (HPV) genotypes is necessary for the development of cervical cancer. Testing for HPV DNA from liquid based cervical samples can be used as an adjunct to traditional cytological screening. In addition there are ongoing viral load, genotyping, and prevalence studies. Therefo...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23882
更新日期:2014-04-01 00:00:00
abstract::Human T-cell lymphotropic virus 1 (HTLV-1) is associated with two progressive diseases: HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukemia/lymphoma (ATLL). Although HTLV-1 proviral load (PVL) has been introduced as a risk factor for these diseases' progression, it is not suff...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24721
更新日期:2017-06-01 00:00:00
abstract::The risk and clearance of GB virus type C (GBV-C)/hepatitis G virus (HGV) infection was investigated in a cohort of homosexual men (n=180; median follow-up time, 7 years). The interaction between GBV-C/HGV RNA and antibodies against the E2 region of the virus, and the clinical impact of chronic GBV-C/HGV infection wer...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9071(199911)59:3<303::aid-jmv7>
更新日期:1999-11-01 00:00:00
abstract::With virus-infected autologous and allogenic mononuclear cells as specific targets, the development of cell-mediated cytotoxic reactivity to respiratory syncytial virus (RSV) was studied in peripheral blood lymphocytes (PBL) in groups of infants with acute RSV infection and in other control groups of subjects during a...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890280304
更新日期:1989-07-01 00:00:00
abstract::Resistance to adamantanes for treating influenza A(H3N2) has increased dramatically, worldwide, over the past 5 years. A comprehensive 10-year data set on the rise of adamantane-resistance in Hong Kong is reported. Nucleotide sequences encoding the M2-ion channel of influenza A(H3N2) were obtained from 281 H3N2 isolat...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21155
更新日期:2008-05-01 00:00:00
abstract::The 70 kDa heat shock protein (Hsp70) is generally considered to be an intracellular protein, however, there is evidence that Hsp70 can be found in the extracellular environment. Hsp70 and antibodies against Hsp70 have been reported in human serum. Recent evidence has shown that Hsp70 antibodies are elevated in HIV in...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20384
更新日期:2005-08-01 00:00:00
abstract::In order to shed light on the mode of HTLV-I infection by mother-to-child transmission, we examined sera of school children in a highly endemic town on two separate occasions at a 6-year interval. The carrier rates in ages 15-17, 8.7 and 2.1%, were significantly higher than that in ages 6-8, 1.7 and 0.4%, in studies. ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890200307
更新日期:1986-11-01 00:00:00
abstract::Human metapneumovirus, with two known genotypes named A and B, is associated with mild respiratory symptoms to severe LRTI in children, high-risk adults and the elderly. Rapid and reliable methods of hMPV detection in clinical samples are essential to implement appropriate care, to better understand the pathology of h...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21038
更新日期:2008-01-01 00:00:00
abstract::Corticosteroid use in transplant recipients increases the incidence and severity of Kaposi's sarcoma (KS), a disease associated with KS-associated herpesvirus (KSHV) infection. Recently, the prototypic corticosteroid, hydrocortisone, was shown to directly induce lytic cycle reactivation of KSHV in latently-infected BC...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.2155
更新日期:2002-03-01 00:00:00
abstract::Persistent Epstein-Barr virus (EBV) infection is controlled tightly by virus-specific T cells. EBV infection is reactivated intermittently over time, even in apparently healthy carriers. Changes in frequency and reactivity of memory T cells, particularly of CD8(+) origin, have not been assessed in this context. It is ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22258
更新日期:2012-01-01 00:00:00
abstract::Dried blood spots collected on filter paper are considered potential clinical specimens for measles surveillance because of their ease of collection, storage, and transport. The usefulness of these samples for surveillance of measles was evaluated in a field setting. Blood spots were collected by finger-prick from 316...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20136
更新日期:2004-08-01 00:00:00
abstract::Rotaviruses are the major etiological agents of diarrhea in children less than 5 years of age. The commonest G types in humans are G1-4 and G9. G12 is a rare human rotavirus (HRV) strain first reported in the Philippines. In this study, 13 G12 strains obtained from a community-based cohort and a hospital-based surveil...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20872
更新日期:2007-09-01 00:00:00
abstract::An anti-hepatitis A virus (HAV)-specific immunoglobulin M capture enzyme-linked immunosorbent assay (anti-HAV IgM ELISA) kit was re-designed for laboratory use and compared with a commercial anti-HAV IgM detection system using 58 serum samples collected from patients, vaccines, and healthy individuals. Because concord...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21578
更新日期:2009-09-01 00:00:00
abstract::Hepatitis B virus (HBV) DNA may persist in the liver in the absence of serum HBV-DNA after a self-limited acute hepatitis B. This may also occur in patients with chronic hepatitis C virus (HCV) infection but its prevalence and its impact on liver histology is unknown. HBV-DNA was tested by polymerase chain reaction (P...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20073
更新日期:2004-06-01 00:00:00
abstract::Junin virus infection in guinea pigs is known to be similar to human Argentine hemorrhagic fever (AHF). The guinea pig was chosen as a model for transplacental transmission of Junin virus, as both guinea pig and man have a similar placental structure. Pregnant guinea pigs were infected with the pathogenic XJ strain of...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890110210
更新日期:1983-01-01 00:00:00
abstract::Immunoglobulin G (IgG) and M (IgM) antibodies against mumps virus were measured by an enzyme-linked immunosorbent assay (ELISA) in the serum and cerebrospinal fluid (CSF) specimens of patients with mumps meningitis. The CSF IgG antibodies correlated well with the respective antibody titers in serum. On the contrary, i...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890080406
更新日期:1981-01-01 00:00:00
abstract::Respiratory viruses were identified by the polymerase chain reaction (PCR) in more than 4,200 specimens collected during 2002 and 2003 in Victoria, Australia from patients admitted to hospitals or participating in an influenza surveillance program. Influenza viruses and picornaviruses were important causes of morbidit...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20246
更新日期:2005-01-01 00:00:00
abstract::Hepatitis B virus (HBV) infection is a dynamic process during which molecular variants are selected continuously to adapt to changes. In addition to drug resistant mutations, sequential antiviral therapy may also lead to the selection of deleted mutants. To investigate this process, the following samples were collecte...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21595
更新日期:2009-09-01 00:00:00