An in-house-anti-hepatitis A virus (HAV)-specific immunoglobulin M capture enzyme-linked immunosorbent assay: evaluation and application to an HAV outbreak.

abstract：:Molecular investigation was undertaken of circulating hepatitis A virus (HAV) associated with cases of acute diarrhea among children under 5 years of age in Kumba-Cameroon. Reverse transcription PCR, sequencing, and phylogenetic analysis of a 371 bp segment of the VP1/P2A junction of six isolates obtained from stool s...

journal_title：Journal of medical virology

authors： Forbi JC,Agwale SM,Ndip LM,Esona MD

更新日期：2012-05-01 00:00:00

abstract：:Chronic hepatitis B patients with low pre-treatment HBeAg (and HBV-DNA) levels are more likely to respond to interferon-alpha therapy. In retrospect, this low level of HBeAg may have been reached just before the start of therapy. Pre-treatment changes in HBeAg levels were studied in 121 patients undergoing interferon-...

journal_title：Journal of medical virology

authors： Heijtink RA,Janssen HL,Hop WC,Osterhaus AD,Schalm SW

更新日期：2001-03-01 00:00:00

abstract：:Hepatitis C virus (HCV) has infected approximately 170 million people worldwide. While the seroprevalence of anti-HCV antibody among Iranian blood donors is 0.13%, HCV infection is prevalent in 59-80% of Iranian injecting drug users. One hundred seventy-eight anti-HCV positive patients were referred to the Gastroenter...

journal_title：Journal of medical virology

authors： Salehi Moghadam F,Mohebbi SR,Hosseini SM,Romani S,Mirtalebi H,Azimzadeh P,Damavand B,Naghoosi H,Khanyaghma M,Sanati A,Zali MR

更新日期：2014-08-01 00:00:00

abstract：:This study aimed to investigate the prevalence trend of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections and their genotype distribution among hemodialysis patients, determining their long-term prognosis and the risk factors to the mortality. This cohort study used both the medical data and the blood sam...

journal_title：Journal of medical virology

authors： Ko K,Nagashima S,Yamamoto C,Takahashi K,Matsuo J,Ohisa M,Akita T,Matyakubov J,Mirzaev U,Katayama K,Masaki T,Tanaka J

更新日期：2020-06-24 00:00:00

abstract：:This study describes two measles outbreaks--one in Cape Town, South Africa in November 2002, and the other in Luanda, Angola in March 2003. The outbreaks were notable because they were caused by closely related genotype B2 viruses. This genotype was first described in an outbreak in Libreville, Gabon in the 1980s and ...

journal_title：Journal of medical virology

authors： Smit SB,Hardie D,Tiemessen CT

更新日期：2005-12-01 00:00:00

abstract：AIMS:To investigate the association between two RIG-I-like receptor gene polymorphisms and hepatitis C virus (HCV) infection in Chinese Han population. METHODS:The current study genotyped two selected SNPs (IFIH1 rs3747517 and DDX58 rs9695310) using TaqMan allelic discrimination assay to assess their association with ...

journal_title：Journal of medical virology

authors： Zhu XB,Zhuo LY,Yue M,Liu M,Zang F,Fan HZ,Wu JJ,Xia XS,Zhang AM,Yu RB,Huang P

更新日期：2019-06-01 00:00:00

abstract：:Ultra violet (UV) light-inactivated measles virus was used for the lymphocyte proliferation assay, where it caused consistently adult human peripheral blood monolymphocytes (PBML) proliferation which was not dependent on the measles virus complement fixation titre in the donor's sera. When the cord blood lymphocytes f...

journal_title：Journal of medical virology

authors： Tu R

更新日期：1995-06-01 00:00:00

abstract：:To elucidate the mechanism of heterologous antibody responses to herpes simplex virus (HSV) and varicella-zoster virus (VZV) which occur in some patients with HSV or VZV infections, stronger evidence was sought for the existence of cross-reacting antibodies to these viruses, using antibody absorption procedures. Absor...

journal_title：Journal of medical virology

authors： Schmidt NJ

更新日期：1982-01-01 00:00:00

abstract：:Complete coding regions were sequenced for two new enterovirus genomes: EV-B93 previously identified by VP1 sequencing, derived from a child with acute flaccid paralysis in the Democratic Republic of Congo; and EV-C95 from a French soldier with acute gastroenteritis in Djibouti. The EV-B93 P1 had more than 30% nucleot...

journal_title：Journal of medical virology

authors： Junttila N,Lévêque N,Magnius LO,Kabue JP,Muyembe-Tamfum JJ,Maslin J,Lina B,Norder H

更新日期：2015-03-01 00:00:00

abstract：:Flow cytometric analysis of CD4(+) and CD8(+) T cells specific to human cytomegalovirus (CMV) was undertaken in seven patients with congenital CMV infection, six healthy infants who had acquired infection, and six CMV-seropositive adults. Intracellular cytokine assays showed that 0.03-2.23% of CD4(+) T cells in the he...

journal_title：Journal of medical virology

authors： Hayashi N,Kimura H,Morishima T,Tanaka N,Tsurumi T,Kuzushima K

更新日期：2003-10-01 00:00:00

abstract：:The impact of dynamic respiratory syncytial virus (RSV) load on the clinical severity of hospitalized infants with bronchiolitis has not been clarified. Nasopharyngeal aspirates were obtained from 60 infants who were diagnosed with bronchiolitis within 96 hr of wheezing onset upon admission and on days 3, 5, and 7 in ...

journal_title：Journal of medical virology

authors： Zhou L,Xiao Q,Zhao Y,Huang A,Ren L,Liu E

更新日期：2015-08-01 00:00:00

abstract：UNLABELLED:Viral respiratory tract infections in lung transplant recipients may be severe. During three consecutive winter-spring seasons, 49 symptomatic lung transplant recipients with suspected respiratory viral infection, and 26 asymptomatic patients were investigated for presence of respiratory viruses either in 56...

journal_title：Journal of medical virology

authors： Gerna G,Vitulo P,Rovida F,Lilleri D,Pellegrini C,Oggionni T,Campanini G,Baldanti F,Revello MG

更新日期：2006-03-01 00:00:00

abstract：:The seroprevalences of hepatitis B virus (HBV) and hepatitis C virus (HCV) markers were evaluated in a random sample of 803 children attending school in Ashanti-Akim North district in Ghana in order to gain a better understanding of transmission patterns of these viruses, particularly horizontal transmission of HBV. T...

journal_title：Journal of medical virology

authors： Martinson FE,Weigle KA,Mushahwar IK,Weber DJ,Royce R,Lemon SM

更新日期：1996-03-01 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) circulating recombinant form (CRF) 07_BC strain has caused serious outbreaks among injection drug users in Taiwan since 2004. The objective of this study was to conduct a molecular epidemiological study of HCV genotypes in intravenous drug users in Taiwan. Blood samples and ...

journal_title：Journal of medical virology

authors： Lee YM,Lin HJ,Chen YJ,Lee CM,Wang SF,Chang KY,Chen TL,Liu HF,Chen YM

更新日期：2010-01-01 00:00:00

abstract：:JC and BK polyomaviruses (JCV and BKV) infect humans and can cause severe illnesses in immunocompromised patients. Merkel cell polyomavirus (MCPyV) can be found in skin carcinomas. In this study, we assessed the occurrence of serum antibodies against MCPyV, BKV, and JCV polyomaviruses in a healthy population of the Cz...

journal_title：Journal of medical virology

authors： Sroller V,Hamšíková E,Ludvíková V,Vochozková P,Kojzarová M,Fraiberk M,Saláková M,Morávková A,Forstová J,Němečková S

更新日期：2014-09-01 00:00:00

abstract：:The effect of antiviral treatment on apoptosis in chronic hepatitis B (CHB) has not been clarified. We evaluated the hepatic immunohistochemical expression of the pro-apoptotic bax and the antiapoptotic bcl-xL protein in HBeAg-negative CHB patients before and after treatment. In our study we included 72 paired biopsie...

journal_title：Journal of medical virology

authors： Cholongitas E,Papatheodoridis GV,Manesis EK,Petraki K,Tiniakos D,Hadziyannis SJ

更新日期：2011-07-01 00:00:00

abstract：:The relative frequency and distribution of the VP4 (P) genotypes of 227 human rotavirus field strains were investigated in South Africa. The stool samples were collected between 1984-1993 from infants and young children with diarrhea at Ga-Rankuwa Hospital, Pretoria, South Africa. The RNA was extracted from stools, he...

journal_title：Journal of medical virology

authors： Mphahlele MJ,Steele AD

更新日期：1995-09-01 00:00:00

abstract：:Asymptomatic carriers have a major influence on the spreading of norovirus infections. The objective of this study was to examine the characteristics of patients and asymptomatic carriers affected by norovirus-related community gastroenteritis outbreaks. No significant difference between the two groups was observed in...

journal_title：Journal of medical virology

authors： Mori K,Konishi N,Suzuki Y,Harada S,Maeda M,Akase S,Obata H,Monma C,Nagano M,Kimoto K,Oda M,Somura Y,Hirai A,Shinkai T,Noda M,Sadamasu K

更新日期：2018-12-01 00:00:00

abstract：:During the period between 1998 and 2008, 48 representative measles viruses (MeVs) circulating in Thailand were subjected to genetic characterization. Three genotypes, G2, D5, and D9 were detected. The results suggested that measles genotype D5, which has been circulating since at least 1998, is the endemic genotype in...

journal_title：Journal of medical virology

authors： Pattamadilok S,Incomserb P,Primsirikunawut A,Lukebua A,Rota PA,Sawanpanyalert P

更新日期：2012-05-01 00:00:00

abstract：:Nutrient starvation is a common phenomenon that occurs during T cell activation. Upon pathogen infection, large amounts of immune cells migrate to infection sites, and antigen-specific T cells are activated; this is followed by rapid proliferation through clonal expansion. The dramatic expansion of cells will commonly...

journal_title：Journal of medical virology

authors： Lu J,Jia J,Zhang J,Liu X

更新日期：2020-08-13 00:00:00

abstract：:During 2002, several epidemics of aseptic meningitis were attributed to echovirus 13 in Korea. The causative agents of these outbreaks were isolated and identified using rhabdosarcoma cells, HEp-2 and Buffalo green monkey kidney cells, and a neutralization test using monospecific antiserum. Fifty-four echovirus 13 iso...

journal_title：Journal of medical virology

authors： Cheon DS,Lee J,Lee K,Lee S,Park K,Ahn J,Jee Y,Yoon J,Cho H

更新日期：2004-07-01 00:00:00

abstract：:Genetically different subpopulations were identified and purified from Japanese Encephalitis virus (JEV). Those with small plaques (SPs; <2 mm in diameter), derived from strains of T1P1, CJN, and CC27, were more competent than those with large plaques (LPs; >5 mm in diameter) when passaged in Neuro-2a cells. Differenc...

journal_title：Journal of medical virology

authors： Chiou SS,Liu H,Chuang CK,Lin CC,Chen WJ

更新日期：2005-08-01 00:00:00

abstract：:Until recently, human cytomegalovirus (hCMV) infection and anti-CMV treatment in transplanted patients have been monitored essentially by pp65 antigenemia, which is time-consuming and requires experienced operators. For the last two years, pp65 antigenemia levels have tended to be lower than previously in our laborato...

journal_title：Journal of medical virology

authors： Schvoerer E,Henriot S,Zachary P,Freitag R,Fuchs A,Fritsch S,Risch S,Meyer N,Caillard S,Lioure B,Stoll-Keller F

更新日期：2005-05-01 00:00:00

abstract：:The efficacy of interferon (IFN) monotherapy for non-responders to pegylated interferon (PEG-IFN) plus ribavirin (RBV) combination therapy is still unclear. To evaluate the impact of IFN monotherapy on biochemical response, 200 consecutive patients infected with HCV genotype 1b, who received low-dose intermittent IFN-...

journal_title：Journal of medical virology

authors： Akuta N,Suzuki F,Kawamura Y,Yatsuji H,Sezaki H,Suzuki Y,Hosaka T,Kobayashi M,Kobayashi M,Arase Y,Ikeda K,Kumada H

更新日期：2008-08-01 00:00:00

abstract：:A new assay was developed for the detection of hepatitis B virus (HBV) in human serum using amplification of a short viral DNA sequence by means of the polymerase chain reaction. As little as 0.4 fg viral DNA, corresponding to about 130 genome equivalents, per ml serum could be detected after the amplification procedu...

journal_title：Journal of medical virology

authors： Sumazaki R,Motz M,Wolf H,Heinig J,Jilg W,Deinhardt F

更新日期：1989-04-01 00:00:00

abstract：:To elucidate the relationship between the clinical severity of chronic liver disease and the precore mutations in hepatitis B e antigen (HBeAg)-negative hepatitis B virus (HBV) carriers, mutations were investigated in the precore region of HBV DNA in 20 chronic hepatitis B patients who seroconverted either spontaneous...

journal_title：Journal of medical virology

authors： Karasawa T,Aizawa Y,Zeniya M,Kuramoto A,Shirasawa T,Toda G

更新日期：1995-04-01 00:00:00

abstract：:SARS-CoV-2 infection is causing a pandemic disease that is reflected in challenging public health problems worldwide. Human leukocyte antigen (HLA)-based epitope prediction and its association with disease outcomes provide an important base for treatment design. A bioinformatic prediction of T cell epitopes and their ...

journal_title：Journal of medical virology

authors： Romero-López JP,Carnalla-Cortés M,Pacheco-Olvera DL,Ocampo-Godínez JM,Oliva-Ramírez J,Moreno-Manjón J,Bernal-Alferes B,López-Olmedo N,García-Latorre E,Domínguez-López ML,Reyes-Sandoval A,Jiménez-Zamudio L

更新日期：2020-09-28 00:00:00

abstract：:The efficacy of interferon therapy for hepatitis C virus (HCV) infection improved remarkably. However, virologic relapse occurs in a substantial proportion of patients with virologic response (defined as an HCV RNA level below 50 IU/ml at the end-of-treatment). A highly sensitive RT-nested PCR assay capable of detecti...

journal_title：Journal of medical virology

authors： Kinai E,Hanabusa H,Kato S

更新日期：2007-08-01 00:00:00

abstract：:The use of new Direct Acting Antivirals, specific of HCV, has greatly improved the HCV treatment. Most of the DAA are specific of HCV genotypes. Genotyping methods may target different regions of the HCV genome, though only the whole genome sequencing could confirm the correct genotype. The present study describes the...

journal_title：Journal of medical virology

authors： Mourez T,Decroos A,Goria O,Montialoux H,De Oliveira F,Larrat S,Plantier JC,Riachi G

更新日期：2018-05-01 00:00:00

abstract：:Human immunodeficiency virus 2 (HIV-2) infection is characterized by a slower disease progression and lower transmission rates. The molecular features that could be assigned as directly involved in this in vivo phenotype remain essentially unknown, and the importance of HIV-2 as a model to understand pathogenicity of ...

journal_title：Journal of medical virology

authors： Santos-Costa Q,Parreira R,Moniz-Pereira J,Azevedo-Pereira JM

更新日期：2009-11-01 00:00:00