Seroepidemiology of hepatitis A, B, C, and E viruses infection among preschool children in Taiwan.

Abstract:

:Taiwan was a hyperendemic area for hepatitis A and B viruses (HAV and HBV) infection before late 1980s. To study the seroprevalence of hepatitis A, B, C, and E viruses (HCV and HEV) infection among preschool children in Taiwan, a community-based survey was carried out in 54 kindergartens in 10 urban areas, 10 rural areas, and 2 aboriginal areas randomly selected through stratified sampling. Serum specimens of 2,538 preschool children were screened for the hepatitis A, C, and E antibodies by a commercially available enzyme immunoassay and for HBV markers by radioimmunoassay methods. The multivariate-adjusted odd ratios (OR) with their 95% confidence intervals (CI) were estimated through the multiple logistic regression analysis. Females had a statistically significantly higher HAV seroprevalence than males. The seroprevalence of HCV infection increased significantly with age. The larger the sibship size, the higher the seroprevalence of HBV infection. Aboriginal children had a significantly higher seroprevalence of HBV and HEV infection and lower seroprevalence of HCV infection than non-aboriginal children. A significantly higher seroprevalence of HBV infection was found in rural children than urban children. There was no significant association between serostatus of HAV and HEV infection and between serostatus of HBV and HCV infection among preschool children in Taiwan. The poor environmental and hygienic conditions in the aboriginal areas might play a role in infection with HBV and HEV.

journal_name

J Med Virol

authors

Lin JB,Lin DB,Chen SC,Chen PS,Chen WK

doi

10.1002/jmv.20517

keywords:

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

18-23

issue

1

eissn

0146-6615

issn

1096-9071

journal_volume

78

pub_type

杂志文章
  • Molecular characterization of human respiratory syncytial virus subtype B: a novel genotype of subtype B circulating in China.

    abstract::Human respiratory syncytial virus (HRSV) is major pathogen of lower respiratory tract infections in infants and young children worldwide. There have been many studies regarding HRSV subgroup A (HRSV-A) G protein genetic variability but little information about HRSV subtype B (HRSV-B) G protein genetic diversity and mo...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23960

    authors: Ren L,Xiao Q,Zhou L,Xia Q,Liu E

    更新日期:2015-01-01 00:00:00

  • Characteristics of lamivudine-resistant hepatitis B virus (HBV) strains with and without breakthrough hepatitis in patients with chronic hepatitis B evaluated by serial HBV full-genome sequences.

    abstract::Lamivudine therapy often causes breakthrough of hepatitis B virus (HBV) DNA and breakthrough hepatitis. The aim of this study was to determine the viral factors that relate to HBV-DNA breakthrough with and without breakthrough hepatitis. Among 82 patients with chronic hepatitis B (CHB) who received lamivudine at a dos...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20915

    authors: Horiike N,Duong TN,Michitaka K,Joko K,Hiasa Y,Konishi I,Yano M,Onji M

    更新日期:2007-07-01 00:00:00

  • Prevalence of CMV antibodies among women of childbearing age in different social environments in southern Israel.

    abstract::The prevalence rate of IgG antibodies to cytomegalovirus (CMV) was determined in a sample of 567 women of childbearing age in the southern part of Israel by the immunoperoxidase assay to membrane antigen (IPAMA) technique. Urban Jewish women of Afro-Asian origin showed significantly higher rates of seropositivity than...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890240104

    authors: Urkin J,Sarov B,Naggan L,Haikin H,Sarov I

    更新日期:1988-01-01 00:00:00

  • Intratonsillar detection of 27 distinct viruses: A cross-sectional study.

    abstract::Palatine tonsils have been observed to harbor several distinct respiratory and herpesviruses in separate studies. In this study, the presence of these viruses in palatine tonsils was comprehensively studied in both children and adults. A cross-sectional analysis of 181 patients (median age 22 years; range, 2.6-66) ope...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26245

    authors: Silvoniemi A,Mikola E,Ivaska L,Jeskanen M,Löyttyniemi E,Puhakka T,Vuorinen T,Jartti T

    更新日期:2020-06-30 00:00:00

  • Prevalence of HIV-1 non-B subtypes, syphilis, HTLV, and hepatitis B and C viruses among immigrant sex workers in Madrid, Spain.

    abstract::Sexually transmitted disease (STD) remains a major public health challenge in developed countries, exacerbated by the advent of the HIV epidemic. The objectives of this study were to assess the prevalence of serological markers of syphilis, HIV-1/2, HTLV-I/II, HBV, and HCV infections among immigrant sex workers in Mad...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20208

    authors: Gutiérrez M,Tajada P,Alvarez A,De Julián R,Baquero M,Soriano V,Holguín A

    更新日期:2004-12-01 00:00:00

  • Repression of tax-mediated human t-lymphotropic virus type 1 transcription by inducible cAMP early repressor (ICER) protein in peripheral blood mononuclear cells.

    abstract::Human T-lymphotropic virus type 1 (HTLV-1) infection causes adult T-cell leukemia and is characterized by long periods of clinical latency with low levels of viral production. Transcription of HTLV-1 is controlled through sequences in the promoter and enhancer regions of the long terminal repeat of the integrated prov...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Newbound GC,O'Rourke JP,Collins ND,Andrews JM,DeWille J,Lairmore MD

    更新日期:2000-10-01 00:00:00

  • Circulating immune complexes in chronic hepatitis C.

    abstract::For assessing the role of circulating immune complexes (CIC) in chronic hepatitis C, the relative frequency of CIC was determined in 54 patients with chronic hepatitis C, 15 asymptomatic hepatitis C virus (HCV) carriers, and 54 healthy controls. IgM and IgG containing CIC were studied using both C1q and conglutinin (K...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890460104

    authors: Tsai JF,Jeng JE,Chang WY,Ho MS,Lin ZY,Tsai JH

    更新日期:1995-05-01 00:00:00

  • Correlation between hepatitis B virus surface antigen level and alpha-fetoprotein in patients free of hepatocellular carcinoma or severe hepatitis.

    abstract::Alfa-fetoprotein (AFP) is used as a marker of early hepatocarcinogenesis. However, the impact of hepatitis B virus surface antigen (HBsAg) on this relationship in patients with HBV infection is not clear. The present study evaluated the relation between HBsAg and AFP levels at the initial visit in 1,610 untreated HBV ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23790

    authors: Akuta N,Suzuki F,Kobayashi M,Hara T,Sezaki H,Suzuki Y,Hosaka T,Kobayashi M,Saitoh S,Ikeda K,Kumada H

    更新日期:2014-01-01 00:00:00

  • ACE2, TMPRSS2, and Furin variants and SARS-CoV-2 infection in Madrid, Spain.

    abstract::It has been suggested that some individuals may present genetic susceptibility to SARS-CoV-2 infection, with particular research interest in variants of the ACE2 and TMPRSS2 genes, involved in viral penetration into cells, in different populations and geographic regions, although insufficient information is currently ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26319

    authors: Torre-Fuentes L,Matías-Guiu J,Hernández-Lorenzo L,Montero-Escribano P,Pytel V,Porta-Etessam J,Gómez-Pinedo U,Matías-Guiu JA

    更新日期:2021-02-01 00:00:00

  • Localization of CD8+ cells specific for hepatitis B virus surface protein in the liver of immunized mice.

    abstract::DNA plasmids are potent inducers of long-lasting antigen-specific CTL responses. Little is known about the distribution of antigen-specific CD8+ T cells in the lymphoid tissue and the non-lymphoid tissue after DNA immunization. HBsAg-specific CD8+ T cells in peripheral blood mononuclear cells, spleen, lymph nodes, and...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21039

    authors: Qu D,Lanier G,Yuan ZH,Wen YM,Howard CR,Ahmed R

    更新日期:2008-02-01 00:00:00

  • Comparative evaluation of measles virus-specific RT-PCR methods through an international collaborative study.

    abstract::Comparison of RT-PCR assays established in house at various places revealed that laboratories could differ in sensitivity by as much as 1,000-fold in terms of the ability to detect measles virus sequences in clinical samples. The study indicates that PCR findings, positive or negative, are questionable if they are not...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.10371

    authors: Afzal MA,Osterhaus AD,Cosby SL,Jin L,Beeler J,Takeuchi K,Kawashima H

    更新日期:2003-05-01 00:00:00

  • Brief report: parainfluenza virus type 3 infections: findings in Sydney and some observations on variations in seasonality world-wide.

    abstract::Parainfluenza virus type 3 (Para 3) is an important childhood pathogen causing a significant amount of bronchiolitis and pneumonia in infants. Virus data were analysed over a twelve-year period (1978-1989), and a peak incidence of infection was observed in spring as in Houston, USA, unlike in the United Kingdom where ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890350105

    authors: de Silva LM,Cloonan MJ

    更新日期:1991-09-01 00:00:00

  • Molecular characterization of serotype G9 rotaviruses circulating in South Korea between 2005 and 2010.

    abstract::A total of 18 rotavirus G9 strains in South Korea were collected during five rotavirus seasons between 2005 and 2010. The relationship between these strains was examined by analyzing the genetic variation of two major structural genes, VP7 and VP4. All the rotavirus isolates were of the G9P[8] genotype. The VP7 phylog...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23436

    authors: Than VT,Kang H,Lim I,Kim W

    更新日期:2013-01-01 00:00:00

  • Puumala virus and two genetic variants of Tula virus are present in Austrian rodents.

    abstract::Puumala and Tula viruses are hantaviruses found in Europe and are associated with the rodents Clethrionomys glareolus and Microtus arvalis, respectively. Puumala virus is associated with the human disease nephropathia epidemica. In Austria, ten clinically diagnosed cases of nephropathia epidemica, presumably caused by...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9071(199710)53:2<174::aid-jmv11

    authors: Bowen MD,Gelbmann W,Ksiazek TG,Nichol ST,Nowotny N

    更新日期:1997-10-01 00:00:00

  • Detection of HPV types and neutralizing antibodies in Gansu province, China.

    abstract::A total of 82 samples from patients with cervical cancer (Group 1) and 50 samples from patients with other genital diseases (Group 2) were collected in Gansu, China. All 132 samples were tested for HPV DNA with a typing kit that can detect 21 types of HPV, and also tested for neutralizing antibodies against HPV-16, -1...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21435

    authors: Wu X,Zhang C,Feng S,Liu C,Li Y,Yang Y,Gao J,Li H,Meng S,Li L,Zhang Y,Hu X,Wu X,Lin L,Li X,Wang Y

    更新日期:2009-04-01 00:00:00

  • Prevalence of unusual human rotavirus strains in Ghanaian children.

    abstract::Sixty-seven rotavirus-positive fecal samples, collected between January and April 1999, from children with diarrhea in the Upper East Region of Ghana were examined for rotavirus VP7 and VP4 types. Sufficient viral RNA could be obtained from 46 (68.7%) of the samples and all the isolates had short electrophoretic patte...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Armah GE,Pager CT,Asmah RH,Anto FR,Oduro AR,Binka F,Steele D

    更新日期:2001-01-01 00:00:00

  • Human metapneumovirus-associated hospital admissions over five consecutive epidemic seasons: evidence for alternating circulation of different genotypes.

    abstract::Human metapneumovirus (hMPV) is a pathogen of the respiratory tract with a worldwide distribution. The purpose of this study was to identify hMPV as the cause of acute respiratory diseases in children admitted at Spedali Civili, a public hospital in Brescia, Italy. Eight hundred forty-six nasopharyngeal aspirate sampl...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23213

    authors: Apostoli P,Zicari S,Lo Presti A,Ciccozzi M,Ciotti M,Caruso A,Fiorentini S

    更新日期:2012-03-01 00:00:00

  • Presence of Betapapillomavirus in Kaposi sarcoma lesions.

    abstract::Human herpes virus 8 (HHV 8) is recognized as the necessary cause of Kaposi sarcoma (KS) and in the recent past the human papillomavirus (HPV) has been linked to the development of cutaneous basal cell and squamous cell carcinomas. In a cross sectional study investigating Beta-HPV infections in skin lesions, an unexpe...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23944

    authors: Murahwa AT,Muchemwa FC,Duri K,Borok MZ,Kanyera RB,Manhanzva MT,Mapingure MP,Stray-Pedersen B

    更新日期:2014-09-01 00:00:00

  • Prevalence of drug resistance mutations in HAART patients infected with HIV-1 CRF06_cpx in Estonia.

    abstract::HIV-1 drug resistance mutations (DRMs) and substitutions were assessed after the failure of the first line non-nucleoside reverse transcriptase inhibitors (NNRTIs) + 2 nucleoside/nucleotide reverse transcriptase inhibitors (NRTIs) treatment regimens (efavirenz [EFV] + lamivudine[3TC] + zidovudine [ZDV] vs. EFV + 3TC +...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24361

    authors: Avi R,Pauskar M,Karki T,Kallas E,Jõgeda EL,Margus T,Huik K,Lutsar I

    更新日期:2016-03-01 00:00:00

  • Recovery of functional cytotoxic T lymphocytes during lamivudine therapy by acquiring multi-specificity.

    abstract::To characterize cytotoxic T lymphocytes (CTLs) that appeared in circulation during lamivudine therapy, we analyzed HBV-specific CTLs using HLA-A24 tetramer and HBcAg-specific Th1 cells in patients receiving lamivudine therapy. Six patients (HLA-A24(+)) with chronic hepatitis B, six patients (HLA-A24(-)) with chronic h...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20194

    authors: Kondo Y,Asabe S,Kobayashi K,Shiina M,Niitsuma H,Ueno Y,Kobayashi T,Shimosegawa T

    更新日期:2004-11-01 00:00:00

  • Diagnosis of Oropouche virus infection by RT-nested-PCR.

    abstract::Using the RT-PCR with primers that anneal to the 5' and the 3' extremities of the genome segments of bunyaviruses and internal primers that anneal to the S segment of Simbu serogroup viruses in a nested PCR it was possible to amplify the Oropouche virus (ORO) genome from the sera of three patients. These results show ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.2122

    authors: Moreli ML,Aquino VH,Cruz AC,Figueiredo LT

    更新日期:2002-01-01 00:00:00

  • Hyperglycemia, hydroxychloroquine, and the COVID-19 pandemic.

    abstract::Coronavirus disease-2019 (COVID-19) infection and its severity can be explained by the concentration of glycosylated severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) viral particles in the lung epithelium, the concentration of glycosylated angiotensin-converting enzyme receptor 2 (ACE2) in the lung epithel...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/jmv.25887

    authors: Brufsky A

    更新日期:2020-07-01 00:00:00

  • Genotyping of human papillomavirus in cervical intraepithelial neoplasia in a high-risk population.

    abstract::Infection with the human papillomavirus (HPV) is responsible for 99.7% of cervical cancers, the second most prevalent neoplasia in women worldwide and the fifth leading cause of death by cancer in this population. In Chile, the incidence rate is 14.4 cases per 100,000 women per year and it is considered a significant ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.22057

    authors: Ili CG,Brebi P,López J,García P,Leal P,Suarez E,Roa JC

    更新日期:2011-05-01 00:00:00

  • Sex difference in the development of hepatocellular carcinoma after direct-acting antiviral therapy in patients with HCV infection.

    abstract::Sex differences in the predictors for hepatocellular carcinoma (HCC) development after direct-acting antiviral (DAA) therapy was investigated. DAA therapy was given to 1438 (663 male, 775 female) patients. Sex differences in the HCC development rate and the factors contributing to HCC development after DAA therapy wer...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25984

    authors: Watanabe T,Tokumoto Y,Joko K,Michitaka K,Horiike N,Tanaka Y,Tada F,Kisaka Y,Nakanishi S,Yamauchi K,Yukimoto A,Nakamura Y,Hirooka M,Abe M,Hiasa Y

    更新日期:2020-05-06 00:00:00

  • Unconventional pathogens causing spongiform encephalopathies absent in blood products.

    abstract::To determine whether unconventional pathogens causing subacute spongiform encephalopathy may be present in blood products, a newly developed hepatitis B vaccine and a widely used blood product were injected into mice and rats. As only a few aged mice in the test and the control groups showed spongiform encephalopathic...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890160103

    authors: Tateishi J,Tsuji S

    更新日期:1985-05-01 00:00:00

  • Human hepatitis B virus X protein augments the DNA binding of nuclear factor for IL-6 through its basic-leucine zipper domain.

    abstract::The X gene product of human hepatitis B virus, HBx, transactivates the expression of viral and cellular genes through a wide variety of cis elements, including the nuclear factor for IL-6 (NF-IL6) binding sites, although HBx does not appear to bind DNA directly. We previously reported that HBx transactivated the inter...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9071(199905)58:1<11::aid-jmv2>3

    authors: Ohno H,Kaneko S,Lin Y,Kobayashi K,Murakami S

    更新日期:1999-05-01 00:00:00

  • Comparison of the conventional multiplex RT-PCR, real time RT-PCR and Luminex xTAG® RVP fast assay for the detection of respiratory viruses.

    abstract::Detection of respiratory viruses using polymerase chain reaction (PCR) is sensitive, specific and cost effective, having huge potential for patient management. In this study, the performance of an in-house developed conventional multiplex RT-PCR (mRT-PCR), real time RT-PCR (rtRT-PCR) and Luminex xTAG(®) RVP fast assay...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24299

    authors: Choudhary ML,Anand SP,Tikhe SA,Walimbe AM,Potdar VA,Chadha MS,Mishra AC

    更新日期:2016-01-01 00:00:00

  • Ability of different lopinavir genotypic inhibitory quotients to predict 48-week virological response in highly treatment-experienced HIV-infected patients receiving lopinavir/ritonavir.

    abstract::The genotypic inhibitory quotient (GIQ) is the ratio between drug concentration and the number of resistance mutations. However, as different resistance scores can be calculated for the same protease inhibitor, the ability of a GIQ to predict the virological outcome may vary depending on the resistance score used as t...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20736

    authors: Gianotti N,Galli L,Danise A,Hasson H,Boeri E,Lazzarin A,Castagna A

    更新日期:2006-12-01 00:00:00

  • Epidemiological analysis of COVID-19 and practical experience from China.

    abstract::The rapid spread of the epidemic has aroused widespread concern in the international community. Severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) was first reported in China, with bats as the likely original hosts and pangolins as potential intermediate hosts. The current source of the disease is mainly pat...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,评审

    doi:10.1002/jmv.25813

    authors: Ye Q,Wang B,Mao J,Fu J,Shang S,Shu Q,Zhang T

    更新日期:2020-07-01 00:00:00

  • Influenza A virus in Taiwan, 1980-2006: Phylogenetic and antigenic characteristics of the hemagglutinin gene.

    abstract::Limited amount of information is available in Taiwan on the genetic or antigenic characteristics of influenza A virus prior to the establishment of a Taiwan surveillance network in 2000. Isolates of H1N1 and H3N2 viruses in Taiwan between 1980 and 2006 were studied, and part of the hemagglutinin gene was analyzed due ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21531

    authors: Wang SF,Lee YM,Chan YJ,Liu HF,Yen YF,Liu WT,Huang JC,Chen YM

    更新日期:2009-08-01 00:00:00