Recovery of functional cytotoxic T lymphocytes during lamivudine therapy by acquiring multi-specificity.

abstract：:During the 1998-1999 influenza season, two distinct influenza B virus Yamagata group strains were isolated from the patients of a private clinic. Each responded differently to monoclonal antibodies (Mabs) 5H4 and 8B3 on staining, and hemagglutination inhibition and neutralizing tests. When the analysis of nucleotide s...

journal_title：Journal of medical virology

authors： Nakagawa N,Kubota R,Morikawa S,Nakagawa T,Baba K,Okuno Y

更新日期：2001-12-01 00:00:00

abstract：:Herpes simplex virus (HSV) DNA in the cerebrospinal fluid (CSF) of children with herpes simplex encephalitis (HSE) was quantified and typed using the polymerase chain reaction (PCR) assay. During the acute phase, HSV-DNA was detected in the CSF of 13 patients with HSE, including 5 neonates. A restriction profile of th...

journal_title：Journal of medical virology

authors： Ando Y,Kimura H,Miwata H,Kudo T,Shibata M,Morishima T

更新日期：1993-10-01 00:00:00

abstract：:Mixed cryoglobulinemia is a lymphoproliferative disorder associated with hepatitis C virus (HCV). In patients chronically affected by HCV the prevalence of mixed cryoglobulinemia is variable ranging from 0% to 56%. To verify whether polyomaviruses (PyV) play a role in this disorder a total of 222 blood samples from 63...

journal_title：Journal of medical virology

authors： Comar M,Zanotta N,Del Savio R,Vascotto F,Calabrese N,Zorat F,Pozzato G

更新日期：2014-04-01 00:00:00

abstract：:Five temperature-sensitive mutants (tsm9, tsm13, tsm20, tsm22, tsm30) of murine cytomegalovirus have been shown previously not to produce infectious virus in mice. In the present study, the stage at which these mutants are blocked in their replication in vitro was examined by transcriptional analysis of 4 temporally r...

journal_title：Journal of medical virology

authors： Gill TA,Morley PJ,Sweet C

更新日期：2000-10-01 00:00:00

abstract：:The seroprevalence of antibodies to hepatitis E virus (HEV) and hepatitis A virus (HAV) was determined in a community-based sample in innercity London where socioeconomic conditions were expected to result in a high prevalence of antibodies to HAV, and in which the presence of immigrants from the developing world pose...

journal_title：Journal of medical virology

authors： Bernal W,Smith HM,Williams R

更新日期：1996-07-01 00:00:00

abstract：:Rapid PCR-based influenza tests are increasingly used as point-of-care diagnostics in hospitals and clinics. To our knowledge, no prior studies have described clinical outcomes with implementation of rapid PCR-based influenza tests in hospitalized adult inpatients. Electronic medical records were used to assess differ...

journal_title：Journal of medical virology

authors： Chu HY,Englund JA,Huang D,Scott E,Chan JD,Jain R,Pottinger PS,Lynch JB,Dellit TH,Jerome KR,Kuypers J

更新日期：2015-12-01 00:00:00

abstract：:Does anal HPV viral load explain the difference in anal HPV persistence between HIV-negative and -positive men who have sex with men (MSM)? MSM ≥18 years were recruited in Amsterdam, the Netherlands, in 2010-2011. Anal self-swabs were collected every 6 months and genotyped (SPF10 -PCR-DEIA-LIPA25 -system). HPV16 and H...

journal_title：Journal of medical virology

authors： Marra E,King A,van Logchem E,van der Weele P,Mooij SH,Heijman T,Meijer CJLM,Verhagen DWM,van der Sande MAB,Schim van der Loeff MF

更新日期：2018-01-01 00:00:00

abstract：:Hepatitis C virus (HCV) variation in specific T-cell epitopes may represent a mechanism of viral persistence in chronic infection. We examined the HCV non-structural protein 3 (NS3), including the immunologically relevant epitopes HCV NS3-2 KLVALGINAV (human leukocyte antigen [HLA]-A2-restricted) and HCV NS3-1391 LIFC...

journal_title：Journal of medical virology

authors： López-Labrador FX,He XS,Berenguer M,Cheung RC,González-Candelas F,Wright TL,Greenberg HB

更新日期：2004-04-01 00:00:00

abstract：:Little information is available on the impact of direct-acting antiviral (DAA) therapy on changes in liver fibrosis and steatosis. Liver stiffness (LS) and controlled attenuation parameter (CAP) values were evaluated using transient elastography. The study subjects were 214 elderly patients infected with HCV genotype ...

journal_title：Journal of medical virology

authors： Ogasawara N,Kobayashi M,Akuta N,Kominami Y,Fujiyama S,Kawamura Y,Sezaki H,Hosaka T,Suzuki F,Saitoh S,Suzuki Y,Arase Y,Ikeda K,Kobayashi M,Kumada H

更新日期：2018-02-01 00:00:00

abstract：:We developed an immunoperoxidase staining test to detect structural antigens of BK virus (BKV) in Vero cell cultures. This test was used to examine the neutralizing activity of human and immunized animal sera. It was shown that sera positive for BKV antibodies measured by hemagglutination inhibition test and enzyme-li...

journal_title：Journal of medical virology

authors： Flaegstad T,Traavik T,Christie KE,Joergensen J

更新日期：1986-07-01 00:00:00

abstract：:This study aimed to investigate the characteristics of female high-risk human papillomavirus (HR-HPV) infection in Shaanxi province of China. A total of 14 111 women were enrolled for HPV genotyping test, and a cytology, and/or cervix biopsy were performed in partial women. Of these women, the HPV infection rate was 3...

journal_title：Journal of medical virology

authors： Cao D,Zhang S,Zhang Q,Wei X,Zhao M,Ma Q,Li Y,Wang L,Pei M,Yang T,Zhao J,Yang X

更新日期：2017-07-01 00:00:00

abstract：:Interleukin 33 (IL-33) and soluble form of ST2 (sST2) are involved in inflammation. This study aimed to assess the role of serum IL-33 and sST2 in neonates with HCMV infection. The concentration of serum IL-33 and sST2 in 20 patients and 16 healthy controls were measure by enzyme-linked immune-sorbent assay (ELISA). T...

journal_title：Journal of medical virology

authors： Chen Y,Qian J

更新日期：2018-08-01 00:00:00

abstract：:Few studies have examined the etiology of hepatocellular carcinoma (HCC) in patients without hepatitis virus infection. We evaluated the role of occult hepatitis B virus (HBV) infection in the development of HCC in Japanese patients without hepatitis B surface antigen (HBsAg) and antibodies to hepatitis C antigen (ant...

journal_title：Journal of medical virology

authors： Tamori A,Nishiguchi S,Kubo S,Narimatsu T,Habu D,Takeda T,Hirohashi K,Shiomi S

更新日期：2003-12-01 00:00:00

abstract：:The risk and clearance of GB virus type C (GBV-C)/hepatitis G virus (HGV) infection was investigated in a cohort of homosexual men (n=180; median follow-up time, 7 years). The interaction between GBV-C/HGV RNA and antibodies against the E2 region of the virus, and the clinical impact of chronic GBV-C/HGV infection wer...

journal_title：Journal of medical virology

authors： Stark K,Doering CD,Bienzle U,Pauli G,Hamouda O,Engel AM,Schreier E

更新日期：1999-11-01 00:00:00

abstract：:A total of 18 rotavirus G9 strains in South Korea were collected during five rotavirus seasons between 2005 and 2010. The relationship between these strains was examined by analyzing the genetic variation of two major structural genes, VP7 and VP4. All the rotavirus isolates were of the G9P[8] genotype. The VP7 phylog...

journal_title：Journal of medical virology

authors： Than VT,Kang H,Lim I,Kim W

更新日期：2013-01-01 00:00:00

abstract：:Two major variables may cause false-negative results in prenatal diagnosis of congenital human cytomegalovirus (HCMV) infection: sensitivity of the techniques(s) used; and time elapsed between maternal infection and antenatal testing. Previous results indicated that rapid HCMV isolation from amniotic fluid samples and...

journal_title：Journal of medical virology

authors： Revello MG,Sarasini A,Zavattoni M,Baldanti F,Gerna G

更新日期：1998-09-01 00:00:00

abstract：:Chronic hepatitis B virus (HBV) infection is the result of an inadequate immune response towards the virus. Dendritic cells (DCs), as the most efficient professional antigen-presenting cells (APCs), possess the strongest antigen presenting the effect in the body and can stimulate the initial T cell activation and prol...

journal_title：Journal of medical virology

authors： Sun HH,Zhou DF,Zhou JY

更新日期：2016-01-01 00:00:00

abstract：:BK virus (BKV) establishes a persistent, asymptomatic infection in more than 80% of the human population, and in immunocompromised individuals BKV causes acute urinary tract infections. Two forms of BKV, archetype and rearranged, have been recovered previously from urine samples. The rearranged form is believed to hav...

journal_title：Journal of medical virology

authors： Chatterjee M,Weyandt TB,Frisque RJ

更新日期：2000-03-01 00:00:00

abstract：:The aim of the study was to evaluate the prevalence and risk factors of HPV in a gynecologic population attending outpatient clinics using two new molecular tests. The Amplicor HPV test and the Linear Array (LA) HPV Genotyping test were used for the detection of HPV DNA in 320 women. Multiple logistic regression was u...

journal_title：Journal of medical virology

authors： Papachristou E,Sypsa V,Paraskevis D,Gkekas A,Politi E,Nicolaidou E,Anifantis I,Psichogiou M,Tsitsika A,Hadjivassiliou M,Petrikkos G,Katsambas A,Creatsas G,Hatzakis A

更新日期：2009-12-01 00:00:00

abstract：:After an 8-day-old child had died with clinical signs of septicemia, 6 other newborns fell ill. Virus was isolated from various sites from all the 6 children (28 isolations). The agent was identified by cross neutralization tests as an antigenic variant of Echovirus 11. The agent could not be isolated from mothers or ...

journal_title：Journal of medical virology

authors： Mertens T,Hager H,Eggers HJ

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Seasonal influenza is an annual occurrence that leads to large community outbreaks and increased hospitalisation. A number of studies have suggested that influenza A (FLUAV) is associated with increased rates of hospitalisation and mortality compared to influenza B (FLUBV). This study compared demographic an...

journal_title：Journal of medical virology

authors： Mabayoje DA,Cutino-Moguel T,Haigh J,Wilks M,Welch CA,Melzer M

更新日期：2020-10-15 00:00:00

abstract：AIMS:Little data have been published so far on the epidemiological aspects of hepatitis D virus (HDV) infection in immigrant populations and even poorer is the information on the virological, phylogenetic, and clinical aspects of this infection in these populations. This review article, aimed primarily at physicians ca...

journal_title：Journal of medical virology

authors： Coppola N,Alessio L,Onorato L,Sagnelli C,Sagnelli E,Pisaturo M

更新日期：2019-12-01 00:00:00

abstract：:The emergence of genotypic resistance in protease and reverse transcriptase (RT) gene regions was longitudinally evaluated in plasma samples from a group of 12 HIV-1-infected patients treated with different combination of antiretroviral therapies and selected on the basis of their clinical failure. Complex mutational ...

journal_title：Journal of medical virology

authors： Cabana M,Clotet B,Martínez MA

更新日期：1999-12-01 00:00:00

abstract：:We studied epidemiologic and immunologic factors in infants with bronchiolitis caused by influenza virus. The proportion of these infants who were male and who had an immediate family member with a history of asthma was similar to that of a control group of infants with respiratory syncytial virus (RSV) bronchiolitis....

journal_title：Journal of medical virology

authors： Garofalo RP,Hintz KH,Hill V,Patti J,Ogra PL,Welliver RC Sr

更新日期：2005-02-01 00:00:00

abstract：:Investigation of varicella-zoster virus (VZV) is important epidemiologically, and determination of its prevalence rate in human trigeminal ganglia is important to provide surveillance data. To date, studies on VZV detection in trigeminal ganglia have used specimens obtained from a relatively limited number of cadavers...

journal_title：Journal of medical virology

authors： Inoue H,Motani-Saitoh H,Sakurada K,Ikegaya H,Yajima D,Hayakawa M,Sato Y,Otsuka K,Kobayashi K,Nagasawa S,Iwase H

更新日期：2010-02-01 00:00:00

abstract：:The characteristics and response rate to pegylated interferon and ribavirin (PEG-INF + RBV) of patients with chronic hepatitis C infected with genotype 5 are poorly documented. A meta-analysis of two large phase III/IV prospective randomized clinical trials conducted in Belgium in patients with chronic hepatitis C (n ...

journal_title：Journal of medical virology

authors： D'Heygere F,George C,Van Vlierberghe H,Decaestecker J,Nakad A,Adler M,Delwaide J,Laureys A,Nevens F

更新日期：2011-05-01 00:00:00

abstract：:The relative frequency and distribution of the VP4 (P) genotypes of 227 human rotavirus field strains were investigated in South Africa. The stool samples were collected between 1984-1993 from infants and young children with diarrhea at Ga-Rankuwa Hospital, Pretoria, South Africa. The RNA was extracted from stools, he...

journal_title：Journal of medical virology

authors： Mphahlele MJ,Steele AD

更新日期：1995-09-01 00:00:00

abstract：:Subviral particles of hepatitis B virus have been used to present foreign epitopes. We attempted to present the hydrophilic domains of E2 envelope protein of hepatitis C virus (HCV) as a fusion protein with hepatitis B virus surface antigen (HBsAg). The five hydrophilic domains of HCV E2 antigen were inserted into HBs...

journal_title：Journal of medical virology

authors： Lee IH,Kim CH,Ryu WS

更新日期：1996-10-01 00:00:00

abstract：:The criterion standard for the diagnosis of occult hepatitis C virus (HCV) infection is detection of HCV-RNA in liver cells. However, because of the invasive nature of liver biopsy, other methods have been studied. The present study aimed to identify subjects with occult HCV-4 infection among healthy sexual partners o...

journal_title：Journal of medical virology

authors： El Shazly Y,Hemida K,Rafik M,Al Swaff R,Ali-Eldin ZA,GadAllah S

更新日期：2015-03-01 00:00:00

abstract：:The effect of antiviral treatment on apoptosis in chronic hepatitis B (CHB) has not been clarified. We evaluated the hepatic immunohistochemical expression of the pro-apoptotic bax and the antiapoptotic bcl-xL protein in HBeAg-negative CHB patients before and after treatment. In our study we included 72 paired biopsie...

journal_title：Journal of medical virology

authors： Cholongitas E,Papatheodoridis GV,Manesis EK,Petraki K,Tiniakos D,Hadziyannis SJ

更新日期：2011-07-01 00:00:00