当前位置： SCI文献检索 > JOURNAL OF MEDICAL VIROLOGY期刊下所有文献 > Clustering patterns of type-type combination in multiple genotypes infections of human papillomavirus in cervical adenocarcinoma.

Clustering patterns of type-type combination in multiple genotypes infections of human papillomavirus in cervical adenocarcinoma.

Abstract：

:Coinfections with multiple types of human papillomavirus (HPV) occur in cervical adenocarcinoma (ADC). However, it remains unclear the clustering patterns of multiple types in HPV coinfections and relevant factors in ADC. A total of 718 paraffin-embedded ADC specimens were collected in China and tested for HPV genotypes using SPF10-INNO-LIPA. The prevalence of HPV coinfections and clustering patterns by geographical regions, histological subtypes and ages were assessed. Type-specific attribution of HPV to ADC adjusted by HPV coinfections were calculated. The prevalence of HPV coinfections was found to be 8.4% in ADC cases with slight variation by geographic regions between 2.2% and 12.5%. The 88.3% of all HPV multiple infections in ADC were two types of HPV coinfections with predominant combination of HPV 16 and HPV 18. The attribution to ADC was 88.0% for HPV 16/18 targeted by bivalent and quadrivalent vaccine and 96.8% for HPV 16/18/31/33/45/52/58 targeted by nonavalent vaccine. Clustering patterns of multiple types were related with histological categories and age at diagnosis. In conclusion, HPV coinfections are uncommonly prevalent in ADC cases with slight variation by geographic regions and distinct clustering patterns of multiple types by histological subtypes and ages at diagnosis. The high attribution of carcinogenic HPV types to ADC predicts potential protection of HPV vaccine against ADC.

journal_name

J Med Virol

journal_title

Journal of medical virology

authors

Dong L,Li T,Li L,Wang MZ,Wu Z,Cui J,Liu B,Zhang X,Qiao Y,Chen W

doi

10.1002/jmv.25553

subject

Has Abstract

pub_date

2019-11-01 00:00:00

pages

2001-2008

issue

11

eissn

0146-6615

issn

1096-9071

journal_volume

91

pub_type

杂志文章

相关文献

JOURNAL OF MEDICAL VIROLOGY文献大全
  • Seroepidemiological investigation of patients and family contacts in an epidemic of hepatitis A.

    abstract：:Serial blood and faecal samples were collected from patients and family contacts during an outbreak of hepatitis A in a village and tested by a solid-phase competitive type radioimmunoassay for hepatitis A antigen and hepatitis A antibody. The amount and duration of excretion of hepatitis A antigen was correlated with...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.1890010303

    authors： Frösner GG,Overby LR,Flehmig B,Gerth HJ,Haas H,Decker RH,Ling CM,Zuckerman AJ,Frösner HR

    更新日期：1977-01-01 00:00:00

  • Treatment with cytotoxic immunosuppression agents increases urinary excretion of JCV in patients with autoimmune disease.

    abstract：:Human JC virus is ubiquitous in human populations and is reactivated frequently in immunosuppressed patients. Fifty-one patients with autoimmune disease receiving immunomodulating therapy were evaluated to study the possible relationship between immunosuppression and JCV viruria. Patients were divided into cytotoxic a...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/1096-9071(200012)62:4<505::aid-jmv16>3.0.c

    authors： Wang M,Tsai RT,Ou WC,Lin CK,Tsay GJ,Chang H,Chang D

    更新日期：2000-12-01 00:00:00

  • The diagnosis of SARS-CoV2 pneumonia: A review of laboratory and radiological testing results.

    abstract：:The rapid emergence of coronavirus disease 2019 (COVID-19) has necessitated the implementation of diverse pandemic control strategies throughout the world. To effectively control the spread of this disease, it is essential that it be diagnosed at an early stage so that patients can be reliably quarantined such that di...

    journal_title：Journal of medical virology

    pub_type： 杂志文章,评审

    doi：10.1002/jmv.26081

    authors： Zheng Z,Yao Z,Wu K,Zheng J

    更新日期：2020-11-01 00:00:00

  • Laboratory and epidemiologic assessment of a recent influenza B outbreak.

    abstract：:A viral surveillance system in Nashville detected an outbreak of influenza B that occurred between January and March 1986. Paired sera from 32 individuals with culture-documented influenza B illness were tested using three serologic assays. Enzyme-linked immunosorbent assay (ELISA) using purified hemagglutinin-neurami...

    journal_title：Journal of medical virology

    pub_type： 临床试验,杂志文章

    doi：10.1002/jmv.1890250313

    authors： King JC Jr,Haugh CJ,Dupont WD,Thompson JM,Wright PF,Edwards KM

    更新日期：1988-07-01 00:00:00

  • Diagnosis of COVID-19 pneumonia despite missing detection of viral nucleic acid and initially inconspicuous radiologic findings.

    abstract：:The diagnosis of coronavirus disease 2019 (COVID-19) is mainly based on a positive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) polymerase chain reaction (PCR) result. PCR samples are obtained from upper or lower respiratory tract specimens. However, the sensitivity of PCR is known to have some limitat...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.26153

    authors： Schiller M,Wydra S,Kerl HU,Kick W

    更新日期：2020-11-01 00:00:00

  • Reactivation of human herpesvirus 6 by infection of human herpesvirus 7.

    abstract：:We have attempted to reactivate human herpesvirus 6 (HHV-6) by infection with HHV-7 using childhood exanthem subitum patients in vitro. Peripheral blood mononuclear cells (PBMCs) were collected from children who had a history of exanthem subitum(ES) by HHV-6 and were infected by human herpesvirus 7 (HHV-7) in vitro. T...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/(sici)1096-9071(200003)60:3<284::aid-jmv6>

    authors： Tanaka-Taya K,Kondo T,Nakagawa N,Inagi R,Miyoshi H,Sunagawa T,Okada S,Yamanishi K

    更新日期：2000-03-01 00:00:00

  • Pre-existing YMDD mutants in treatment-naïve patients with chronic hepatitis B are not selected during lamivudine therapy.

    abstract：:Although the rate at which mutations in the tyrosine-methionine-aspartate-aspartate (YMDD) motif of hepatitis B virus polymerase form is high during prolonged lamivudine (LAM) therapy, these mutations sometimes occur naturally in treatment-naïve patients with chronic hepatitis B. The prevalence of natural YMDD mutants...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.23191

    authors： Lee SH,Kim HS,Byun IS,Jeong SW,Kim SG,Jang JY,Kim YS,Kim BS

    更新日期：2012-02-01 00:00:00

  • Improved methods for quantification of human immunodeficiency virus type 1 RNA and hepatitis C virus RNA in blood using spin column technology and chemiluminescent assays of PCR products.

    abstract：:The quantification of human immunodeficiency virus type 1 (HIV-1) RNA or hepatitis C virus (HCV) RNA has been facilitated by adapting a spin column procedure for sample preparation and the use of chemiluminescent detection of polymerase chain reaction (PCR) products in microtiter plate format. All materials were comme...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：

    authors： Lin HJ,Tanwandee T,Hollinger FB

    更新日期：1997-01-01 00:00:00

  • The detection of SRAS-CoV-2 in outpatient clinics and public facilities during the COVID19 pandemic.

    abstract：:The transmission of the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) can occur through airborne route, in addition to contaminated surfaces and objects. In hospitals, it has been confirmed by several studies that SRAS-CoV-2 can contaminate surfaces and medical equipment especially in hospitals dedicat...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.26819

    authors： Elbadawy HM,Khattab A,Alalawi A,Aljohani F,Sundogji H,Mahmoud AS,Abouzied M,Eltahir HM,Alahmadey Z,Bahashwan S,Suliman BA

    更新日期：2021-01-26 00:00:00

  • Expression quantitative trait loci for TNFRSF10 influence both HBV infection and hepatocellular carcinoma development.

    abstract：:Tumor necrosis factor receptor superfamily member 10 (TNFRSF10) is a death domain-containing receptor for the apoptotic ligand TNFSF10, which involves multiple processes, including hepatocarcinogenesis and immune response against HBV infection. Several single nucleotide polymorphisms (SNPs) were identified as expressi...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.24363

    authors： Wen J,Song C,Liu J,Chen J,Zhai X,Hu Z

    更新日期：2016-03-01 00:00:00

  • Molecular analysis of HPV 16 E6I/E6II spliced mRNAs and correlation with the viral physical state and the grade of the cervical lesion.

    abstract：:The presence of HPV 16 E6*I/E6*II spliced transcripts, in cervical lesions of different grade, was analyzed to characterize the transcription pattern. The presence and amount of spliced transcripts were correlated with DNA viral markers such as E2/E6 ratio and physical state. The detection of HPV 16 E6*I/E6*II mRNAs w...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.21496

    authors： Cricca M,Venturoli S,Leo E,Costa S,Musiani M,Zerbini M

    更新日期：2009-07-01 00:00:00

  • Influence of HCV genotype and co-infection with human immunodeficiency virus on CD4(+) and CD8(+) T-cell responses to hepatitis C virus.

    abstract：:The role of T-cells in clearance of hepatitis C virus (HCV) during acute infection is critical. The relevance of the immunological response in the control of HCV replication is less clear in chronic HCV infection. HCV-specific T-cell responses were examined in 92 interferon-naive individuals with chronic hepatitis C. ...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.20856

    authors： Capa L,Soriano V,García-Samaniego J,Nuñez M,Romero M,Cascajero A,Muñoz F,González-Lahoz J,Benito JM

    更新日期：2007-05-01 00:00:00

  • Hepatitis E virus genotype 1f outbreak in Bangladesh, 2018.

    abstract：:Hepatitis E virus (HEV) infection is a significant public health issue in many developing countries, causing waterborne outbreaks as well as sporadic hepatitis. We report here an outbreak of HEV genotype 1f infection during April-May 2018 among people living at Halisohor, a low land in the southern part of Chottogram ...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.26739

    authors： Baki AA,Haque W,Giti S,Khan AA,Rahman MM,Jubaida N,Rahman M

    更新日期：2020-12-17 00:00:00

  • Severe metapneumovirus infections among immunocompetent and immunocompromised patients admitted to hospital with respiratory infection.

    abstract：:Human metapneumovirus (hMPV) is considered an important cause of acute respiratory infections. hMPV can cause morbidity in hematopoietic stem cell transplant recipients and recent research has demonstrated that it is an important virus in patients admitted to hospital with respiratory infections and suspected of havin...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.23477

    authors： Souza JS,Watanabe A,Carraro E,Granato C,Bellei N

    更新日期：2013-03-01 00:00:00

  • Matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 in the respiratory tracts of human infants following paramyxovirus infection.

    abstract：:Respiratory syncytial (RSV) and parainfluenza (PIV) viruses are primary causes of acute bronchiolitis and wheezing illnesses in infants and young children. To further understand inflammation in the airways following infection, we tested for the presence of matrix metalloproteinases (MMP) and natural tissue inhibitors ...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.20830

    authors： Elliott MB,Welliver RC Sr,Laughlin TS,Pryharski KS,LaPierre NA,Chen T,Souza V,Terio NB,Hancock GE

    更新日期：2007-04-01 00:00:00

  • A rapid DNA extraction method suitable for human papillomavirus detection.

    abstract：:Infection with oncogenic human papillomavirus (HPV) genotypes is necessary for the development of cervical cancer. Testing for HPV DNA from liquid based cervical samples can be used as an adjunct to traditional cytological screening. In addition there are ongoing viral load, genotyping, and prevalence studies. Therefo...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.23882

    authors： Brestovac B,Wong ME,Costantino PS,Groth D

    更新日期：2014-04-01 00:00:00

  • Serum concentrations of ribavirin and pegylated interferon and viral responses in patients infected with HIV and HCV.

    abstract：:The hepatitis C virus (HCV) infects a substantial proportion of patients infected with human immunodeficiency virus (HIV). Patients infected with both HCV and HIV respond poorly to anti-HCV treatment with pegylated interferon alpha and ribavirin. But few data are available on the influence of ribavirin and interferon ...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.21227

    authors： Nicot F,Legrand-Abravanel F,Lafont T,Dubois M,Sauné K,Pasquier C,Chatelut E,Izopet J

    更新日期：2008-09-01 00:00:00

  • Improved prenatal diagnosis of congenital human cytomegalovirus infection by a modified nested polymerase chain reaction.

    abstract：:Two major variables may cause false-negative results in prenatal diagnosis of congenital human cytomegalovirus (HCMV) infection: sensitivity of the techniques(s) used; and time elapsed between maternal infection and antenatal testing. Previous results indicated that rapid HCMV isolation from amniotic fluid samples and...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/(sici)1096-9071(199809)56:1<99::aid-jmv16>

    authors： Revello MG,Sarasini A,Zavattoni M,Baldanti F,Gerna G

    更新日期：1998-09-01 00:00:00

  • Prevalence of high-risk human papillomavirus infection among women in Shaanxi province of China: A hospital-based investigation.

    abstract：:This study aimed to investigate the characteristics of female high-risk human papillomavirus (HR-HPV) infection in Shaanxi province of China. A total of 14 111 women were enrolled for HPV genotyping test, and a cytology, and/or cervix biopsy were performed in partial women. Of these women, the HPV infection rate was 3...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.24748

    authors： Cao D,Zhang S,Zhang Q,Wei X,Zhao M,Ma Q,Li Y,Wang L,Pei M,Yang T,Zhao J,Yang X

    更新日期：2017-07-01 00:00:00

  • Serological and molecular prevalence of hepatitis E virus among blood donors from Uruguay.

    abstract：:Hepatitis E virus (HEV) infection is considered a neglected disease of major concern in developed countries. Clinically, HEV occurs as an acute and self-limited disease, though chronic cases mostly associated to HEV-3 are now being commonly reported in immunocompromised individuals and solid organ transplant recipient...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.26231

    authors： Bangueses F,Abin-Carriquiry JA,Cancela F,Curbelo J,Mirazo S

    更新日期：2020-06-27 00:00:00

  • The role of autophagy in human cytomegalovirus IE2 expression.

    abstract：:The purpose of this study was to determine whether autophagy regulates the expression of human cytomegalovirus (HCMV) immediately early two viral protein (IE2). Rapamycin and 3-methyladenine (3-MA) were used to stimulate or suppress autophagy during HCMV infection. UL122 recombinant plasmid was transfected to overexpr...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.26357

    authors： Zhang X,Xi T,Zhang L,Bi Y,Huang Y,Lu Y,Liu X,Fang F

    更新日期：2020-07-25 00:00:00

  • New amino acid changes in drug resistance sites and HBsAg in hepatitis B virus genotype H.

    abstract：:Long-term treatment with retrotranscriptase (RT) inhibitors eventually leads to the development of drug resistance. Drug-related mutations occur naturally and these can be found in hepatitis B virus (HBV) carriers who have never received antiviral therapy. HBsAg are overlapped with RT domain, thus nucleot(s)ide analog...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.24098

    authors： Fernández-Galindo DA,Sánchez-Ávila F,Bobadilla-Morales L,Gómez-Quiróz P,Bueno-Topete M,Armendáriz-Borunda J,Sánchez-Orozco LV

    更新日期：2015-06-01 00:00:00

  • Hepatitis E virus: molecular virology, clinical features, diagnosis, transmission, epidemiology, and prevention.

    abstract：:Hepatitis E virus (HEV), the sole member of the genus Hepevirus in the family of Hepeviridae, is the major cause of several outbreaks of waterborne hepatitis in tropical and subtropical countries and of sporadic cases of viral hepatitis in endemic and industrialized countries. Transmission of HEV occurs predominantly ...

    journal_title：Journal of medical virology

    pub_type： 杂志文章,评审

    doi：10.1002/jmv.21116

    authors： Mushahwar IK

    更新日期：2008-04-01 00:00:00

  • Clinical and immunological investigation of a new combined hepatitis A and hepatitis B vaccine.

    abstract：:As with hepatitis B vaccines, the recently developed hepatitis A vaccine is suitable not only for individual protection, but also for public health control measures. For introduction into routine immunisation programmes, however, hepatitis A vaccine should preferably be combined with other already established vaccines...

    journal_title：Journal of medical virology

    pub_type： 临床试验,杂志文章

    doi：10.1002/jmv.1890440426

    authors： Ambrosch F,Wiedermann G,André FE,Delem A,Gregor H,Hofmann H,D'Hondt E,Kundi M,Wynen J,Kunz C

    更新日期：1994-12-01 00:00:00

  • The prevalence of human papillomavirus in the oropharynx in healthy individuals in a Brazilian population.

    abstract：:Oncogenic human papillomavirus (HPV), a causative agent of uterine cervical cancer, has also been detected in head and neck squamous cell cancers, especially in squamous cell carcinomas of the tonsils. However, the true HPV prevalence in normal and neoplasic oropharyngeal mucosa remains uncertain. To determine the pre...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.20583

    authors： do Sacramento PR,Babeto E,Colombo J,Cabral Ruback MJ,Bonilha JL,Fernandes AM,Pereira Sobrinho JS,de Souza FP,Villa LL,Rahal P

    更新日期：2006-05-01 00:00:00

  • Genotyping of acute hepatitis a virus isolates from China, 2003-2008.

    abstract：:Hepatitis A virus (HAV) is usually transmitted by an oral-fecal route and is prevalent not only in developing countries but also in developed countries. In the present study, the phylogenetic characterization of the VP1/2A junction region (321 nucleotides) of China HAV isolates was examined. Anti-HAV IgM-positive seru...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.22086

    authors： Cao J,Bi S,Meng Q,Shen L,Zheng H,Zhang Y

    更新日期：2011-07-01 00:00:00

  • Typing of human papillomaviruses in condylomata acuminata from Greece.

    abstract：:DNA samples from recurrent condylomata acuminata biopsies of Greek males and females were examined for the presence of human papillomavirus (HPV) DNA using high-stringency Southern blot hybridization analysis. Of the twenty-six biopsies, 25 were positive for the HPV 6/11-related DNA sequences, and when further analyze...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.1890420311

    authors： Labropoulou V,Balamotis A,Tosca A,Rotola A,Mavromara-Nazos P

    更新日期：1994-03-01 00:00:00

  • Newly identified respiratory viruses in children with asthma exacerbation not requiring admission to hospital.

    abstract：:There are few data describing the comprehensive identification in and influence of newly identified respiratory viruses on asthma exacerbations. Most studies focus on inpatients. In this preliminary study, the point prevalence and the associations of picornavirus species described recently and human bocavirus (HBoV) w...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.21819

    authors： Arden KE,Chang AB,Lambert SB,Nissen MD,Sloots TP,Mackay IM

    更新日期：2010-08-01 00:00:00

  • Epidemiology and clinical features of rotavirus, adenovirus, and astrovirus infections and coinfections in children with acute gastroenteritis prior to rotavirus vaccine introduction in Meerut, North India.

    abstract：:There are limited reports on the etiology of multiple enteric viruses causing acute gastroenteritis (AGE) in North India. In the present study we have determined the prevalence of three enteric viruses, namely rotavirus, astrovirus (AstV) and adenovirus (AdV) in a total of 312 diarrheic children (<5 years) hospitalize...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.25645

    authors： Akdag AI,Gupta S,Khan N,Upadhayay A,Ray P

    更新日期：2020-08-01 00:00:00

  • Total HCV core antigen assay: a new marker of hepatitis C viremia for monitoring the progress of therapy.

    abstract：:The ability of the total hepatitis C virus (HCV) core antigen assay was evaluated for monitoring the therapeutic responses of HCV-infected patients treated with interferon. The ability to detect and quantitate an independent structural protein component of HCV, in the presence of circulating antibodies, makes this ass...

    journal_title：Journal of medical virology

    pub_type： 杂志文章

    doi：10.1002/jmv.10355

    authors： Zanetti AR,Romanò L,Brunetto M,Colombo M,Bellati G,Tackney C

    更新日期：2003-05-01 00:00:00