Predictors of human papilloma virus (HPV) infection in Italian women.

Abstract:

:HPV infection is a "necessary cause" of cervical cancer and it is sexually transmitted. Due to upcoming mass vaccination investigation on risk factors for infection is the basis to implement prophylactic strategy even in older women. The aim of the study was to evaluate predictors of high-risk (HR) HPV infection in adult women. Between 2006 and 2008, 100 women aged >18 years, with no previous treatment for cervical lesions, were screened for HR HPV infection in Rome, Italy. Risk factors for HPV infection were investigated through a questionnaire including: ethnicity, religion, education, marital status, sexual behavior, gynecological and obstetrical history, smoking and alcohol intake. Multivariate analysis identified the "never married-separated/divorced" status (OR: 3.38; 95% CI: 1.14-10.12) as predictor of HPV infection, while having a higher age at the first sexual intercourse (FSI) shows a protective effect (OR: 0.84; 95% CI: 0.71-1.00). A trend for the association between the infection and having more than three lifetime partners was also observed (OR: 2.57; 95% CI: 0.86-7.71). No significant association was found for other demographic characteristics investigated. These findings provide a contribution in the knowledge of an adult population defining a "high-risk" sexual behavioral profile and could be helpful to target prophylactic strategies in older woman.

journal_name

J Med Virol

authors

Cercato MC,Mariani L,Vocaturo A,Carrone A,Terrenato I,Morano G,Benevolo M,Rollo F,Germelli C,Paolini F,Venuti A

doi

10.1002/jmv.21887

subject

Has Abstract

pub_date

2010-11-01 00:00:00

pages

1921-7

issue

11

eissn

0146-6615

issn

1096-9071

journal_volume

82

pub_type

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