Norovirus infections and seroprevalence of genotype GII.4-specific antibodies in a Spanish population.

Abstract:

:Genotype II.4 noroviruses (NoVs) are a leading cause of epidemic acute gastroenteritis in children and adults worldwide. The prevalence of different NoV genotypes causing outbreaks and sporadic cases of acute gastroenteritis in the region of Valencia, Spain, during a 4-year period (2008-11) was investigated. NoVs were detected in 42 out of 55 (76.3%) outbreaks and in 26 out of 332 (7.8%) sporadic cases of acute gastroenteritis. Genogroup GII strains were predominant in outbreaks and sporadic cases. Different genotype GII.4 variants were found (Yerseke_2006a, Den Haag_2006b, Apeldoorn_2007, and New Orleans_2009), with the latter variant detected most frequently (35.3%). A recombinant P domain of the NoV GII.4 Apeldoorn_2007 variant was produced in Escherichia coli and used as the coating antigen in an enzyme immunoassay to survey the IgG antibody seroprevalence against NoV GII.4 in a Spanish population. Baculovirus-expressed virus-like particles (VLPs) of NoV GII.4 Den Haag_2006b variant were also produced and used as antigen to compare seroreactivity. Of the 434 serum specimens analyzed, 429 (98.6%) had antibodies against the P domain. The comparison of reactivities of 30 serum samples to the NoV GII.4 P polypeptide and VLP showed reproducible results with a correlation coefficient of r = 0.794. Titers of antibodies to the P domain increased gradually and significantly with age, reaching the highest levels at the age group of 41-50 years. These results confirm the high prevalence of NoV GII.4 infections in Valencia from early childhood.

journal_name

J Med Virol

authors

Carmona-Vicente N,Fernández-Jiménez M,Ribes JM,Téllez-Castillo CJ,Khodayar-Pardo P,Rodríguez-Diaz J,Buesa J

doi

10.1002/jmv.24112

subject

Has Abstract

pub_date

2015-04-01 00:00:00

pages

675-82

issue

4

eissn

0146-6615

issn

1096-9071

journal_volume

87

pub_type

杂志文章
  • Coronapp: A web application to annotate and monitor SARS-CoV-2 mutations.

    abstract::The avalanche of genomic data generated from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus requires the development of tools to detect and monitor its mutations across the world. Here, we present a webtool, coronapp, dedicated to easily processing user-provided SARS-CoV-2 genomic sequences and...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26678

    authors: Mercatelli D,Triboli L,Fornasari E,Ray F,Giorgi FM

    更新日期:2020-11-18 00:00:00

  • Absence of HTLV I from New Zealand.

    abstract::Sera from 1,943 individuals from Auckland, New Zealand, were tested for the presence of serum antibodies to human T cell lymphotropic virus I (HTLV I), mainly with an enzyme-linked immunosorbent assay (ELISA) with cell extracts as target antigen. The individuals tested were blood donors and mostly Caucasian, but inclu...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890220410

    authors: Reddy D,Okochi K,Woodfield DG,Judd W

    更新日期:1987-08-01 00:00:00

  • Contribution of common and recently described respiratory viruses to annual hospitalizations in children in South Africa.

    abstract::The contribution of viruses to lower respiratory tract disease in sub-Saharan Africa where human immunodeficiency virus may exacerbate respiratory infections is not well defined. No data exist on some of these viruses for Southern Africa. Comprehensive molecular screening may define the role of these viruses as single...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.22120

    authors: Venter M,Lassaunière R,Kresfelder TL,Westerberg Y,Visser A

    更新日期:2011-08-01 00:00:00

  • A rapid DNA extraction method suitable for human papillomavirus detection.

    abstract::Infection with oncogenic human papillomavirus (HPV) genotypes is necessary for the development of cervical cancer. Testing for HPV DNA from liquid based cervical samples can be used as an adjunct to traditional cytological screening. In addition there are ongoing viral load, genotyping, and prevalence studies. Therefo...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23882

    authors: Brestovac B,Wong ME,Costantino PS,Groth D

    更新日期:2014-04-01 00:00:00

  • Attenuated Junin virus infection in Callithrix jacchus.

    abstract::Twenty marmosets, male Callithrix jacchus, were used during this study. Fifteen of the marmosets were inoculated with 5,000 TCID50 of the attenuated XJC13 strain of Junin virus by intramuscular route and five were left as uninoculated controls. Animals were observed for a 420-day period. In order to carry out virologi...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890150112

    authors: Avila MM,Frigerio MJ,Weber EL,Rondinone S,Samoilovich SR,Laguens RP,de Guerrero LB,Weissenbacher MC

    更新日期:1985-01-01 00:00:00

  • Altered patterns of norovirus GII.b recombinant forms in gastroenteritis outbreaks in Victoria, Australia, 2002-2005 compared to 2006-2011.

    abstract::GII.b norovirus is an obligatory recombinant with an open reading frame (ORF) 1 comprising the GII.b genotype and the ORF 2 region corresponding to one of a number of other norovirus genotypes. GII.b is the second most common genotype after GII.4 associated with gastroenteritis outbreaks in Victoria, Australia. The st...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23633

    authors: Bruggink LD,Marshall JA

    更新日期:2013-08-01 00:00:00

  • Temporal distribution of human rotavirus serotypes 1,2,3, and 4 in Venezuelan children with gastroenteritis during 1979-1989.

    abstract::The temporal distribution and clinical severity of rotavirus VP7 serotypes 1, 2, 3, and 4 recovered from 427 Venezuelan children with acute gastroenteritis over a period of 11 years were studied. Rotavirus VP7 serotype was established by ELISA serotyping in 298 (69.78%) of the specimens while the serotype of the remai...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890340202

    authors: White L,García D,Boher Y,Blanco M,Pérez M,Romer H,Flores J,Pérez-Schael I

    更新日期:1991-06-01 00:00:00

  • Puumala virus and two genetic variants of Tula virus are present in Austrian rodents.

    abstract::Puumala and Tula viruses are hantaviruses found in Europe and are associated with the rodents Clethrionomys glareolus and Microtus arvalis, respectively. Puumala virus is associated with the human disease nephropathia epidemica. In Austria, ten clinically diagnosed cases of nephropathia epidemica, presumably caused by...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9071(199710)53:2<174::aid-jmv11

    authors: Bowen MD,Gelbmann W,Ksiazek TG,Nichol ST,Nowotny N

    更新日期:1997-10-01 00:00:00

  • Expression profiles of genes associated with viral entry in HCV-infected human liver.

    abstract::Recent studies have demonstrated that several cellular factors are involved in entry of hepatitis C virus (HCV) into host cells. Detailed gene expression profiles of these factors in HCV-infected livers have not been reported for humans. Transcriptional levels of LDL receptor (LDLR), CD81, scavenger receptor class B t...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.22042

    authors: Nakamuta M,Fujino T,Yada R,Aoyagi Y,Yasutake K,Kohjima M,Fukuizumi K,Yoshimoto T,Harada N,Yada M,Kato M,Kotoh K,Taketomi A,Maehara Y,Nakashima M,Enjoji M

    更新日期:2011-05-01 00:00:00

  • A rapid and efficient method BK polyomavirus genotyping by high-resolution melting analysis.

    abstract::A small percentage of renal patients become infected with the BK polyomavirus (BKV), a pathogenic virus that causes BKV-associated nephropathy (BKVN), after kidney transplantation. This study presents a simple, rapid, high-throughput method for BKV genotyping using high-resolution melt analysis (HRMA). Using this nove...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.22239

    authors: Matsuda Y,Qazi Y,Iwaki Y

    更新日期:2011-12-01 00:00:00

  • Scoring system for risk stratification of viral reactivation during prophylactic antiviral treatment in Korean patients with hepatitis B undergoing anticancer chemotherapy: A multicenter study.

    abstract::Prophylactic antiviral therapy is recommended for hepatitis B virus (HBV)-infected patients with malignancies who are undergoing systemic chemotherapy. In the current study, we aimed to develop a risk scoring system to guide the selection of prophylactic antiviral agents. In this retrospective analysis, we included co...

    journal_title:Journal of medical virology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/jmv.25241

    authors: Kim HY,Yoo JJ,Oh S,Yu SJ,Kim YJ,Yoon JH,Kim W,Jung YJ,Kim BH,Kim CM,Park JW,Lee JH

    更新日期:2018-10-01 00:00:00

  • The prevalence of human papillomavirus in the oropharynx in healthy individuals in a Brazilian population.

    abstract::Oncogenic human papillomavirus (HPV), a causative agent of uterine cervical cancer, has also been detected in head and neck squamous cell cancers, especially in squamous cell carcinomas of the tonsils. However, the true HPV prevalence in normal and neoplasic oropharyngeal mucosa remains uncertain. To determine the pre...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20583

    authors: do Sacramento PR,Babeto E,Colombo J,Cabral Ruback MJ,Bonilha JL,Fernandes AM,Pereira Sobrinho JS,de Souza FP,Villa LL,Rahal P

    更新日期:2006-05-01 00:00:00

  • Characterization of natural Epstein-Barr virus infection and replication in smooth muscle cells from a leiomyosarcoma.

    abstract::Cells from a leiomyosarcoma tumor (LMS-1) from a patient with the acquired immunodeficiency syndrome (AIDS) were explanted, cultured in vitro, and studied by phase-contrast microscopy for morphologic and growth characteristics, immunostaining for cell markers, EBER in situ hybridization and polymerase chain reaction f...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:

    authors: Jenson HB,Montalvo EA,McClain KL,Ench Y,Heard P,Christy BA,Dewalt-Hagan PJ,Moyer MP

    更新日期:1999-01-01 00:00:00

  • Infection with human T lymphotropic virus type I in organ transplant donors and recipients in Spain.

    abstract::Human T-cell lymphotropic virus (HTLV) antibody screening is not recommended uniformly before transplantation in Western countries. In the year 2001, the first cases of HTLV-I infection acquired through organ transplantation from one asymptomatic carrier were reported in Europe. All three organ recipients developed a ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20331

    authors: Toro C,Benito R,Aguilera A,Bassani S,Rodríguez C,Calderón E,Caballero E,Alvarez P,García J,Rodríguez-Iglesias M,Guelar A,del Romero J,Soriano V,HTLV Spanish Study Group.

    更新日期:2005-06-01 00:00:00

  • Human herpesvirus 6 variant a infects human term syncytiotrophoblasts in vitro and induces replication of human immunodeficiency virus type 1 in dually infected cells.

    abstract::Human herpesvirus 6 (HHV-6) and human immunodeficiency virus type 1 (HIV-1) may interact during transplacental transmission of HIV-1. The placental syncytiotrophoblast layer serves as the first line of defense of the fetus against viruses. Patterns of replication of HHV-6 variant A (HHV-6A) and HIV-1 were analyzed in ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.2194

    authors: Csoma E,Bácsi A,Liu X,Szabó J,Ebbesen P,Beck Z,Kónya J,Andirkó I,Nagy E,Tóth FD

    更新日期:2002-05-01 00:00:00

  • Diversity of hepatitis B and C viruses in Chile.

    abstract::Although there is a low prevalence rate (around 1% of the population) of infection with hepatitis B virus (HBV) and hepatitis C virus (HCV) in Chile, little is known about the diversity and molecular characteristics of the circulating viruses. In the present study, 40 HBV and 57 HCV samples from Santiago City, Chile, ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21607

    authors: Di Lello FA,Piñeiro Y Leone FG,Muñoz G,Campos RH

    更新日期:2009-11-01 00:00:00

  • Epidemiology of an outbreak in a maternity unit of infections with an antigenic variant of Echovirus 11.

    abstract::After an 8-day-old child had died with clinical signs of septicemia, 6 other newborns fell ill. Virus was isolated from various sites from all the 6 children (28 isolations). The agent was identified by cross neutralization tests as an antigenic variant of Echovirus 11. The agent could not be isolated from mothers or ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890090202

    authors: Mertens T,Hager H,Eggers HJ

    更新日期:1982-01-01 00:00:00

  • HEV and HAV seroprevalence in men that have sex with men (MSM): An update from Milan, Italy.

    abstract::Hepatitis E virus (HEV) is a feco-orally transmitted pathogen and one of the most common cause of acute hepatitis worldwide. Recent studies in developed countries suggested that a direct human-to-human contact such as for sexually transmitted diseases may play a significant role in the HEV spread. The aim of this stud...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.25052

    authors: Greco L,Uceda Renteria SC,Guarneri D,Orlandi A,Zoccoli A,Benardon S,Cusini M,Lunghi G

    更新日期:2018-08-01 00:00:00

  • Heterogeneous nature of HIV-1 recombinants spreading in Spain.

    abstract::HIV-1 infections due to non-B subtypes are increasing rapidly in number and spreading across Europe. The genetic nature of HIV-1 non-B variants containing subtype G sequences at the protease (PR)-coding region are described from 48 unrelated subjects living in Spain. Phylogenetic analyses of the HIV-1 reverse transcri...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20280

    authors: Holguín A,Alvarez A,Soriano V

    更新日期:2005-03-01 00:00:00

  • Hepatitis B infection of the liver in chronic hepatitis C without detectable hepatitis B virus DNA in serum.

    abstract::Hepatitis B virus (HBV) DNA may persist in the liver in the absence of serum HBV-DNA after a self-limited acute hepatitis B. This may also occur in patients with chronic hepatitis C virus (HCV) infection but its prevalence and its impact on liver histology is unknown. HBV-DNA was tested by polymerase chain reaction (P...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.20073

    authors: Mariscal LF,Rodríguez-Iñigo E,Bartolomé J,Castillo I,Ortiz-Movilla N,Navacerrada C,Pardo M,Pérez-Mota A,Graus J,Carreño V

    更新日期:2004-06-01 00:00:00

  • Increased prevalence of human herpesvirus type 8 (HHV-8) genome among blood donors from North-Western Argentina.

    abstract::The prevalence of HHV-8 infection varies widely in South American populations, displaying geographical variations in its distribution. The heterogeneous genetic contributions provided by the transatlantic parental populations that modified the Native American genomes may explain this epidemiological observation. Aimin...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24656

    authors: Hulaniuk ML,Torres O,Bartoli S,Fortuny L,Burgos Pratx L,Nuñez F,Salamone H,Corach D,Trinks J,Caputo M

    更新日期:2017-03-01 00:00:00

  • Serum concentrations of ribavirin and pegylated interferon and viral responses in patients infected with HIV and HCV.

    abstract::The hepatitis C virus (HCV) infects a substantial proportion of patients infected with human immunodeficiency virus (HIV). Patients infected with both HCV and HIV respond poorly to anti-HCV treatment with pegylated interferon alpha and ribavirin. But few data are available on the influence of ribavirin and interferon ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21227

    authors: Nicot F,Legrand-Abravanel F,Lafont T,Dubois M,Sauné K,Pasquier C,Chatelut E,Izopet J

    更新日期:2008-09-01 00:00:00

  • Novel application of a point mutation assay: evidence for transmission of hepatitis B viruses with precore mutations and their detection in infants with fulminant hepatitis B.

    abstract::Mutations of the precore region of hepatitis B virus (HBV) genome have been associated with fulminant and severe chronic hepatitis. However uncertainty remains about the clinical significance and transmissibility of these mutant strains. A point mutation assay (PMA) was developed to identify qualitatively and quantita...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890440105

    authors: Hawkins AE,Gilson RJ,Beath SV,Boxall EH,Kelly DA,Tedder RS,Weller IV

    更新日期:1994-09-01 00:00:00

  • Influenza A virus in Taiwan, 1980-2006: Phylogenetic and antigenic characteristics of the hemagglutinin gene.

    abstract::Limited amount of information is available in Taiwan on the genetic or antigenic characteristics of influenza A virus prior to the establishment of a Taiwan surveillance network in 2000. Isolates of H1N1 and H3N2 viruses in Taiwan between 1980 and 2006 were studied, and part of the hemagglutinin gene was analyzed due ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21531

    authors: Wang SF,Lee YM,Chan YJ,Liu HF,Yen YF,Liu WT,Huang JC,Chen YM

    更新日期:2009-08-01 00:00:00

  • Characterization of in vitro dengue virus resistance to carrageenan.

    abstract::The λ-carrageenan (λ-car) is a potent and selective inhibitor of dengue virus (DENV) infection targeted to virus adsorption and internalization, due to the structural similarities with the mammalian cell receptor heparan sulfate. To further characterize the antiviral activity of λ-car, the selection and the phenotypic...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.24457

    authors: Talarico LB,Damonte EB

    更新日期:2016-07-01 00:00:00

  • Risk and clearance of GB virus C/hepatitis G virus infection in homosexual men: A longitudinal study.

    abstract::The risk and clearance of GB virus type C (GBV-C)/hepatitis G virus (HGV) infection was investigated in a cohort of homosexual men (n=180; median follow-up time, 7 years). The interaction between GBV-C/HGV RNA and antibodies against the E2 region of the virus, and the clinical impact of chronic GBV-C/HGV infection wer...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/(sici)1096-9071(199911)59:3<303::aid-jmv7>

    authors: Stark K,Doering CD,Bienzle U,Pauli G,Hamouda O,Engel AM,Schreier E

    更新日期:1999-11-01 00:00:00

  • Weak correlation between antibody titers and neutralizing activity in sera from SARS-CoV-2 infected subjects.

    abstract::Plenty of serologic tests for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been developed so far, thus documenting the importance of evaluating the relevant features of the immune response to this viral agent. The performance of these assays is currently under investigation. Amongst them, LIAISON®...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.26605

    authors: Criscuolo E,Diotti RA,Strollo M,Rolla S,Ambrosi A,Locatelli M,Burioni R,Mancini N,Clementi M,Clementi N

    更新日期:2020-10-16 00:00:00

  • Seroprevalence rates of BKV, JCV, and MCPyV polyomaviruses in the general Czech Republic population.

    abstract::JC and BK polyomaviruses (JCV and BKV) infect humans and can cause severe illnesses in immunocompromised patients. Merkel cell polyomavirus (MCPyV) can be found in skin carcinomas. In this study, we assessed the occurrence of serum antibodies against MCPyV, BKV, and JCV polyomaviruses in a healthy population of the Cz...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.23841

    authors: Sroller V,Hamšíková E,Ludvíková V,Vochozková P,Kojzarová M,Fraiberk M,Saláková M,Morávková A,Forstová J,Němečková S

    更新日期:2014-09-01 00:00:00

  • Effect of age on serum immunoglobulin G subclass antibody responses to inactivated influenza virus vaccine.

    abstract::We previously reported an age-associated impairment of serum immunoglobulin G (IgG) antibody responses to inactivated influenza virus vaccine. The present study extends these observations by examining the IgG subclass distribution of vaccine responses measured by enzyme linked immunosorbent assay in healthy adults age...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.1890430111

    authors: Powers DC

    更新日期:1994-05-01 00:00:00

  • Epidemiological survey of enterovirus infections occurring in Taiwan between 2000 and 2005: analysis of sentinel physician surveillance data.

    abstract::Enterovirus (EV) infections are common. There are more than 60 known serotypes, and each has different epidemiologic or medical importance. Over 700 physicians from 75% of basic administrative units of Taiwan participated in the "Sentinel Physician Surveillance of Infectious Disease" and reported weekly to the Center ...

    journal_title:Journal of medical virology

    pub_type: 杂志文章

    doi:10.1002/jmv.21006

    authors: Tseng FC,Huang HC,Chi CY,Lin TL,Liu CC,Jian JW,Hsu LC,Wu HS,Yang JY,Chang YW,Wang HC,Hsu YW,Su IJ,Wang JR,CDC-Taiwan Virology Reference Laboratories and Sentinel Physician Network.

    更新日期:2007-12-01 00:00:00