Abstract:
:Human herpesvirus 6 (HHV-6), the etiologic agent of roseola in young children, has been reported to be detectable in the brain of many neurologically normal adults, although regional localization to plaques of multiple sclerosis has also been demonstrated. Large amounts of this virus were present in multifocal demyelinating white matter lesions of fulminant encephalomyelitis with seizures in a 21-year-old woman with normal immune parameters. Brain biopsy after 3 weeks of neurologic deterioration revealed a viral etiology by light and electron microscopy; the virus was identified as HHV-6 by immunohistochemistry and by polymerase chain reaction (PCR) amplification in biopsy and autopsy specimens.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Novoa LJ,Nagra RM,Nakawatase T,Edwards-Lee T,Tourtellotte WW,Cornford MEdoi
10.1002/(sici)1096-9071(199707)52:3<301::aid-jmv11subject
Has Abstractpub_date
1997-07-01 00:00:00pages
301-8issue
3eissn
0146-6615issn
1096-9071pii
10.1002/(SICI)1096-9071(199707)52:3<301::AID-JMV11journal_volume
52pub_type
杂志文章abstract::The emergence of genotypic resistance in protease and reverse transcriptase (RT) gene regions was longitudinally evaluated in plasma samples from a group of 12 HIV-1-infected patients treated with different combination of antiretroviral therapies and selected on the basis of their clinical failure. Complex mutational ...
journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:1999-12-01 00:00:00
abstract::The Gaza Strip borders the southern part of Israel and Egypt. There is a remarkable difference in the prevalence of antibodies to hepatitis C virus (HCV) between Israel (0.5%) and Egypt (10%). A few thousand inhabitants cross the borders daily from the Gaza Strip to both countries. The objectives of this study were to...
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pub_type: 临床试验,杂志文章
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abstract::Enterovirus 68 (EV-D68) was associated with mild to severe respiratory infections. In the last 4 years, circulation of different EV-D68 strains has been documented worldwide. In this study, the phylogenetic characterization of nine EV-D68 strains identified in patients in the 2010-2012 period and 12 additional EV-D68 ...
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journal_title:Journal of medical virology
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更新日期:2004-12-01 00:00:00
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journal_title:Journal of medical virology
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更新日期:2004-05-01 00:00:00
abstract::Capillary blood of febrile children was lysed by using a lysis buffer containing ascorbic acid. MxA quantitation was performed by an immunochemiluminescent assay. The MxA values were significantly higher in capillary blood of infants with viral infections due to adenovirus (n = 5), rotavirus (n = 15), or respiratory s...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:1999-12-01 00:00:00
abstract::The role of a novel virus, designated as TT virus (TTV), as a cause of chronic liver disease has not been well defined. We investigated the prevalence of TTV among 69 patients with chronic liver disease of unknown etiology and 50 volunteer blood donors with normal transaminase levels. TTV DNA was amplified by polymera...
journal_title:Journal of medical virology
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更新日期:2000-11-01 00:00:00
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journal_title:Journal of medical virology
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更新日期:1998-02-01 00:00:00
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journal_title:Journal of medical virology
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abstract::No controlled trial in patients with chronic hepatitis B virus (HBV) infection on long-term entecavir (ETV) treatment, comparing switching to tenofovir disoproxil fumarate (TDF) with continuing the therapy, has been reported. Twenty-seven nucleos(t)ide-naïve patients with chronic HBV who underwent ETV therapy for ≥5 y...
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pub_type: 杂志文章,随机对照试验
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abstract::Most dengue virus (DENV) infections remain asymptomatic. This increases the risk of DENV transfusion transmission (TT-DENV) during outbreaks. We evaluated DENV viremia in 8475 blood donations assembled in minipools for the presence of DENV RNA. The tested samples were obtained between February and May, 2016, during a ...
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journal_title:Journal of medical virology
pub_type: 临床试验,杂志文章,随机对照试验
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abstract::The Markov model was introduced to simulate natural histories of hepatitis C virus (HCV) infection in men and women. The data set was constructed on 942 HCV carriers who were examined at least once a year without receiving antiviral therapies. Based on 2,251 patient-year data, the probabilities of transition between a...
journal_title:Journal of medical virology
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journal_title:Journal of medical virology
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更新日期:1997-07-01 00:00:00
abstract::Stool specimens from 334 infants and young children hospitalized with diarrhea in the General Hospital, Kuala Lumpur, Malaysia between August and November, 1987 were analyzed for the presence of rotavirus double-stranded (ds) RNA by polyacrylamide gel electrophoresis. Of the 334 specimens analyzed, 32 (9.6%) were posi...
journal_title:Journal of medical virology
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abstract::Henan, China is characterized by the outbreak of HIV epidemic of Thai B strain in former plasma donors in 1990s. After the forbidden of paid blood donation, whether Thai B strain will spread out of former plasma donors into sexual transmitted population is unknown. To answer the question, phylogenetic analysis was use...
journal_title:Journal of medical virology
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abstract::Replication of HIV-1 inside host cells is dependent on both viral and host factors. MicroRNAs are small noncoding RNAs that regulate protein synthesis. MicroRNAs may control viral replication either by directly targeting the viral genome or indirectly through cellular proteins that are required during the viral lifecy...
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