Abstract:
:Human herpesvirus-8 (HHV-8) causes Kaposi's sarcoma (KS) and lymphoproliferative disorders in both HIV-infected and uninfected patients. HHV-8 has a worldwide occurrence but infection rates vary according to a combination of geographic and behavioral risks. The main transmission route seems to be sexual, nevertheless, nasal secretions, saliva, blood, and organ graft have been proposed. HHV-8 was postulated as a new infectious agent for screening in blood donors. The aim of this study was to evaluate the prevalence of antibodies against HHV-8 antigens in blood donors of South America. Serum samples from 2,470 blood donors from Argentina, Brazil, and Chile corresponding to five geographic regions were studied by indirect immunofluorescence assay (IFA). Seroprevalence rate was 3.7% (92/2,470; 95% CI 2.9-4.5) in the entire blood donor population distributed as follows: Argentina, 4.0% (Buenos Aires city, 4.3%; Bahia Blanca, 2.4%; and Córdoba, 4.0%), Campinas (Brazil), 2.8%; and Santiago de Chile, 3.0%. There was no difference (P>0.05) between men and women or age related, except in Brazil where positive cases were 30-49-year-old males. The present study, which includes different geographical areas of multiple countries from South America, has not been done before. The results show similar prevalence rates among the studied zones corresponding to low-prevalence regions. South America is a large sub-continent with a wide spectrum of population and geographical characteristics, thus, more HHV-8 prevalence studies should be necessary to establish possible regional differences.
journal_name
J Med Viroljournal_title
Journal of medical virologyauthors
Pérez C,Tous M,Gallego S,Zala N,Rabinovich O,Garbiero S,Martínez MJ,Cunha AM,Camino S,Cámara A,Costa SC,Larrondo M,Francalancia V,Landreau F,Bartomioli MAdoi
10.1002/jmv.20029keywords:
subject
Has Abstractpub_date
2004-04-01 00:00:00pages
661-7issue
4eissn
0146-6615issn
1096-9071journal_volume
72pub_type
杂志文章abstract::Our studies of rotavirus challenge in adult volunteers enabled us to evaluate the relationship of pre-existing antirotavirus fecal IgA antibody to infection and illness and to investigate the local response to this infection. No relationship could be found between the pre-existing levels of fecal antirotavirus IgA ant...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890200402
更新日期:1986-12-01 00:00:00
abstract::A sensitive microtitre radioimmunoassay was developed for detection of IgM antibodies to delta antigen. The assay was based on the selective binding of IgM from test sera to antihuman IgM (u-chain specific) fixed to wells of a microtitre plate, and utilized delta antigen extracted from the liver of an experimentally i...
journal_title:Journal of medical virology
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journal_title:Journal of medical virology
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:
更新日期:1999-02-01 00:00:00
abstract::Patients attending the genitourinary medicine clinic at Watford General Hospital, UK, were examined for clinical signs of genital herpes infection. Genital swabs were taken from 194 patients (126 female, 68 male) who presented with genital ulceration or symptoms which were suggestive of genital herpes infection. Swabs...
journal_title:Journal of medical virology
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更新日期:1998-06-01 00:00:00
abstract::The current Agence Nationale de Recherche sur le SIDA (ANRS)/International AIDS Society (IAS) algorithm predicts resistance to etravirine for viruses harboring >/=3 mutations from a list of 13 reverse transcriptase (RT) mutations. Two weighted algorithms, best correlated with fold changes to etravirine, have been desc...
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更新日期:2009-04-01 00:00:00
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更新日期:2008-06-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23240
更新日期:2012-07-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.24301
更新日期:2016-01-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890130307
更新日期:1984-01-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.25390
更新日期:2019-05-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890140106
更新日期:1984-01-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.20856
更新日期:2007-05-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890230412
更新日期:1987-12-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/(sici)1096-9071(199707)52:3<235::aid-jmv1>
更新日期:1997-07-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.1890190403
更新日期:1986-08-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
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journal_title:Journal of medical virology
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doi:10.1002/jmv.20363
更新日期:2005-07-01 00:00:00
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journal_title:Journal of medical virology
pub_type: 杂志文章
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更新日期:2005-10-01 00:00:00
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journal_title:Journal of medical virology
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journal_title:Journal of medical virology
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journal_title:Journal of medical virology
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journal_title:Journal of medical virology
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更新日期:1994-09-01 00:00:00
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journal_title:Journal of medical virology
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abstract::The complete RNA sequences of hepatitis delta viruses (HDV) isolated at 3 years apart from a chronic delta hepatitis patient in Taiwan were determined. The sequence analysis showed an overall evolution rate of 3.18 x 10(-3) substitutions/nucleotide/year. The evolution rates in different parts of HDV RNA varied. The hy...
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更新日期:1994-08-01 00:00:00