Changes in circulation of B and non-B HIV strains: spotlight on a reference centre for infectious diseases in Northern Italy.

abstract：:A new assay was developed for the detection of hepatitis B virus (HBV) in human serum using amplification of a short viral DNA sequence by means of the polymerase chain reaction. As little as 0.4 fg viral DNA, corresponding to about 130 genome equivalents, per ml serum could be detected after the amplification procedu...

journal_title：Journal of medical virology

authors： Sumazaki R,Motz M,Wolf H,Heinig J,Jilg W,Deinhardt F

更新日期：1989-04-01 00:00:00

abstract：:Enterovirus D68 (EV-D68) is an emergent viral pathogen associated with mild to severe respiratory infections. In this study, we describe respiratory infections associated with EV-D68 in Beijing over a 4 year period. Total nucleic acid was extracted from 7,945 clinical specimens collected between January 5, 2011 and Ju...

journal_title：Journal of medical virology

authors： Zhang T,Li A,Chen M,Wu J,Huang F

更新日期：2016-09-01 00:00:00

abstract：:Hepatitis A virus infections have been reported recently among hemophilic patients in Italy and Germany, leading to speculation that infectious hepatitis A virus (HAV) might have been present in some factor VIII concentrates. In both cases, the implicated factor concentrates had been treated by a solvent/detergent met...

journal_title：Journal of medical virology

authors： Murphy P,Nowak T,Lemon SM,Hilfenhaus J

更新日期：1993-09-01 00:00:00

abstract：:Coronavirus disease-2019 (COVID-19) infection and its severity can be explained by the concentration of glycosylated severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) viral particles in the lung epithelium, the concentration of glycosylated angiotensin-converting enzyme receptor 2 (ACE2) in the lung epithel...

journal_title：Journal of medical virology

authors： Brufsky A

更新日期：2020-07-01 00:00:00

abstract：:Although the rate at which mutations in the tyrosine-methionine-aspartate-aspartate (YMDD) motif of hepatitis B virus polymerase form is high during prolonged lamivudine (LAM) therapy, these mutations sometimes occur naturally in treatment-naïve patients with chronic hepatitis B. The prevalence of natural YMDD mutants...

journal_title：Journal of medical virology

authors： Lee SH,Kim HS,Byun IS,Jeong SW,Kim SG,Jang JY,Kim YS,Kim BS

更新日期：2012-02-01 00:00:00

abstract：:The epidemiology, transmission and clinical symptoms of human parechoviruses [HPeV, classified earlier as enteroviruses; echovirus 22 (HPeV1) and echovirus 23 (HPeV2)] remain poorly characterized. Enteroviruses and one parechovirus species, the Ljungan virus, have been associated with type 1 diabetes in humans and rod...

journal_title：Journal of medical virology

authors： Tauriainen S,Martiskainen M,Oikarinen S,Lönnrot M,Viskari H,Ilonen J,Simell O,Knip M,Hyöty H

更新日期：2007-04-01 00:00:00

abstract：:Saffold viruses (SAFV) have been discovered recently and they are classified into Theilovirus species in genus Cardiovirus in the Picornaviridae family. SAFV, especially those belonging to the genotype 2, have been difficult to propagate in laboratory cell lines. This study describes the successful isolation of an eff...

journal_title：Journal of medical virology

authors： Blomqvist S,Lappalainen M,Paananen A,Ylipaasto P,Roivainen M

更新日期：2012-09-01 00:00:00

abstract：:It is well documented that perinatal transmission is the major cause of chronic HBV infection in China. However, the mechanisms of HBV perinatal transmission are not defined clearly. It is not known whether hepatitis B e antigen can cross the human placenta, and the rate of HBeAg decay in babies with and without HBV b...

journal_title：Journal of medical virology

authors： Wang Z,Zhang J,Yang H,Li X,Wen S,Guo Y,Sun J,Hou J

更新日期：2003-11-01 00:00:00

abstract：:Attachment of hepatitis B virus to a hepatoblastoma cell line (HepG2) was examined using a synthetic peptide corresponding to the pre-S1 (21-47) region of the envelope protein. Scatchard analysis revealed a single class binding site of Kd 104 +/- 27 nM/l and 5.4 +/- 1.2 x 10(5) sites per cell. Competition of HBV with ...

journal_title：Journal of medical virology

authors： Dash S,Rao KV,Panda SK

更新日期：1992-06-01 00:00:00

abstract：:Previous studies on patients who develop drug resistant HIV-1 variants have shown that continued use of failing regimens might provide clinical benefit. However, the effect of long-term exposure to drug resistant variants may lead to emergence of compensatory mutations that may jeopardize this effect. In this study, w...

journal_title：Journal of medical virology

authors： Machouf N,Thomas R,Nguyen VK,Trottier B,Boulassel MR,Wainberg MA,Routy JP

更新日期：2006-05-01 00:00:00

abstract：:The avalanche of genomic data generated from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus requires the development of tools to detect and monitor its mutations across the world. Here, we present a webtool, coronapp, dedicated to easily processing user-provided SARS-CoV-2 genomic sequences and...

journal_title：Journal of medical virology

authors： Mercatelli D,Triboli L,Fornasari E,Ray F,Giorgi FM

更新日期：2020-11-18 00:00:00

abstract：:Five temperature-sensitive mutants (tsm9, tsm13, tsm20, tsm22, tsm30) of murine cytomegalovirus have been shown previously not to produce infectious virus in mice. In the present study, the stage at which these mutants are blocked in their replication in vitro was examined by transcriptional analysis of 4 temporally r...

journal_title：Journal of medical virology

authors： Gill TA,Morley PJ,Sweet C

更新日期：2000-10-01 00:00:00

abstract：:Few studies have examined the etiology of hepatocellular carcinoma (HCC) in patients without hepatitis virus infection. We evaluated the role of occult hepatitis B virus (HBV) infection in the development of HCC in Japanese patients without hepatitis B surface antigen (HBsAg) and antibodies to hepatitis C antigen (ant...

journal_title：Journal of medical virology

authors： Tamori A,Nishiguchi S,Kubo S,Narimatsu T,Habu D,Takeda T,Hirohashi K,Shiomi S

更新日期：2003-12-01 00:00:00

abstract：:Nitric oxide is well accepted as one of the defenses for inhibiting viral dissemination. Macrophages and cells in the macrophage lineage are professional nitric oxide producers which sub-serve as target for dengue virus. The interaction between nitric oxide and dengue virus in such target cell is unknown. In this repo...

journal_title：Journal of medical virology

authors： Charnsilpa W,Takhampunya R,Endy TP,Mammen MP Jr,Libraty DH,Ubol S

更新日期：2005-09-01 00:00:00

abstract：:Glycoproteins of enveloped viruses replicating in nonprimate mammalian cells carry α-1,3-galactose (α-Gal) glycans, and can bind to anti-Gal antibodies which are abundant in humans. The antibodies have protected humans and their ancestors for millions of years, because they inhibit replication of many kinds of microbe...

journal_title：Journal of medical virology

authors： Chen JM

更新日期：2020-07-18 00:00:00

abstract：:Dual infection with hepatitis B and C viruses is often encountered in endemic areas of both viruses. However, understanding of the clinical and virological implications is limited. The aim of this study was to investigate the role of each virus in liver injury and the interaction between the two viruses in dual infect...

journal_title：Journal of medical virology

authors： Ohkawa K,Hayashi N,Yuki N,Masuzawa M,Kato M,Yamamoto K,Hosotsubo H,Deguchi M,Katayama K,Kasahara A

更新日期：1995-07-01 00:00:00

abstract：:The immunogenicity of the Russian cold-adapted (ca) donor stains, A/Leningrad (Len)/134/17/57 and A/Leningrad/134/47/57, and the US strain A/Ann Arbor (AA)/6/60-ca, were compared in BALB/c mice with their respective wild-type parental viruses. Each ca donor strain was less immunogenic than its wild-type parent. The va...

journal_title：Journal of medical virology

authors： Wareing MD,Watson JM,Brooks MJ,Tannock GA

更新日期：2001-09-01 00:00:00

abstract：:Rotavirus vaccines have been available in Japan since 2011. This study conducted to monitor the trend of group A rotavirus (RVA) genotypes 3 years after vaccine introduction. A total of, 539 fecal samples were collected from children with acute gastroenteritis in six regions during July 2014-June 2015. Among them, 178...

journal_title：Journal of medical virology

authors： Khandoker N,Thongprachum A,Takanashi S,Okitsu S,Nishimura S,Kikuta H,Yamamoto A,Sugita K,Baba T,Kobayashi M,Hayakawa S,Mizuguchi M,Ushijima H

更新日期：2018-06-01 00:00:00

abstract：:Mitochondrial DNA (mtDNA) of peripheral blood mononuclear cells (PBMCs) collected from Human immunodeficiency virus 1 (HIV-1)-infected patients and healthy controls were measured longitudinally using real-time polymerase chain reaction to evaluate the effects of antiretroviral agents on mtDNA synthesis in vivo and to ...

journal_title：Journal of medical virology

authors： Miura T,Goto M,Hosoya N,Odawara T,Kitamura Y,Nakamura T,Iwamoto A

更新日期：2003-08-01 00:00:00

abstract：:Comparison of RT-PCR assays established in house at various places revealed that laboratories could differ in sensitivity by as much as 1,000-fold in terms of the ability to detect measles virus sequences in clinical samples. The study indicates that PCR findings, positive or negative, are questionable if they are not...

journal_title：Journal of medical virology

authors： Afzal MA,Osterhaus AD,Cosby SL,Jin L,Beeler J,Takeuchi K,Kawashima H

更新日期：2003-05-01 00:00:00

abstract：:The relationships between host immune factors and HIV-1 disease progression are still in dispute. The RANTES SNPs exhibit distinct ethnic distribution and are associated with different effects on the course of HIV infection. Therefore, impact of RANTES gene polymorphism on HIV-1 transmission and progression needs to b...

journal_title：Journal of medical virology

authors： Rathore A,Chatterjee A,Sivarama P,Yamamoto N,Singhal PK,Dhole TN

更新日期：2008-07-01 00:00:00

abstract：:The detection of hepatitis B virus (HBV) DNA plays a critical role in determining the level of viral replication in HBV-infected patients. However, how to select appropriate HBV DNA detection method, low-sensitivity (ls) and hypersensitivity (hs) remains unclear. In this study, hepatitis B surface antigen (HBsAg), hep...

journal_title：Journal of medical virology

authors： Liu C,Wu W,Shang S,Huang E,Xun Z,Lin J,Chen T,Yang B,Chen J,Ou Q

更新日期：2019-02-01 00:00:00

abstract：:Puumala and Tula viruses are hantaviruses found in Europe and are associated with the rodents Clethrionomys glareolus and Microtus arvalis, respectively. Puumala virus is associated with the human disease nephropathia epidemica. In Austria, ten clinically diagnosed cases of nephropathia epidemica, presumably caused by...

journal_title：Journal of medical virology

authors： Bowen MD,Gelbmann W,Ksiazek TG,Nichol ST,Nowotny N

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:Human metapneumovirus (hMPV) is a recently detected virus, which can cause mild to severe respiratory tract infections. Through this study, we aimed to detail the outcomes of hMPV infections. MATERIALS/METHODS:Between January 2012 and November 2017, patients who had hMPV detected in nasopharyngeal or bronch...

journal_title：Journal of medical virology

authors： Keske Ş,Gümüş T,Köymen T,Sandıkçı S,Tabak L,Ergönül Ö

更新日期：2019-06-01 00:00:00

abstract：:Genotype 1F was likely localized geographically to China as it has not been reported elsewhere. In this study, whole genome sequences of two rubella 1F virus isolates were completed. Both viruses contained 9,761 nt with a single nucleotide deletion in the intergenic region, compared to the NCBI rubella reference seque...

journal_title：Journal of medical virology

authors： Zhu Z,Chen MH,Abernathy E,Zhou S,Wang C,Icenogle J,Xu W

更新日期：2014-12-01 00:00:00

abstract：:Influenza A/H3N2 viruses are associated with severe epidemics. Antiviral resistance and continued antigenic drift are the major concerns regarding prophylaxis and treatment of influenza. The objectives of this study were to investigate the prevalence and frequency of antiviral drug resistance in influenza A/H3N2 virus...

journal_title：Journal of medical virology

authors： Cai J,Wang X,Zhao B,Yao W,Wang X,Zhu Q,Zeng M

更新日期：2014-06-01 00:00:00

abstract：:A total of 190 specimens from South Indian children aged 0-59 months with ocular anomalies consistent with suspected congenital rubella syndrome (CRS) were investigated. Twenty-six of the 65 infants (40%) were confirmed as CRS by detection of rubella specific IgM. Rubella RNA was detected in 41 samples from 26 infants...

journal_title：Journal of medical virology

authors： Rajasundari TA,Sundaresan P,Vijayalakshmi P,Brown DW,Jin L

更新日期：2008-03-01 00:00:00

abstract：:Cervical specimens collected from 163 cytologically healthy women were screened for the presence of human papillomavirus (HPV) DNA and anti-HPV secretory IgA antibodies. HPV DNA was detected by a general primer mediated polymerase chain reaction (PCR), which amplifies a conserved region from the L1 ORF of genital HPVs...

journal_title：Journal of medical virology

authors： Veress G,Kónya J,Csiky-Mészáros T,Czeglédy J,Gergely L

更新日期：1994-06-01 00:00:00

abstract：:Simian immunodeficiency virus (SIV) as well as human immunodeficiency virus (HIV) induce polyclonal B-cell activation and are associated with the appearance of lymphomas in their respective hosts in either the presence or the absence of other co-infecting viruses such as Epstein-Barr virus (EBV). However, the pathogen...

journal_title：Journal of medical virology

authors： Titti F,Zamarchi R,Maggiorella MT,Sernicola L,Geraci A,Negri DR,Borsetti A,Menin C,D'Andrea E,Modesti A,Masuelli L,Verani P,Chieco-Bianchi L,Amadori A

更新日期：2002-09-01 00:00:00

abstract：:A viral surveillance system in Nashville detected an outbreak of influenza B that occurred between January and March 1986. Paired sera from 32 individuals with culture-documented influenza B illness were tested using three serologic assays. Enzyme-linked immunosorbent assay (ELISA) using purified hemagglutinin-neurami...

journal_title：Journal of medical virology

authors： King JC Jr,Haugh CJ,Dupont WD,Thompson JM,Wright PF,Edwards KM

更新日期：1988-07-01 00:00:00